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Original Research

Real-world usage and clinical outcomes of alectinib among post-crizotinib progression anaplastic lymphoma kinase positive non-small-cell lung cancer patients in the USA

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Pages 75-82 | Published online: 22 Dec 2017

References

  • National Cancer InstituteSEER stat fact sheets: Lung and bronchus cancer Available from: http://seer.cancer.gov/statfacts/html/lungb.htmlAccessed November 18, 2015
  • RamalingamSBelaniCSystemic chemotherapy for advanced non-small cell lung cancer: recent advances and future directionsOncologist200813Suppl 151318263769
  • O’BryantCLWengerSDKimMThompsonLACrizotinib: a new treatment option of ALK-positive non-small cell lung cancerAnn Pharmacother201347218919723386065
  • RadzikowskaERoszkowski-SlizKChabowskiMGlazPInfluence of delays in diagnosis and treatment on survival in small cell lung cancer patientsAdv Exp Med Biol201378835536223835998
  • DempkeWCTargeted therapy for NSCLC-A double-edged Sword?Anticancer Res20153552503251225964523
  • ShepherdFSecond-line chemotherapy for non-small cell lung cancerExpert Rev Anticancer Ther20033143544212934656
  • ScagliottiGVParikhPvon PawelJPhase III study comparing cisplatin plus gemcitabine with cisplatin plus pemetrexed in chemotherapy-naïve patients with advanced-stage non-small cell lung cancerJ Clin Oncol200826213543345118506025
  • DempkeWCSutoTReckMTargeted therapies for non-small cell lung cancerLung Cancer201067325727419914732
  • MaWGilliganBMYuanJLiTCurrent status and perspectives in translational biomarker research for PD-1/PD-L1 immune checkpoint blockade therapyJ Hematol Oncol2016914727234522
  • DholariaBHammondWShredersALouYEmerging therapeutic agents for lung cancerJ Hematol Oncol20169113827938382
  • DiggsLPHsuehECUtility of PD-L1 immunohistochemistry assays for predicting PD-1/PD-L1 inhibitor responseBiomark Res2017511228331612
  • MinguetJSmithKHBramlagePTargeted therapies for treatment of non-small cell lung cancer – recent advances and future perspectivesInt J Cancer2016138112549256126537995
  • SolomonBVarella-GarciaMCamidgeDRALK gene rearrangements: a new therapeutic target in a molecularly defined subset of non-small cell lung cancerJ Thorac Oncol20094121450145420009909
  • GainorJFVargheseAMOuSHALK rearrangements are mutually exclusive with mutations in EGFR or KRAS: an analysis of 1,683 patients with non-small cell lung cancerClin Cancer Res201319154273428123729361
  • CasaluceFSgambatoAMaionePALK inhibitors: a new targeted therapy in the treatment of advanced NSCLCTarg Oncol2013815567
  • ChristensenJGZouHYArangoMECytoreductive antitumor activity of PF-2341066, a novel inhibitor of anaplastic lymphoma kinase and c-Met, in experimental models of anaplastic large-cell lymphomaMol Cancer Ther2007612 Pt 13314332218089725
  • KwakELBangYJCamidgeDRAnaplastic lymphoma kinase inhibition in non-small-cell lung cancerN Engl J Med2010363181693170320979469
  • CamidgeDRBangYJKwakELActivity and safety of crizotinib in patients with ALK-positive non-small-cell lung cancer: updated results from a phase 1 studyLancet Oncol201213101011101922954507
  • ShawATKimDWNakagawaKCrizotinib vs chemotherapy in advanced ALK-positive lung cancerN Engl J Med20133682385239423724913
  • SolomonBJMokTKimDWPROFILE 1014 InvestigatorsFirst-line crizotinib vs chemotherapy in ALK-positive lung cancerN Engl J Med20143712132167217725470694
  • ToyokawaGSetoTALK inhibitors: what is the best way to treat patients with ALK+ non-small-cell lung cancer?Clin Lung Cancer201415531331924984564
