GIRK2 and neuronal pattern of generation and settling in homozygous weaver mice

References

• Jan LY, Jan YN. Cloned potassium channels from eukaryotes and prokaryotes. Annu RevNeurosci. 1997;20:91–123.
   PubMed Web of Science ®Google Scholar
• Harkins AB, Fox AP. Cell death in weaver cerebellum. The Cerebellum. 2002;1:201–206.
   Google Scholar
• Sadja R, Alagem N, Reuveny E. Gating of GIRK channels: details of an intrincate membrane-delimited signaling complex. Neuron. 2003;39:9–12.
   Web of Science ®Google Scholar
• Stanfield PR, Nakajima S, Nakajima Y. Constitutively active and G-protein coupled inward rectifier K+ channels: Kir2.0 and Kir3.0. Rev PhysiolBiochem Pharmacol 2002;145:47–179.
   Web of Science ®Google Scholar
• Kobayashi T, Ikeda K, Ichikawa T, Abe S, Togashi S, Kumanishi T. Molecular cloning of a mouse G-protein-activated K+ channel (mGIRK1) and distinct distributions of three GIRK (GIRK1, 2 and 3) mRNAs in mouse brain. Biochem Biophys Res Commun. 1995;208:1166–1173.
   PubMed Web of Science ®Google Scholar
• Krapivinsky G, Gordon EA, Wickman K, Velimirovic B, Krapivinsky L, Clapham DE. The G-protein-gated atrial K+ channel IKACh is a heteromultimer of two inwardly rectifying K+ channel proteins. Nature. 1995;374:135–141.
   PubMed Web of Science ®Google Scholar
• Wickman K, Karschin C, Karschin A, Picciotto MR, Clapham DE. Brain localization and behavioral impact of the G-protein-gated K+ channel subunit GIRK4. J Neurosci. 2000;20:5608–5615.
   PubMed Web of Science ®Google Scholar
• Lesage F, Guillemare E, Fink M, et al. Molecular properties of neuronal G-protein-activated inwardly rectifying K+ channels. J Biol Chem. 1995;270:28660–28667.
   Web of Science ®Google Scholar
• Liao YJ, Jan YN, Jan LY. Heteromultimerization of G-protein-gated inwardly rectifying K+ channel proteins GIRK1 and GIRK2 and their altered expression in weaver brain. J Neurosci. 1996;16:7137–7150.
   Web of Science ®Google Scholar
• Inanobe A, Yoshimoto Y, Horio Y, et al. Characterization of G-protein-gated K+ channels composed of Kir3. 2 subunits in dopaminergic neurons of the substantia nigra. J Neurosci. 1999;19:1006–1017.
   Web of Science ®Google Scholar
• Kofuji P Davidson N, Lester HA. Evidence that neuronal G-protein-gated inwardly rectifying K+ channels are activated by G beta gamma subunits and function as heteromultimers. Proc Natl Acad Sci U S A. 1995;92:6542–6546.
   PubMed Web of Science ®Google Scholar
• Ma D, Zerangue N, Raab-Graham K, Fried SR, Jan YN, Jan LY. Diverse trafficking patterns due to multiple traffic motifs in G protein-activated inwardly rectifying potassium channels from brain and heart. Neuron. 2002;33:715–729.
   PubMed Web of Science ®Google Scholar
• Jelacic TM, Kennedy ME, Wickman K, Clapham DE. Functional and biochemical evidence for G-protein-gated inwardly rectifying K+ (GIRK) channels composed of GIRK2 and GIRK3. J Biol Chem. 2000;275:36122–36216.
   Web of Science ®Google Scholar
• Cheng SV Nadeau JH, Tanzi RE, et al. Comparative mapping of DNA markers from familial Alzheimer disease and Down syndrome regions of human chromosome 21 to mouse chromosomes 16 and 17. Proc Natl Acad Sci US A. 1988;85:6032–6036.
   Web of Science ®Google Scholar
• Reeves RH, Crowley MR, Lorenzon N, Pavan WJ, Smeyne RJ, Goldowitz D. The mouse neurological mutant weaver maps within the region of chromosome 16 that is homologous to human chromosome 21. Genomics. 1989;5:522–526.
   PubMed Web of Science ®Google Scholar
• Patil N, Cox DR, Bhat D, Faham M, Myers RM, Peterson AS. A potassium channel mutation in weaver mice implicates membrane excitability in granule differentiation. Nature Genet. 1995;11:126–129.
   PubMed Web of Science ®Google Scholar
• Karschin C, Dissman E, Stuhmer W, Karschin A. IRK(1–3) and GIRK(1–4) inwardly rectifiying K+ channel mRNA are differentially expressed in the adult rat brain. J Neurosci. 1996;16:3559–3570.
