References
- ParkinDMBrayFFerlayJPisaniPGlobal cancer statistics, 2002CA Cancer J Clin20055527410815761078
- LiYSunDLDuanYNAssociation of functional polymorphisms in MMPs genes with gastric cardia adenocarcinoma and esophageal squamous cell carcinoma in high incidence region of North ChinaMol Biol Rep201037119720519562509
- BoyerBVallesAMEdmeNInduction and regulation of epithelial-mesenchymal transitionsBiochem Pharmacol20006081091109911007946
- GuarionMEpithelial-mesenchymal transition and tumour invasionInt J Biochem Cell Biol200739122153216017825600
- LeeJMDedharSKalluriRThompsonEWThe epithelial-mesenchymal transition: new insights in signaling, development, and diseaseJ Cell Biol2006172797398116567498
- ThieryJPAcloqueHHuangRYNietoMAEpithelial-mesenchymal transitions in development and diseaseCell2009139587189019945376
- XuJLamouilleSDerynckRTGF-beta-induced epithelial to mesenchymal transitionCell Res200919215617219153598
- IkushimaHMiyazonoKTGF signalling: a complex web in cancer progressionNat Rev Cancer201010641542420495575
- QuanJElhousinyMJohnsonNWGaoJTransforming growth factor-beta1 treatment of oral cancer induces epithelial-mesenchymal transition and promotes bone invasion via enhanced activity of osteoclastsClin Exp Metastasis201330565967023378237
- ReichlPHaiderCGrubingerMMikulitsWTGF-beta in epithelial to mesenchymal transition and metastasis of liver carcinomaCurr Pharm Des201218274135414722630087
- EllenriederVHendlerSFBoeckWTransforming growth factor beta1 treatment leads to an epithelial-mesenchymal transdifferentiation of pancreatic cancer cells requiring extracellular signal-regulated kinase 2 activationCancer Res200161104222422811358848
- ZhangHYLiSSTransforming growth factor-β1 induced epithelial-mesenchymal transition in human esophageal squamous cell carcinoma via PTEN/PI3K signaling pathwayOncol Rep20143252134214225175594
- PangLLiQWeiCTGF-β1/Smad signaling pathway regulates epithelial-to-mesenchymal transition in esophageal squamous cell carcinoma: in vitro and clinical analyses of cell lines and nomadic Kazakh patients from northwest Xinjiang, ChinaPLoS One2014912e11230025464508
- KatsunoYLamouilleSDerynckRTGF-β signaling and epithelial–mesenchymal transition in cancer progressionCurr Opin Oncol2013251768423197193
- SunLDiamondMEOttavianoAJJosephMJAnanthanarayanVMunshiHGTransforming growth factor-{beta}1 promotes matrix metalloproteinase-9-mediated oral cancer invasion through Snail expressionMol Cancer Res200861102018234959
- JosephMJDangi-GarimellaSShieldsMASlug is a down-stream mediator of transforming growth factor-beta1-induced matrix metalloproteinase-9 expression and invasion of oral cancer cellsJ Cell Biochem2009108372673619681038
- SinpitaksakulSNPimkhaokhamASanchavanakitNPavasantPTGF-β1 induced MMP-9 expression in HNSCC cell lines via Smad/MLCK pathwayBiochem Biophy Res Commun20083714713718
- StamenkovicIExtracellular matrix remodelling: the role of matrix metalloproteinasesJ Pathol2003200444846412845612
- ChaudharyAKPandyaSGhoshKNadkarniAMatrix metalloproteinase and its drug targets therapy in solid and hematological malignancies: an overviewMutat Res2013753172323370482
- KapoorCVaidyaSWadhwanVHiteshKaurGPathakASeesaw of matrix metalloproteinases (MMPs)J Cancer Res Ther2016121283527072206
- RadiskyDCLevyDDLittlepageLERac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instabilityNature2005436704712312716001073
- OrlichenkoLSRadiskyDCMatrix metalloproteinases stimulate epithelial-mesenchymal transition during tumor developmentClin Exp Metastasis200825659360018286378
- YangCCZhuLFXuXHNingTYYeJHLiuLKMembrane Type 1 Matrix Metalloproteinase induces an epithelial to mesenchymal transition and cancer stem cell-like properties in SCC9 cellsBMC Cancer20131317123548172
- PangLLiQLiSMembrane type 1-matrix metalloproteinase induces epithelial-to-mesenchymal transition in esophageal squamous cell carcinoma: observations from clinical and in vitro analysesSci Rep2015622179
- IllmanSALehtiKKeski-OjaJLohiJEpilysin (MMP-28) induces TGF-beta mediated epithelial to mesenchymal transition in lung carcinoma cellsJ Cell Sci2006119pt 183856386516940349
