Benefits of Combining Antiepileptic Drugs with Vitamin B12 on Redox Balance: Penicillin-Induced Experimental Epilepsy Model

References

• Milligan TA. Epilepsy: a clinical overview. Am J Med. 2021;134(7):840–847. doi:10.1016/j.amjmed.2021.01.038
   PubMed Web of Science ®Google Scholar
• Beghi E. The epidemiology of epilepsy. Neuroepidemiology. 2020;54(2):185–191. doi:10.1159/000503831
   PubMed Web of Science ®Google Scholar
• Łukawski K, Czuczwar SJ. Oxidative stress and neurodegeneration in animal models of seizures and epilepsy. Antioxidants. 2023;12(5):1–29. doi:10.3390/antiox12051049
   Web of Science ®Google Scholar
• Scheffer IE, Berkovic S, Capovilla G, et al. ILAE classification of the epilepsies: position paper of the ILAE commission for classification and terminology. Epilepsia. 2017;58(4):512–521. doi:10.1111/epi.13709
   PubMed Web of Science ®Google Scholar
• Vezzani A, Balosso S, Ravizza T. Neuroinflammatory pathways as treatment targets and biomarkers in epilepsy. Nat Rev Neurol. 2019;15(8):459–472. doi:10.1038/s41582-019-0217-x
   PubMed Web of Science ®Google Scholar
• Parsons ALM, Bucknor EMV, Castroflorio E, Soares TR, Oliver PL, Rial D. The interconnected mechanisms of oxidative stress and neuroinflammation in epilepsy. Antioxidants. 2022;11(1). doi:10.3390/antiox11010157
   Web of Science ®Google Scholar
• Cardenas-Rodriguez N, Huerta-Gertrudis B, Rivera-Espinosa L, et al. Role of oxidative stress in refractory epilepsy: evidence in patients and experimental models. Int J Mol Sci. 2013;14(1):1455–1476. doi:10.3390/ijms14011455
   PubMed Web of Science ®Google Scholar
• Taskin S, Celik H, Taskin A, Aksoy M, An I, Yesilova Y. Assessment of dynamic thiol-disulfide homeostasis in patients with lipoid proteinosis (Urbach-Wiethe syndrome). Rev Assoc Med Bras. 2022;68(9):1259–1263. doi:10.1590/1806-9282.20220333
   PubMed Web of Science ®Google Scholar
• Azzi A. Oxidative stress: what is it? Can it be measured? Where is it located? Can it be good or bad? Can it be prevented? Can it be cured? Antioxidants. 2022;11(8). doi:10.3390/antiox11081431
   Web of Science ®Google Scholar
• Erel O. A new automated colorimetric method for measuring total oxidant status. Clin Biochem. 2005;38(12):1103–1111. doi:10.1016/j.clinbiochem.2005.08.008
   PubMed Web of Science ®Google Scholar
• Erel O, Neselioglu S. A novel and automated assay for thiol/disulphide homeostasis. Clin Biochem. 2014;47(18):326–332. doi:10.1016/j.clinbiochem.2014.09.026
   PubMed Web of Science ®Google Scholar
• Fattorusso A, Matricardi S, Mencaroni E, et al. The pharmacoresistant epilepsy: an overview on existant and new emerging therapies. Front Neurol. 2021;12:1–15. doi:10.3389/fneur.2021.674483
   Web of Science ®Google Scholar
• Yang MT, Chou IC, Wang HS. Role of vitamins in epilepsy. Epilepsy Behav. 2023;139(21):109062. doi:10.1016/j.yebeh.2022.109062
   PubMedGoogle Scholar
• Tamaddonfard E, Farshid AA, Samadi F, Eghdami K. Effect of Vitamin B12 on functional recovery and histopathologic changes of tibial nerve-crushed rats. Drug Res. 2014;64(9):470–475. doi:10.1055/s-0033-1363219
   Google Scholar
• Reynolds E. Vitamin B12, folic acid, and the nervous system. Lancet Neurol. 2006;5(11):949–960. doi:10.1016/S1474-4422(06)70598-1
   PubMed Web of Science ®Google Scholar
• Ozsoy S. Effects of modafinil on epileptiform activity in absence epilepsy: results of a study in WAG/Rij rats. J Radiat Res Appl Sci. 2023;16(4):100684. doi:10.1016/j.jrras.2023.100684
   Web of Science ®Google Scholar
• Duran E, Taşkın A, Pehlivan B, Çelik H, Pehlivan VF, Taşkın S. Dynamic thiol disulphide homeostasis in the follow-up of the prognosis of patients treated for COVID-19 in the intensive care unit. Cureus. 2022;14(7). doi:10.7759/cureus.27542
