410
Views
22
CrossRef citations to date
0
Altmetric
Original Research

Efficacy and safety of Ginkgo biloba standardized extract in the treatment of vascular cognitive impairment: a randomized, double-blind, placebo-controlled clinical trial

, , , , , & show all
Pages 483-490 | Published online: 16 Feb 2017

References

  • UdeCSchubert-ZsilaveczMWurglicsMGinkgo biloba extracts: a review of the pharmacokinetics of the active ingredientsClin Pharmacokinet201352972774923703577
  • IhlRFrolichLWinbladBSchneiderLBurnsAMollerHJWFSBP Task Force on Treatment Guidelines for Alzheimer’s Disease and other DementiasWorld federation of societies of biological psychiatry (WFSBP) guidelines for the biological treatment of Alzheimer’s disease and other dementiasWorld J Biol Psychiatry201112123221288069
  • YanchevaSIhlRNikolovaGPanayotovPSchlaefkeSHoerrRGINDON Study GroupGinkgo biloba extract EGb 761®, donepezil or both combined in the treatment of Alzheimer’s disease with neuropsychiatric features: a randomised, double-blind, exploratory trialAging Ment Health200913218319019347685
  • ZhangSJXueZYEffect of Western medicine therapy assisted by Ginkgo biloba tablet on vascular cognitive impairment of none dementiaAsian Pac J Trop Med20125866166422840457
  • Orendorz-FraczkowskaKPospiechLGawronWResults of combined treatment for vestibular receptor impairment with physical therapy and Ginkgo biloba extract (Egb 761)Otolaryngol Pol20025618388 Polish12053674
  • SokolovaLHoerrRMishchenkoTTreatment of vertigo: a randomized, double-blind trial comparing efficacy and safety of Ginkgo biloba extract EGb 761 and betahistineInt J Otolaryngol2014201468243925057270
  • MorgensternCBiermannEThe efficacy of Ginkgo special extract EGb 761 in patients with tinnitusInt J Clin Pharmacol Ther200240518819712051570
  • von BoetticherAGinkgo biloba extract in the treatment of tinnitus: a systematic reviewNeuropsychiatr Dis Treat2011744144721857784
  • GavrilovaSIPreussUWWongJWHoerrRKaschelRBachinskayaNGIMCIPlus Study GroupEfficacy and safety of Ginkgo biloba extract EGb 761 in mild cognitive impairment with neuropsychiatric symptoms: a randomized, placebo-controlled, double-blind, multi-center trialInt J Geriatr Psychiatry201429101087109524633934
  • IhlRTribanekMBachinskayaNGOTADAY Study GroupEfficacy and tolerability of a once daily formulation of Ginkgo biloba extract EGb 761® in Alzheimer’s disease and vascular dementia: results from a randomised controlled trialPharmacopsychiatry2012452414622086747
  • TanMSYuJTTanCCEfficacy and adverse effects of Ginkgo biloba for cognitive impairment and dementia: a systematic review and meta-analysisJ Alzheimers Dis201543258960325114079
  • NashKMShahZACurrent perspectives on the beneficial role of Ginkgo biloba in neurological and cerebrovascular disordersIntegr Med Insights2015101926604665
  • CiezaAMaierPPoppelEEffects of Ginkgo biloba on mental functioning in healthy volunteersArch Med Res200334537338114602503
  • PincemailJDupuisMNasrCSuperoxide anion scavenging effect and superoxide dismutase activity of Ginkgo biloba extractExperientia19894587087122547645
  • ClostreFGinkgo biloba extract (EGb 761). State of knowledge in the dawn of the year 2000Ann Pharm Fr199957Suppl 11S81S88 French10481350
  • ChungKFDentGMcCuskerMGuinotPPageCPBarnesPJEffect of a ginkgolide mixture (BN 52063) in antagonising skin and platelet responses to platelet activating factor in manLancet1987185272482512880069
  • HofferberthBThe effect of Ginkgo biloba extract on neurophysiological and psychometric measurement results in patients with psychotic organic brain syndrome. A double-blind study against placeboArzneimittelforschung1989398918922 German2684175
  • Abdel-WahabBAAbd El-AzizSMGinkgo biloba protects against intermittent hypoxia-induced memory deficits and hippocampal DNA damage in ratsPhytomedicine201219544445022265820
