202
Views
0
CrossRef citations to date
0
Altmetric
Original Research

A Plant-Derived Antioxidant Supplement Prevents the Loss of Retinal Ganglion Cells in the Retinas of NMDA-Injured Mice

, , , ORCID Icon, , , , & show all
Pages 823-832 | Published online: 18 Mar 2022

References

  • Quigley HA. Number of people with glaucoma worldwide. Br J Ophthalmol. 1996;80(5):389–393. doi:10.1136/bjo.80.5.389
  • Weinreb RN, Tee Khaw P. Primary open-angle glaucoma. Lancet. 2004;363(9422):1711–1720. doi:10.1016/S0140-6736(04)16257-0
  • Yokoyama Y, Maruyama K, Konno H, et al. Characteristics of patients with primary open angle glaucoma and normal tension glaucoma at a university hospital: a cross-sectional retrospective study. BMC Res Notes. 2015;8(1):1–8. doi:10.1186/s13104-015-1339-x
  • Nakazawa T. Ocular blood flow and influencing factors for glaucoma. Asia Pacific J Ophthalmol. 2016;5(1):38–44. doi:10.1097/APO.0000000000000183
  • Tanito M, Kaidzu S, Takai Y, Ohira A. Status of Systemic Oxidative Stresses in Patients with Primary Open-Angle Glaucoma and Pseudoexfoliation Syndrome. PLoS One. 2012;7(11):1–7. doi:10.1371/journal.pone.0049680
  • Himori N, Kunikata H, Shiga Y, et al. The association between systemic oxidative stress and ocular blood flow in patients with normal-tension glaucoma. Graefe’s Arch Clin Exp Ophthalmol. 2016;254(2):333–341. doi:10.1007/s00417-015-3203-z
  • Alvarado J, Murphy C, Polansky J, Juster R. Age-related changes in trabecular meshwork cellularity. Investig Ophthalmol Vis Sci. 1981;21(5):714–727.
  • Ferreira SM, Lerner SF, Brunzini R, Evelson PA, Llesuy SF. Oxidative stress markers in aqueous humor of glaucoma patients. Am J Ophthalmol. 2004;137(1):62–69. doi:10.1016/S0002-9394(03)00788-8
  • Harada T, Harada C, Nakamura K, et al. The potential role of glutamate transporters in the pathogenesis of normal tension glaucoma. J Clin Invest. 2007;117(7):1763–1770. doi:10.1172/JCI30178
  • Inokuchi Y, Imai S, Nakajima Y, et al. Edaravone, a free radical scavenger, protects against retinal damage in vitro and in vivo. J Pharmacol Exp Ther. 2009;329(2):687–698. doi:10.1124/jpet.108.148676
  • Noro T, Namekata K, Kimura A, et al. Spermidine promotes retinal ganglion cell survival and optic nerve regeneration in adult mice following optic nerve injury. Cell Death Dis. 2015;6(4):1–9. doi:10.1038/cddis.2015.93
  • Kanamori A, Catrinescu MM, Mahammed A, Gross Z, Levin LA. Neuroprotection against superoxide anion radical by metallocorroles in cellular and murine models of optic neuropathy. J Neurochem. 2010;114(2):488–498. doi:10.1111/j.1471-4159.2010.06781.x
  • Levkovitch-Verbin H, Harris-Cerruti C, Groner Y, Wheeler LA, Schwartz M, Yoles E. RGC death in mice after optic nerve crush injury: oxidative stress and neuroprotection. Investig Ophthalmol Vis Sci. 2000;41(13):4169–4174.