   PubMed Web of Science ®Google Scholar
• Wei J, Dlouhy SR, Bayer S, et al. In situ hybridization analysis of Girk2 expression in the developing central nervous system in normal and weaver mice. J Neuropathol Exp Neurol. 1997;56(7):762–771.
   Web of Science ®Google Scholar
• Sekiguchi M, Nowakowski RS, Nagato Y, et al. Morphologial abnormalities in the hippocampus of the weaver mutant mouse. Brain Res. 1995;696:262–267.
   Web of Science ®Google Scholar
• Schein JC, Hunter DD, Roffler-Tarlov S. Girk2 expression in the ventral midbrain, cerebellum, and olfactory bulb and its relationship to the murine mutation weaver. Dev Biol. 1998;204:432–450.
   Web of Science ®Google Scholar
• Savy C, Martin-Martinelli E, Simon A, et al. Altered development of dopaminergic cells in retina of weaver mice. J Comp Neurol. 1999;412:656–668.
   Web of Science ®Google Scholar
• Rezai Z, Yoon CH. Abnormal rate of granule cell migration in the cerebellum of weaver mutant mice. Dev Biol. 1972;29:17–26.
   PubMed Web of Science ®Google Scholar
• Rakic P, Sidman RL. Sequence of developmental abnormalities leading to granule cell deficit in cerebellar cortex of weaver mutant mice. J Comp Neurol 1973;152:103–132.
   PubMed Web of Science ®Google Scholar
• Blatt BJ, Eisenman LM. A quantitative and quantitative light microscopic study of the inferior olivary complex of normal, reeler, and weaver mutant mice. J Comp Neurol. 1985;232:117–128.
   Web of Science ®Google Scholar
• Smeyne RJ, Goldowitz D. Developmental and death of external granular layer cells in the weaver mouse cerebellum: a quantitative study. J Neurosci. 1989;9:1608–1620.
   Web of Science ®Google Scholar
• Marti J, Wills KV, Ghetti B, Bayer SA. Evidence that the loss of Purkinje cells and deep cerebellar nuclei neurons in homozygous weaver is not related to neurogenetic patterns. Int J Devi Neurosci. 2001;19:599–610.
   Web of Science ®Google Scholar
• Goldowitz D, Mullen RJ. Granule cell as a site of gene action in the weaver mouse cerebellum: evidence from heterozygous mutant chimeras. J Neurosci. 1982;2:1474–1485.
   PubMed Web of Science ®Google Scholar
• Herrup K, Trenkner E. Regional differences in cytoarchitecture of the weaver cerebellum suggest a new model for weaver gene action. Neuroscience. 1987;23:871–885.
   Web of Science ®Google Scholar
• Eisenman LM, Gallagher E, Hawkes R. Regionalization defects in the weaver cerebellum. J Comp Neurol. 1998;394:431–444.
   Web of Science ®Google Scholar
• Armstrong C, Hawkes R. Selective Purkinje cell ectopia in the cerebellum of the weaver mouse. J Comp Neurol. 2001;439:151–161.
   Web of Science ®Google Scholar
• Ozaki M, Hashikawa T, Ikeda K, et al. Degeneration of pontine mossy fibers during cerebellar development in weaver mutant mice. Eur J Neurosci. 2002;16:565–574.
   Web of Science ®Google Scholar
• Lalonde R, Strazielle C. Spontaneous and induced mouse mutations with cerebellar dysfunctions: behavior and neurochemistry. Brain Research. 2007;1140:1–74.
   Web of Science ®Google Scholar
• Lane JD, Nadi NS, McBride WJ, Aprison MH, Kusano K. Content of serotonin, norepinephrine and dopamine in the cerebrum of the “staggerer”, “weaver” and “nervous” neurologically mutant mice. J Neurochem. 1977;29:349–350.
   Web of Science ®Google Scholar
• Schmidt MJ, Sawyer BD, Perry KW, Fuller RW, Foreman MM, Ghetti B. Dopamine deficiency in the weaver mutant mouse. J Neurosci. 1982;2:376–380.
   PubMed Web of Science ®Google Scholar
• Triarhou LC, Norton J, Ghetti B. Mesencephalic dopamine cell deficit involves areas A8, A9 and A10 in weaver mutant mice. Exp Brain Res. 1988;70:256–265.
   PubMed Web of Science ®Google Scholar
• Verney C, Febvret-Muzerelle A, Gaspar P. Early postnatal changes of the dopaminergic mesencephalic neurons in the weaver mutant mouse. Dev Brain Res. 1995;89:115–119.
   Google Scholar
• Roffler-Tarlov S, Martin B, Graybiel AM, Kauer JS. Cell death in the midbrain of the murine mutation weaver. J Neurosci. 1996;16:1819–1826.