- ChangCJChaoCHXiaWp53 regulates epithelial-mesenchymal transition and stem cell properties through modulating miRNAsNat Cell Biol201113331732321336307
- XiangJFuXRanWWangZGrhl2 reduces invasion and migration through inhibition of TGFβ-induced EMT in gastric cancerOncogenesis201761e28428067907
- XuanXZengQLiYAkt-mediated transforming growth factor-β1-induced epithelial-mesenchymal transition in cultured human esophageal squamous cancer cellsCancer Gene Ther201421623824524874843
- CuiLSongJWuLRole of Annexin A2 in the EGF-induced epithelial-mesenchymal transition in human CaSki cellsOncol Lett201713137738328123570
- KimJKongJChangHKimHKimAEGF induces epithelialmesenchymal transition through phospho-Smad2/3-Snail signaling pathway in breast cancer cellsOncotarget2016751850218503227829223
- LuoMHouLLiJVEGF/NRP-1axis promotes progression of breast cancer via enhancement of epithelial-mesenchymal transition and activation of NF-κB and β-cateninCancer Lett2016373111126805761
- JiaoDWangJLuWCurcumin inhibited HGF-induced EMT and angiogenesis through regulating c-Met dependent PI3K/Akt/mTOR signaling pathways in lung cancerMol Ther Oncolytics201631601827525306
- WendtMKSchiemannWPTherapeutic targeting of the focal adhesion complex prevents oncogenic TGF-beta signaling and metastasisBreast Cancer Res2009115R6819740433
- GomesLRTerraLFWailemannRAMLabriolaLSogayarMCTGF-β1 modulates the homeostasis between MMPs and MMP inhibitors through p38 MAPK and ERK1/2 in highly invasive breast cancer cellsBMC Cancer2012122622260435
- LiJYangBZhouQAutophagy promotes hepatocellular carcinoma cell invasion through activation of epithelial–mesenchymal transitionCarcinogenesis20133461343135123430956
- TanTKZhengGHsuTTMacrophage matrix metalloproteinase-9 mediates epithelial-mesenchymal transition in vitro in murine renal tubular cellsAm J Pathol201017631256127020075196
- TianMNeilJRSchiemannWPTransforming growth factor-beta and the hallmarks of cancerCell Signal201123695196220940046
- QinGLuoMChenJReciprocal activation between MMP-8 and TGF-β1 stimulates EMT and malignant progression of hepatocellular carcinomaCancer Lett20163741859526872724
- HanahanDWeinbergRAHallmarks of cancer: the next generationCell201114464667421376230
- KessenbrockKPlaksVWerbZMatrix metalloproteinases: regulators of the tumor microenvironmentCell20101411526720371345
- GialeliCTheocharisADKaramanosNKRoles of matrix metalloproteinases in cancer progression and their pharmacological targetingFEBS J20112781162721087457
- LochterAGalosySMuschlerJFreedmanNWerbZBissellMJMatrix metalloproteinase stromelysin-1 triggers a cascade of molecular alterations that leads to stable epithelial-to-mesenchymal conversion and a premalignant phenotype in mammary epithelial cellsJ Cell Biol19971397186118729412478
- NoeVFingletonBJacobsKRelease of an invasion promoter E-cadherin fragment by matrilysin and stromelysin-1J Cell Sci2001114pt 111111811112695
- SymowiczJAdleyBPGleasonKJEngagement of collagen-binding integrins promotes matrix metalloproteinase-9-dependent E-cadherin ectodomain shedding in ovarian carcinoma cellsCancer Res20076752030203917332331
- MaretzkyTReissKLudwigAADAM10 mediates E-cadherin shedding and regulates epithelial cell-cell adhesion, migration, and beta-catenin translocationProc Natl Acad Sci U S A2005102269182918715958533
- CovingtonMDBurghardtRCParrishARIschemia-induced cleavage of cadherins in NRK cells requires MT1-MMP (MMP-14)Am J Physiol Renal Physiol20062901F43F5116077081
- YuQStamenkovicICell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesisGenes Dev200014216317610652271
- KarsdalMALarsenLEngsigMTMatrix metalloproteinase-dependent activation of latent transforming growth factor-beta controls the conversion of osteoblasts into osteocytes by blocking osteoblast apoptosisJ Biol Chem200227746440614406712226090
- MuDCambierSFjellbirkelandLThe integrin alpha(v)beta8 mediates epithelial homeostasis through MT1-MMP-dependent activation of TGF-beta1J Cell Biol2002157349350711970960
- DangeloMSarmentDPBillingsPCPacificiMActivation of transforming growth factor beta in chondrocytes undergoing endochondral ossificationJ Bone Miner Res200116122339234711760850