Cognitive Inhibition Correlates with Exercise-Induced Hypoalgesia After Aerobic Bicycling in Pain-Free Participants

References

• Ossipov MH, Morimura K, Porreca F. Descending pain modulation and chronification of pain. Curr Opin Support Palliat Care. 2014;8(2):143–151. doi:10.1097/SPC.0000000000000055
   PubMed Web of Science ®Google Scholar
• Yarnitsky D. Role of endogenous pain modulation in chronic pain mechanisms and treatment. Pain. 2015;156(Suppl 1):S24–31. doi:10.1097/01.j.pain.0000460343.46847.58
   PubMed Web of Science ®Google Scholar
• Naugle KM, Fillingim RB, Riley JL. A meta-analytic review of the hypoalgesic effects of exercise. J Pain. 2012;13(12):1139–1150. doi:10.1016/j.jpain.2012.09.006
   PubMed Web of Science ®Google Scholar
• Rice D, Nijs J, Kosek E, et al. Exercise-induced hypoalgesia in pain-free and chronic pain populations: state of the art and future directions. J Pain. 2019;20(11):1249–1266. doi:10.1016/j.jpain.2019.03.005
   PubMed Web of Science ®Google Scholar
• Vaegter HB, Lyng KD, Yttereng FW, Christensen MH, Sørensen MB, Graven-Nielsen T. Exercise-induced hypoalgesia after isometric wall squat exercise: a test-retest reliability study. Pain Med. 2019a;20(1):129–137. doi:10.1093/pm/pny087
   PubMed Web of Science ®Google Scholar
• Ohlman T, Miller L, Naugle KE, Naugle KM. Physical activity levels predict exercise-induced hypoalgesia in older adults. Med Sci Sports Exerc. 2018;50(10):2101–2109. doi:10.1249/MSS.0000000000001661
   PubMed Web of Science ®Google Scholar
• Awali A, Nevsimal R, O’Melia S, Alsouhibani A, Bement MH. The contribution of experimental pain to the sex differences in exercise-induced hypoalgesia. J Pain. 2019;20(4):S50–S50.
   Web of Science ®Google Scholar
• Peterson JA, Schubert DJ, Campbell J, Bemben MG, Black CD. Endogenous pain inhibitory function: endurance-trained athletes vs active controls. Pain Med. 2019;20(9):1822–1830. doi:10.1093/pm/pnz014
   PubMed Web of Science ®Google Scholar
• Smith A, Ritchie C, Pedler A, McCamley K, Roberts K, Sterling M. Exercise induced hypoalgesia is elicited by isometric, but not aerobic exercise in individuals with chronic whiplash associated disorders. Scand J Pain. 2017;15(1):14–21. doi:10.1016/j.sjpain.2016.11.007
   PubMedGoogle Scholar
• Brellenthin AG, Cook D, Sehgal N, Koltyn KF. Exercise-induced hypoalgesia and pain catastrophizing in women and men. Med Sci Sports Exerc. 2013;45(5):280.
   Web of Science ®Google Scholar
• Naugle KM, Naugle KE, Fillingim RB, Riley JL. Isometric exercise as a test of pain modulation: effects of experimental pain test, psychological variables, and sex. Pain Med. 2014a;15(4):692–701. doi:10.1111/pme.12312
   PubMed Web of Science ®Google Scholar
• Bjekić J, Živanović M, Purić D, Oosterman JM, Filipović SR. Pain and executive functions: a unique relationship between Stroop task and experimentally induced pain. Psychol Res. 2018;82(3):580–589. doi:10.1007/s00426-016-0838-2
   PubMed Web of Science ®Google Scholar
• Berryman C, Stanton TR, Bowering KJ, Tabor A, McFarlane A, Moseley GL. Do people with chronic pain have impaired executive function? A meta-analytical review. Clin Psychol Rev. 2014;34(7):563–579. doi:10.1016/j.cpr.2014.08.003
   PubMed Web of Science ®Google Scholar
• Staud R. Abnormal endogenous pain modulation is a shared characteristic of many chronic pain conditions. Expert Rev Neurother. 2012;12(5):577–585. doi:10.1586/ern.12.41
   PubMed Web of Science ®Google Scholar
• MacPherson SE, Phillips LH, Della Sala S. Age, executive function and social decision making: a dorsolateral prefrontal theory of cognitive aging. Psychol Aging. 2002;17(4):598–609. doi:10.1037/0882-7974.17.4.598
   PubMed Web of Science ®Google Scholar
• Hermans L, van Oosterwijck J, Goubert D, et al. Inventory of personal factors influencing conditioned pain modulation in healthy people: a systematic literature review. Pain Pract. 2016;16(6):758–769. doi:10.1111/papr.12305
   PubMed Web of Science ®Google Scholar
• Verhoeven K, van Damme S, Eccleston C, van Ryckeghem DML, Legrain V, Crombez G. Distraction from pain and executive functioning: an experimental investigation of the role of inhibition, task switching and working memory. Eur J Pain. 2011;15(8):866–873. doi:10.1016/j.ejpain.2011.01.009
   PubMed Web of Science ®Google Scholar
• Buhle JT, Wager TD. Performance-dependent inhibition of pain by an executive working memory task. Pain. 2010;149(1):19–26. doi:10.1016/j.pain.2009.10.027