   Web of Science ®Google Scholar
• Martí J, Wills KW, Ghetti B, Bayer SA. A combined immunohistochemical and autoradiographic method to detect midbrain neurons and determine their time of origin. Brain Res Protoc. 2002;9:197–205.
   Google Scholar
• Martí J, Wills KW, Ghetti B, Bayer SA. Regional differences in the Purkinje cells settled pattern: a comparative autoradiographic study in control and homozygous weaver mice. Exp Neurol. 2002;175:168–181.
   Web of Science ®Google Scholar
• Martí J, Santa-Cruz MC, Bayer SA, Ghetti, B, Hervás, JP Purkinje cell age-distribution in fissures and in foliar crowns: a comparative study in the weaver cerebellum. Brain Struct Funct. 2007;212:347–357.
   Web of Science ®Google Scholar
• Altman J, Bayer SA. Development ofthe cerebellar system in relation to its evolution, structure andfunctions. Boca Raton, FL: CRC Press; 1997.
   Google Scholar
• Lange W. Regional differences in the cytoarchitecture of the cerebellar cortex. In: Palay SL, Chan-Palay V editors. The cerebellum: new vistas. Berlin, Germany: Springer-Verlag; 1982. p. 93–107.
   Google Scholar
• Sidman RL, Angevine JB, Taber-Pierce E. Atlas of the mouse brain and spinal cord. Cambridge, MA: Harvard University Press; 1971.
   Google Scholar
• Bayer SA, Altman J. . Neurogenesis and neuronal migration. In: Patxinos G, editor. The rat nervous system. San Diego, CA: Academic Press; 1995. p. 1041–1078.
   Google Scholar
• Bayer SA, Wills KV, Wei J, et al. Phenotypic effects of the weaver gene are evident in the embryonic cerebellum but not in the ventral midbrain. Dev Brain Research. 1996;96:130–137.
   Web of Science ®Google Scholar
• Martí J, Santa-Cruz MC, Bayer SA, Hervás JP. The weaver gene expression affects neuronal generation patterns depending on age and encephalic region. Neurosci Lett. 2006;396(3):202–206.
   Web of Science ®Google Scholar
• Bayer SA, Wills KV, Triarhou LC, Thomas JD, Ghetti B. Systematic differences in time of dopaminergic neuron origin between normal mice and homozygous weaver mutants. Exp Brain Res. 1995;105:200–208.
   Web of Science ®Google Scholar
• Bayer SA, Wills KV, Triarhou LC, Verina T, Thomas JD, Ghetti B. Selective vulnerability of late-generated dopaminergic neurons of the substantia nigra in weaver mutant mice. Proc Natl Acad U S A. 1995;92:9137–9140.
   Web of Science ®Google Scholar
• Martí J, Wills KW, Ghetti B, Bayer SA. The weaver gene has no effect on the generation patterns of mesencephalic dopamine neurons. Dev Brain Res. 2000;122:65–172.
   Google Scholar
• Martí J, Wills KW, Ghetti B, Bayer SA. The weaver gene continues to target late-generated dopaminergic neurons in midbrain areas at P90. Dev Brain Res. 2000;122:173–181.
   Google Scholar
• Martí J, Santa-Cruz MC, Bayer SA, Ghetti B, Hervás JP. Generation and survival of midbrain dopaminergic neurons in weaver mice. Int J Devl Neurosci. 2007;25(5):299–307.
   Web of Science ®Google Scholar
• Smeyne RJ, Goldowitz D. Purkinje cell loss is due to a direct action of the weaver gene in Purkinje cells: evidence from chimeric mice. Dev Brain Res. 1990;52:211–218.
   Google Scholar
• Maricich SM, Soha J, Trenkner E, Herrup K. Failed cell migration and death of Purkinje cells and deep nuclear neurons in the weaver cerebellum. J Neurosci. 1997;17:675–3683.
   Web of Science ®Google Scholar
• Inouye M, Murakami U. Temporal and spatial patterns of Purkinje cell formation in the mouse cerebellum. J Comp Neurol. 1980;194:499–503.
   PubMed Web of Science ®Google Scholar
• Yuasa S, Kawamura K, Ono K, Yamakumi T, Takahashi T. Development and migration of Purkinje cells in the mouse cerebellar primordium. Anat Embryol. 1991;184:195–212.
   Google Scholar
• Aguado C, Colón J, Ciruela F, et al. Cell type-specific subunit composition of G protein-gated potassium channels in the cerebellum. J Neurochem. 2008;105:497–511.