   Google Scholar
• Erel O. A novel automated direct measurement method for total antioxidant capacity using a new generation, more stable ABTS radical cation. Clin Biochem. 2004;37(4):277–285. doi:10.1016/j.clinbiochem.2003.11.015
   PubMed Web of Science ®Google Scholar
• Pitkanen A, Lukasiuk K, Dudek FE, Staley KJ. Epileptogenesis. Cold Spring Harb Perspect Med. 2015;5:a022822. doi:10.1101/cshperspect.a022822
   PubMed Web of Science ®Google Scholar
• Borowicz-Reutt KK, Czuczwar SJ. Role of oxidative stress in epileptogenesis and potential implications for therapy. Pharmacol Rep. 2020;72(5):1218–1226. doi:10.1007/s43440-020-00143-w
   PubMed Web of Science ®Google Scholar
• Rho JM, Boison D. The metabolic basis of epilepsy. Nat Rev Neurol. 2022;18(6):333–347. doi:10.1038/s41582-022-00651-8
   PubMed Web of Science ®Google Scholar
• Circu ML, Aw TY. Reactive oxygen species, cellular redox systems, and apoptosis. Free Radic Biol Med. 2010;48(6):749–762. doi:10.1016/j.freeradbiomed.2009.12.022
   PubMed Web of Science ®Google Scholar
• Biswas S, Chida AS, Rahman I. Redox modifications of protein-thiols: emerging roles in cell signaling. Biochem Pharmacol. 2006;71(5):551–564. doi:10.1016/j.bcp.2005.10.044
   PubMed Web of Science ®Google Scholar
• Akünal Türel C, Yunusoğlu O. Oleanolic acid suppresses pentylenetetrazole-induced seizure in vivo. Int J Environ Health Res. 2023;33(5):529–540. doi:10.1080/09603123.2023.2167947
   PubMed Web of Science ®Google Scholar
• Menon B, Ramalingam K, Kumar RV. Low plasma antioxidant status in patients with epilepsy and the role of antiepileptic drugs on oxidative stress. Ann Indian Acad Neurol. 2014;17(4):398–404. doi:10.4103/0972-2327.144008
   PubMed Web of Science ®Google Scholar
• Güngör İ, Erdem AB, Kavaklı HŞ, Kösem A, Erel Ö, Neşelioğlu S. Evaluation of thiol-disulfide homeostasis and ischemia-modified albumin levels in patients presenting to the emergency department in the postictal period. Turk Noroloji Derg. 2023;29(2):118–125. doi:10.4274/tnd.2023.77012
   Google Scholar
• Kösem A, Yücel Ç, Titiz AP, et al. Evaluation of serum thiol-disulphide homeostasis parameters as oxidative stress markers in epilepsy patients. Acta Neurol Belg. 2021;121(6):1555–1559. doi:10.1007/s13760-020-01410-6
   PubMed Web of Science ®Google Scholar
• Gumuşsyayla S, Vural, G, Bektaş, H, Neşelioglu, S, Deniz, O, Erel, Ö. Evaluation of the dynamic thiol-disulphide homeostasis in patients with epilepsy. Arch Epilepsy. 2016;22(3):86–92. doi:10.14744/epilepsi.2016.86580
   Google Scholar
• Kocatürk M, Kirmit A. Evaluation of IL-10, IFN- γ, and thiol – disulfide homeostasis in patients with drug-resistant epilepsy. Neurol Sci. 2022;43:485–492.
   PubMed Web of Science ®Google Scholar
• Allahverdiyev O, Dzhafar S, Berköz M, Yıldırım M. Advances in current medication and new therapeutic approaches in epilepsy. East J Med. 2018;23(1):48–59. doi:10.5505/ejm.2018.62534
   Google Scholar
• Stahl SM. Anticonvulsants as mood stabilizers and adjuncts to antipsychotics: valproate, lamotrigine, carbamazepine, and oxcarbazepine and actions at voltage-gated sodium channels. J Clin Psychiatry. 2004;65(6):738–739. doi:10.4088/JCP.v65n0601
   PubMed Web of Science ®Google Scholar
• Filiz AK, Gumus E, Karabulut S, Tastemur Y, Taskiran AS. Protective effects of lamotrigine and vitamin B12 on pentylenetetrazole-induced epileptogenesis in rats. Epilepsy Behav. 2021;118:107915. doi:10.1016/j.yebeh.2021.107915
   PubMed Web of Science ®Google Scholar
• Fakhroo A, Al-Hammadi M, Fakhroo L, et al. The effect of high-dose methyl Vitamin B12 therapy on epileptogenesis in rats: an in vivo Study. Cureus. 2023;15(23):1–8. doi:10.7759/cureus.35929
   Google Scholar