  • Himori N, Yamamoto K, Maruyama K, et al. Critical role of Nrf2 in oxidative stress-induced retinal ganglion cell death. J Neurochem. 2013;127(5):669–680. doi:10.1111/jnc.12325
  • Coyle JT, Puttfarcken P. Puttfarcken JTC and P. Oxidative Stress, Glutamate, and Neurodegenerative Disorders. Science. 1993;262(5134):689–695. doi:10.1126/science.7901908
  • Yasuda M, Shimura M, Kunikata H, et al. Relationship of skin autofluorescence to severity of retinopathy in type 2 diabetes. Curr Eye Res. 2015;40(3):338–345. doi:10.3109/02713683.2014.918152
  • Hashimoto K, Kunikata H, Yasuda M, et al. The relationship between advanced glycation end products and ocular circulation in type 2 diabetes. J Diabetes Complications. 2016;30(7):1371–1377. doi:10.1016/j.jdiacomp.2016.04.024
  • Smith W, Mitchell P, Webb K, Leeder SR. Dietary antioxidants and age-related maculopathy: the Blue Mountains Eye Study. Ophthalmology. 1999;106(4):761–767. doi:10.1016/S0161-6420(99)90164-1
  • Maekawa S, Sato K, Fujita K, et al. The neuroprotective effect of hesperidin in NMDA-induced retinal injury acts by suppressing oxidative stress and excessive calpain activation. Sci Rep. 2017;7(1):1–13. doi:10.1038/s41598-017-06969-4
  • Sato K, Sato T, Ohno-Oishi M, et al. CHOP Deletion and Anti-Neuroinflammation Treatment With Hesperidin Synergistically Attenuate NMDA Retinal Injury in Mice. Exp Eye Res. 2021;213((February):108826):108826. doi:10.1016/j.exer.2021.108826
  • Yamamoto K, Maruyama K, Himori N, et al. The novel Rho kinase (ROCK) inhibitor K-115: a new candidate drug for neuroprotective treatment in glaucoma. Invest Ophthalmol Vis Sci. 2014;55(11):7126–7136. doi:10.1167/iovs.13-13842
  • Sato K, Li S, Gordon WC, et al. Receptor interacting protein kinase-mediated necrosis contributes to cone and rod photoreceptor degeneration in the retina lacking interphotoreceptor retinoid-binding protein. J Neurosci. 2013;33(44):17458–17468. doi:10.1523/JNEUROSCI.1380-13.2013
  • Sato K, Shiga Y, Nakagawa Y, et al. Ecel1 knockdown with an AAV2-mediated CRISPR/Cas9 system promotes optic nerve damage-induced RGC death in the mouse retina. Investig Ophthalmol Vis Sci. 2018;59(10):3943–3951. doi:10.1167/iovs.18-23784
  • Kwong JMK, Caprioli J, Piri N. RNA binding protein with multiple splicing: a new marker for retinal ganglion cells. Investig Ophthalmol Vis Sci. 2010;51(2):1052–1058. doi:10.1167/iovs.09-4098
  • Rodriguez AR, de Sevilla Müller LP, Brecha NC. The RNA binding protein RBPMS is a selective marker of ganglion cells in the mammalian retina. J Comp Neurol. 2014;522(6):1411–1443. doi:10.1002/cne.23521
  • Yokoyama Y, Maruyama K, Yamamoto K, et al. The role of calpain in an in vivo model of oxidative stress-induced retinal ganglion cell damage. Biochem Biophys Res Commun. 2014;451(4):510–515. doi:10.1016/j.bbrc.2014.08.009
  • Shareef S, Sawada A, Neufeld AH. Isoforms of nitric oxide synthase in the optic nerves of rat eyes with chronic moderately elevated intraocular pressure. Investig Ophthalmol Vis Sci. 1999;40(12):2884–2891.
  • Izzotti A, Bagnis A, Saccà SC. The role of oxidative stress in glaucoma. Mutat Res. 2006;612(2):105–114. doi:10.1016/j.mrrev.2005.11.001
  • Himori N, Kunikata H, Kawasaki R, et al. The association between skin autofluorescence and mean deviation in patients with open-angle glaucoma. Br J Ophthalmol. 2017;101(2):233–238. doi:10.1136/bjophthalmol-2016-309504
  • Asano Y, Himori N, Kunikata H, et al. Age- and sex-dependency of the association between systemic antioxidant potential and glaucomatous damage. Sci Rep. 2017;7(1):1–8. doi:10.1038/s41598-017-08624-4
  • Yang X, Hondur G, Tezel G. Antioxidant treatment limits neuroinflammation in experimental glaucoma. Investig Ophthalmol Vis Sci. 2016;57(4):2344–2354. doi:10.1167/IOVS.16-19153
  • Lee D, Shim MS, Kim KY, et al. Coenzyme Q10 inhibits glutamate excitotoxicity and oxidative stress-mediated mitochondrial alteration in a mouse model of glaucoma. Investig Ophthalmol Vis Sci. 2014;55(2):993–1005. doi:10.1167/iovs.13-12564
  • Kang JH, Willett WC, Rosner BA, Buys E, Wiggs JL, Pasquale LR. Association of dietary nitrate intake with primary open-angle glaucoma: a prospective analysis from the nurses’ health study and health professionals follow-up study. JAMA Ophthalmol. 2016;134(3):294–303. doi:10.1001/jamaophthalmol.2015.5601
  • Lee J, Sohn SW, Kee C. Effect of ginkgo biloba extract on visual field progression in normal tension glaucoma. J Glaucoma. 2013;22(9):780–784. doi:10.1097/IJG.0b013e3182595075
