Class II Human Leukocyte Antigen (HLA) and Susceptibility to Polypoidal Choroidal Vasculopathy in Afro-Caribbean Descent

References

• Yannuzzi LA, Sorenso J, Spaide RF, Lipson B. Idiopathic polypoidal choroidal vasculopathy. Retina. 1990;10:1–8. doi:10.1097/00006982-199010010-00001
   PubMed Web of Science ®Google Scholar
• Dansingani KK, Balaratnasingam C, Naysan J, Freund KB. En face imaging of pachychoroid spectrum disorders with swept-source optical coherence tomography. Retina. 2016;36:499–516. doi:10.1097/IAE.0000000000000742
   PubMed Web of Science ®Google Scholar
• Wang M, Zhou Y, Gao SS, et al. Evaluating polypoidal choroidal vasculopathy with optical coherence tomography angiography. Invest Ophthalmol Vis Sci. 2016;57:526–532. doi:10.1167/iovs.15-18955
   Web of Science ®Google Scholar
• Palkar AH, Khetan V. Polypoidal choroidal vasculopathy: an update on current management and review of literature. Taiwan J Ophthalmol. 2019;9:72–92.
   PubMedGoogle Scholar
• Machida S, Takahashi T, Gotoh N, Yoshimura N, Fujiwara T, Kurosaka D. Monozygotic twins with polypoidal choroidal vasculopathy. Clin Ophthalmol. 2010;4:793–800. doi:10.2147/OPTH.S11003
   PubMedGoogle Scholar
• Merle H, Donnio A, Richer R, Jean-Charles A. Familial bilateral polypoidal choroidal vasculopathy. Retin Cases Brief Rep. 2008;2:181–183. doi:10.1097/IAE.0b013e31802be7a3
   PubMedGoogle Scholar
• Stern RM, Zakov N, Zegarra H, Gutman FA. Multiple recurrent serosanguineous retinal pigment epithelial detachments in black women. Am J Ophthalmol. 1985;100:560–569. doi:10.1016/0002-9394(85)90682-8
   PubMed Web of Science ®Google Scholar
• Wong CW, Wong TY, Cheung CM. Polypoidal choroidal vasculopathy in Asians. J Clin Med. 2015;4:782–821. doi:10.3390/jcm4050782
   PubMed Web of Science ®Google Scholar
• Yannuzzi LA, Ciardella A, Spaide RF, Rabb M, Freund KB, Orlock DA. The expanding clinical spectrum of idiopathic polypoidal choroidal vasculopathy. Arch Ophthalmol. 1997;115:478–485. doi:10.1001/archopht.1997.01100150480005
   PubMedGoogle Scholar
• Ma L, Li Z, Liu K, et al. Association of genetic variants with polypoidal choroidal vasculopathy. A systematic review and updated meta-analysis. Ophthalmology. 2015;122:1854–1865. doi:10.1016/j.ophtha.2015.05.012
   PubMed Web of Science ®Google Scholar
• Penfold PL, Liew SC, Madigan MC, Provis JM. Modulation of major histocompatibility complex class II expression in retinas with age-related macular degeneration. Invest Ophthalmol Vis Sci. 1997;38:2125–2133.
   PubMed Web of Science ®Google Scholar
• Klein J, Sato A. The HLA system. First of two parts. N Engl J Med. 2000;343:702–709. doi:10.1056/NEJM200009073431006
   PubMed Web of Science ®Google Scholar
• Klein J, Sato A. The HLA system. Second of two parts. N Engl J Med. 2000;343:782–786. doi:10.1056/NEJM200009143431106
   PubMed Web of Science ®Google Scholar
• Stanton CM, Wright AF. Inflammatory biomarkers for AMD. Adv Exp Med Biol. 2014;801:251–257.
   PubMed Web of Science ®Google Scholar
• Hageman LPJ, Victor Chong NH, Johnson LV, Anderson DH, Mullins RF. An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch’s membrane interface in aging and age-related macular degeneration. Prog Retin Eye Res. 2001;20:705–732. doi:10.1016/S1350-9462(01)00010-6
   PubMed Web of Science ®Google Scholar
• Tan CS, Ngo WK, Chen JP, Tan NW, Lim TH. Everest study report 2: imaging and grading protocol, and baseline characteristics of a randomised controlled trial of polypoidal choroidal vasculopathy. Br J Ophthalmol. 2015;99:624–628. doi:10.1136/bjophthalmol-2014-305674
   PubMed Web of Science ®Google Scholar
• Japanese Study Group of Polypoidal Choroidal Vasculopathy. Criteria for diagnosis of polypoidal choroidal vasculopathy. Nippon Ganka Gakkai Zasshi. 2005;109:417–427.
