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Original Research

Prevalence of SARS-CoV-2 in Conjunctival Swab Samples Among Patients Presenting with Conjunctivitis During the COVID-19 Pandemic

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Pages 127-133 | Published online: 13 Jan 2022

References

  • World Health Organization. Report of the WHO-China joint mission on coronavirus disease 2019 (COVID-19); 2020. Available from: https://www.who.int/publications/i/item/report-of-the-who-china-joint-mission-on-coronavirus-disease-2019-(covid-19). Accessed August 11, 2021.
  • Wang D, Hu B, Hu C, et al. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China. JAMA. 2020;323:1061–1069. doi:10.1001/jama.2020.1585
  • Loffredo L, Pacella F, Pacella E, et al. Conjunctivitis and COVID-19: a meta-analysis. J Med Virol. 2020;92:1413–1414. doi:10.1002/jmv.25938
  • Guan W, Ni Z, Hu Y, et al. Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med. 2020;382:1708–1720. doi:10.1056/NEJMoa2002032
  • Colavita F, Lapa D, Carletti F, et al. SARS-CoV-2 isolation from ocular secretions of a patient with COVID-19 in Italy with prolonged viral RNA detection. Ann Intern Med. 2020;173:242–243. doi:10.7326/M20-1176
  • Chen L, Liu M, Zhang Z, et al. Ocular manifestations of a hospitalised patient with confirmed 2019 novel coronavirus disease. Br J Ophthalmol. 2020;104:748–751. doi:10.1136/bjophthalmol-2020-316304
  • Li JO, Lam DSC, Chen Y, Ting DSW. Novel coronavirus disease 2019 (COVID-19): the importance of recognising possible early ocular manifestation and using protective eyewear. Br J Ophthalmol. 2020;104:297–298. doi:10.1136/bjophthalmol-2020-315994
  • Wu P, Duan F, Luo C, et al. Characteristics of ocular findings of patients with coronavirus disease 2019 (COVID-19) in Hubei Province, China. JAMA Ophthalmol. 2020;138:575–578. doi:10.1001/jamaophthalmol.2020.1291
  • Xia J, Tong J, Liu M, et al. Evaluation of coronavirus in tears and conjunctival secretions of patients with SARS-CoV-2 infection. J Med Virol. 2020;92:589–594. doi:10.1002/jmv.25725
  • Scalinci SZ, Trovato Battagliola E. Conjunctivitis can be the only presenting sign and symptom of COVID-19. IDCases. 2020;20:e00774. doi:10.1016/j.idcr.2020.e00774
  • Ying NY, Idris NS, Muhamad R, Ahmad I. Coronavirus disease 2019 presenting as conjunctivitis. Korean J Fam Med. 2021;42:487–490. doi:10.4082/kjfm.20.0090
  • Corman VM, Landt O, Kaiser M, et al. Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR. Euro Surveill. 2020;25:2000045. doi:10.2807/1560-7917.ES.2020.25.3.2000045
  • Zhang X, Chen X, Chen L, et al. The evidence of SARS-CoV-2 infection on ocular surface. Ocul Surf. 2020;18:360–362. doi:10.1016/j.jtos.2020.03.010
  • Cavalleri M, Brambati M, Starace V, et al. Ocular features and associated systemic findings in SARS-CoV-2 infection. Ocul Immunol Inflamm. 2020;28:916–921. doi:10.1080/09273948.2020.1781198
  • Ya Y, Yanping S, Ming Y, et al. Novel coronavirus pneumonia combined with conjunctivitis: three cases report. Chin J Exp Ophthalmol. 2020;38:242–244.
  • Qu J, Xie H, Zhang M. Evidence of SARS-CoV-2 transmission through the ocular route. Clin Ophthalmol. 2021;15:687–696. doi:10.2147/OPTH.S295283
