74
Views
16
CrossRef citations to date
0
Altmetric
Original Research

IL-21-secreting hUCMSCs combined with miR-200c inhibit tumor growth and metastasis via repression of Wnt/β-catenin signaling and epithelial–mesenchymal transition in epithelial ovarian cancer

, , , , , , & show all
Pages 2037-2050 | Published online: 10 Apr 2018

References

  • HoCMChangSFHsiaoCCChienTYShihDTIsolation and characterization of stromal progenitor cells from ascites of patients with epithelial ovarian adenocarcinomaJ Biomed Sci2012192322330345
  • AyhanAGultekinMDursunPMetastatic lymph node number in epithelial ovarian carcinoma, does it have any clinical significance?Gynecol Oncol2008108242843218249232
  • MeserveEEKMirkovicJConnerJRFrequency of “incidental” serous tubal intraepithelial carcinoma (STIC) in women without a history of or genetic risk factor for high-grade serous carcinoma: A six-year studyGynecol Oncol20171461697328479065
  • Parrish-NovakJDillonSRNelsonAInterleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte functionNature20004086808576311081504
  • UgaiSShimozatoOKawamuraKExpression of the interleukin-21 gene in murine colon carcinoma cells generates systemic immunity in the inoculated hostsCancer Gene Ther2003101077177814502230
  • DouJChenGWangJPreliminary study on mouse interleukin-21 application in tumor gene therapyCell Mol Immunol20041646146616293216
  • VenkatasubramanianSCheekatlaSPaidipallyPIL-21-dependent expansion of memory-like NK cells enhances protective immune responses against Mycobacterium tuberculosisMucosal Immunol20171041031104227924822
  • ZhaoFDouJWangJInvestigation on the anti-tumor efficacy by expression of GPI-anchored mIL-21 on the surface of B16F10 cells in C57BL/6 miceImmunobiology201021528910019457579
  • KimSMLimJYParkSIGene therapy using TRAIL-secreting human umbilical cord blood-derived mesenchymal stem cells against intracranial gliomaCancer Res2008689614962319047138
  • Alvarez-MercadoAIGarcia-MediavillaMVSanchez-CamposSDeleterious effect of human umbilical cord blood mononuclear cell transplantation on thioacetamide-induced chronic liver damage in ratsCell Transplant200918101069107919650975
  • HuWWangJDouJAugmenting therapy of ovarian cancer efficacy by secreting IL-21 human umbilical cord blood stem cells in nude miceCell Transplant201120566968021054951
  • BakXYLamDHYangJHuman embryonic stem cell-derived mesenchymal stem cells as cellular delivery vehicles for prodrug gene therapy of glioblastomaHum Gene Ther201122111365137721425958
  • RyuCHParkSHParkSAGene therapy of intracranial glioma using interleukin 12-secreting human umbilical cord blood-derived mesenchymal stem cellsHum Gene Ther201122673374321261460
  • ChangYSOhWChoiSJHuman umbilical cord blood-derived mesenchymal stem cells attenuate hyperoxia-induced lung injury in neonatal ratsCell Transplant200918886988619500472
  • BrackenCPGregoryPAKolesnikoffNA double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transitionCancer Res200868197846785418829540
  • CittellyDMDimitrovaIHoweENRestoration of miR-200c to ovarian cancer reduces tumor burden and increases sensitivity to paclitaxelMol Cancer Ther201211122556256523074172
  • ChenDZhangYWangJMicroRNA-200c overexpression inhibits tumorigenicity and metastasis of CD117+CD44+ovarian cancer stem cells by regulating epithelial-mesenchymal transitionJ Ovarian Res2013615023842108
  • WangHSHungSCPengSTMesenchymal stem cells in the Wharton’s jelly of the human umbilical cordStem Cells20042271330133715579650
  • ZhangYWangJRenMGene therapy of ovarian cancer using IL-21-secreting human umbilical cord mesenchymal stem cells in nude miceJ Ovarian Res20147824444073
  • DouJNiYHeXDecreasing lncRNA HOTAIR expression inhibits human colorectal cancer stem cellsAm J Transl Res2016819810827069543
