RSF-1 siRNA Enhances Tumor Radiosensitivity in Cervical Cancer via Enhanced DNA Damage, Cell Cycle Redistribution, and Promotion of Apoptosis

References

• Wright JD, Chen L, Tergas AI, et al. Population-level trends in relative survival for cervical cancer. Am J Obstet Gynecol. 2015;213(5):670 e671–677. doi:10.1016/j.ajog.2015.07.01226210758
   PubMed Web of Science ®Google Scholar
• Loyola A, Huang JY, LeRoy G, et al. Functional analysis of the subunits of the chromatin assembly factor RSF. Mol Cell Biol. 2003;23(19):6759–6768. doi:10.1128/MCB.23.19.6759-6768.200312972596
   PubMed Web of Science ®Google Scholar
• Perpelescu M, Nozaki N, Obuse C, Yang H, Yoda K. Active establishment of centromeric CENP-A chromatin by RSF complex. J Cell Biol. 2009;185(3):397–407. doi:10.1083/jcb.20090308819398759
   PubMed Web of Science ®Google Scholar
• Shih IM, Sheu JJ, Santillan A, et al. Amplification of a chromatin remodeling gene, Rsf-1/HBXAP, in ovarian carcinoma. Proc Natl Acad Sci U S A. 2005;102(39):14004–14009. doi:10.1073/pnas.050419510216172393
   PubMed Web of Science ®Google Scholar
• Li H, Zhang Y, Zhang Y, Bai X, Peng Y, He P. Rsf-1 overexpression in human prostate cancer, implication as a prognostic marker. Tumour Biol. 2014;35(6):5771–5776. doi:10.1007/s13277-014-1766-724584698
   PubMedGoogle Scholar
• Hu B-S, Yu H-F, Zhao G, Zha T-Z. High RSF-1 expression correlates with poor prognosis in patients with gastric adenocarcinoma. Int J Clin Exp Pathol. 2012;5(7):668–673.22977663
   PubMed Web of Science ®Google Scholar
• Xie C, Fu L, Xie L, Liu N, Li Q. Rsf-1 overexpression serves as a prognostic marker in human hepatocellular carcinoma. Tumour Biol. 2014;35(8):7595–7601. doi:10.1007/s13277-014-2008-824798976
   PubMedGoogle Scholar
• Liu S, Dong Q, Wang E. Rsf-1 overexpression correlates with poor prognosis and cell proliferation in colon cancer. Tumour Biol. 2012;33(5):1485–1491. doi:10.1007/s13277-012-0399-y22528946
   PubMedGoogle Scholar
• Li Q, Dong Q, Wang E. Rsf-1 is overexpressed in non-small cell lung cancers and regulates cyclinD1 expression and ERK activity. Biochem Biophys Res Commun. 2012;420(1):6–10. doi:10.1016/j.bbrc.2012.02.09522387541
   PubMed Web of Science ®Google Scholar
• Liu Y, Gai J, Fu L, Zhang X, Wang E, Li Q. Effects of RSF-1 on proliferation and apoptosis of breast cancer cells. Oncol Lett. 2018;16(4):4279–4284. doi:10.3892/ol.2018.917230214561
   PubMed Web of Science ®Google Scholar
• Fang FM, Li CF, Huang HY, et al. Overexpression of a chromatin remodeling factor, RSF-1/HBXAP, correlates with aggressive oral squamous cell carcinoma. Am J Pathol. 2011;178(5):2407–2415. doi:10.1016/j.ajpath.2011.01.04321514451
   PubMed Web of Science ®Google Scholar
• Chen X, Sun X, Guan J, et al. Rsf-1 influences the sensitivity of non-small cell lung cancer to paclitaxel by regulating NF-kappaB pathway and its downstream proteins. Cell Physiol Biochem. 2017;44(6):2322–2336. doi:10.1159/00048611629258089
   PubMedGoogle Scholar
• Liu F, Tai Y, Ma J. LncRNA NEAT1/let-7a-5p axis regulates the cisplatin resistance in nasopharyngeal carcinoma by targeting Rsf-1 and modulating the Ras-MAPK pathway. Cancer Biol Ther. 2018;19(6):534–542. doi:10.1080/15384047.2018.145011929565706
   PubMed Web of Science ®Google Scholar
• Wang X, Sheu JJ, Lai MT, et al. RSF-1 overexpression determines cancer progression and drug resistance in cervical cancer. Biomedicine (Taipei). 2018;8(1):4. doi:10.1051/bmdcn/201808010429480799
   PubMedGoogle Scholar
• Sheu JJ, Choi JH, Yildiz I, et al. The roles of human sucrose nonfermenting protein 2 homologue in the tumor-promoting functions of Rsf-1. Cancer Res. 2008;68(11):4050–4057. doi:10.1158/0008-5472.CAN-07-324018519663
   PubMed Web of Science ®Google Scholar
