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Review

A meta-analysis of levetiracetam for randomized placebo-controlled trials in patients with refractory epilepsy

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Pages 905-917 | Published online: 11 Apr 2019

References

  • ForsgrenLBeghiEOunASillanpääMThe epidemiology of epilepsy in Europe – a systematic reviewEur J Neurol200512424525310.1111/j.1468-1331.2004.00992.x15804240
  • ShorvonSDThe epidemiology and treatment of chronic and refractory epilepsyEpilepsia199637Suppl 2S1S310.1111/j.1528-1157.1996.tb06027.x
  • MacTLTranD-SQuetFOdermattPPreuxP-MTanCTEpidemiology, aetiology, and clinical management of epilepsy in Asia: a systematic reviewLancet Neurol20076653354310.1016/S1474-4422(07)70127-817509488
  • KwanPBrodieMJEarly identification of refractory epilepsyN Engl J Med2000342531431910.1056/NEJM20000203342050310660394
  • BettsTWaegemansTCrawfordPA multicentre, double-blind, randomized, parallel group study to evaluate the tolerability and efficacy of two oral doses of levetiracetam, 2,000 mg daily and 4,000 mg daily, without titration in patients with refractory epilepsySeizure200092808710.1053/seiz.2000.038010845730
  • LynchBALambengNNockaKThe synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetamProc Natl Acad Sci U S A2004101269861986610.1073/pnas.030820810115210974
  • De SmedtTRaedtRVonckKBoonPLevetiracetam: part II, the clinical profile of a novel anticonvulsant drugCNS Drug Rev2007131577810.1111/j.1527-3458.2007.00005.x17461890
  • OtoulCSmedtHDStockisALack of pharmacokinetic interaction of levetiracetam on carbamazepine, valproic acid, topiramate, and lamotrigine in children with epilepsyEpilepsia200748112111211510.1111/j.1528-1167.2007.01201.x17651416
  • PellockJMGlauserTABebinEMPharmacokinetic study of levetiracetam in childrenEpilepsia200142121574157910.1046/j.1528-1157.2001.41300.x11879369
  • Piña-GarzaJENordliDRJrRatingDYangHSchiemann-DelgadoJDuncanBAdjunctive levetiracetam in infants and young children with refractory partial-onset seizuresEpilepsia20095051141114910.1111/j.1528-1167.2008.01981.x19243423
  • EgunsolaOChoonaraISammonsHMThippeswamyTSafety of levetiracetam in paediatrics: a systematic reviewPLoS One2016113e014968610.1371/journal.pone.014968626930201
  • LiberatiAAltmanDGTetzlaffJThe PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaborationEpidemiol Biostat Public Health200964e1e34
  • DerSimonianRLairdNMeta-analysis in clinical trialsControl Clin Trials1986731771883802833
  • MantelNHaenszelWStatistical aspects of the analysis of data from retrospective studies of diseaseJ Natl Cancer Inst195922471974813655060
  • HigginsJPGreenSCochrane Handbook for Systematic Reviews of InterventionsChichester, UKJohn Wiley & Sons, Ltd2008
  • BeggCBMazumdarMOperating characteristics of a rank correlation test for publication biasBiometrics1994504108810.2307/25334467786990
  • EggerMSmithGDSchneiderMMinderCBias in meta-analysis detected by a simple, graphical testBMJ1997315710962963410.1136/bmj.315.7109.6299310563
  • PeltolaJCoetzeeCJiménezFOnce-daily extended-release levetiracetam as adjunctive treatment of partial-onset seizures in patients with epilepsy: a double-blind, randomized, placebo-controlled trialEpilepsia200950340641410.1111/j.1528-1167.2008.01817.x19317886
  • BoonPChauvelPPohlmann-EdenBOtoulCWroeSDose-response effect of levetiracetam 1,000 and 2,000 mg/day in partial epilepsyEpilepsy Res2002481–2778910.1016/S0920-1211(01)00323-011823112
