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ORIGINAL RESEARCH

Acupotomy Improves Synovial Hypoxia, Synovitis and Angiogenesis in KOA Rabbits

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Pages 749-760 | Received 02 Dec 2022, Accepted 21 Feb 2023, Published online: 08 Mar 2023

References

  • Vos T, Allen C, Arora M, et al. Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015. Lancet. 2016;388(10053):1545–1602. doi:10.1016/S0140-6736(16)31678-6
  • Ma L, Zheng X, Lin R, et al. Knee osteoarthritis therapy: recent advances in intra-articular drug delivery systems. Drug Des Devel Ther. 2022;16:1311–1347.
  • Mobasheri A, Batt M. An update on the pathophysiology of osteoarthritis. Ann Phys Rehabil Med. 2016;59(5–6):333–339. doi:10.1016/j.rehab.2016.07.004
  • Wei J, Liu L, Li Z, et al. Fire needling acupuncture suppresses cartilage damage by mediating macrophage polarization in mice with knee osteoarthritis. J Pain Res. 2022;15:1071–1082. doi:10.2147/JPR.S360555
  • Mapp PI, Walsh DA. Mechanisms and targets of angiogenesis and nerve growth in osteoarthritis. Nat Rev Rheumatol. 2012;8(7):390–398. doi:10.1038/nrrheum.2012.80
  • Bolia IK, Mertz K, Faye E, et al. Cross-communication between knee osteoarthritis and fibrosis: molecular pathways and key molecules. Open Access J Sports Med. 2022;13:1–15. doi:10.2147/OAJSM.S321139
  • Ashraf S, Walsh DA. Angiogenesis in osteoarthritis. Curr Opin Rheumatol. 2008;20(5):573–580. doi:10.1097/BOR.0b013e3283103d12
  • Robinson WH, Lepus CM, Wang Q, et al. Low-grade inflammation as a key mediator of the pathogenesis of osteoarthritis. Nat Rev Rheumatol. 2016;12(10):580–592. doi:10.1038/nrrheum.2016.136
  • Olivotto E, Trisolino G, Belluzzi E, et al. Macroscopic synovial inflammation correlates with symptoms and cartilage lesions in patients undergoing arthroscopic partial meniscectomy: a clinical study. J Clin Med. 2022;11(15):4330. doi:10.3390/jcm11154330
  • Bonnet CS, Walsh DA. Osteoarthritis, angiogenesis and inflammation. Rheumatology. 2005;44(1):7–16. doi:10.1093/rheumatology/keh344
  • MacDonald IJ, Liu SC, Su CM, Wang YH, Tsai CH, Tang CH. Implications of Angiogenesis Involvement in Arthritis. Int J Mol Sci. 2018;19(7):2012. doi:10.3390/ijms19072012
  • Wang YH, Kuo SJ, Liu SC, et al. Apelin affects the progression of osteoarthritis by regulating VEGF-dependent angiogenesis and miR-150-5p expression in human synovial fibroblasts. Cells-Basel. 2020;9(3):594.
  • Cummins EP, Keogh CE, Crean D, Taylor CT. The role of HIF in immunity and inflammation. Mol Aspects Med. 2016;47–48:24–34. doi:10.1016/j.mam.2015.12.004
  • Stevens CR, Blake DR, Merry P, Revell PA, Levick JR. A comparative study by morphometry of the microvasculature in normal and rheumatoid synovium. Arthritis Rheum. 1991;34(12):1508–1513. doi:10.1002/art.1780341206
  • Ke Q, Costa M. Hypoxia-inducible factor-1 (HIF-1). Mol Pharmacol. 2006;70(5):1469–1480. doi:10.1124/mol.106.027029
  • Hu Y, Zhang T, Chen J, et al. Downregulation of hypoxia-inducible factor-1alpha by RNA interference alleviates the development of collagen-induced arthritis in rats. Mol Ther Nucleic Acids. 2020;19:1330–1342. doi:10.1016/j.omtn.2020.01.014
  • Doria AS, Wang C, Zhong A, et al. Reliability and convergent validity of different BOLD MRI frameworks for data acquisition in experimental arthritis. Acad Radiol. 2011;18(5):615–625. doi:10.1016/j.acra.2010.12.008
  • Prisman E, Slessarev M, Han J, et al. Comparison of the effects of independently-controlled end-tidal PCO(2) and PO(2) on blood oxygen level-dependent (BOLD) MRI. J Magn Reson Imaging. 2008;27(1):185–191. doi:10.1002/jmri.21102
  • Niles DJ, Gordon JW, Fain SB. Effect of anesthesia on renal R2 * measured by blood oxygen level-dependent MRI. NMR Biomed. 2015;28(7):811–817. doi:10.1002/nbm.3314
  • Geborek P, Forslind K, Wollheim FA. Direct assessment of synovial blood flow and its relation to induced hydrostatic pressure changes. Ann Rheum Dis. 1989;48(4):281–286. doi:10.1136/ard.48.4.281
  • Rutherford DJ. Intra-articular pressures and joint mechanics: should we pay attention to effusion in knee osteoarthritis? Med Hypotheses. 2014;83(3):292–295. doi:10.1016/j.mehy.2014.05.021
  • Edmonds SE, Blake DR, Morris CJ, Winyard PG. An imaginative approach to synovitis--the role of hypoxic reperfusion damage in arthritis. J Rheumatol Suppl. 1993;37:26–31.
