Optimal dose of etanercept in the treatment of rheumatoid arthritis

References

• PincusTCallahanLFSaleWGBrooksALPayneLEVaughnWKSevere functional declines, work disability, and increased mortality in seventy-five rheumatoid arthritis patients studied over nine yearsArthritis Rheum19842788648726431998
   PubMed Web of Science ®Google Scholar
• Aviña-ZubietaJAChoiHKSadatsafaviMEtminanMEsdaileJMLacailleDRisk of cardiovascular mortality in patients with rheumatoid arthritis: a meta-analysis of observational studiesArthritis Rheum200859121690169719035419
   PubMed Web of Science ®Google Scholar
• SmolenJSAletahaDBijlsmaJWT2T Expert CommitteeTreating rheumatoid arthritis to target: recommendations of an international task forceAnn Rheum Dis201069463163720215140
   PubMed Web of Science ®Google Scholar
• BrennanFMChantryDJacksonAMainiRFeldmannMInhibitory effect of TNF alpha antibodies on synovial cell interleukin-1 production in rheumatoid arthritisLancet1989286572442472569055
   PubMed Web of Science ®Google Scholar
• MorelandLWBaumgartnerSWSchiffMHTreatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion proteinN Engl J Med199733731411479219699
   PubMed Web of Science ®Google Scholar
• MohlerKMTorranceDSSmithCASoluble tumor necrosis factor (TNF) receptors are effective therapeutic agents in lethal endotoxemia and function simultaneously as both TNF carriers and TNF antagonistsJ Immunol19931513154815618393046
   PubMed Web of Science ®Google Scholar
• MorelandLWSchiffMHBaumgartnerSWEtanercept therapy in rheumatoid arthritis. A randomized, controlled trialAnn Intern Med1999130647848610075615
   PubMed Web of Science ®Google Scholar
• FelsonDTAndersonJJBoersMAmerican College of Rheumatology. Preliminary definition of improvement in rheumatoid arthritisArthritis Rheum1995387277357779114
   PubMed Web of Science ®Google Scholar
• BathonJMMartinRWFleischmannRMA comparison of etanercept and methotrexate in patients with early rheumatoid arthritisN Engl J Med2000343221586159311096165
   PubMed Web of Science ®Google Scholar
• KeystoneECSchiffMHKremerJMOnce-weekly administration of 50 mg etanercept in patients with active rheumatoid arthritis: results of a multicenter, randomized, double-blind, placebo-controlled trialArthritis Rheum200450235336314872476
   PubMed Web of Science ®Google Scholar
• WeinblattMESchiffMHRudermanEMEfficacy and safety of etanercept 50 mg twice a week in patients with rheumatoid arthritis who had a suboptimal response to etanercept 50 mg once a week: results of a multicenter, randomized, double-blind, active drug-controlled studyArthritis Rheum20085871921193018576334
   PubMed Web of Science ®Google Scholar
• JohnsenAKSchiffMHMeasePJComparison of 2 doses of etanercept (50 vs 100 mg) in active rheumatoid arthritis: a randomized double blind studyJ Rheumatol200633465966416482646
   PubMed Web of Science ®Google Scholar
• RichEMorelandLWAlarcónGSPaucity of radiographic progression in rheumatoid arthritis treated with methotrexate as the first disease modifying antirheumatic drugJ Rheumatol19992622592619972955
   PubMed Web of Science ®Google Scholar
• GenoveseMCBathonJMMartinRWEtanercept versus methotrexate in patients with early rheumatoid arthritis: two-year radiographic and clinical outcomesArthritis Rheum20024661443145012115173
   PubMed Web of Science ®Google Scholar
• KlareskogLvan der HeijdeDde JagerJPTEMPO (Trial of Etanercept and Methotrexate with Radiographic Patient Outcomes) study investigatorsTherapeutic effect of the combination of etanercept and methotrexate compared with each treatment alone in patients with rheumatoid arthritis: double-blind randomised controlled trialLancet2004363941067568115001324
   PubMed Web of Science ®Google Scholar
• van der HeijdeDKlareskogLRodriguez-ValverdeVTEMPO Study InvestigatorsComparison of etanercept and methotrexate, alone and combined, in the treatment of rheumatoid arthritis: two-year clinical and radiographic results from the TEMPO study, a double-blind, randomized trialArthritis Rheum20065441063107416572441
   PubMed Web of Science ®Google Scholar
• van der HeijdeDKlareskogLLandewéRDisease remission and sustained halting of radiographic progression with combination etanercept and methotrexate in patients with rheumatoid arthritisArthritis Rheum200756123928393918050208
   PubMed Web of Science ®Google Scholar
• HuDBaoCChenSA comparison study of a recombinant tumor necrosis factor receptor:Fc fusion protein (rhTNFR:Fc) and methotrexate in treatment of patients with active rheumatoid arthritis in ChinaRheumatol Int200929329730318704426
   PubMed Web of Science ®Google Scholar