  • Wu HY, Tomizawa K, Oda Y, et al. Critical Role of Calpain-mediated Cleavage of Calcineurin in Excitotoxic Neurodegeneration. J Biol Chem. 2004;279(6):4929–4940. doi:10.1074/jbc.M309767200
  • Sakamoto Y, Nakajima T, Fukiage C, et al. Involvement of calpain isoforms in ischemia-reperfusion injury in rat retina. Curr Eye Res. 2000;21(1):571–580. doi:10.1076/0271-3683(200007)2111-ZFT571
  • McKernan DP, Guerin MB, O’Brien CJ, Cotter TG. A key role for calpains in retinal ganglion cell death. Investig Ophthalmol Vis Sci. 2007;48(12):5420–5430. doi:10.1167/iovs.07-0287
  • Sanvicens N, Cotter TG. Ceramide is the key mediator of oxidative stress-induced apoptosis in retinal photoreceptor cells. J Neurochem. 2006;98(5):1432–1444. doi:10.1111/j.1471-4159.2006.03977.x
  • Chiu K, Tim TL, Li WWY, Caprioli J, Kwong JMK. Calpain and N-methyl-D-aspartate (NMDA)-induced excitotoxicity in rat retinas. Brain Res. 2005;1046(1–2):207–215. doi:10.1016/j.brainres.2005.04.016
  • Volbracht C, Chua BT, Ng CP, Bahr BA, Hong W, Li P. The critical role of calpain versus caspase activation in excitotoxic injury induced by nitric oxide. J Neurochem. 2005;93(5):1280–1292. doi:10.1111/j.1471-4159.2005.03122.x
  • Yamauchi M, Tsuruma K, Imai S, et al. Crocetin prevents retinal degeneration induced by oxidative and endoplasmic reticulum stresses via inhibition of caspase activity. Eur J Pharmacol. 2011;650(1):110–119. doi:10.1016/j.ejphar.2010.09.081
  • Mohamad MHN, Abu IF, Fazel MF, et al. Neuroprotection Against NMDA-Induced Retinal Damage by Philanthotoxin-343 Involves Reduced Nitrosative Stress. Front Pharmacol. 2021;12(December):1–11. doi:10.3389/fphar.2021.798794
  • Jangra A, Kasbe P, Pandey SN, et al. Hesperidin and Silibinin Ameliorate Aluminum-Induced Neurotoxicity: modulation of Antioxidants and Inflammatory Cytokines Level in Mice Hippocampus. Biol Trace Elem Res. 2015;168(2):462–471. doi:10.1007/s12011-015-0375-7
  • Sharma P, Kumari S, Sharma J, Purohit R, Singh D. Hesperidin Interacts With CREB-BDNF Signaling Pathway to Suppress Pentylenetetrazole-Induced Convulsions in Zebrafish. Front Pharmacol. 2021;11:(January):1–12. doi:10.3389/fphar.2020.607797
  • Rosa-Falero C, Torres-Rodríguez S, Jordán CC, et al. Modulation of PTZ induced seizures by Citrus aurantium in zebrafish: role of NMDA and metabotropic glutamate receptors. Front Pharmacol. 2014;5:(DEC):1–11. doi:10.3389/fphar.2014.00284
  • Kuehn S, Rodust C, Stute G, et al. Concentration-Dependent Inner Retina Layer Damage and Optic Nerve Degeneration in a NMDA Model. J Mol Neurosci. 2017;63(3–4):283–299. doi:10.1007/s12031-017-0978-x
  • Menze ET, Tadros MG, Abdel-Tawab AM, Khalifa AE. Potential neuroprotective effects of hesperidin on 3-nitropropionic acid-induced neurotoxicity in rats. Neurotoxicology. 2012;33(5):1265–1275. doi:10.1016/j.neuro.2012.07.007
  • See-Lok H, Poon C-Y, Lin C, Yan T. Inhibition of β-amyloid Aggregation By Albiflorin, Aloeemodin And Neohesperidin And Their Neuroprotective Effect On Primary Hippocampal Cells Against β-amyloid Induced Toxicity. Curr Alzheimer Res. 2015;12(5):424–433. doi:10.2174/1567205012666150504144919
  • Ohba T, Ishisaka M, Tsujii S, et al. Crocetin protects ultraviolet A-induced oxidative stress and cell death in skin in vitro and in vivo. Eur J Pharmacol. 2016;789:244–253. doi:10.1016/j.ejphar.2016.07.036
  • Zheng S, Qian Z, Sheng L, Wen N. Crocetin attenuates atherosclerosis in hyperlipidemic rabbits through inhibition of LDL oxidation. J Cardiovasc Pharmacol. 2006;47(1):70–76. doi:10.1097/01.fjc.0000194686.11712.02
  • Razali N, Aziz AA, Lim CY, Junit SM. Investigation into the effects of antioxidant-rich extract of Tamarindus indica leaf on antioxidant enzyme activities, oxidative stress and gene expression profiles in HepG2 cells. PeerJ. 2015;2015(10):865. doi:10.7717/peerj.1292
  • Dreyer EB, Zurakowski D, Schumer RA, Podos SM, Lipton SA. Elevated glutamate levels in the vitreous body of humans and monkeys with glaucoma. Arch Ophthalmol. 1996;114:299. doi:10.1001/archopht.1996.01100130295012
  • Jin H, Zhu B, Liu X, Jin J, Zou H. Metabolic characterization of diabetic retinopathy: an 1H-NMR-based metabolomic approach using human aqueous humor. J Pharm Biomed Anal. 2019;174:414–421. doi:10.1016/j.jpba.2019.06.013
  • Himori N, Yanagimachi MI, Omodaka K, et al. The effect of dietary antioxidant supplementation in patients with glaucoma. Clin Ophthalmol. 2021;15:2293–2300. doi:10.2147/OPTH.S314288