  • CereghinoJJBitonVAboukhalilBDreifussFGauerLJLeppikILevetiracetam for partial seizures: results of a double-blind, randomized clinical trialNeurology200055223624210908898
  • TsaiJJYenDJHsihMSEfficacy and safety of levetiracetam (up to 2,000 mg/day) in Taiwanese patients with refractory partial seizures: a multicenter, randomized, double-blind, placebo-controlled studyEpilepsia2006471728116417534
  • XiaoZLiJ-MWangX-FEfficacy and safety of levetiracetam (3,000 mg/Day) as an adjunctive therapy in Chinese patients with refractory partial seizuresEur Neurol200961423323910.1159/00019710919176965
  • ZhouBZhangQTianLXiaoJStefanHZhouDEffects of levetiracetam as an add-on therapy on cognitive function and quality of life in patients with refractory partial seizuresEpilepsy Behav200812230531010.1016/j.yebeh.2007.10.00318024209
  • WuXHongZWuXMulticenter double-blind, randomized, placebo-controlled trial of levetiracetam as add-on therapy in Chinese patients with refractory partial-onset seizuresEpilepsia200950339810.1111/j.1528-1167.2008.01729.x18657175
  • Ben-MenachemEFalterUEfficacy and tolerability of levetiracetam 3,000 mg/d in patients with refractory partial seizures: a multicenter, double-blind, responder-selected study evaluating monotherapyEpilepsia200041101276128311051122
  • GlauserTAAyalaREltermanRDDouble-blind placebo-controlled trial of adjunctive levetiracetam in pediatric partial seizuresNeurology200666111654166016641323
  • InoueYYagiKIkedaAEfficacy and tolerability of levetiracetam as adjunctive therapy in Japanese patients with uncontrolled partial-onset seizuresPsychiatry Clin Neurosci2015691064064810.1111/pcn.1230025854635
  • LevisohnPMMintzMHunterSJYangHJonesJN01103 Levetiracetam Study GroupNeurocognitive effects of adjunctive levetiracetam in children with partial-onset seizures: a randomized, double-blind, placebo-controlled, noninferiority trialEpilepsia200950112377238910.1111/j.1528-1167.2009.02197.x19702752
  • NoachtarSAndermannEMeyvischPAndermannFGoughWBSchiemann-DelgadoJLevetiracetam for the treatment of idiopathic generalized epilepsy with myoclonic seizuresNeurology200870860710.1212/01.wnl.0000297512.18364.4018285535
  • BerkovicSFKnowltonRCLeroyRFSchiemannJFalterUPlacebo-controlled study of levetiracetam in idiopathic generalized epilepsyNeurology200769181751176017625106
  • ZhengXWuSXiaMLiQStudy on the therapeutic effect of levetiracetam as an additive therapy for refractory partial epilepsy and the relativity between levetiracetam and multidrug resistance gene: a randomised double-blind placebo-controlled trialChin J Contemp Neurol Neurosurg2009902173177
  • MbizvoGKDixonPHuttonJLMarsonAGLevetiracetam add-on for drug-resistant focal epilepsy: an updated Cochrane ReviewCochrane Database Syst Rev20129CD00190110.1002/14651858.CD001901.pub2
  • HalmaEde LouwAJAKlinkenbergSAldenkampAPIJffDMMajoieMBehavioral side-effects of levetiracetam in children with epilepsy: a systematic reviewSeizure201423968569110.1016/j.seizure.2014.06.00424981629
  • CramerJAPerrineKDevinskyOBryant-ComstockLMeadorKHermannBDevelopment and cross-cultural translations of a 31-item quality of life in epilepsy inventoryEpilepsia199839181889578017
  • FarmerCLeiter International Performance Scale-Revised (Leiter-R)New YorkSpringer New York2013
  • DumontRWillisJOVeizelKZibulskyJWide Range Assessment of Memory and Learning2nd edHobokenJohn Wiley & Sons, Inc2014
  • CostaJFareleiraFAscençãoRBorgesMSampaioCVaz-CarneiroAClinical comparability of the new antiepileptic drugs in refractory partial epilepsy: a systematic review and meta-analysisEpilepsia20115271280129110.1111/j.1528-1167.2011.03047.x21729036