  • KatayamaRShawATKhanTMMechanisms of acquired crizotinib resistance in ALK-rearranged lung cancersSci Transl Med20124120120ra17
  • DoebeleRCPillingABAisnerDLMechanisms of resistance to crizotinib in patients with ALK gene rearranged non-small cell lung cancerClin Cancer Res20121851472148222235099
  • WeickhardtAJScheierBBurkeJMLocal ablative therapy of oligoprogressive disease prolongs disease control by tyrosine kinase inhibitors in oncogene addicted non-small cell lung cancerJ Thorac Oncol20127121807181423154552
  • WuJSavoojiJLiuDSecond- and third-generation ALK inhibitors for non-small cell lung cancerJ Hematol Oncol201691926951079
  • IragavarapuCMustafaMAkinleyeANovel ALK inhibitors in clinical use and developmentJ Hematol Oncol201581725888090
  • KodamaTHasegawaMTakanashiKSakuraiYKondohOSakamotoHAntitumor activity of the selective ALK inhibitor alectinib in models of intracranial metastasesCancer Chemother Pharmacol20147451023102825205428
  • OuSHAhnJSDe PetrisLAlectinib in crizotinib-refractory ALK-rearranged non-small-cell lung cancer: a Phase II Global StudyJ Clin Oncol201634766166826598747
  • ShawATGandhiLGadgeelSstudy investigatorsAlectinib in ALK-positive, crizotinib-resistant, non-small-cell lung cancer: a single-group,multicentre, phase 2 trialLancet Oncol201617223424226708155
  • YangJCOuSIDe PetrisLPooled systemic efficacy and safety data from two phase II studies (NP28673 and NP28761) of alectinib in ALK-positive non-small-cell lung cancer (NSCLC)J Thorac Oncol201712101552156028689043
  • GadgeelSMGandhiLRielyGJSafety and activity of alectinib against systemic disease and brain metastases in patients with crizotinib-resistant ALK-rearranged non-small-cell lung cancer (AF-002JG): results from the dose-finding portion of a phase 1/2 studyLancet Oncol201415101119112825153538
  • BendalyESasaneMZhangJSwallowEMacalaladARPatelDDiverse characteristics of the ALK+ NSCLC patients in the United StatesPoster presented at: The 16th World Conference on Lung CancerSeptember 2015Denver, CO
  • BettsKSongJGuoJWongWRaveloASchulzMReal-world treatment patterns and brain metastases development in ALK-positive non-small cell lung cancerPoster presented at: The Association of Managed Care Pharmacist (AMCP) Annual Managed Care and Specialty Pharmacy Annual MeetingApril 2016San Fransisco, CA
  • GuérinASasaneMZhangJBrain metastases in patients with ALK+ non-small cell lung cancer: clinical symptoms, treatment patterns and economic burdenJ Med Econ201518431232225565443
  • DoebeleRCLuXSumeyCOncogene status predicts patterns of metastatic spread in treatment-naïve nonsmall cell lung cancerCancer2012118184502451122282022
  • RangachariDYamaguchiNVanderLaanPABrain metastases in patients with EGFR-mutated or ALK-rearranged non-small-cell lung cancersLung Cancer201588110811125682925
  • ToyokawaGSetoTTakenoyamaMIchinoseYInsights into brain metastasis in patients with ALK+ lung cancer: is the brain truly a sanctuary?Cancer Metastasis Rev201534479780526342831
  • Barnholtz-SloanJSSloanAEDavisFGVigneauFDLaiPSawayaREIncidence proportions of brain metastases in patients diagnosed (1973 to 2001) in the metropolitan detroit cancer surveillance systemJ Clin Oncol200422142865287215254054
  • JenaATanejaSTalwarVSharmaJBMagnetic resonance (MR) patterns of brain metastasis in lung cancer patients: correlation of imaging findings with symptomJ Thorac Oncol20083214014418303434
  • BaikCSChamberlainMCChowLQTargeted therapy for brain metastases in EGFR-mutated and ALK-rearranged non-small-cell lung cancerJ Thorac Oncol20151091268127826107553