• WeinblattMEKremerJMBankhurstADA trial of etanercept, a recombinant tumor necrosis factor receptor: Fc fusion protein, in patients with rheumatoid arthritis receiving methotrexateN Engl J Med199934042532599920948
   PubMed Web of Science ®Google Scholar
• EmeryPBreedveldFCHallSComparison of methotrexate monotherapy with a combination of methotrexate and etanercept in active, early, moderate to severe rheumatoid arthritis (COMET): a randomised, double-blind, parallel treatment trialLancet2008372963637538218635256
   PubMed Web of Science ®Google Scholar
• EmeryPKvienTKCombeBCombination etanercept and methotrexate provides better disease control in very early (≤4 months) versus early rheumatoid arthritis (>4 months and <2 years): post hoc analyses from the COMET studyAnn Rheum Dis201271698999222402142
   PubMed Web of Science ®Google Scholar
• MorelandLWO’DellJRPaulusHETEAR InvestigatorsA randomized comparative effectiveness study of oral triple therapy versus etanercept plus methotrexate in early aggressive rheumatoid arthritis: the treatment of Early Aggressive Rheumatoid Arthritis TrialArthritis Rheum20126492824283522508468
   PubMed Web of Science ®Google Scholar
• KamedaHUekiYSaitoKJapan Biological Agent Study Integrated ConsortiumEtanercept (ETN) with methotrexate (MTX) is better than ETN monotherapy in patients with active rheumatoid arthritis despite MTX therapy: a randomized trialMod Rheumatol201020653153820574649
   PubMed Web of Science ®Google Scholar
• KamedaHKanbeKSatoEContinuation of methotrexate resulted in better clinical and radiographic outcomes than discontinuation upon starting etanercept in patients with rheumatoid arthritis: 52-week results from the JESMR studyJ Rheumatol20113881585159221572151
   PubMed Web of Science ®Google Scholar
• van RielPLTaggartAJSanyJAdd Enbrel or Replace Methotrexate Study InvestigatorsEfficacy and safety of combination etanercept and methotrexate versus etanercept alone in patients with rheumatoid arthritis with an inadequate response to methotrexate: the ADORE studyAnn Rheum Dis200665111478148316464988
   PubMed Web of Science ®Google Scholar
• O’DellJRMikulsTRTaylorTHCSP 551 RACAT InvestigatorsTherapies for active rheumatoid arthritis after methotrexate failureN Engl J Med252013369430731823755969
   PubMed Web of Science ®Google Scholar
• O’DellJRPetersenKLeffREtanercept in combination with sulfasalazine, hydroxychloroquine, or gold in the treatment of rheumatoid arthritisJ Rheumatol200633221321816358366
   PubMed Web of Science ®Google Scholar
• CombeBCodreanuCFioccoUEtanercept European Investigators Network (Etanercept Study 309 Investigators)Etanercept and sulfasalazine, alone and combined, in patients with active rheumatoid arthritis despite receiving sulfasalazine: a double-blind comparisonAnn Rheum Dis200665101357136216606651
   PubMed Web of Science ®Google Scholar
• CombeBCodreanuCFioccoUEtanercept European Investigators NetworkEfficacy, safety and patient-reported outcomes of combination etanercept and sulfasalazine versus etanercept alone in patients with rheumatoid arthritis: a double-blind randomised 2-year studyAnn Rheum Dis20096871146115218794178
   PubMed Web of Science ®Google Scholar
• StrangfeldAHierseFKekowJComparative effectiveness of tumour necrosis factor alpha inhibitors in combination with either methotrexate or leflunomideAnnals of the rheumatic diseases200968121856186219126559
   PubMed Web of Science ®Google Scholar
• De StefanoRFratiENargiFComparison of combination therapies in the treatment of rheumatoid arthritis: leflunomide-anti-TNF-alpha versus methotrexate-anti-TNF-alphaClinical Rheumatology201029551752420082236
   PubMed Web of Science ®Google Scholar
• SaleemBKeenHGoebVPatients with RA in remission on TNF blockers: when and in whom can TNF blocker therapy be stopped?Ann Rheum Dis20106991636164220421345
   PubMed Web of Science ®Google Scholar
• SmolenJSNashPDurezPMaintenance, reduction, or withdrawal of etanercept after treatment with etanercept and methotrexate in patients with moderate rheumatoid arthritis (PRESERVE): a randomised controlled trialLancet2013381987091892923332236
   PubMed Web of Science ®Google Scholar
• van VollenhovenRVFranck-LatssonKIn rheumatoid arthritis patients with stable low disease activity on methotrexate plus etanercept, continuation of etanercept at 50mg or 25mg weekly are both clinically superior to discontinuation: results from a randomized, 3-arm, double-blind studyAnn Rheumatic Dis2013723434
   Google Scholar
• EmeryPSzumskiARadiographic progression in patients with early arthritis treated with etanercept. results from the PRIZE studyAnn Rheumatic Dis201372Suppl 3399
   Google Scholar
