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Case Report

Two grams of sarcosine in schizophrenia – is it too much? A potential role of glutamate-serotonin interaction

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Pages 263-266 | Published online: 04 Feb 2014

References

  • CarlssonAWatersNWatersSCarlssonMLNetwork interactions in schizophrenia – therapeutic implicationsBrain Res Brain Res Rev20003134234910719161
  • CoyleJTThe glutamatergic dysfunction hypothesis for schizophreniaHarv Rev Psychiatry199632412539384954
  • OlneyJWNewcomerJWFarberNBNMDA receptor hypofunction model of schizophreniaJ Psychiatr Res19993352353310628529
  • HuNWOndrejcakTRowanMJGlutamate receptors in preclinical research on Alzheimer’s disease: update on recent advancesPharmacol Biochem Behav201210085586221536064
  • MannKKieferFSpanagelRLittletonJAcamprosate: recent findings and future research directionsAlcohol Clin Exp Res2008321105111118540918
  • KantrowitzJJavittDCGlutamatergic transmission in schizophrenia: from basic research to clinical practiceCurr Opin Psychiatry2012259610222297716
  • de BartolomeisASarappaCMagaraSIasevoliFTargeting glutamate system for novel antipsychotic approaches: relevance for residual psychotic symptoms and treatment resistant schizophreniaEur J Pharmacol201268211122387855
  • López-MuñozFÁlamoCNeurobiological background for the development of new drugs in schizophreniaClin Neuropharmacol20113411112621586917
  • TuominenHJTiihonenJWahlbeckKGlutamatergic drugs for schizophreniaCochrane Database Syst Rev200619CD00373016625590
  • TsaiGLaneHYYangPChongMYLangeNGlycine transporter I inhibitor, N-methylglycine (sarcosine) added to antipsychotics for the treatment of schizophreniaBiol Psychiatry20045545245615023571
  • LaneHYChangYCLiuYCChiuCCTsaiGESarcosine or D-serine add-on treatment for acute exacerbation of schizophrenia: a randomized, double-blind, placebo-controlled studyArch Gen Psychiatry2005621196120416275807
  • LaneHYHuangCLWuPLLiuYCChangYCLinPYChenPWTsaiGGlycine transporter 1 inhibitor, N-methylglycine (sarcosine), added to clozapine for the treatment of schizophreniaBiol Psychiatry20066064564916780811
  • LaneHYLiuYCHuangCLChangYCLiauCHPerngCHTsaiGESarcosine (N-methylglycine) treatment for acute schizophrenia: a randomized, double-blind studyBiol Psychiatry20086391217659263
  • LaneHYLinCHHuangYJLiaoCHChangYCTsaiGEA randomized, double-blind, placebo-controlled comparison study of sarcosine (N-methylglycine) and D-serine add-on treatment for schizophreniaInt J Neuropsychopharmacol20101345146019887019
  • HashimotoKMalchowBFalkaiPSchmittAGlutamate modulators as potential therapeutic drugs in schizophrenia and affective disordersEur Arch Psychiatry Clin Neurosci201326336737723455590
  • SinghSPSinghVMeta-analysis of the efficacy of adjunctive NMDA receptor modulators in chronic schizophreniaCNS Drugs20112585988521936588
  • TsaiGELinPYStrategies to enhance N-methyl-D-aspartate receptor-mediated neurotransmission in schizophrenia, a critical review and meta-analysisCurr Pharm Des20101652253719909229
  • Heresco-LevyUErmilovMShimoniJShapiraBSilipoGJavittDCPlacebo-controlled trial of D-cycloserine added to conventional neuroleptics, olanzapine, or risperidone in schizophreniaAm J Psychiatry200215948048211870017
  • Heresco-LevyUJavittDCErmilovMSilipoGShimoniJDouble-blind, placebo-controlled, crossover trial of D-cycloserine adjuvant therapy for treatment-resistant schizophreniaInt J Neuropsychopharmacol1998113113511281957
  • Heresco-LevyUJavittDCErmilovMMordelCHorowitzAKellyDDouble-blind, placebo-controlled, crossover trial of glycine adjuvant therapy for treatment-resistant schizophreniaBr J Psychiatry19961696106178932891
  • StrzeleckiDKropiwnickiPRabe-JabłońskaJ[Augmentation of antipsychotics with glycine may ameliorate depressive and extrapyramidal symptoms in schizophrenic patients: a preliminary 10-week open-label study]Psychiatr Pol201347609620 Polish
  • HuangCCWeiIHHuangCLInhibition of glycine transporter-I as a novel mechanism for the treatment of depressionBiol Psychiatry20137473474123562005
  • DiazgranadosNIbrahimLBrutscheNEA randomized add-on trial of an N-methyl-D-aspartate antagonist in treatment-resistant bipolar depressionArch Gen Psychiatry20106779380220679587
  • FergusonJMShingletonRNAn open-label, flexible-dose study of memantine in major depressive disorderClin Neuropharmacol20073013614417545748
  • MuhonenLHLönnqvistJJuvaKAlhoHDouble-blind, randomized comparison of memantine and escitalopram for the treatment of major depressive disorder comorbid with alcohol dependenceJ Clin Psychiatry20086939239918348597
  • PilcAChakiSNowakGWitkinJMMood disorders: regulation by metabotropic glutamate receptorsBiochem Pharmacol200875997100618164691
  • AraiACKesslerMPharmacology of ampakine modulators: from AMPA receptors to synapses and behaviorCurr Drug Targets2007858360217504103
  • SinghSPSinghVKarNChanKEfficacy of antidepressants in treating the negative symptoms of chronic schizophrenia: meta-analysisBr J Psychiatry201019717417920807960
  • JavittDCGlycine transport inhibitors in the treatment of schizophreniaHandb Exp Pharmacol201221336739923027421
  • AlberatiDMoreauJLLengyelJGlycine reuptake inhibitor RG1678: a pharmacologic characterization of an investigational agent for the treatment of schizophreniaNeuropharmacology2012621152116122138164
  • HopkinsCRACS Chemical neuroscience molecule spotlight on RG1678ACS Chem Neurosci2011268568622860161
  • de BartolomeisABuonaguroEFIasevoliFSerotonin-glutamate and serotonin-dopamine reciprocal interactions as putative molecular targets for novel antipsychotic treatments: from receptor heterodimers to postsynaptic scaffolding and effector proteinsPsychopharmacology (Berl)201322511923179966
  • Medical Universtity of LodzEffect of Sarcosine on Symptomatology, Quality of Life, Oxidative Stress and Glutamatergic Parameters in Schizophrenia (PULSAR) Available from: http://clinicaltrials.gov/show/NCT01503359. NLM identifier: NCT01503359Accessed December 12, 2013