  • Liu SC, Chuang SM, Hsu CJ, Tsai CH, Wang SW, Tang CH. CTGF increases vascular endothelial growth factor-dependent angiogenesis in human synovial fibroblasts by increasing miR-210 expression. Cell Death Dis. 2014;5:e1485. doi:10.1038/cddis.2014.453
  • Hu F, Mu R, Zhu J, et al. Hypoxia and hypoxia-inducible factor-1alpha provoke toll-like receptor signalling-induced inflammation in rheumatoid arthritis. Ann Rheum Dis. 2014;73(5):928–936. doi:10.1136/annrheumdis-2012-202444
  • Li SM, Li TL, Guo R, et al. Effectiveness and safety of acupotomy for knee osteoarthritis: study protocol for a randomized controlled trial. Trials. 2021;22(1):824. doi:10.1186/s13063-021-05786-5
  • Zhang R, Li L, Chen B, et al. Acupotomy versus nonsteroidal anti-inflammatory drugs for knee osteoarthritis: protocol for a systematic review and meta-analysis. Medicine. 2019;98(36):e17051. doi:10.1097/MD.0000000000017051
  • Felson DT. Osteoarthritis as a disease of mechanics. Osteoarthritis Cartilage. 2013;21(1):10–15. doi:10.1016/j.joca.2012.09.012
  • Ma SN, Xie ZG, Guo Y, et al. Effect of acupotomy on FAK-PI3K signaling pathways in KOA rabbit articular cartilages. Evid Based Complement Alternat Med. 2017;2017:4535326. doi:10.1155/2017/4535326
  • Zhang W, Gao Y, Guo C, Ibrahim ZAK, Farid M. Effect of acupotomy versus electroacupuncture on ethology and morphology in a rabbit model of knee osteoarthritis. J Tradit Chin Med. 2019;39(2):229–236.
  • Taylor NJ, Baddeley H, Goodchild KA, et al. BOLD MRI of human tumor oxygenation during carbogen breathing. J Magn Reson Imaging. 2001;14(2):156–163. doi:10.1002/jmri.1166
  • Shi X, Yu W, Wang T, et al. Electroacupuncture alleviates cartilage degradation: improvement in cartilage biomechanics via pain relief and potentiation of muscle function in a rabbit model of knee osteoarthritis. Biomed Pharmacother. 2020;123:109724. doi:10.1016/j.biopha.2019.109724
  • Wang T, Guo Y, Shi XW, et al. Acupotomy contributes to suppressing subchondral bone resorption in KOA rabbits by regulating the OPG/RANKL signaling pathway. Evid Based Complement Alternat Med. 2021;2021:8168657. doi:10.1155/2021/8168657
  • Ashford S, Williard J. Osteoarthritis: a review. Nurse Pract. 2014;39(5):1–8. doi:10.1097/01.NPR.0000445886.71205.c4
  • Mathiessen A, Conaghan PG. Synovitis in osteoarthritis: current understanding with therapeutic implications. Arthritis Res Ther. 2017;19(1):18. doi:10.1186/s13075-017-1229-9
  • Forkel P, Herbort M, Schulze M, et al. Biomechanical consequences of a posterior root tear of the lateral meniscus: stabilizing effect of the meniscofemoral ligament. Arch Orthop Trauma Surg. 2013;133(5):621–626. doi:10.1007/s00402-013-1716-7
  • Stegen S, Laperre K, Eelen G, et al. HIF-1alpha metabolically controls collagen synthesis and modification in chondrocytes. Nature. 2019;565(7740):511–515. doi:10.1038/s41586-019-0874-3
  • Nagatomo F, Gu N, Fujino H, et al. Effects of exposure to hyperbaric oxygen on oxidative stress in rats with type II collagen-induced arthritis. Clin Exp Med. 2010;10(1):7–13. doi:10.1007/s10238-009-0064-y
  • Nasui OC, Chan MW, Nathanael G, et al. Physiologic characterization of inflammatory arthritis in a rabbit model with BOLD and DCE MRI at 1.5 Tesla. Eur Radiol. 2014;24(11):2766–2778. doi:10.1007/s00330-014-3331-6
  • Macchi V, Stocco E, Stecco C, et al. The infrapatellar fat pad and the synovial membrane: an anatomo-functional unit. J Anat. 2018;233(2):146–154. doi:10.1111/joa.12820
  • Semenza GL. Hypoxia-inducible factors in physiology and medicine. Cell. 2012;148(3):399–408. doi:10.1016/j.cell.2012.01.021
  • Pfander D, Cramer T, Swoboda B. Hypoxia and HIF-1alpha in osteoarthritis. Int Orthop. 2005;29(1):6–9. doi:10.1007/s00264-004-0618-2
  • Konisti S, Kiriakidis S, Paleolog EM. Hypoxia--a key regulator of angiogenesis and inflammation in rheumatoid arthritis. Nat Rev Rheumatol. 2012;8(3):153–162. doi:10.1038/nrrheum.2011.205