   PubMed Web of Science ®Google Scholar
• Marouf R, Caron S, Lussier M, Bherer L, Piché M, Rainville P. Reduced pain inhibition is associated with reduced cognitive inhibition in healthy aging. Pain. 2014;155(3):494–502. doi:10.1016/j.pain.2013.11.011
   PubMed Web of Science ®Google Scholar
• Miyake A, Friedman NP. The nature and organization of individual differences in executive functions: four general conclusions. Curr Dir Psychol Sci. 2012;21(1):8–14. doi:10.1177/0963721411429458
   PubMed Web of Science ®Google Scholar
• Aron AR. The neural basis of inhibition in cognitive control. Neuroscientist. 2007;13(3):214–228. doi:10.1177/1073858407299288
   PubMed Web of Science ®Google Scholar
• Bari A, Robbins TW. Inhibition and impulsivity: behavioral and neural basis of response control. Prog Neurobiol. 2013;108:44–79. doi:10.1016/j.pneurobio.2013.06.005
   PubMed Web of Science ®Google Scholar
• Snyder HR, Miyake A, Hankin BL. Advancing understanding of executive function impairments and psychopathology: bridging the gap between clinical and cognitive approaches. Front Psychol. 2015;6:328. doi:10.3389/fpsyg.2015.00328
   PubMed Web of Science ®Google Scholar
• Friedman NP, Miyake A. Unity and diversity of executive functions: individual differences as a window on cognitive structure. Cortex. 2017;86:186–204. doi:10.1016/j.cortex.2016.04.023
   PubMed Web of Science ®Google Scholar
• Garavan H, Hester R, Murphy K, Fassbender C, Kelly C. Individual differences in the functional neuroanatomy of inhibitory control. Brain Res. 2006;1105(1):130–142. doi:10.1016/j.brainres.2006.03.029
   Web of Science ®Google Scholar
• Matzke D, Verbruggen F, Logan GD. The stop-signal paradigm. In: Wixted JT, Stevens SS, editors. Stevens’ Handbook of Experimental Psychology and Cognitive Neuroscience. Vol. 6, Fourth. New York: John Wiley & Sons, Inc;2018:1–45
   Google Scholar
• Hedge C, Powell G, Sumner P. The reliability paradox: why robust cognitive tasks do not produce reliable individual differences. Behav Res Methods. 2018;50(3):1166–1186. doi:10.3758/s13428-017-0935-1
   PubMed Web of Science ®Google Scholar
• Oosterman JM, Dijkerman HC, Kessels RPC, Scherder EJA. A unique association between cognitive inhibition and pain sensitivity in healthy participants. Eur J Pain. 2010;14(10):1046–1050. doi:10.1016/j.ejpain.2010.04.004
   PubMed Web of Science ®Google Scholar
• Coppieters I, Ickmans K, Cagnie B, et al. Cognitive performance is related to central sensitization and health-related quality of life in patients with chronic whiplash-associated disorders and fibromyalgia. Pain Physician. 2015;18(3):E389–401.
   PubMed Web of Science ®Google Scholar
• Valet M, Sprenger T, Boecker H, et al. Distraction modulates connectivity of the cingulo-frontal cortex and the midbrain during pain–an fMRI analysis. Pain. 2004;109(3):399–408. doi:10.1016/j.pain.2004.02.033
   PubMed Web of Science ®Google Scholar
• Knudsen L, Petersen GL, Nørskov KN, et al. Review of neuroimaging studies related to pain modulation. Scand J Pain. 2018;2(3):108–120. doi:10.1016/j.sjpain.2011.05.005
   Google Scholar
• Bantick SJ, Wise RG, Ploghaus A, Clare S, Smith SM, Tracey I. Imaging how attention modulates pain in humans using functional MRI. Brain. 2002;125(2):310–319. doi:10.1093/brain/awf022
   PubMed Web of Science ®Google Scholar
• Scheef L, Jankowski J, Daamen M, et al. An fMRI study on the acute effects of exercise on pain processing in trained athletes. Pain. 2012;153(8):1702–1714. doi:10.1016/j.pain.2012.05.008
   PubMed Web of Science ®Google Scholar
• Black GAR, Renfroe JB, Hight RE. The effects of caffeine ingestion on exercise-induced hypoalgesia: a pilot study. Physiol Behav. 2016b;161:1–6. doi:10.1016/j.physbeh.2016.04.005
   Web of Science ®Google Scholar
• Verbruggen F, Logan GD. Response inhibition in the stop-signal paradigm. Trends Cogn Sci. 2008;12(11):418–424. doi:10.1016/j.tics.2008.07.005
   PubMed Web of Science ®Google Scholar
• Vaegter HB, Handberg G, Graven-Nielsen T. Similarities between exercise-induced hypoalgesia and conditioned pain modulation in humans. Pain. 2014a;155(1):158–167. doi:10.1016/j.pain.2013.09.023
   PubMed Web of Science ®Google Scholar
• Kleiner M, Brainard DH, Pelli D, Ingling A, Murray R, Broussard C. What’s new in psychtoolbox-3. Perception. 2007;36(4):1–16.
