Downregulation of Hsa_circ_0000735 Inhibits the Proliferation, Migration, Invasion, and Glycolysis in Non-small-cell Lung Cancer by Targeting miR-940/BMPER Axis

References

• Bray F, Ferlay J, Soerjomataram I, et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68(6):394–424. doi:10.3322/caac.2149230207593
   PubMed Web of Science ®Google Scholar
• Wu YL, Planchard D, Lu S, et al. Pan-Asian adapted Clinical Practice Guidelines for the management of patients with metastatic non-small-cell lung cancer: a CSCO-ESMO initiative endorsed by JSMO, KSMO, MOS, SSO and TOS. Ann Oncol. 2019;30(2):171–210. doi:10.1093/annonc/mdy55430596843
   PubMed Web of Science ®Google Scholar
• Gupta GP, Massagué J. Cancer metastasis: building a framework. Cell. 2006;127(4):679–695. doi:10.1016/j.cell.2006.11.00117110329
   PubMed Web of Science ®Google Scholar
• Uramoto H, Tanaka F. Recurrence after surgery in patients with NSCLC. Transl Lung Cancer Res. 2014;3(4):242–249.25806307
   PubMedGoogle Scholar
• Wilusz JE, Sharp PA. Molecular biology. A circuitous route to noncoding RNA. Science. 2013;340(6131):440–441. doi:10.1126/science.123852223620042
   PubMed Web of Science ®Google Scholar
• Zhou R, Wu Y, Wang W, et al. Circular RNAs (circRNAs) in cancer. Cancer Lett. 2018;425:134–142. doi:10.1016/j.canlet.2018.03.03529625140
   PubMed Web of Science ®Google Scholar
• Li J, Yang J, Zhou P, et al. Circular RNAs in cancer: novel insights into origins, properties, functions and implications. Am J Cancer Res. 2015;5(2):472–480.25973291
   PubMed Web of Science ®Google Scholar
• Lasda E, Parker R. Circular RNAs: diversity of form and function. RNA. 2014;20(12):1829–1842. doi:10.1261/rna.047126.11425404635
   PubMed Web of Science ®Google Scholar
• Zhao X, Cai Y, Xu J. Circular RNAs: biogenesis, mechanism, and function in human cancers. Int J Mol Sci. 2019;20(16):3926. doi:10.3390/ijms20163926
   PubMed Web of Science ®Google Scholar
• Li C, Zhang L, Meng G, et al. Circular RNAs: pivotal molecular regulators and novel diagnostic and prognostic biomarkers in non-small cell lung cancer. J Cancer Res Clin Oncol. 2019;145(12):2875–2889. doi:10.1007/s00432-019-03045-431630262
   PubMed Web of Science ®Google Scholar
• Li W, Jiang W, Liu T, et al. Enhanced expression of circ_0000735 forecasts clinical severity in NSCLC and promotes cell progression via sponging miR-1179 and miR-1182. Biochem Biophys Res Commun. 2019;510(3):467–471. doi:10.1016/j.bbrc.2019.01.13430737027
   PubMed Web of Science ®Google Scholar
• Bartel DP. MicroRNAs: target recognition and regulatory functions. Cell. 2009;136(2):215–233. doi:10.1016/j.cell.2009.01.00219167326
   PubMed Web of Science ®Google Scholar
• Li Q, Wu X, Guo L, et al. MicroRNA-7-5p induces cell growth inhibition, cell cycle arrest and apoptosis by targeting PAK2 in non-small cell lung cancer. FEBS Open Biol. 2019;9(11):1983–1993. doi:10.1002/2211-5463.12738
   PubMed Web of Science ®Google Scholar
• Wang Z, Han Z, Zhang L, et al. MicroRNA-98-5p regulates the proliferation and apoptosis of A549 cells by targeting MAP4K3. Oncol Lett. 2019;18(4):4288–4293.31579095
   PubMed Web of Science ®Google Scholar
