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Original Research

RRM1 expression and the clinicopathological characteristics of patients with non-small cell lung cancer treated with gemcitabine

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Pages 5579-5589 | Published online: 07 Sep 2018

References

  • SiegelRLMillerKDJemalAStatisticsCCA Cancer J Clin2017201767730
  • WoodSLPernemalmMCrosbiePAWhettonADThe role of the tumor-microenvironment in lung cancer-metastasis and its relationship to potential therapeutic targetsCancer Treat Rev201440455856624176790
  • BrayFRenJSMasuyerEFerlayJGlobal estimates of cancer prevalence for 27 sites in the adult population in 2008Int J Cancer201313251133114522752881
  • Paz-AresLde MarinisFDediuMMaintenance therapy with pemetrexed plus best supportive care versus placebo plus best supportive care after induction therapy with pemetrexed plus cisplatin for advanced non-squamous non-small-cell lung cancer (PARAMOUNT): a double-blind, phase 3, randomised controlled trialLancet Oncol201213324725522341744
  • GeorgouliasVAndroulakisNKotsakisADocetaxel versus docetaxel plus gemcitabine as front-line treatment of patients with advanced non-small cell lung cancer: a randomized, multicenter phase III trialLung Cancer2008591576317765354
  • ToschiLCappuzzoFGemcitabine for the treatment of advanced nonsmall cell lung cancerOnco Targets Ther2009220921720616908
  • ReaumeMNLeighlNBMittmannNEconomic analysis of a randomized phase III trial of gemcitabine plus vinorelbine compared with cisplatin plus vinorelbine or cisplatin plus gemcitabine for advanced non-small-cell lung cancer (Italian GEMVIN3/NCIC CTG BR14 trial)Lung Cancer201382111512023962449
  • PitterleDMKimYCJolicoeurEMCaoYO’BriantKCBeplerGLung cancer and the human gene for ribonucleotide reductase subunit M1 (RRM1)Mamm Genome199910991692210441745
  • BeplerGGautamAMcintyreLMPrognostic significance of molecular genetic aberrations on chromosome segment 11p15.5 in non-small-cell lung cancerJ Clin Oncol20022051353136011870179
  • BergmanAMEijkPPRuiz van HaperenVWIn vivo induction of resistance to gemcitabine results in increased expression of ribonucleotide reductase subunit M1 as the major determinantCancer Res200565209510951616230416
  • OguriTAchiwaHSatoSThe determinants of sensitivity and acquired resistance to gemcitabine differ in non-small cell lung cancer: a role of ABCC5 in gemcitabine sensitivityMol Cancer Ther2006571800180616891466
  • BeplerGKusmartsevaISharmaSRRM1 modulated in vitro and in vivo efficacy of gemcitabine and platinum in non-small-cell lung cancerJ Clin Oncol200624294731473716966686
  • RosellRDanenbergKDAlberolaVRibonucleotide Reductase Messenger RNA Expression and Survival in Gemcitabine/Cisplatin-Treated Advanced Non-Small Cell Lung Cancer PatientsClinical Cancer Research20041041318132514977831
  • RosellRFelipETaronMGene expression as a predictive marker of outcome in stage IIB-IIIA-IIIB non-small cell lung cancer after induction gemcitabine-based chemotherapy followed by resectional surgeryClin Cancer Res20041012 Pt 24215S4219S15217961
  • SouglakosJBoukovinasITaronMRibonucleotide reductase subunits M1 and M2 mRNA expression levels and clinical outcome of lung adenocarcinoma patients treated with docetaxel/gemcitabineBr J Cancer200898101710171518414411
  • JordheimLPSèvePTrédanODumontetCThe ribonucleotide reductase large subunit (RRM1) as a predictive factor in patients with cancerLancet Oncol201112769370221163702
  • CeppiPVolanteMNovelloSERCC1 and RRM1 gene expressions but not EGFR are predictive of shorter survival in advanced non-small-cell lung cancer treated with cisplatin and gemcitabineAnn Oncol200617121818182516980606
  • DersimonianRLairdNMeta-analysis in clinical trialsControl Clin Trials1986731771883802833
  • MantelNHaenszelWStatistical aspects of the analysis of data from retrospective studies of diseaseJ Natl Cancer Inst195922471974813655060
