Could lysine supplementation prevent Alzheimer’s dementia? A novel hypothesis

Robert N RubeyRetired, Red Lodge, Montana, USACorrespondence[email protected]

Pages 707-710 | Published online: 27 Oct 2010

Cite this article

Full Article
Figures & data
References
Citations
Metrics
Licensing
Reprints & Permissions
View PDF PDF

References

BallMJLimbic predilection in Alzheimer’s dementia: is reactivated herpes virus involved?Can J Neurol Sci1982933033067116237
PubMed Web of Science ®Google Scholar
ItzhakiRFWozniakMAHerpes simplex virus type 1 in Alzheimer’s disease: the enemy withinJ Alzheimers Dis200813439340518487848
PubMed Web of Science ®Google Scholar
Wozniak ShipleySJCombrinckMWilcockGKItzhakiRFProductive herpes simplex virus in brain of elderly normal subjects and Alzheimer’s disease patientsJ Med Virol200575230030615602731
PubMed Web of Science ®Google Scholar
CacquevelMLebeurrierNCheenneSVivienDCytokines in neuroinflammation and Alzheimer’s diseaseCurr Drug Targets20045652953415270199
PubMed Web of Science ®Google Scholar
LokensgardJRHuSShengERobust expression of TNF alpha, IL-1beta, RANTES, and IP-10 by human microglial cells during non-productive infection with herpes simplex virusJ Neurovirol20017320821911517395
PubMed Web of Science ®Google Scholar
CribbsDHAzizehBYCotmanCWLaFerlaFMFibril formation and neurotoxicity by a herpes simplex virus glycoprotein B fragment with homology to the Alzheimer’s A beta peptideBiochemistry200039205988599410821670
PubMed Web of Science ®Google Scholar
Satpute-KrishnanPDeGiorgisJABearerElFast anterograde transport of herpes simplex virus: role for the amyloid precursor protein of Alzheimer’s diseaseAging Cell20032630531814677633
PubMed Web of Science ®Google Scholar
WozniakMAItzhakiRFShipleySJDobsonCBHerpes simplex virus infection causes cellular beta-amyloid accumulation and secretase upregulationNeurosci Lett20074292395100
Web of Science ®Google Scholar
BenettiLRoizmanBHerpes simplex virus proteinkinase US3 activates and functionally overlaps protein kinase A to block apoptosisProc Natl Acad Sci U S A20041019411921615192152
PubMed Web of Science ®Google Scholar
BenderFCWhitbeckJCPonce de LeonMLouHEisenbergRJCohenGHSpecific association of glycoprotein B with lipid rafts during herpes simplex virus entryJ Virol200377179542955212915568
PubMed Web of Science ®Google Scholar
HillJMSteinerIMatthewsKETrahanSGFosterTPBallMJStatins lower the risk of developing Alzheimer’s disease by limiting lipid raft endocytosis and decreasing the neuronal spread of Herpes simplex virus type 1Med Hypotheses2005641535815533611
PubMed Web of Science ®Google Scholar
McGrathNAndersonNECroxsonMCPowellKFHerpes simplex encephalitis treated with acyclovir: diagnosis and long term outcomeJ Neurol Neurosurg Psychiatry19976333213269328248
PubMed Web of Science ®Google Scholar
ItzhakiRFWozniakMAAppeltDMBalinBJInfiltration of the brain by pathogens causes Alzheimer’s diseaseNeurobiol Aging200425561962715172740
PubMed Web of Science ®Google Scholar
LinWRGrahamJMacGowanSMWilcockGKItzhakiRFAlzheimer’s disease, herpes virus in brain, apolioprotein E4, and herpes labialisAlzheimers Rep19981173178
Google Scholar
InglisVBRequirement of arginine for the replication of herpes virusJ Gen Virol1968319174300568
PubMed Web of Science ®Google Scholar
GriffithRSDeLongDCNelsonJDRelation of arginine-lysine antagonism to herpes simplex growth in tissue cultureChemotherapy19812732092136262023
PubMed Web of Science ®Google Scholar
MilmanNScheibelJJessenOFailure of lysine treatment in recurrent herpes simplex labialisLancet19782809694281954
PubMed Web of Science ®Google Scholar
TheinDJHurtWCLysine as a prophylactic agent in the treatment or recurrent herpes simplex labialisOral Surg Oral Med Oral Pathol19845866596666438572
PubMedGoogle Scholar
McCuneMAPerryHOMullerSAO’FallonWMTreatment of recurrent herpes simplex infections with L-lysine monohydrochlorideCutis19843443663736435961
PubMed Web of Science ®Google Scholar
GriffithRSWalshEWMyrmelKHThompsonRWBehforoozASuccess of L-lysine therapy in frequently recurrent herpes simplex infectionDermatologica198717541831903115841
PubMedGoogle Scholar
FernandezJLopezAWangCTranscriptional control of the arginine/lysine transporter, cat-1, by physiological stressJ Biol Chem200327850500005000914523001
PubMed Web of Science ®Google Scholar
MolinaJAJimenez-JimenezFJGomezPDecreased cerebrospinal fluid levels of neutral and basic amino acids in patients with Parkinson’s diseaseJ Neurol Sci199715021231279268238
PubMed Web of Science ®Google Scholar
WakimotoPBlockGDietary intake, dietary patterns, and changes with age: epidemiological perspectiveJ Gerontol A Biol Sci Med Sci200156Spec No 2658011730239
PubMed Web of Science ®Google Scholar
DecmanVFreemanMLKinchingtonPRHendricksRLImmune control of HSV-1 latencyViral Immunol200518346647316212525
PubMed Web of Science ®Google Scholar
LafonMLatent viral infections of the nervous system: role of the host immune responseRev Neurol (Paris)2009165121039104419906390
PubMed Web of Science ®Google Scholar
SheridanPABeckMAThe immune response to herpes simplex virus encephalitis in mice is modulated by dietary vitamin EJ Nutr2008138113013718156415
PubMed Web of Science ®Google Scholar
FeartCSamieriCBarberger-GateauPMediterranean diet and cognitive function in older adultsCurr Opin Clin Nutr Metab Care2010131141819834324
PubMed Web of Science ®Google Scholar
MartinCMOmega-3 fatty acids: proven benefit or just a ‘fish story?’Consult Pharm200823321021221421722118454584
PubMedGoogle Scholar
ChandraVPandavRDodgeHHIncidence of Alzheimer’s disease in a rural community in India: the Indo-US studyNeurology200157698598911571321
PubMed Web of Science ®Google Scholar
HogervorstESadjimimTYesufuAKreagerPRahardjoTBHigh tofu intake is associated with worse memory in elderly Indonesian men and womenDement Geriatr Cogn Disorder20082615057
PubMed Web of Science ®Google Scholar

Share icon
Back to Top

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.

People also read
Recommended articles
Cited by

To cite this article:

Reference style: APA Chicago Harvard

Citation copied to clipboard

Reference styles above use APA (6th edition), Chicago (16th edition) & Harvard (10th edition)

Download citation

Download a citation file in RIS format that can be imported by citation management software including EndNote, ProCite, RefWorks and Reference Manager.

Choose format: RIS BibTex RefWorks Direct Export

Choose options: Citation Citation & abstract Citation & references

Could lysine supplementation prevent Alzheimer’s dementia? A novel hypothesis

References

Information for

Open access

Opportunities

Help and information

Your download is now in progress and you may close this window

Login or register to access this feature

Could lysine supplementation prevent Alzheimer’s dementia? A novel hypothesis

References

Related research

To cite this article:

Download citation

Information for

Open access

Opportunities

Help and information

Keep up to date