References
- Classification of Chronic PainDescriptions of chronic pain syndromes and definitions of pain terms. Prepared by the International Association for the Study of Pain, Subcommittee on TaxonomyPain Suppl19863S1226 Available from: https://s3.amazonaws.com/rdcms-iasp/files/production/public/Content/ContentFolders/Publications2/Free-Books/Classification-of-Chronic-Pain.pdfAccessed March, 24, 20183461421
- BestrashniyJWintersKCVariability in medical marijuana laws in the United StatesPsychol Addict Behav20152963964226415061
- LightMKOrensALewandowskiBMarket size and demand for marijuana in ColoradoThe Marijuana Policy Group2014 Available from: http://www.cannabisconsumer.org/uploads/9/7/9/6/97962014/market_size_and_demand_study_july_9_2014%5B1%5D.pdfAccessed November 17, 2016
- IlgenMABohnertKKleinbergFCharacteristics of adults seeking medical marijuana certificationDrug Alcohol Depen2013132654659
- HillKPPalastroMDJohnsonBDitreJWCannabis and pain: a clinical reviewCannabis Cannabinoid Res2017219610428861509
- MatsudaLALolaitSJBrownsteinMJYoungACBonnerTIStructure of a cannabinoid receptor and functional expression of the cloned cDNANature19903465615642165569
- MunroSThomasKLAbu-ShaarMMolecular characterization of a peripheral receptor for cannabinoidsNature199336561657689702
- BreivogelCSGriffinGDi MarzoVMartinBREvidence for a new G-protein-coupled cannabinoid receptor in mouse brainMol Pharmacol20016015516311408610
- Di MarzoVBreivogelCSTaoQLevels, metabolism, and pharmacological activity of anandamide in CB1 cannabinoid receptor knockout mice, evidence for non-CB1, non-CB2 receptor-mediated actions of anandamide in mouse brainJ Neurochem2000752434244411080195
- HájosNLedentCFreundTFNovel cannabinoid sensitive receptor mediates inhibition of glutamatergic synaptic transmission in the hippocampusNeuroscience200110614
- ManzanaresJJulianMDCarrascosaARole of the cannabinoid system in pain control and therapeutic implications for the management of acute and chronic pain episodesCurr Neuropharmacol20064323925718615144
- Health Canada [webpage on the Internet]Information for health care professionalsCannabis (marihuana, marijuana) and the cannabinoidsHealth Canada2013 Available from: https://www.canada.ca/en/health-canada/services/drugs-health-products/medical-use-marijuana/information-medical-practitioners/information-health-care-professionals-cannabis-marihuana-marijuana-cannabinoids.htmlAccessed March, 24, 2018
- CridgeBJRosengrenRJCritical appraisal of the potential use of cannabinoids in cancer managementCancer Management Res20135301315
- McAllisterSDSoroceanuLDesperzPYThe antitumor activity of plant-derived non-psychoactive cannabinoidsJ Neuroimmune Pharmacol201510225526725916739
- AbramsDIGuzmanMCannabis in cancer careClin Pharmacol Ther20159757558625777363
- McPartlandJMRussoEBCannabis and cannabis extracts: greater than the sum of their parts?J Cannabis Therapeut20011103132
- RussoEBGuyGWA tale of two cannabinoids: the therapeutic rationale for combining tetrahydrocannabinol and cannabidiolMed Hypotheses2006662344616209908
- RussoEBCannabinoids in the management of difficult to treat painTher Clin Risk Manag20084124525918728714
- European Medicines Agency [webpage on the Internet]EMEA-001902-PIP01-15-M01 Available from: http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/pips/EMEA-000181-PIP02-13/pip_001257.jsp&mid=WC0b01ac058001d129Accessed March, 24, 2018
- European Medicines Agency [webpage on the Internet]EU/3/16/1621 Available from: http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/orphans/2016/04/human_orphan_001722.jsp&mid=WC0b01ac058001d12bAccessed March, 24, 2018
- WadeDTCollinCStottCDuncombePMeta-analysis of the efficacy and safety of Sativex (nabiximols) on spasticity in people with multiple sclerosisMult Scler20101670771420558502
- ZajicekJBallSWrightDEffect of dronabinol on progression in progressive multiple sclerosis (CUPID): a randomized, placebo-controlled trialLancet Neurol20131285786523856559
- BallSVickeryJHobartJThe cannabinoid use in progressive inflammatory brain disese (CUPID) trial: a randomized dobule-blind placebo-controlled parallel-group multicenter trial and economic evaluation of cannabinoids to slow progression in multiple sclerosisHealth Technol Assess20151912viiviiixxvxxxi1187