• Sanchez-Garcia F, Villagrasa P, Matsui J, et al. Integration of genomic data enables selective discovery of breast cancer drivers. Cell. 2014;159(6):1461–1475. doi:10.1016/j.cell.2014.10.04825433701
   PubMed Web of Science ®Google Scholar
• Zhang X, Fu L, Xue D, et al. Overexpression of Rsf-1 correlates with poor survival and promotes invasion in non-small cell lung cancer. Virchows Arch. 2017;470(5):553–560. doi:10.1007/s00428-017-2102-628289901
   PubMed Web of Science ®Google Scholar
• Wu J, Hu L, Wu F, He T. Prognostic value of rsf-1/hbxap in human solid tumors: a meta-analysis of cohort studies. Int J Clin Exp Med. 2015;8(2):1944–1955.25932123
   PubMed Web of Science ®Google Scholar
• Tai HC, Huang HY, Lee SW, et al. Associations of Rsf-1 overexpression with poor therapeutic response and worse survival in patients with nasopharyngeal carcinoma. J Clin Pathol. 2012;65(3):248–253. doi:10.1136/jclinpath-2011-20041322081787
   PubMed Web of Science ®Google Scholar
• Lin CY, Tian YF, Wu LC, et al. Rsf-1 expression in rectal cancer: with special emphasis on the independent prognostic value after neoadjuvant chemoradiation. J Clin Pathol. 2012;65(8):687–692. doi:10.1136/jclinpath-2012-20078622569540
   PubMed Web of Science ®Google Scholar
• Liang PI, Wu LC, Sheu JJ, et al. Rsf-1/HBXAP overexpression is independent of gene amplification and is associated with poor outcome in patients with urinary bladder urothelial carcinoma. J Clin Pathol. 2012;65(9):802–807. doi:10.1136/jclinpath-2012-20089722685262
   PubMed Web of Science ®Google Scholar
• Eriksson D, Stigbrand T. Radiation-induced cell death mechanisms. Tumour Biol. 2010;31(4):363–372. doi:10.1007/s13277-010-0042-820490962
   PubMedGoogle Scholar
• Zhao XC, An P, Wu XY, et al. Overexpression of hSNF2H in glioma promotes cell proliferation, invasion, and chemoresistance through its interaction with Rsf-1. Tumour Biol. 2016;37(6):7203–7212. doi:10.1007/s13277-015-4579-426666816
   PubMedGoogle Scholar
• Choi JH, Sheu JJ, Guan B, et al. Functional analysis of 11q13.5 amplicon identifies Rsf-1 (HBXAP) as a gene involved in paclitaxel resistance in ovarian cancer. Cancer Res. 2009;69(4):1407–1415. doi:10.1158/0008-5472.CAN-08-360219190325
   PubMed Web of Science ®Google Scholar
• Liu Y, Li G, Liu C, Tang Y, Zhang S. RSF1 regulates the proliferation and paclitaxel resistance via modulating NF-kappaB signaling pathway in nasopharyngeal carcinoma. J Cancer. 2017;8(3):354–362. doi:10.7150/jca.1672028261335
   PubMed Web of Science ®Google Scholar
• Al-Ejeh F, Kumar R, Wiegmans A, Lakhani SR, Brown MP, Khanna KK. Harnessing the complexity of DNA-damage response pathways to improve cancer treatment outcomes. Oncogene. 2010;29(46):6085–6098. doi:10.1038/onc.2010.40720818418
   PubMed Web of Science ®Google Scholar
• Kshirsagar M, Jiang W, Shih IM. DNA damage response is prominent in ovarian high-grade serous carcinomas, especially those with Rsf-1 (HBXAP) overexpression. J Oncol. 2012;2012:621685. doi:10.1155/2012/62168522028712
   PubMedGoogle Scholar
• Sheu JJ, Guan B, Choi JH, et al. Rsf-1, a chromatin remodeling protein, induces DNA damage and promotes genomic instability. J Biol Chem. 2010;285(49):38260–38269. doi:10.1074/jbc.M110.13873520923775
   PubMed Web of Science ®Google Scholar
• Sheu JJ, Choi JH, Guan B, et al. Rsf-1, a chromatin remodelling protein, interacts with cyclin E1 and promotes tumour development. J Pathol. 2013;229(4):559–568. doi:10.1002/path.414723378270
   PubMed Web of Science ®Google Scholar
• Min S, Jo S, Lee HS, et al. ATM-dependent chromatin remodeler Rsf-1 facilitates DNA damage checkpoints and homologous recombination repair. Cell Cycle. 2014;13(4):666–677. doi:10.4161/cc.2754824351651
   PubMed Web of Science ®Google Scholar