   Google Scholar
• Verbruggen F, Chambers CD, Logan GD. Fictitious inhibitory differences: how skewness and slowing distort the estimation of stopping latencies. Psychol Sci. 2013;24(3):352–362. doi:10.1177/0956797612457390
   PubMed Web of Science ®Google Scholar
• Cathcart S, Pritchard D. Reliability of pain threshold measurement in young adults. J Headache Pain. 2006;7(1):21–26. doi:10.1007/s10194-006-0265-7
   PubMedGoogle Scholar
• Vaegter HB, Handberg G, Graven-Nielsen T. Isometric exercises reduce temporal summation of pressure pain in humans. Eur J Pain. 2014b;19(7):973–983. doi:10.1002/ejp.623
   Web of Science ®Google Scholar
• Vaegter HB, Handberg G, Jorgensen MN, Kinly A, Graven-Nielsen T. Aerobic exercise and cold pressor test induce hypoalgesia in active and inactive men and women. Pain Med. 2015;16(5):923–933. doi:10.1111/pme.12641
   PubMed Web of Science ®Google Scholar
• Swain DP, Abernathy KS, Smith CS, Lee SJ, Bunn SA. Target heart rates for the development of cardiorespiratory fitness. Med Sci Sports Exerc. 1994;26(1):112–116. doi:10.1249/00005768-199401000-00019
   PubMed Web of Science ®Google Scholar
• Borg GA. Psychophysical bases of perceived exertion. Med Sci Sports Exerc. 1982;14(5):377–381. doi:10.1249/00005768-198205000-00012
   PubMed Web of Science ®Google Scholar
• R Core Team. R: A Language and Environment for Statistical Computing. Vienna, Austria: R Foundation for Statistical Computing; 2013. Available from: http://www.R-project.org/. Accessed April 14, 2020.
   Google Scholar
• Verbruggen F, Aron AR, Band GP, et al. A consensus guide to capturing the ability to inhibit actions and impulsive behaviors in the stop-signal task. Elife. 2019;8. doi:10.7554/eLife.46323
   Web of Science ®Google Scholar
• Leys C, Ley C, Klein O, Bernard P, Licata L. Detecting outliers: do not use standard deviation around the mean, use absolute deviation around the median. J Exp Soc Psychol. 2013;49(4):764–766. doi:10.1016/j.jesp.2013.03.013
   Web of Science ®Google Scholar
• Congdon E, Mumford JA, Cohen JR, Galvan A, Canli T, Poldrack RA. Measurement and reliability of response inhibition. Front Psychol. 2012;3:37. doi:10.3389/fpsyg.2012.00037
   PubMed Web of Science ®Google Scholar
• Cohen JL. Statistical Power Analysis for the Behavioral Sciences. Hillsday, NJ: Erlbaum; 1988.