   PubMedGoogle Scholar
• Marsh SG, Albert ED, Bodmer WF, et al. Nomenclature for factors of the HLA system, 2004. Hum Immunol. 2005;66:571–636. doi:10.1016/j.humimm.2005.02.002
   PubMed Web of Science ®Google Scholar
• Béra O, Césaire R, Quelvennec E, et al. HLA class I and class II allele and haplotype diversity in Martinicans. Tissue Antigens. 2001;57:200–207. doi:10.1034/j.1399-0039.2001.057003200.x
   PubMedGoogle Scholar
• Largen CE, Alper CA. The genetics of HLA-associated disease. Curr Opin Immunol. 2004;16:660–667. doi:10.1016/j.coi.2004.07.014
   PubMed Web of Science ®Google Scholar
• Klein R, Chou CF, Klein B, Zhang X, Meuer SM, Saaddine JB. Prevalence of age-related macular degeneration in the US population. Arch Ophthalmol. 2011;129:75–80. doi:10.1001/archophthalmol.2010.318
   PubMed Web of Science ®Google Scholar
• Villegas Becerril E, Gonzalez Fernadez R, Pérula Torres L, et al. HLA-B27 as predisposition factor to suffer age related macular degeneration. Cell Mol Immunol. 2009;6:303–307. doi:10.1038/cmi.2009.40
   PubMed Web of Science ®Google Scholar
• Jorgenson E, Melles RB, Hoffmann TJ, et al. Common coding variants in the HLA-DQB1 region confer susceptibility to age-related macular degeneration. Eur J Hum Genet. 2016;24:1049–1055. doi:10.1038/ejhg.2015.247
   PubMed Web of Science ®Google Scholar
• Goverdhan SV, Howell MW, Mullins RF, et al. Association of HLA class I and class II polymorphisms with age-related macular degeneration. Invest Ophthalmol Vis Sci. 2005;46:1726–1734. doi:10.1167/iovs.04-0928
   PubMed Web of Science ®Google Scholar
• Pappas D, Hollenbach J, Coleman AL, et al. HLA class II genotypes are not associated with age related macular degeneration in a case-control, population-based study. Hum Immunol. 2015;76:142–145. doi:10.1016/j.humimm.2015.01.010
   PubMed Web of Science ®Google Scholar
• Yuan D, Yang Q, Liu X, et al. Complement factor H Val62Ile variant and risk of age-related macular degeneration: a meta-analysis. Mol Vis. 2013;19:374–383.
   PubMed Web of Science ®Google Scholar
• Chen H, Liu K, Chen LJ, et al. Genetic associations in polypoidal choroidal vasculopathy: a systematic review and meta-analysis. Mol Vis. 2012;18:816–829.
   PubMed Web of Science ®Google Scholar
• Hayashi H, Yamashiro K, Gotoh N, et al. CFH and ARMS2 variations in age-related macular degeneration, polypoidal choroidal vasculopathy, and retinal angiomatous proliferation. Invest Ophthalmol Vis Sci. 2010;51:5914–5919. doi:10.1167/iovs.10-5554
   PubMed Web of Science ®Google Scholar
• Cheung CM, Laude A, Yeo I, et al. Systemic, ocular and genetic risk factors for age-related macular degeneration and polypoidal choroidal vasculopathy in Singaporeans. Sci Rep. 2017;7:41386. doi:10.1038/srep41386
   PubMed Web of Science ®Google Scholar
• Jones A, Kumar S, Zhang N, et al. Increased expression of multifunctional serine protease, HTRA1, in retinal pigment epithelium induces polypoidal choroidal vasculopathy in mice. Proc Natl Acad Sci USA. 2011;108:14578–14583. doi:10.1073/pnas.1102853108
   PubMed Web of Science ®Google Scholar
• Thorsby E, Lie BA. HLA associated genetic predisposition to autoimmune diseases: genes involved and possible mechanisms. Transpl Immunol. 2005;14:175–182. doi:10.1016/j.trim.2005.03.021
   PubMed Web of Science ®Google Scholar
• Abi-Hanna D, Wakefield D, Watkins S. HLA antigens in ocular tissues. I. In vivo expression in human eyes. Transplantation. 1988;45:610–613. doi:10.1097/00007890-198803000-00021
   PubMed Web of Science ®Google Scholar
• Dabil H, Kaplan HJ, Duffy BF, Phelan D, Mohanakumar T, Jaramillo A. Association of the HLA-DR15/HLA-DQ6 haplotype with development of choroidal neovascular lesions in presumed ocular histoplasmosis syndrome. Human Immunol. 2003;64:960–964. doi:10.1016/S0198-8859(03)00175-7
   PubMed Web of Science ®Google Scholar
• Borgersen NJ, Moller-Lorentzen T, Sorensen TL, Subhi Y. Association between C-reactive protein and polypoidal vasculopathy: a systematic review and meta-analysis. Acta Ophthalmol. 2021;99:470–477. doi:10.1111/aos.14655
   PubMed Web of Science ®Google Scholar
• Lafaut BA, Aisenbrey S, Van den Broecke C, Bartz-Schmidt KU, Heimann K. Polypoidal choroidal vasculopathy pattern in age-related macular degeneration: a clinicopathologic correlation. Retina. 2000;20:650–654. doi:10.1097/00006982-200011000-00010
   PubMed Web of Science ®Google Scholar
• Terasaki H, Miyake Y, Suzuki T, Nakamura M, Nagasaka T. Polypoidal choroidal vasculopathy treated with macular translocation: clinical pathological correlation. Br J Ophthalmol. 2002;86:321–327. doi:10.1136/bjo.86.3.321
   PubMed Web of Science ®Google Scholar
• Kumar S, Nakashizuka H, Jones A, et al. Proteolytic degradation and inflammation play critical roles in polypoidal choroidal vasculopathy. Am J Pathol. 2017;187:2841–2857. doi:10.1016/j.ajpath.2017.08.025
   PubMed Web of Science ®Google Scholar
• Yannuzzi LA, Wong DW, Sforzolini BS, et al. Polypoidal choroidal vasculopathy and neovascularized age-related macular degeneration. Arch Ophthalmol. 1999;117:1503–1510. doi:10.1001/archopht.117.11.1503
   PubMedGoogle Scholar