   PubMed Web of Science ®Google Scholar
• Lauritzen I, De Weille J, Adelbrecht C, et al. Comparative expression of the inward rectifier K+ channel GIRK2 in the cerebellum of normal and weaver mice. Brain Res. 1997;753:8–17.
   Web of Science ®Google Scholar
• Isomoto S, Kondo C, Takahashi N, et al. A novel ubiquitously distributed isoform of GIRK2 (GIRKb) enhances GIRK1 expression of the G-protein-gated K+ current in Xenopus oocytes. Biochem Biophys Res Commun. 1996;218:286–291.
   PubMed Web of Science ®Google Scholar
• Wei J, Hodes ME, Piva R, et al. Characterization of murine Girk2 transcript isoforms: structure and differentiatial expression. Genomics. 1998;51:379–390.
   PubMed Web of Science ®Google Scholar
• Slesinger PA, Patil N, Liao YJ, Jan YN, Jan LY, Cox DR. Functional effects of the mouse weaver mutation on G protein-gated inwardly rectifying K+ channels. Neuron. 1996;16:321–331.
   PubMed Web of Science ®Google Scholar
• Schoots O, Wilson JM, Ethier N, Bigras E, Hebert TE, Van Tol HH. Co-expression of human Kir3 subunits can yield channels with different functional properties. Cell Signal. 1999;11:871–883.
   PubMed Web of Science ®Google Scholar
• Koyrakh L, Lujan R, Colón J, et al. Molecular and cellular diversity of neuronal G-protein-gated potassium channels. J Neurosci. 2005;25:11468–11478.
   PubMed Web of Science ®Google Scholar
• Tucker SJ, Pessia M, Moorhouse AJ, et al. Heteromeric channel formation and Ca2+ -free media reduce the toxic effect of the weaver Kir 3.2 allele. FEBS Lett. 1996;390:253–257.
   Web of Science ®Google Scholar
• Chen SC, Ehrhard P, Goldowitz D, Smeyne RJ. Developmental expression of the GIRK family of inward rectifying potassium channels: implications for abnormalities in the weaver mutant mouse. Brain Res. 1997;778:251–264.
   Web of Science ®Google Scholar
• Graybiel AM, Ohta K, Roffler-Tarlov S. Patterns of cell and fiber vulnerability in the mesostriatal system of the mutant mouse weaver. I. Gradients and compartments. J Neurosci. 1990;10(3):720–733.
   Web of Science ®Google Scholar
• Harashima C, Jacobowitz DM, Witta J, et al. Abnormal expression of the G-protein activated inwardly rectifying potassium channel 2 (GIRK2) in hippocampus, frontal cortex, and substantia nigra of Ts65Dn mouse: a model of Down syndrome. J Comp Neurol. 2006;494:815–833.
   PubMed Web of Science ®Google Scholar
• Liss B, Neu A, Roeper J. The weaver mouse gain-of-function phenotype of dopaminergic midbrain neurons is determined by coactivation of wwGirk2 and K-ATP channels. J Neurosci. 1999;15:839–8848.
   Google Scholar
• Cruz HG, Ivanova T, Lunn ML, Stoffel M, Slesinger PA, Lüscher C. Bi-directional effects of GABA(B) receptor agonists on the mesolimbic dopamine system. Nat Neurosci. 2004;7:153–159.
   Web of Science ®Google Scholar
• Matzuk MM, Saper CB. Preservation of hypothalamic dopaminergic neurons in Parkinson’s disease. Ann Neurol. 1985;18:552–555.
   Web of Science ®Google Scholar
• Damier P, Hirsch EC, Agid Y, Graybiel AM. The substantia nigra of the human brain II. Patterns of loss of dopamine-containing neurons in Parkinson’s disease. Brain. 1999;122:1437–1448.
   PubMed Web of Science ®Google Scholar
• Kordower JH, Emborg ME, Bloch J, et al. Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson’s disease. Science. 2000;290:767–773.
   PubMed Web of Science ®Google Scholar
• Grondin R, Zhang Z, Yi A, et al. Chronic, controlled GDNF infusion promotes structural and functional recovery in advanced parkinsonian monkeys. Brain. 2002;125:2191–2201.
   PubMed Web of Science ®Google Scholar
• Broome JD, Will KV, Lapchak PA, Ghetti B, Camp LL, Bayer SA. Glial cell line-derived neurotrophic factor protects midbrain dopamine neurons from the lethal action of the weaver gene: a quantitative immunocytochemical study. Dev Brain Res. 1999;116:1–7.
   Google Scholar
• Love S, Plaha P, Patel NK, Hotton GR, Brooks DJ, Gill SS. Glial cell line-derived neurotrophic factor induces neuronal sprouting in human brain. Nat Med. 2005;11:703–704.
   PubMed Web of Science ®Google Scholar