  • Ko JY, Lee MS, Lian WS, et al. MicroRNA-29a counteracts synovitis in knee osteoarthritis pathogenesis by targeting VEGF. Sci Rep. 2017;7(1):3584. doi:10.1038/s41598-017-03616-w
  • Song C, Xu X, Wu Y, Ji B, Zhou X, Qin L. Study of the mechanism underlying hsa-miR338-3p downregulation to promote fibrosis of the synovial tissue in osteoarthritis patients. Mol Biol Rep. 2019;46(1):627–637. doi:10.1007/s11033-018-4518-8
  • Xu J, Feng Z, Chen S, et al. Taxol alleviates collagen-induced arthritis in mice by inhibiting the formation of microvessels. Clin Rheumatol. 2019;38(1):19–27. doi:10.1007/s10067-017-3646-1
  • Luo Q, Fan S, Li R, Ouyang Z, Liu Z, Lin Q. Effects of ultrasound on vascular endothelial growth factor in cartilage, synovial fluid, and synovium in rabbit knee osteoarthritis. Acta Biochim Pol. 2020;67(3):379–385. doi:10.18388/abp.2020_5238
  • Qing L, Lei P, Liu H, et al. Expression of hypoxia-inducible factor-1alpha in synovial fluid and articular cartilage is associated with disease severity in knee osteoarthritis. Exp Ther Med. 2017;13(1):63–68. doi:10.3892/etm.2016.3940
  • Li Y, Liu Y, Wang C, et al. Succinate induces synovial angiogenesis in rheumatoid arthritis through metabolic remodeling and HIF-1alpha/VEGF axis. Free Radic Biol Med. 2018;126:1–14. doi:10.1016/j.freeradbiomed.2018.07.009
  • Zhang L, Zhang L, Huang Z, et al. Increased HIF-1alpha in knee osteoarthritis aggravate synovial fibrosis via fibroblast-like synoviocyte pyroptosis. Oxid Med Cell Longev. 2019;2019:6326517. doi:10.1155/2019/6326517
  • Quinonez-Flores CM, Gonzalez-Chavez SA, Pacheco-Tena C. Hypoxia and its implications in rheumatoid arthritis. J Biomed Sci. 2016;23(1):62. doi:10.1186/s12929-016-0281-0
  • Zhang H, Ding L, Shi X, et al. Imperatorin alleviated NLR family pyrin domain-containing 3 inflammasome cascade-induced synovial fibrosis and synovitis in rats with knee osteoarthritis. Bioengineered. 2021;12(2):12954–12964. doi:10.1080/21655979.2021.2012949
  • Zhu J, Su C, Chen Y, Hao X, Jiang J. Electroacupuncture on ST36 and GB39 acupoints inhibits synovial angiogenesis via downregulating HIF-1alpha/VEGF expression in a rat model of adjuvant arthritis. Evid Based Complement Alternat Med. 2019;2019:5741931. doi:10.1155/2019/5741931
  • Liu SC, Tsai CH, Wang YH, et al. Melatonin abolished proinflammatory factor expression and antagonized osteoarthritis progression in vivo. Cell Death Dis. 2022;13(3):215. doi:10.1038/s41419-022-04656-5
  • Li X, Mei W, Huang Z, et al. Casticin suppresses monoiodoacetic acid-induced knee osteoarthritis through inhibiting HIF-1alpha/NLRP3 inflammasome signaling. Int Immunopharmacol. 2020;86:106745. doi:10.1016/j.intimp.2020.106745
  • Niendorf T, Pohlmann A, Arakelyan K, et al. How bold is blood oxygenation level-dependent (BOLD) magnetic resonance imaging of the kidney? Opportunities, challenges and future directions. Acta Physiol. 2015;213(1):19–38. doi:10.1111/apha.12393
  • Rakow-Penner R, Daniel B, Glover GH. Detecting blood oxygen level-dependent (BOLD) contrast in the breast. J Magn Reson Imaging. 2010;32(1):120–129. doi:10.1002/jmri.22227
  • McPhail LD, Robinson SP. Intrinsic susceptibility MR imaging of chemically induced rat mammary tumors: relationship to histologic assessment of hypoxia and fibrosis. Radiology. 2010;254(1):110–118. doi:10.1148/radiol.2541090395
  • Liu M, Guo X, Wang S, et al. BOLD-MRI of breast invasive ductal carcinoma: correlation of R2* value and the expression of HIF-1alpha. Eur Radiol. 2013;23(12):3221–3227. doi:10.1007/s00330-013-2937-4
  • Chan MW, Nathanael G, Kis A, et al. Systematic protocol for assessment of the validity of BOLD MRI in a rabbit model of inflammatory arthritis at 1.5 tesla. Pediatr Radiol. 2014;44(5):566–575. doi:10.1007/s00247-013-2844-5