   Google Scholar
• Karsdorp PA, Geenen R, Vlaeyen JWS. Response inhibition predicts painful task duration and performance in healthy individuals performing a cold pressor task in a motivational context. Eur J Pain. 2014;18(1):92–100. doi:10.1002/j.1532-2149.2013.00348.x
   PubMed Web of Science ®Google Scholar
• Zhou S, Kemp J, Després O, Pebayle T, Dufour A. The association between inhibition and pain tolerance in the elderly: evidence from event-related potentials. Eur J Pain. 2015;19(5):669–676. doi:10.1002/ejp.588
   PubMed Web of Science ®Google Scholar
• Hofmann W, Schmeichel BJ, Baddeley AD. Executive functions and self-regulation. Trends Cogn Sci. 2012;16(3):174–180. doi:10.1016/j.tics.2012.01.006
   PubMed Web of Science ®Google Scholar
• Ochsner KN, Gross JJ. The cognitive control of emotion. Trends Cogn Sci. 2005;9(5):242–249. doi:10.1016/j.tics.2005.03.010
   PubMed Web of Science ®Google Scholar
• Solberg Nes L, Roach AR, Segerstrom SC. Executive functions, self-regulation, and chronic pain: a review. Ann Behav Med. 2009;37(2):173–183. doi:10.1007/s12160-009-9096-5
   PubMed Web of Science ®Google Scholar
• van Ryckeghem DM, van Damme S, Eccleston C, Crombez G. The efficacy of attentional distraction and sensory monitoring in chronic pain patients: a meta-analysis. Clin Psychol Rev. 2018;59:16–29. doi:10.1016/j.cpr.2017.10.008
   PubMed Web of Science ®Google Scholar
• Nijs J, Kosek E, van Oosterwijck J, Meeus M. Dysfunctional endogenous analgesia during exercise in patients with chronic pain: to exercise or not to exercise? Pain Physician. 2012;15(3 Suppl):ES205–13.
   PubMed Web of Science ®Google Scholar
• Micalos PS. Perspectives on biochemical and neurosensory mechanisms for exercise-induced pain inhibition. Fatigue. 2014;2(4):219–230. doi:10.1080/21641846.2014.957484
   Google Scholar
• Kosek E, Lundberg L. Segmental and plurisegmental modulation of pressure pain thresholds during static muscle contractions in healthy individuals. Eur J Pain. 2003;7(3):251–258. doi:10.1016/S1090-3801(02)00124-6
   PubMed Web of Science ®Google Scholar
• Lannersten L, Kosek E. Dysfunction of endogenous pain inhibition during exercise with painful muscles in patients with shoulder myalgia and fibromyalgia. Pain. 2010;151(1):77–86. doi:10.1016/j.pain.2010.06.021
   PubMed Web of Science ®Google Scholar
• Tour J, Lofgren M, Mannerkorpi K, et al. Gene-to-gene interactions regulate endogenous pain modulation in fibromyalgia patients and healthy controls-antagonistic effects between opioid and serotonin-related genes. Pain. 2017;158(7):1194–1203. doi:10.1097/j.pain.0000000000000896
   Web of Science ®Google Scholar
• Koltyn KF. Exercise-induced hypoalgesia and intensity of exercise. Sports Med. 2002;32(8):477–487. doi:10.2165/00007256-200232080-00001
   PubMed Web of Science ®Google Scholar
• Alsouhibani A, Hrdina E, Krajewski R, Chirayil A, Stolzman S, Bement MH. (465) Exercise-induced hypoalgesia following six minute walk test. J Pain. 2016;17(4):S90–S90. doi:10.1016/j.jpain.2016.01.442
   Web of Science ®Google Scholar
• Ellingson LD, Cook DB. The hypoalgesic effects of exercise: characteristics, mechanisms and implications for chronic pain. In: Graven-Nielsen T, Arendt-Nielsen L, editors. Musculoskeletal Pain: Basic Mechanisms and Implications. Washington, DC: IASP Press; 2014:471–487.
   Google Scholar
• Cathcart S, Winefield AH, Rolan P, Lushington K. Reliability of temporal summation and diffuse noxious inhibitory control. Pain Res Manag. 2009;14(6):433–438.
   PubMed Web of Science ®Google Scholar
• Houben K, Jansen A. Chocolate equals stop: chocolate-specific inhibition training reduces chocolate intake and go associations with chocolate. Appetite. 2015;87:318–323. doi:10.1016/j.appet.2015.01.005
   PubMed Web of Science ®Google Scholar
• Gallant SN. Mindfulness meditation practice and executive functioning: breaking down the benefit. Conscious Cogn. 2016;40:116–130. doi:10.1016/j.concog.2016.01.005
   PubMed Web of Science ®Google Scholar
• Gomolka S, Vaegter HB, Nijs J, et al. Assessing endogenous pain inhibition: test-retest reliability of exercise-induced hypoalgesia in local and remote body parts after aerobic cycling. Pain Med. 2019;20(11):2272–2282. doi:10.1093/pm/pnz131
   PubMed Web of Science ®Google Scholar
• Vaegter HB, Dorge DB, Schmidt KS, Jensen AH, Graven-Nielsen T. Test-retest reliability of exercise-induced hypoalgesia after aerobic exercise. Pain Med. 2018a;19(11):2212–2222. doi:10.1093/pm/pny009
   PubMed Web of Science ®Google Scholar
• Heathcote A, Lin Y-S, Reynolds A, Strickland L, Gretton M, Matzke D. Dynamic models of choice. Behav Res Methods. 2019;51(2):961–985. doi:10.3758/s13428-018-1067-y
   Web of Science ®Google Scholar