References
- National Institute of Mental HealthNumbers count: mental disorders in AmericaBethesda, MDNational Institute of Mental Health2013 Available from: http://www.nimh.nih.gov/health/publications/the-numbers-count-mental-disorders-in-america/index.shtml#SchizophreniaAccessed March 6, 2015
- US Census BureauAge and sex composition: 2010 (C2010BR-03)Washington, DCUS Census Bureau2011 Available from: http://www.census.gov/prod/cen2010/briefs/c2010br-03.pdfAccessed March 6, 2015
- SchoepfDUppalHPotluriRHeunRPhysical comorbidity and its relevance on mortality in schizophrenia: a naturalistic 12-year follow-up in general hospital admissionsEur Arch Psychiatry Clin Neurosci201426432823942824
- EmsleyRChilizaBAsmalLHarveyBHThe nature of relapse in schizophreniaBMC Psychiatry2013135023394123
- MuenchJHamerAMAdverse effects of antipsychotic medicationsAm Fam Physician20108161762220187598
- BruijnzeelDSuryadevaraUTandonRAntipsychotic treatment of schizophrenia: an updateAsian J Psychiatr2014113725216917
- ChaDSMcIntyreRSTreatment-emergent adverse events associated with atypical antipsychoticsExpert Opin Pharmacother2012131587159822304541
- BasuAMeltzerHYTying comparative effectiveness information to decision-making and the future of comparative effectiveness research designs: the case for antipsychotic drugsJ Comp Eff Res20121217118024237376
- HermesEDSernyakMRosenheckRImpact of a program encouraging the use of generic antipsychoticsAm J Manag Care2012188307314
- SmithKJBaikSHReynoldsCFRollmanBLZhangYCost-effectiveness of Medicare drug plans in schizophrenia and bipolar disorderAm J Manag Care20131925563
- MarderSREssockSMMillerALPhysical health monitoring of patients with schizophreniaAm J Psychiatry20041611334134915285957
- LehmanAFLiebermanJADixonLBPractice guideline for the treatment of patients with schizophrenia, second editionAm J Psychiatry200416115615000267
- American Diabetes Association, American Psychiatric Association, American Association of Clinical Endocrinologists, North American Association for the Study of ObesityConsensus development conference on antipsychotic drugs and obesity and diabetesDiabetes Care20042759660114747245
- MeyerJMAntipsychotics and metabolics in the post-CATIE eraCurr Top Behav Neurosci20104234221312396
- LeuchtSCiprianiLSpineliLComparative efficacy and toler-ability of 15 antipsychotic drugs in schizophrenia: a multiple-treatments meta-analysisLancet201338295196223810019
- CitromeLJohnstonSNadkarniASheehanJJKamatSAKalsekarIPrevalence of pre-existing risk factors for adverse events associated with atypical antipsychotics among commercially insured and Medicaid insured patients newly initiating atypical antipsychoticsCurr Drug Saf2014922723524909573
- KennedyWKJannMWKutscherECClinically significant drug interactions with atypical antipsychoticsCNS Drugs2013271021104824170642
- KellerWRFischerBAMcMahonRCommunity adherence to schizophrenia treatment and safety monitoring guidelinesJ Nerv Ment Dis201420261224375205
- FalkaiPWobrockTLiebermanJWorld Federation of Societies of Biological Psychiatry (WFSBP) guidelines for biological treatment of schizophrenia, Part 1: acute treatment of schizophreniaWorld J Biol Psychiatry20056313219116173147
- GardnerKNBostwickJRAntipsychotic treatment response in schizophreniaAm J Health Syst Pharm2012691872187923111671
- TargumSDPestreichLReksoprodjoPPereiraHGuindonCHochfeldMA global measure to assess switching antipsychotic medications in the treatment of schizophreniaHum Psychopharmacol20122745546322826027
- Novartis Pharmaceuticals Corp. Clozaril (clozapine) Available from: https://www.pharma.us.novartis.com/product/pi/pdf/Clozaril.pdfAccessed May 11, 2015
- CitromeLNasrallahHAOn-label on the table: what the package insert informs us about the tolerability profile of oral atypical antipsychotics, and what it does notExpert Opin Pharmacother201213111599161322017361
