The Role of Atopy in the Choroidal Profile of Keratoconus Patients

References

• Galvis V, Sherwin T, Tello A, Merayo J, Barrera R, Acera A. Keratoconus: an inflammatory disorder? Eye. 2015;29(7):843–859. doi:10.1038/eye.2015.63
   PubMed Web of Science ®Google Scholar
• Mas Tur V, MacGregor C, Jayaswal R, O’Brart D, Maycock N. A review of keratoconus: diagnosis, pathophysiology, and genetics. Surv Ophthalmol. 2017;62(6):770–783. doi:10.1016/j.survophthal.2017.06.009
   PubMed Web of Science ®Google Scholar
• Ionescu C, Corbu CG, Tanase C, et al. Inflammatory biomarkers profile as microenvironmental expression in keratoconus. Dis Markers. 2016;2016:1243819. doi:10.1155/2016/1243819
   PubMed Web of Science ®Google Scholar
• Shetty R, Ghosh A, Lim RR, et al. Elevated expression of matrix metalloproteinase-9 and inflammatory cytokines in keratoconus patients is inhibited by cyclosporine A. Invest Ophthalmol Vis Sci. 2015;56(2):738–750. doi:10.1167/iovs.14-14831
   PubMed Web of Science ®Google Scholar
• Lema I, Sobrino T, Durán JA, Brea D, Díez-Feijoo E. Subclinical keratoconus and inflammatory molecules from tears. Br J Ophthalmol. 2009;93(6):820–824. doi:10.1136/bjo.2008.144253
   PubMed Web of Science ®Google Scholar
• Sorkhabi R, Ghorbanihaghjo A, Taheri N, Ahoor MH. Tear film inflammatory mediators in patients with keratoconus. Int Ophthalmol. 2015;35(4):467–472. doi:10.1007/s10792-014-9971-3
   PubMed Web of Science ®Google Scholar
• Toprak I, Kucukatay V, Yildirim C, Kilic-Toprak E, Kilic-Erkek O. Increased systemic oxidative stress in patients with keratoconus. Eye. 2014;28(3):285–289.
   PubMed Web of Science ®Google Scholar
• Sobrino T, Regueiro U, Malfeito M, et al. Higher expression of toll-like receptors 2 and 4 in blood cells of keratoconus patiens. Sci Rep. 2017;7(1):12975. doi:10.1038/s41598-017-13525-7
   Web of Science ®Google Scholar
• Wisse RP, Kuiper JJ, Gans R, Imhof S, Radstake TR, Van der Lelij A. Cytokine expression in keratoconus and its corneal microenvironment: a systematic review. Ocul Surf. 2015;13(4):272–283. doi:10.1016/j.jtos.2015.04.006
   PubMed Web of Science ®Google Scholar
• Ferrari G, Rama P. The keratoconus enigma: a pathogenesis review. Ocul Surf. 2020. doi:10.1016/j.jtos.2020.03.006
   Web of Science ®Google Scholar
• Hashemi H, Heydarian S, Hooshmand E, et al. The prevalence and risk factors for keratoconus: a systematic review and meta-analysis. Cornea. 2020;39(2):263–270. doi:10.1097/ICO.0000000000002150
   PubMed Web of Science ®Google Scholar
• Ben-Eli H, Erdinest N, Solomon A. Pathogenesis and complications of chronic eye rubbing in ocular allergy. Curr Opin Allergy Clin Immunol. 2019;19(5):526–534. doi:10.1097/ACI.0000000000000571
   PubMed Web of Science ®Google Scholar
• Pinheiro-Costa J, Viana Pinto J, Perestrelo S, et al. Increased choroidal thickness in keratoconus patients: perspectives in the disease pathophysiology. J Ophthalmol. 2019;2019:2453931. doi:10.1155/2019/2453931
   Web of Science ®Google Scholar
• Gutierrez-Bonet R, Ruiz-Medrano J, Pena-Garcia P, et al. Macular choroidal thickening in keratoconus patients: Swept-Source Optical Coherence Tomography Study. Transl Vis Sci Technol. 2018;7(3):15. doi:10.1167/tvst.7.3.15
   Web of Science ®Google Scholar
• Bilgin B, Karadag AS. Choroidal thickness in keratoconus. Int Ophthalmol. 2020;40(1):135–140. doi:10.1007/s10792-019-01156-y
   PubMed Web of Science ®Google Scholar
• Steiner M, Esteban-Ortega MDM, Munoz-Fernandez S. Choroidal and retinal thickness in systemic autoimmune and inflammatory diseases: a review. Surv Ophthalmol. 2019;64(6):757–769. doi:10.1016/j.survophthal.2019.04.007
