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Clinical Ophthalmology Volume 14, 2020 - Issue
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Original Research

Comparison of the Intraocular Pressure-Lowering Efficacy and Safety of the Brinzolamide/Brimonidine Fixed-Dose Combination versus Concomitant Use of Brinzolamide and Brimonidine for Management of Open-Angle Glaucoma or Ocular Hypertension

Ningli Wang1 Beijing Tongren Eye Center, Beijing, People’s Republic of ChinaCorrespondence[email protected]
,
Da-Wen Lu2 Tri-Service General Hospital, Taipei, Taiwan
,
Yingzi Pan3 Peking University First Hospital, Beijing, People’s Republic of China
,
Yury Astakhov4 Pavlov First Saint Petersburg State Medical University, Saint Petersburg, Russia
,
Tatyana Iureva5 Irkutsk Branch of the Academician S.N. Fyodorov Eye Microsurgery Federal State Institution, Irkutsk, Russia
,
Adeniyi Adewale6 Novartis Pharmaceuticals Corporation, Fort Worth, TX, USA
&
Thomas M Walker6 Novartis Pharmaceuticals Corporation, Fort Worth, TX, USA
 show all
Pages 221-230 | Published online: 23 Jan 2020

References

  • Weinreb RN, Khaw PT. Primary open-angle glaucoma. Lancet. 2004;363(9422):1711–1720. doi:10.1016/S0140-6736(04)16257-0
  • Gordon MO, Kass MA. What we have learned from the ocular hypertension treatment study. Am J Ophthalmol. 2018;189:xxiv–xxvii. doi:10.1016/j.ajo.2018.02.016
  • Leibowitz HM, Krueger DE, Maunder LR, et al. The framingham eye study monograph: an ophthalmological and epidemiological study of cataract, glaucoma, diabetic retinopathy, macular degeneration, and visual acuity in a general population of 2631 adults, 1973–1975. Surv Ophthalmol. 1980;24(Suppl):335–610.
  • Heijl A, Leske MC, Bengtsson B, et al. Reduction of intraocular pressure and glaucoma progression: results from the early manifest glaucoma trial. Arch Ophthalmol. 2002;120(10):1268–1279. doi:10.1001/archopht.120.10.1268
  • Blumberg D, Skaat A, Liebmann JM. Emerging risk factors for glaucoma onset and progression. Prog Brain Res. 2015;221:81–101.
  • Garway-Heath DF, Crabb DP, Bunce C, et al. Latanoprost for open-angle glaucoma (UKGTS): a randomised, multicentre, placebo-controlled trial. Lancet. 2015;385(9975):1295–1304. doi:10.1016/S0140-6736(14)62111-5
  • Asian Pacific Glaucoma Society. Asia Pacific glaucoma guidelines. 3 Edition. 2016. Available from: https://www.apglaucomasociety.org/Public/Public/Resources/APGG.aspx. Accessed October 28, 2018.
  • Noecker RJ. The management of glaucoma and intraocular hypertension: current approaches and recent advances. Ther Clin Risk Manag. 2006;2(2):193–206. doi:10.2147/tcrm.2006.2.issue-2
  • Fechtner RD, Realini T. Fixed combinations of topical glaucoma medications. Curr Opin Ophthalmol. 2004;15(2):132–135. doi:10.1097/00055735-200404000-00013
  • Sleath B, Robin AL, Covert D, Byrd JE, Tudor G, Svarstad B. Patient-reported behavior and problems in using glaucoma medications. Ophthalmology. 2006;113(3):431–436. doi:10.1016/j.ophtha.2005.10.034
  • Higginbotham EJ. Considerations in glaucoma therapy: fixed combinations versus their component medications. Clin Ophthalmol. 2010;4:1–9.
  • Nguyen QH. Combination of brinzolamide and brimonidine for glaucoma and ocular hypertension: critical appraisal and patient focus. Patient Prefer Adherence. 2014;8:853–864. doi:10.2147/PPA
  • European Medicines Agency. Simbrinza® Summary of Product Characteristics. Switzerland: Novartis Pharma AG. Available from:: https://www.ema.europa.eu/documents/product-information/simbrinza-epar-product-information_en.pdf. Accessed November 5, 2018.
  • Food and Drug Administration. Simbrinza® prescribing information. Available from https://www.drugs.com/pro/simbrinza.html. Accessed August 5, 2018.
  • Gandolfi SA, Lim J, Sanseau AC, Parra Restrepo JC, Hamacher T. Randomized trial of brinzolamide/brimonidine versus brinzolamide plus brimonidine for open-angle glaucoma or ocular hypertension. Adv Ther. 2014;31(12):1213–1227. doi:10.1007/s12325-014-0168-y
  • Leske MC, Heijl A, Hussein M, et al. Factors for glaucoma progression and the effect of treatment: the early manifest glaucoma trial. Arch Ophthalmol. 2003;121(1):48–56. doi:10.1001/archopht.121.1.48
  • The Advanced Glaucoma Intervention Study (AGIS): 7. The relationship between control of intraocular pressure and visual field deterioration.The AGIS investigators. Am J Ophthalmol. 2000;130(4):429–440. doi:10.1016/S0002-9394(00)00538-9
  • Aung T, Laganovska G, Hernandez Paredes TJ, Branch JD, Tsorbatzoglou A, Goldberg I. Twice-daily brinzolamide/brimonidine fixed combination versus brinzolamide or brimonidine in open-angle glaucoma or ocular hypertension. Ophthalmology. 2014;121(12):2348–2355. doi:10.1016/j.ophtha.2014.06.022
  • Hollo G, Topouzis F, Fechtner RD. Fixed-combination intraocular pressure-lowering therapy for glaucoma and ocular hypertension: advantages in clinical practice. Expert Opin Pharmacother. 2014;15(12):1737–1747. doi:10.1517/14656566.2014.936850
  • Robin AL, Covert D. Does adjunctive glaucoma therapy affect adherence to the initial primary therapy? Ophthalmology. 2005;112(5):863–868. doi:10.1016/j.ophtha.2004.12.026
  • Schuman JS. Effects of systemic β-blocker therapy on the efficacy and safety of topical brimonidine and timolol. Ophthalmology. 2000;107(6):1171–1177. doi:10.1016/S0161-6420(00)00081-6
  • Waldock A, Snape J, Graham CM. Effects of glaucoma medications on the cardiorespiratory and intraocular pressure status of newly diagnosed glaucoma patients. Br J Ophthalmol. 2000;84(7):710–713. doi:10.1136/bjo.84.7.710
  • Javitt JC, Schiffman RM. Clinical success and quality of life with brimonidine 0.2% or timolol 0.5% used twice daily in glaucoma or ocular t hypertension: a randomized clinical trial. Brimonidine outcomes study group I. J Glaucoma. 2000;9(3):224–234. doi:10.1097/00061198-200006000-00005

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