- AstraZeneca Pharmaceuticals LPSeroquel (quetiapine) Available from: http://www1.astrazeneca-us.com/pi/Seroquel.pdfAccessed March 6, 2015
- Eli Lilly and CompanyZyprexa (olanzapine) Available from: http://pi.lilly.com/us/zyprexa-pi.pdfAccessed March 6, 2015
- Forest Pharmaceutical IncSaphris (asenapine) Available from: http://pi.actavis.com/data_stream.asp?product_group=1908&p=pi&language=EAccessed March 6, 2015
- Janssen Pharmaceuticals IncInvega (paliperidone) Available from: http://www.janssencns.com/sites/default/files/pdf/invega/invega.pdfAccessed March 17, 2015
- Janssen Pharmaceuticals IncRisperdal (risperidone) Available from: http://www.janssenpharmaceuticalsinc.com/assets/risperdal.pdfAccessed March 6, 2015
- Novartis Pharmaceuticals CorpFanapt (iloperidone) Available from: http://www.fanapt.com/product/pi/pdf/fanapt.pdfAccessed March 10, 2015
- Otsuka Pharmaceutical Co., Ltd.Abilify (aripiprazole) Available from: http://www.otsuka-us.com/Documents/Abilify.PI.pdfAccessed March 6, 2015
- Pfizer, IncGeodon (ziprasidone) Available from: http://labeling.pfizer.com/ShowLabeling.aspx?id=584Accessed March 6, 2015
- Sunovion Pharmaceuticals IncLatuda (lurasidone hydrochloride) Available from: http://www.latuda.com/LatudaPrescribingInformation.pdfAccessed March 10, 2015
- MitchellAJVancampfortDDe HerdtAYuWDe HertMIs the prevalence of metabolic syndrome and metabolic abnormalities increased in early schizophrenia? A comparative meta-analysis of first-episode, untreated and treated patientsSchizophr Bull20133929530522927670
- ViertioSTuulio-HenrikssonAPeralaJActivities of daily living, social functioning and their determinants in persons with psychotic disorderEur Psychiatry20122740941521377336
- PapageorgiouGCanasFZinkMRossiACountry differences in patient characteristics and treatment in schizophrenia: data from a physician-based survey in EuropeEur Psychiatry201126172821440220
- MillierAAmriIBoyerLAuquierPToumiMUtility decrements associated with side effects in schizophreniaJ Med Econ20141785386125211094
- OzekiYFujiiKKurimotoQTc prolongation and antipsychotic medications in a sample of 1017 patients with schizophreniaProg Neuropsychopharmacol Biol Psychiatry20103440140520079791
- YangFDWangXQLiuXPSex difference in QTc prolongation in chronic institutionalized patients with schizophrenia on long-term treatment with typical and atypical antipsychoticsPsychopharmacology (Berl)201121691621301815
- Riechler-RosslerARybakowskiJKPfluegerMOHyperpro-lactemia in antipsychotic-naïve patients with first-episode psychosisPsychol Med2013432571258223590895
- BusheCShawMPrevalence of hyperprolactinaemia in a naturalistic cohort of schizophrenia and bipolar outpatients during treatment with typical and atypical antipsychoticsJ Psychopharmacol20072176877317606473
- KinonBJLiu-SeifertHStaufferVLJacobJBone loss associated with hyperprolactinemia in patients with schizophreniaClin Schiz Related Psychoses201373115123
- StubbsBDe HertMSepehryAAA meta-analysis of prevalence estimates and moderators of low bone mass in people with schizophreniaActa Psychiatr Scand2014130647048625041606
- KarthikMSKulharaPChakrabartiSAttitude towards second-generation antipsychotics among patients with schizophrenia and their relativesHum Psychopharmacol20132845746523784674
- BaggaleyMSexual dysfunction in schizophrenia: focus on recent evidenceHum Psychopharmacol20082320120918338766
- Abdel-BakiALetourneauGMorinCNgAResumption of work or studies after first episode psychosis: the impact of vocational case managementEarly Interv Psychiatry2013739139823347401
- MeltzerHYOutcome in schizophrenia: beyond symptom reductionJ Clin Psychiatry199960310073370
- VargasGStrassnigMSabbagSThe course of vocational functioning in patients with schizophrenia: re-examining social driftSchizophr Res Cogn201414146
- HaroJMNovickDPerrinEBertschJKnappMSymptomatic remission and patient quality of life in an observational study of schizophrenia: is there a relationship?Psychiatry Res201422016316925194449