  • BeggCBMazumdarMOperating characteristics of a rank correlation test for publication biasBiometrics1994504108811017786990
  • ChabnerBALongoDLCancer Chemotherapy and Biotherapy: Principles and PracticePhiladelphia, PALippincott Williams & Wilkins2011
  • GautamALiZRBeplerGRRM1-induced metastasis suppression through PTEN-regulated pathwaysOncogene200322142135214212687015
  • GoanYGZhouBHuEMiSYenYOverexpression of ribonucleotide reductase as a mechanism of resistance to 2,2-difluorodeoxycytidine in the human KB cancer cell lineCancer Res199959174204420710485455
  • DavidsonJDMaLFlagellaMGeeganageSGelbertLMSlapakCAAn increase in the expression of ribonucleotide reductase large subunit 1 is associated with gemcitabine resistance in non-small cell lung cancer cell linesCancer Res200464113761376615172981
  • AoyamaTMiyagiYMurakawaMClinical implications of ribonucleotide reductase subunit M1 in patients with pancreatic cancer who undergo curative resection followed by adjuvant chemotherapy with gemcitabineOncol Lett20171353423343028521448
  • MlakRKrawczykPCiesielkaMThe relationship between RRM1 gene polymorphisms and effectiveness of gemcitabine-based first-line chemotherapy in advanced NSCLC patientClin Transl Oncol201618991592426650486
  • MausMKMackPCAstrowSHHistology-related associations of ERCC1, RRM1, and TS biomarkers in patients with non-small-cell lung cancer: implications for therapyJ Thorac Oncol20138558258623470290
  • ZhaoLPXueCZhangJWExpression of RRM1 and its association with resistancy to gemcitabine-based chemotherapy in advanced nasopharyngeal carcinomaChin J Cancer2012311047648322692073
  • GuoNZhangWZhangBEGFR and K-RAS mutations and ERCC1, TUBB3, TYMS, RRM1 and EGFR mRNA expression in non-small cell lung cancer: Correlation with clinical response to gefitinib or chemotherapyMol Clin Oncol2015351123112826623063
  • XingXWangLXiaoXAnalysis of RRM1 expression in advanced NSCLC and its relationship with chemotherapyChin J Cancer Prev Treat20142118931896
  • ZengFShanLInvestigation about expression of RRM1 (ribonucleotide reductase M1) and the correlation with Gemcitabine-based chemotherapy sensitivity in the advanced non-small cell lung cancerJournal of Taishan Medical College200930570573
  • ZhaoHZhangHduYGuXPrognostic significance of BRCA1, ERCC1, RRM1, and RRM2 in patients with advanced non-small cell lung cancer receiving chemotherapyTumour Biol20143512126791268825227663
  • Xian-JunFXiu-GuangQLiZERCC1 and BRCA1 mRNA expression predicts the clinical outcome of non-small cell lung cancer receiving platinum-based chemotherapyPak J Med Sci201430348849224948964
  • WangLMengLWangXWMaGYChenJHExpression of RRM1 and RRM2 as a novel prognostic marker in advanced non-small cell lung cancer receiving chemotherapyTumour Biol20143531899190624155212
  • LiangJGJinZYGaoXDPredictive role of RRM1 and BRCA1 mRNA expression on the clinical outcome of advanced non-small cell lung cancerGenet Mol Res20141335292529825078585
  • DongXHaoYWeiYYinQduJZhaoXResponse to first-line chemotherapy in patients with non-small cell lung cancer according to RRM1 expressionPLoS One201493e9232024647522
  • Jian-WeiBYi-MinMYu-XiaSShi-QingLExpression levels of ERCC1 and RRM1 mRNA and clinical outcome of advanced non-small cell lung cancerPak J Med Sci20132951158116124353711
  • SuCZhouSZhangLERCC1, RRM1 and BRCA1 mRNA expression levels and clinical outcome of advanced non-small cell lung cancerMed Oncol20112841411141720467918
  • WuGQLiuNNXueXLMultiplex real-time PCR for RRM1, XRCC1, TUBB3 and TS mRNA for prediction of response of non-small cell lung cancer to chemoradiotherapyAsian Pac J Cancer Prev201415104153415824935362
  • WangXZhaoJYangLPositive expression of ERCC1 predicts a poorer platinum-based treatment outcome in Chinese patients with advanced non-small-cell lung cancerMed Oncol201027248449019488864
  • GuoQZWangJBaiHHigh expression of ERCC1 is a poor prognostic factor in Chinese patients with non-small cell lung cancer receiving cisplatin-based therapyChin J Cancer Res2010224296302