- CollinCDaviesPMutibokoIKRatcliffeSSativex Spasticity in MS Study GroupRandomized controlled trial of cannabis-based medicine in spasticity caused by multiple sclerosisEur J Neurol20071429029617355549
- CollinCEhlerEWaberzinekGA double-blind, randomized, placebo-controlled, parallel group study of Sativex in subjects with symptoms of spasticity due to multiple sclerosisNeurol Res20103245145920307378
- NotcuttWLangfordRDaviesPRatcliffeSPottsRA placebo-controlled, parallel-group randomized withdrawal study of subjects with symptoms of spasticity due to multiple sclerosis who are receiving long-term Sativex (nabiximols)Mult Scler20121821922821878454
- NovotnaAMaresJRatcliffeSA randomized, double-blind, placebo-controlled, parallel-group enriched-design study of nabiximols (Sativex) as add-on therapy in subjects with refractory spasticity caused by multiple sclerosisEur J Neurol2011181122113121362108
- WadeDTMakelaPRobsonPHouseHBatemanCDo cannabis-based medicinal extracts have general or specific effects on symptoms in multiple sclerosis? A double-blind, randomized, placebo-controlled study of 160 patientsMult Scler20041043444115327042
- ZajicekJFoxPSandersHCannabinoids for treatment of spasticity and other symptoms related to multiple sclerosis (CAMS study): multicenter randomized placebo-controlled trialLancet20033621517152614615106
- Corey-BloomJWolfsonTGamstASmoked cannabis for spasticity in multiple sclerosis: a randomized, placebo-controlled trialCMAJ20121841143115022586334
- RogDJNurmikkoTJFriedeTYoungCARandomized controlled trial of cannabis-based medicine in central pain in multiple sclerosisNeurology20056581281916186518
- PhillipsTJCCherryCLCoxSMarshallSJRiceASPharmacological treatment of painful HIV-associated sensory neuropathy: a systematic review and meta-analysis of randomized controlled trialsPlos One2010512e1443321203440
- AbramsDIHiltonJFLeiserRJShort-term effects of cannabinoids in patients with HIV-1 infection: a randomized placebo-controlled clinical trialAnn Intern Med200313925826612965981
- AbramsDIJayCAShadeSBCannabis in painful HIV-associated sensory neuropathyNeurology20076851552117296917
- EllisRJToperoffWVaidaFvan den BrandeGSmoked medicinal cannabis for neuropathic pain in HIV: a randomized, crossover clinical trialNeuropsychopharmacology20093467268018688212
- AshtonJCEmerging treatment options for spasticity in multiple sclerosis – clinical utility of cannabinoidsDeg Neurol Neuromusc Dis201111523
- LynchMECampbellFCannabinoids for treatment of chronic non-cancer pain; a systematic review of randomized trialsBr J Clin Phar-macol201172735744
- Martín-SánchezEFurukawaTATaylorJMartinJLSystematic review and meta-analysis of cannabis treatment for chronic painPain Med2009101353136819732371
- Ben AmarMCannabinoids in medicine: a review of their therapeutic potentialJ Ethnopharmacol200610512516540272
- JohnsonJRBurnell-NugentMLossignolDGanae-MotanEDPottsRFallonMTMulticenter, double-blind, randomized, placebo-controlled, parallel-group study of the efficacy, safety and tolerability of THC:CBD extract and THC extract in patients with intractable cancer-related painJ Pain Symptom Manage20103916717919896326
- JohnsonJRLossignolDBurnell-NugentMFallonMTAn open-label extension study to investigate the long-term safety and tolerability of THC/CBD oromucosal spray and oromucosal THC spray in patients with terminal cancer-related pain refractory to strong opioid analgesicsJ Pain Symptom Manage20134620721823141881
- PortenoyRKBanae-MotanEDAllendeSNabiximols for opioid-treated cancer patients with poorly-controlled chronic pain: a randomized placebo-controlled dose-graded trialJ Pain20121343844922483680
- IversenLChapmanVCannabinoids, a real prospect for pain relief?Curr Opin Pharmacol20022505511786308
- PertweeRGCannabinoid receptors and painProg Neurobiol20016356961111164622
- IversenLCannabis and the brainBrain20031261252127012764049
- HigginsJPTGreenSCochrane Handbook for Systematic Reviews of Interventions [webpage on the Internet]. Version 5.1.O (updated March 2011) Available from: http://handbook.cochrane.org/Accessed June 23, 2017
- Centre for Reviews and DisseminationSystematic Reviews: CRD’s Guidance for Undertaking Reviews in Health CareYork, UKUniversity of York2009 Available from: https://www.york.ac.uk/media/crd/Systematic_Reviews.pdfAccessed June 23, 2017