  • Ankita AK, Saxena SK. COVID-19: an ophthalmological update. In: Saxena SK, editor. Coronavirus Disease 2019 (COVID-19): Epidemiology, Pathogenesis, Diagnosis, and Therapeutics. Singapore: Springer Singapore; 2020:81–93.
  • Deng W, Bao L, Gao H, et al. Ocular conjunctival inoculation of SARS-CoV-2 can cause mild COVID-19 in rhesus macaques. Nat Commun. 2020;11:4400. doi:10.1038/s41467-020-18149-6
  • Dutescu RM, Banasik P, Schildgen O, et al. Detection of coronavirus in tear samples of hospitalized patients with confirmed SARS-CoV-2 from oropharyngeal swabs. Cornea. 2021;40:348–350. doi:10.1097/ICO.0000000000002562
  • Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395:497–506. doi:10.1016/S0140-6736(20)30183-5
  • Zhou Y, Duan C, Zeng Y, et al. Ocular findings and proportion with conjunctival SARS-COV-2 in COVID-19 patients. Ophthalmology. 2020;127:982–983. doi:10.1016/j.ophtha.2020.04.028
  • Garcia-Zalisnak D, Rapuano C, Sheppard JD, Davis AR. Adenovirus ocular infections: prevalence, pathology, pitfalls, and practical pointers. Eye Contact Lens. 2018;44(Suppl 1):S1–S7. doi:10.1097/ICL.0000000000000226
  • Azari AA, Barney NP. Conjunctivitis: a systematic review of diagnosis and treatment. JAMA. 2013;310:1721–1729. doi:10.1001/jama.2013.280318
  • Singh RB, Liu L, Anchouche S, et al. Ocular redness - I: etiology, pathogenesis, and assessment of conjunctival hyperemia. Ocul Surf. 2021;21:134–144. doi:10.1016/j.jtos.2021.05.003
  • Pekel G, Azman E, Pekel E, et al. Preocular tear film tests in acute hemorrhagic conjunctivitis caused by coxsackievirus A24 variant. Turk J Ophthalmol. 2012;42:186–189.
  • Wright PW, Strauss GH, Langford MP. Acute hemorrhagic conjunctivitis. Am Fam Physician. 1992;45:173–178.
  • Li W, Wong S, Li F, et al. Animal origins of the severe acute respiratory syndrome coronavirus: insight from ACE2-S-protein interactions. J Virol. 2006;80:4211–4219. doi:10.1128/JVI.80.9.4211-4219.2006
  • Bielory BP, O’Brien TP, Bielory L. Management of seasonal allergic conjunctivitis: guide to therapy. Acta Ophthalmol. 2012;90:399–407. doi:10.1111/j.1755-3768.2011.02272.x
  • Napoli PE, Nioi M, Fossarello M. The “Quarantine Dry Eye”: the lockdown for coronavirus disease 2019 and its implications for ocular surface health. Risk Manag Healthc Policy. 2021;14:1629–1636. doi:10.2147/RMHP.S277067
  • Saldanha IJ, Petris R, Makara M, Channa P, Akpek EK. Impact of the COVID-19 pandemic on eye strain and dry eye symptoms. Ocul Surf. 2021;22:38–46. doi:10.1016/j.jtos.2021.06.004
  • Prescott CR. Increased screen time and dry eye: another complication of COVID-19. Eye Contact Lens. 2021;47:433. doi:10.1097/ICL.0000000000000820
  • Kaufman HE. Adenovirus advances: new diagnostic and therapeutic options. Curr Opin Ophthalmol. 2011;22:290–293. doi:10.1097/ICU.0b013e3283477cb5
  • Napoli PE, Mangoni L, Gentile P, Braghiroli M, Fossarello M. A panel of broad-spectrum antivirals in topical ophthalmic medications from the drug repurposing approach during and after the coronavirus disease 2019 era. J Clin Med. 2020;9:2441. doi:10.3390/jcm9082441
  • Napoli PE, Nioi M, d’Aloja E, Fossarello M. The ocular surface and the coronavirus disease 2019: does a dual “ocular route” exist? J Clin Med. 2020;9:1269. doi:10.3390/jcm9051269