  • LeeJJMaengCHBaekSKThe immunohistochemical overex-pression of ribonucleotide reductase regulatory subunit M1 (RRM1) protein is a predictor of shorter survival to gemcitabine-based chemotherapy in advanced non-small cell lung cancer (NSCLC)Lung Cancer201070220521020223551
  • MaKLiEGuoYWangXSunHShaoGRelationship between the efficacy of gemcitabine/cisplatin adjuvant chemotherapy and RRM1 protein expression in postoperative NSCLC patientsZhonghua Zhong Liu Za Zhi201436750551025327655
  • JiangBTuCHeWYangCZhaoJAnalysis of RRM1 expression and efficacy of gemcitabine in advanced non-small cell lung cancerCancer Research on Prevention and Treatment2013406871
  • LinLZhangXHuJHuangFLiWAnalysis of the relationship between RM1 mRNA expression level and efficacy of gemcitabine maintenance therapy for advanced non-small cell lung cancerThe Practical Journal of Cancer2016312225
  • VilmarACSantoni-RugiuESorensenJBPredictive impact of RRM1 protein expression on vinorelbine efficacy in NSCLC patients randomly assigned in a chemotherapy phase III trialAnn Oncol201324230931423038758
  • XuCWWangGWangWLAssociation between epidermal growth factor receptor mutations and the expression of excision repair cross-complementing protein 1 and ribonucleotide reductase subunit M1 mRNA in patients with non-small cell lung cancerExp Ther Med20159388088425667646
  • LiuDNakashimaNNakanoJCustomized Adjuvant Chemotherapy Based on Biomarker Examination May Improve Survival of Patients Completely Resected for Non-small-cell Lung CancerAnticancer Res20173752501250728476819
  • LiuHWangHYangJRRM1 Expression and Efficacy Analysis of Gemcitabine in Advanced Non-small Cell Lung CancerPract Prevent Med2009161114
  • LiLLiuXCorrelation of expression of ERCC1/RRM1 with cisplatin combined with gemcitabine chemotherapy sensitivity and prognosis in non-small cell lung cancerBull Acad Mil Med Sci201034265268
  • YangZLiuDChenFChenJTanSLinSThe effect of RRM1 expression in lung cancer tissues for predict chemotherapeutic effect of GPChin J Oncol Prev Treat20091124126
  • ZhangGBChenJWangLRRRM1 and ERCC1 expression in peripheral blood versus tumor tissue in gemcitabine/carboplatin-treated advanced non-small cell lung cancerCancer Chemother Pharmacol20126951277128722302408
  • BeplerGSommersKECantorAClinical efficacy and predictive molecular markers of neoadjuvant gemcitabine and pemetrexed in resectable non-small cell lung cancerJ Thorac Oncol20083101112111818827606
  • BoukovinasIPapadakiCMendezPTumor BRCA1, RRM1 and RRM2 mRNA expression levels and clinical response to first-line gemcitabine plus docetaxel in non-small-cell lung cancer patientsPLoS One2008311e369519002265
  • GaoZHanBShenJGuAZhongHRelations between RRM1 protein expression levels and effects of gemcitabine and cisplatin chemotherapy in advanced non-small cell lung cancer patientsZhongguo Fei Ai Za Zhi201114434034421496433
  • RosellRScagliottiGDanenbergKDTranscripts in pretreatment biopsies from a three-arm randomized trial in metastatic non-small-cell lung cancerOncogene200322233548355312789263
  • ReynoldsCObasajuCSchellMJRandomized phase III trial of gemcitabine-based chemotherapy with in situ RRM1 and ERCC1 protein levels for response prediction in non-small-cell lung cancerJ Clin Oncol200927345808581519884554
  • CampRLChungGGRimmDLAutomated subcellular localization and quantification of protein expression in tissue microarraysNat Med20028111323132812389040
  • ZhengZChenTLiXHauraESharmaABeplerGDNA synthesis and repair genes RRM1 and ERCC1 in lung cancerN Engl J Med2007356880080817314339
  • NalbandianAYanBSPichuginABronsonRTKramnikILung carcinogenesis induced by chronic tuberculosis infection: the experimental model and genetic controlOncogene200928171928193819330024
  • AbrahamNSByrneCJYoungJMSolomonMJMeta-analysis of well-designed nonrandomized comparative studies of surgical procedures is as good as randomized controlled trialsJ Clin Epidemiol201063323824519716267