  • Hosseini-SharifabadMAnvariMEffects of Ginkgo biloba extract on the structure of Cornu Ammonis in aged rat: a morphometric studyIran J Basic Med Sci201518993293726523225
  • BattistinLCagninAVascular cognitive disorder. A biological and clinical overviewNeurochem Res201035121933193821127967
  • YangTSunYLuZLeakRKZhangFThe impact of cerebrovascular aging on vascular cognitive impairment and dementiaAgeing Res Rev201734152927693240
  • SachdevPKalariaRO’BrienJDiagnostic criteria for vascular cognitive disorders: a VASCOG statementAlzheimer Dis Assoc Disord201428320621824632990
  • KleijnenJKnipschildPGinkgo biloba for cerebral insufficiencyBr J Clin Pharmacol19923443523581457269
  • VellasBColeyNOussetPJGuidAge Study GroupLong-term use of standardised Ginkgo biloba extract for the prevention of Alzheimer’s disease (GuidAge): a randomised placebo-controlled trialLancet Neurol2012111085185922959217
  • SnitzBEO’MearaESCarlsonMCGinkgo Evaluation of Memory (GEM) Study InvestigatorsGinkgo biloba for preventing cognitive decline in older adults: a randomized trialJAMA2009302242663267020040554
  • SchneiderLSGinkgo and AD: key negatives and lessons from Guid-AgeLancet Neurol2012111083683722959218
  • WeinmannSRollSSchwarzbachCVauthCWillichSNEffects of Ginkgo biloba in dementia: systematic review and meta-analysisBMC Geriatr2010101420236541
  • WangBSWangHSongYYEffectiveness of standardized Ginkgo biloba extract on cognitive symptoms of dementia with a six-month treatment: a bivariate random effect meta-analysisPharmacopsychiatry2010433869120104449
  • AmievaHMeillonCHelmerCBarberger-GateauPDartiguesJFGinkgo biloba extract and long-term cognitive decline: a 20-year follow-up population-based studyPLoS One201381e5275523326356
  • IhlREffects of Ginkgo biloba extract EGb 761® in dementia with neuropsychiatric features: review of recently completed randomised, controlled trialsInt J Psychiatry Clin Pract201317Suppl 181423808613
  • BrondinoNDe SilvestriAReSA systematic review and meta-analysis of Ginkgo biloba in neuropsychiatric disorders: from ancient tradition to modern-day medicineEvid Based Complement Alternat Med2013201391569123781271
  • YangGWangYSunJZhangKLiuJGinkgo biloba for mild cognitive impairment and alzheimer’s disease a systematic review and meta-analysis of randomized controlled trialsCurr Top Med Chem201616552052826268332
  • MazzaMCapuanoABriaPMazzaSGinkgo biloba and donepezil: a comparison in the treatment of Alzheimer’s dementia in a randomized placebo-controlled double-blind studyEur J Neurol200613998198516930364
  • KruntoradovaKMandelikovaMMlcochTDolezalTCost-effectiveness analysis of Ginkgo biloba extract (Egb761® – Tanakan®) for the treatment of dementia in the Czech RepublicValue Health2015187A756
  • ZengXLiuMYangYLiYAsplundKGinkgo biloba for acute ischaemic strokeCochrane Database Syst Rev20054CD00369116235335
  • BirksJGrimley EvansJGinkgo biloba for cognitive impairment and dementiaCochrane Database Syst Rev20091CD00312019160216
  • OskoueiDSRikhtegarRHashemilarMThe effect of Ginkgo biloba on functional outcome of patients with acute ischemic stroke: a double-blind, placebo-controlled, randomized clinical trialJ Stroke Cerebrovasc Dis2013228e557e56323871729
  • WangLZhangTBaiKSystem evaluation on Ginkgo biloba extract in the treatment of acute cerebral infarctionZhong Nan Da Xue Xue Bao Yi Xue Ban2015401010961102 Chinese26541843
  • GardnerCDZehnderJLRigbyAJNicholusJRFarquharJWEffect of Ginkgo biloba (EGb 761) and aspirin on platelet aggregation and platelet function analysis among older adults at risk of cardiovascular disease: a randomized clinical trialBlood Coagul Fibrinolysis200718878779317982321
  • HongJMShinDHLimYALeeJSJooISTiclopidine with Ginkgo biloba extract: a feasible combination for patients with acute cerebral ischemiaThromb Res20131314e147e15323477707
  • KullerLHIvesDGFitzpatrickALDoes Ginkgo biloba reduce the risk of cardiovascular events?Circ Cardiovasc Qual Outcomes201031414720123670