- WatersFNaikNRockDSleep, fatigue, and functional health in psychotic patientsSchizophr Res Treatment2013201342582623738067
- PeraltaVde JalonEGCamposMSCuestaMJPhenomenological differences between spontaneous and drug-related extrapyramidal syndromes in patients with schizophrenia-spectrum disordersJ Clin Psychopharm201333438440
- KaneJMFleischhackerWWHansenLPerlisRPikalovA3rdAssunção-TalbottSAkathisia: an updated review focusing on second-generation antipsychoticsJ Clin Psychiatry20097062764319389331
- CitromeLA review of the pharmacology, efficacy and tolerability of recently approved and upcoming oral antipsychotics: an evidence-based medicine approachCNS Drugs2013271187991124062193
- VolavkaJCitromeLOral antipsychotics for the treatment of schizophrenia: heterogeneity in efficacy and tolerability should drive decision-makingExpert Opin Pharmacother200910121917192819558339
- CitromeLKalsekarIBakerRAHebdenTA review of real-world data on the effects of aripiprazole on weight and metabolic outcomes in adultsCurr Med Res Opin2014301629164124666104
- LasicDBevandaMBosnjakNUglešićBGlavinaTFranićTMetabolic syndrome and inflammation markers in patients with schizophrenia and recurrent depressive disorderPsychiatr Danub20142621421925191767
- KucerovaJBabinskaZHorskaKKotolovaHThe common pathophysiology underlying the metabolic syndrome, schizophrenia, and depression: a reviewBiomed Pap Med Fac Univ Palacky Olomourc Czech Repub20151592208214
- RojoLEGasparPASilvaHMetabolic syndrome and obesity among users of second generation antipsychotics: a global challenge for modern psychopharmacologyPharmacol Res Epub2015725
- LeungJYBarrAMProcyshynRMHonerWGPangCCCardiovascular side-effects of antipsychotic drugs: the role of the autonomic nervous systemPharmacol Ther2012135211312222565090
- HasnainMViewegWVQTc interval prolongation and torsade de pointes associated with second-generation antipsychotics and antidepressants: a comprehensive reviewCNS Drugs2014281088792025168784
- De HertMDetrauxJPeuskensJSecond-generation and newly approved antipsychotics, serum prolactin levels and sexual dysfunctions: a critical literature reviewExpert Opin Drug Saf201413560562424697217
- PeuskensJPaniLDetrauxJDe HertMThe effects of novel and newly approved antipsychotics on serum prolactin levels: a comprehensive reviewCNS Drugs201428542145324677189
- BargiotaSIBonotisKSMessinisIEAngelopoulosNVThe effects of antipsychotics on prolactin levels and women’s menstruationSchizophr Res Treatment2013201350269724490071
- JustMJThe influence of atypical antipsychotic drugs on sexual functionNeuropsychiatr Dis Treat2015111655166126185449
- GaoKGanocySJGajwaniPMuzinaDJKempDECalabreseJRA review of sensitivity and tolerability of antipsychotics in patients with bipolar disorder or schizophrenia: focus on somnolenceJ Clin Psychiatry200869230230918211129
- BrattiIMKaneJMMarderSRChronic restlessness with antipsychot-icsAm J Psychiatry2007164111648165417974927
- PelusoMJLewisSWBarnesTRJonesPBExtrapyramidal motor side-effects of first- and second-generation antipsychotic drugsBr J Psychiatry2012200538739222442101
- ShayeganDKStahlSMAtypical antipsychotics: matching receptor profile to individual patient’s clinical profileCNS Spectr2004910 Suppl 1161415475871
- DarganiNVMalhotraAKSafety profile of iloperidone in the treatment of schizophreniaExpert Opin Drug Saf201413224124624206391
- StahlSMRole of α1 adrenergic antagonism in the mechanism of action of iloperidone: reducing extrapyramidal symptomsCNS Spectr201318628528824300463
- Matsui-SakataAOhtaniHSawadaYReceptor occupancy-based analysis of the contributions of various receptors to antipsychotics-induced weight gain and diabetes mellitusDrug Metab Pharmacokinet200520536837816272755
- StahlSMStahl’s Essential Psychopharmacology: Neuroscientific Basis and Practical Applications4th edCambridgeCambridge University Press2013