   PubMed Web of Science ®Google Scholar
• Fong AH, Li KK, Wong D. Choroidal evaluation using enhanced depth imaging spectral-domain optical coherence tomography in Vogt-Koyanagi-Harada disease. Retina. 2011;31(3):502–509. doi:10.1097/IAE.0b013e3182083beb
   PubMed Web of Science ®Google Scholar
• Jap A, Chee SP. The role of enhanced depth imaging optical coherence tomography in chronic Vogt-Koyanagi-Harada disease. Br J Ophthalmol. 2017;101(2):186–189. doi:10.1136/bjophthalmol-2015-308091
   PubMed Web of Science ®Google Scholar
• Ferreira CS, Beato J, Falcão MS, Brandão E, Falcão-Reis F, Carneiro ÂM. Choroidal thickness in multisystemic autoimmune diseases without ophthalmologic manifestations. Retina. 2017;37(3):529–535. doi:10.1097/IAE.0000000000001193
   PubMed Web of Science ®Google Scholar
• Torres T, Ferreira EO, Goncalo M, Mendes-Bastos P, Selores M, Filipe P. Update on atopic dermatitis. Acta Méd Port. 2019;32(9):606–613. doi:10.20344/amp.11963
   PubMed Web of Science ®Google Scholar
• Kim J, Kim BE, Leung DYM. Pathophysiology of atopic dermatitis: clinical implications. Allergy Asthma Proc. 2019;40(2):84–92. doi:10.2500/aap.2019.40.4202
   PubMed Web of Science ®Google Scholar
• Tong L, Corrales RM, Chen Z, et al. Expression and regulation of cornified envelope proteins in human corneal epithelium. Invest Ophthalmol Vis Sci. 2006;47(5):1938–1946. doi:10.1167/iovs.05-1129
   PubMed Web of Science ®Google Scholar
• Droitcourt C, Touboul D, Ged C, et al. A prospective study of filaggrin null mutations in keratoconus patients with or without atopic disorders. Dermatology. 2011;222(4):336–341. doi:10.1159/000328408
   Web of Science ®Google Scholar
• Yenigun A, Elbay A, Dogan R, Ozturan O, Ozdemir MH. The effect of allergic rhinitis with positive skin prick test on choroidal thickness. Eur Arch Otorhinolaryngol. 2017;274(6):2477–2481. doi:10.1007/s00405-017-4513-z
   Web of Science ®Google Scholar
• Gunay M, Dogru M, Celik G, Gunay BO. Swept-source optical coherence tomography analysis in asthmatic children under inhaled corticosteroid therapy. Cutan Ocul Toxicol. 2019;38(2):131–135. doi:10.1080/15569527.2018.1539009
   PubMed Web of Science ®Google Scholar
• Najmi H, Mobarki Y, Mania K, et al. The correlation between keratoconus and eye rubbing: a review. Int J Ophthalmol. 2019;12(11):1775–1781. doi:10.18240/ijo.2019.11.17
   PubMed Web of Science ®Google Scholar
• Bawazeer AM, Hodge WG, Lorimer B. Atopy and keratoconus: a multivariate analysis. Br J Ophthalmol. 2000;84(8):834–836. doi:10.1136/bjo.84.8.834
   PubMed Web of Science ®Google Scholar
• Di Martino E, Ali M, Inglehearn CF. Matrix metalloproteinases in keratoconus - too much of a good thing? Exp Eye Res. 2019;182:137–143. doi:10.1016/j.exer.2019.03.016
   PubMed Web of Science ®Google Scholar
• Greiner JV, Peace DG, Baird RS, Allansmith MR. Effects of eye rubbing on the conjunctiva as a model of ocular inflammation. Am J Ophthalmol. 1985;100(1):45–50. doi:10.1016/S0002-9394(14)74981-5
   PubMed Web of Science ®Google Scholar
• Zheng T, Yu J, Oh MH, Zhu Z. The atopic march: progression from atopic dermatitis to allergic rhinitis and asthma. Allergy Asthma Immunol Res. 2011;3(2):67–73. doi:10.4168/aair.2011.3.2.67
   PubMed Web of Science ®Google Scholar
• Gutierrez-Bonet R, Ruiz-Medrano J, Biarnés M, et al. Analysis of choroidal vascularity index in keratoconus patients using swept-source optical coherence tomography-based binarization techniques. J Ophthalmol. 2020;2020:1682463. doi:10.1155/2020/1682463
   Web of Science ®Google Scholar