References
- LeitaoALCostaMCEnguitaFJUnzippers, resolvers and sensors: a structural and functional biochemistry tale of RNA helicasesInt J Mol Sci20151622269229325622248
- DeckertJHartmuthKBoehringerDProtein composition and electron microscopy structure of affinity-purified human spliceosomal B complexes isolated under physiological conditionsMol Cell Biol200626145528554316809785
- MerzCUrlaubHWillCLLuhrmannRProtein composition of human mRNPs spliced in vitro and differential requirements for mRNP protein recruitmentRNA200713111612817095540
- YedavalliVSNeuveutCChiYHKleimanLJeangKTRequirement of DDX3 DEAD box RNA helicase for HIV-1 Rev-RRE export functionCell2004119338139215507209
- LaiMCLeeYHTarnWYThe DEAD-box RNA helicase DDX3 associates with export messenger ribonucleoproteins as well as tip-associated protein and participates in translational controlMol Biol Cell20081993847385818596238
- PekJWKaiTDEAD-box RNA helicase Belle/DDX3 and the RNA interference pathway promote mitotic chromosome segregationProc Natl Acad Sci U S A201110829120071201221730191
- KasimVWuSTairaKMiyagishiMDetermination of the role of DDX3 a factor involved in mammalian RNAi pathway using an shRNA-expression libraryPLoS One201383e5944523527197
- LeeCSDiasAPJedrychowskiMPatelAHHsuJLReedRHuman DDX3 functions in translation and interacts with the translation initiation factor eIF3Nucleic Acids Res200836144708471818628297
- LiYWangHWangZInducible resistance of tumor cells to tumor necrosis factor-related apoptosis-inducing ligand receptor 2-mediated apoptosis by generation of a blockade at the death domain functionCancer Res200666178520852816951164
- SunMSongLLiYZhouTJopeRSIdentification of an antiapoptotic protein complex at death receptorsCell Death Differ200815121887190018846110
- ShihJWWangWTTsaiTYKuoCYLiHKWu LeeYHCritical roles of RNA helicase DDX3 and its interactions with eIF4E/PABP1 in stress granule assembly and stress responseBiochem J2012441111912921883093
- BolGMVesunaFXieMTargeting DDX3 with a small molecule inhibitor for lung cancer therapyEMBO Mol Med20157564866925820276
- Heerma van VossMRVesunaFTrumpiKIdentification of the DEAD box RNA helicase DDX3 as a therapeutic target in colorectal cancerOncotarget2015629283122832626311743
- BotlaguntaMVesunaFMironchikYOncogenic role of DDX3 in breast cancer biogenesisOncogene200827283912392218264132
- ChenHHYuHIChoWCTarnWYDDX3 modulates cell adhesion and motility and cancer cell metastasis via Rac1-mediated signaling pathwayOncogene201534212790280025043297
- TopisirovicISiddiquiNLapointeVLMolecular dissection of the eukaryotic initiation factor 4E (eIF4E) export-competent RNPEMBO J20092881087109819262567
- XieMVesunaFBotlaguntaMNZ51, a ring-expanded nucleoside analog, inhibits motility and viability of breast cancer cells by targeting the RNA helicase DDX3Oncotarget2015630299012991326337079
- WilkyBAKimCMcCartyGRNA helicase DDX3: a novel therapeutic target in Ewing sarcomaOncogene201635202574258326364611
- KodachLLWiercinskaEde MirandaNFThe bone morphogenetic protein pathway is inactivated in the majority of sporadic colorectal cancersGastroenterology200813451332134118471510
- MoelansCBde WegerRAvan BloklandMTHER-2/neu amplification testing in breast cancer by multiplex ligation-dependent probe amplification in comparison with immunohistochemistry and in situ hybridizationCell Oncol200931111019096145
- CareyLAPerouCMLivasyCARace, breast cancer subtypes, and survival in the carolina breast cancer studyJAMA2006295212492250216757721
- VermeulenJFvan de VenRAErcanCNuclear Kaiso expression is associated with high grade and triple-negative invasive breast cancerPLoS One201275e3786422662240
- Wet medisch-wetenschappelijk onderzoek met mensen, WMO [The Medical Research Involving Human Subjects Act]Burgerlijk WetboekDutch governmentthe Netherlands1998 Dutch
- van DiestPJNo consent should be needed for using leftover body material for scientific purposes. ForBMJ20023257365648651
- AngusAGDalrympleDBoulantSRequirement of cellular DDX3 for hepatitis C virus replication is unrelated to its interaction with the viral core proteinJ Gen Virol201091Pt 112213219793905