  • ShenBChuESZhaoGPPARgamma inhibits hepatocellular carcinoma metastases in vitro and in miceBr J Cancer201210691486149422472882
  • MarshallJTranswell(®)invasion assaysMethods Mol Biol20117699711021748672
  • WangXZhaoFHeXCombining TGF-β1 knockdown and miR200c administration to optimize antitumor efficacy of B16F10/GPI-IL-21 vaccineOncotarget2015614124931250425895132
  • DouJHeXFCaoWHOverexpression of microRNA-200c in CD44+CD133+CSCS inhibits the cellular migratory and invasion as well as tumorigenicity in miceCell Mol Biol (Noisy-le-grand)2013Suppl 59OL1861OL186824120113
  • RosenbergSASherryRMMortonKETumor progression can occur despite the induction of very high levels of self/tumor antigen-specific CD8+T cells in patients with melanomaJ Immunol200517596169617616237114
  • LecoeurHFévrierMGarciaSRivièreYGougeonMLA novel flow cytometric assay for quantitation and multiparametric characterization of cell-mediated cytotoxicityJ Immunol Methods20012531–217718711384679
  • ChenJWangJZhangYObservation of ovarian cancer stem cell behavior and investigation of potential mechanisms of drug resistance in three-dimensional cell cultureJ Biosci Bioeng2014118221422224684961
  • DouJLiuPZhangXCellular response to gene expression profiles of different hepatitis C virus core protein in Huh-7 cell line with microarray analysisJ Nanosci Nanotechnol2005581230123516193983
  • ShiSRLiuCYoungLTaylorCDevelopment of an optimal antigen retrieval protocol for immunohistochemistry of retinoblastoma protein (pRB) in formalin fixed, paraffin sections based on comparison of different methodsBiotech Histochem200782630130918097796
  • HuWWangJHeXHuman umbilical blood mononuclear cell-derived mesenchymal stem cells serve as interleukin-21 gene delivery vehicles for epithelial ovarian cancer therapy in nude miceBiotechnol Appl Biochem201158639740422172102
  • Di CarloEComesAOrengoAMIL-21 induces tumor rejection by specific CTL and IFN-gamma-dependent CXC chemokines in syngeneic miceJ Immunol200417231540154714734732
  • DouJTangQZhaoFComparison of immune responses induced in mice by vaccination with DNA vaccine constructs expressing mycobacterial antigen 85A and interleukin-21 and Bacillus Galmette-GuérinImmunol Invest200837211312718300037
  • WangJZhouDHeXEffect of downregulated β-catenin on cell proliferative activity, the sensitivity to chemotherapy drugs and tumorigenicity of ovarian cancer cellsCell Mol Biol (Noisy-le-grand)201157 SupplOL1606OL161322000491
  • DouJHeXLiuYEffect of downregulation of ZEB1 on vimentin expression, tumour migration and tumourigenicity of melanoma B16F10 cells and CSCsCell Biol Int201438445246124339410
  • ShangSHuaFHuZWThe regulation of β-catenin activity and function in cancer: therapeutic opportunitiesOncotarget2017820339723398928430641
  • SunJYangXZhangRGOLPH3 induces epithelial-mesenchymal transition via Wnt/β-catenin signaling pathway in epithelial ovarian cancerCancer Med20176483484428332316
  • LiRDongTHuCLuJDaiJLiuPSalinomycin repressed the epithelial-mesenchymal transition of epithelial ovarian cancer cells via downregulating Wnt/β-cateninpathwayOnco Targets Ther2017101317132528280366
  • IkramMSNeillGWReglGGLI2 is expressed in normal human epidermis and BCC and induces GLI1 expression by binding to its promoterJ Invest Dermatol200412261503150915175043
  • DennlerSAndreJAlexakiIInduction of sonic hedgehog mediators by transforming growth factor-beta: Smad3-dependent activation of Gli2 and Gli1 expression in vitro and in vivoCancer Res200767146981698617638910
  • ThieryJPAcloqueHHuangRYNietoMAEpithelial-mesenchymal transitions in development and diseaseCell2009139587189019945376
  • KoutsakiMLibraMSpandidosDAZaravinosAThe miR-200 family in ovarian cancerOncotarget2017839666296664029029543