• EmeryPSzumskiAEarly initiated etanercept plus methotrexate treatment induces remission in patients with either moderate or severe rheumatoid arthritisAnn Rheumatic Dis201372Suppl 3603
   Google Scholar
• EmeryPHammoudehMAssessing maintenance of remission with reduced dose etanercept plus methotrexate, methotrexate alone, or placebo in patients with early rheumatoid arthritis who achieved remission with etanercept and methotrexate: the PRIZE studyAnn Rheumatic Dis201372Suppl 3399
   Google Scholar
• van DongenHvan AkenJLardLREfficacy of methotrexate treatment in patients with probable rheumatoid arthritis: a double-blind, randomized, placebo-controlled trialArthritis Rheum20075651424143217469099
   PubMed Web of Science ®Google Scholar
• SaleemBMackieSQuinnMDoes the use of tumour necrosis factor antagonist therapy in poor prognosis, undifferentiated arthritis prevent progression to rheumatoid arthritis?Ann Rheum Dis20086781178118018234715
   PubMed Web of Science ®Google Scholar
• VilleneuveNamEHensorJLPreliminary results of a multicentre randomised controlled trial of etanercept and methotrexate to induce remission in patients with newly diagnosed inflammatory arthritisArthritis Rheumatism20116310246521520010
   PubMed Web of Science ®Google Scholar
• RouxCHBreuilVValerioLEtanercept compared to intraarticular corticosteroid injection in rheumatoid arthritis: double-blind, randomized pilot studyJ Rheumatol20113861009101121406499
   PubMed Web of Science ®Google Scholar
• BliddalHTerslevLQvistgaardEA randomized, controlled study of a single intra-articular injection of etanercept or glucocorticosteroids in patients with rheumatoid arthritisScand J Rheumatol200635534134517062431
   PubMed Web of Science ®Google Scholar
• van der BijlAETengYKvan OosterhoutMBreedveldFCAllaartCFHuizingaTWEfficacy of intraarticular infliximab in patients with chronic or recurrent gonarthritis: a clinical randomized trialArthritis Rheum200961797497819565559
   PubMed Web of Science ®Google Scholar
• LethabyALopez-OlivoMAMaxwellLBurlsATugwellPWellsGAEtanercept for the treatment of rheumatoid arthritisCochrane Database Rev20135CD004525
   PubMed Web of Science ®Google Scholar
• LeonardiCLPowersJLMathesonRTEtanercept Psoriasis Study GroupEtanercept as monotherapy in patients with psoriasisN Engl J Med2003349212014202214627786
   PubMed Web of Science ®Google Scholar
• GordonKBGottliebABLeonardiCLClinical response in psoriasis patients discontinued from and then reinitiated on etanercept therapyJ Dermatolog Treat200617191716467018
   PubMed Web of Science ®Google Scholar
• PappKATyringSLahfaMEtanercept Psoriasis Study GroupA global phase III randomized controlled trial of etanercept in psoriasis: safety, efficacy, and effect of dose reductionBr J Dermatol200515261304131215948997
   PubMed Web of Science ®Google Scholar
• JamnitskiAKrieckaertCLNurmohamedMTPatients non-responding to etanercept obtain lower etanercept concentrations compared with responding patientsAnn Rheum Dis2012711889121914626
   PubMed Web of Science ®Google Scholar
• NamJLVilleneuveEHensorEMRemission induction comparing infliximab and high-dose intravenous steroid, followed by treat-to-target: a double-blind, randomised, controlled trial in new-onset, treatment-naive, rheumatoid arthritis (the IDEA study)Ann Rheum Dis2014731758523912798
   PubMed Web of Science ®Google Scholar
• O’DellJRCurtisJRMikulsTRTEAR Trial InvestigatorsValidation of the methotrexate-first strategy in patients with early, poor-prognosis rheumatoid arthritis: results from a two-year randomized, double-blind trialArthritis Rheum20136581985199423686414
   PubMed Web of Science ®Google Scholar
• TanakaYTakeuchiTMimoriTRRR study investigatorsDiscontinuation of infliximab after attaining low disease activity in patients with rheumatoid arthritis: RRR (remission induction by Remicade in RA) studyAnn Rheum Dis20106971286129120360136
   PubMed Web of Science ®Google Scholar
• MatsubaraTOhtaSMukaiMoRion STUdy GRoUp: Abatacept biologic-free remission study in established rheumatoid arthritis patientsAnn Rheumatic Dis201372Suppl 3613
   Google Scholar
• KavanaughAEmeryPFleischmannRvan VollenhovenRFPavelkaKDurezPWithdrawal of adalimumab in early rheumatoid arthritis patients who attained stable low disease activity with adalimumab plus methotrexate: results of a phase 4, double-blind, placebo-controlled trial. [abstract]Arthritis Rheumatism201163Suppl 101699
   Google Scholar
• National Institute for Health and Care ExcellenceAdalimumab, Etanercept, and Infliximab for the Treatment of Rheumatoid Arthritis2007 Available at: http://publications.nice.org.uk/-etanercept-and-Infliximab-for-the-treatment-of-rheumatoid-arthritis-ta130Accessed December 18, 2013
   Google Scholar