- BudcziesJKlauschenFSinnBVCutoff Finder: a comprehensive and straightforward Web application enabling rapid biomarker cutoff optimizationPLoS One2012712e5186223251644
- NoskeAWeichertWNiesporekSExpression of the nuclear export protein chromosomal region maintenance/exportin 1/Xpo1 is a prognostic factor in human ovarian cancerCancer200811281733174318306389
- KudoNMatsumoriNTaokaHLeptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue in the central conserved regionProc Natl Acad Sci U S A199996169112911710430904
- IshizawaJKojimaKHailNJrTabeYAndreeffMExpression, function, and targeting of the nuclear exporter chromosome region maintenance 1 (CRM1) proteinPharmacol Ther2015153253526048327
- FornerodMOhnoMYoshidaMMattajIWCRM1 is an export receptor for leucine-rich nuclear export signalsCell1997906105110609323133
- AskjaerPRosendahlRKjemsJNuclear export of the DEAD box An3 protein by CRM1 is coupled to An3 helicase activityJ Biol Chem200027516115611156810766770
- BolGMXieMRamanVDDX3, a potential target for cancer treatmentMol Cancer201514118826541825
- SamalSKRoutraySVeeramachaneniGKDashRBotlaguntaMKetorolac salt is a newly discovered DDX3 inhibitor to treat oral cancerSci Rep20155998225918862
- KoshioJKagamuHNozakiKDEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked is an immunogenic target of cancer stem cellsCancer Immunol Immunother201362101619162823974721
- YedavalliVSZhangNCaiHRing expanded nucleoside analogues inhibit RNA helicase and intracellular human immunodeficiency virus type 1 replicationJ Med Chem200851165043505118680273
- RadiMFalchiFGarbelliADiscovery of the first small molecule inhibitor of human DDX3 specifically designed to target the RNA binding site: towards the next generation HIV-1 inhibitorsBioorg Med Chem Lett20122252094209822300661
- MahboobiSHJavanpourAAMofradMRThe interaction of RNA helicase DDX3 with HIV-1 Rev-CRM1-RanGTP complex during the HIV replication cyclePLoS One2015102e011296925723178
- SuCYLinTCLinYFDDX3 as a strongest prognosis marker and its downregulation promotes metastasis in colorectal cancerOncotarget2015621186021861226087195
- ChungGGProvostEKielhornEPCharetteLASmithBLRimmDLTissue microarray analysis of beta-catenin in colorectal cancer shows nuclear phospho-beta-catenin is associated with a better prognosisClin Cancer Res20017124013402011751495
- JarbouiMABidoiaCWoodsENucleolar protein trafficking in response to HIV-1 Tat: rewiring the nucleolusPLoS One2012711e4870223166591
- Yasuda-InoueMKurokiMAriumiYDistinct DDX DEAD-box RNA helicases cooperate to modulate the HIV-1 Rev functionBiochem Biophy Res Commun20134344803808
- AndersenJSLyonCEFoxAHDirected proteomic analysis of the human nucleolusCurr Biol200212111111790298
- DerenziniMMontanaroLTrereDWhat the nucleolus says to a tumour pathologistHistopathology200954675376219178588
- RuggeroDPandolfiPPDoes the ribosome translate cancer?Nat Rev Cancer20033317919212612653
- GeisslerRGolbikRPBehrensSEThe DEAD-box helicase DDX3 supports the assembly of functional 80S ribosomesNucleic Acids Res201240114998501122323517
- WangTBirsoyKHughesNWIdentification and characterization of essential genes in the human genomeScience201535062641096110126472758
- HeinNHannanKMGeorgeAJSanijEHannanRDThe nucleolus: an emerging target for cancer therapyTrends Mol Med2013191164365423953479
- SenissarMLe SauxABelgareh-TouzeNAdamCBanroquesJTannerNKThe DEAD-box helicase Ded1 from yeast is an mRNP cap-associated protein that shuttles between the cytoplasm and nucleusNucleic Acids Res20144215100051002225013175
- HaukGBowmanGDFormation of a trimeric Xpo1-Ran[GTP]-Ded1 exportin complex modulates ATPase and helicase activities of Ded1PLoS One2015106e013169026120835
- FröhlichARojas-ArayaBPereira-MontecinosCDEAD-box RNA helicase DDX3 connects CRM1-dependent nuclear export and translation of the HIV-1 unspliced mRNA through its N-terminal domainBiochim Biophy Acta201618595719730
- NassarHQureshiHVolkanadsayNVisscherDClinicopathologic analysis of solid papillary carcinoma of the breast and associated invasive carcinomasAm J Surg Pathol200630450150716625097