• Liu W, Xu Y, Guan H, et al. Clinical potential of miR-940 as a diagnostic and prognostic biomarker in breast cancer patients. Cancer Biomark. 2018;22(3):487–493. doi:10.3233/CBM-17112429843213
   PubMed Web of Science ®Google Scholar
• Hu J, Li C, Liu C, et al. Expressions of miRNAs in papillary thyroid carcinoma and their associations with the clinical characteristics of PTC. Cancer Biomark. 2017;18(1):87–94. doi:10.3233/CBM-16172328085013
   PubMed Web of Science ®Google Scholar
• Gu GM, Zhan YY, Abuduwaili K, et al. MiR-940 inhibits the progression of NSCLC by targeting FAM83F. Eur Rev Med Pharmacol Sci. 2018;22(18):5964–5971.30280778
   PubMed Web of Science ®Google Scholar
• Jiang K, Zhao T, Shen M, et al. MiR-940 inhibits TGF-beta-induced epithelial-mesenchymal transition and cell invasion by targeting Snail in non-small cell lung cancer. J Cancer. 2019;10(12):2735–2744. doi:10.7150/jca.3180031258781
   PubMed Web of Science ®Google Scholar
• Moser M, Binder O, Wu Y, et al. BMPER, a novel endothelial cell precursor-derived protein, antagonizes bone morphogenetic protein signaling and endothelial cell differentiation. Mol Cell Biol. 2003;23(16):5664–5679. doi:10.1128/MCB.23.16.5664-5679.200312897139
   PubMed Web of Science ®Google Scholar
• Heinke J, Wehofsits L, Zhou Q, et al. BMPER is an endothelial cell regulator and controls bone morphogenetic protein-4-dependent angiogenesis. Circ Res. 2008;103(8):804–812. doi:10.1161/CIRCRESAHA.108.17843418787191
   PubMed Web of Science ®Google Scholar
• Dituri F, Cossu C, Mancarella S, et al. The interactivity between TGFbeta and BMP signaling in organogenesis, fibrosis, and cancer. Cells. 2019;8(10):1130. doi:10.3390/cells8101130
   PubMed Web of Science ®Google Scholar
• Xu Y, Wang J, Qiu M, et al. Upregulation of the long noncoding RNA TUG1 promotes proliferation and migration of esophageal squamous cell carcinoma. Tumour Biol. 2015;36(3):1643–1651. doi:10.1007/s13277-014-2763-625366138
   PubMedGoogle Scholar
• Xue M, Shi D, Xu G, Wang W. The long noncoding RNA linc00858 promotes progress of lung cancer through miR-3182/MMP2 axis. Artif Cells Nanomed Biotechnol. 2019;47(1):2091–2097. doi:10.1080/21691401.2019.161772831131637
   PubMed Web of Science ®Google Scholar
• Wang X, Qi G, Zhang J, et al. Knockdown of long noncoding RNA small nucleolar RNA host gene 12 inhibits cell growth and induces apoptosis by upregulating miR-138 in nonsmall cell lung cancer. DNA Cell Biol. 2017;36(11):892–900. doi:10.1089/dna.2017.383028872894
   PubMed Web of Science ®Google Scholar
• Zhao SJ, Shen YF, Li Q, et al. SLIT2/ROBO1 axis contributes to the Warburg effect in osteosarcoma through activation of SRC/ERK/c-MYC/PFKFB2 pathway. Cell Death Dis. 2018;9(3):390. doi:10.1038/s41419-018-0419-y29523788
   PubMedGoogle Scholar
• Zhang S, Zeng X, Ding T, et al. Microarray profile of circular RNAs identifies hsa_circ_0014130 as a new circular RNA biomarker in non-small cell lung cancer. Sci Rep. 2018;8(1):2878. doi:10.1038/s41598-018-21300-529440731
   PubMed Web of Science ®Google Scholar
• Li P, Xiao Z, Luo J, et al. MiR-139-5p, miR-940 and miR-193a-5p inhibit the growth of hepatocellular carcinoma by targeting SPOCK1. J Cell Mol Med. 2019;23(4):2475–2488. doi:10.1111/jcmm.1412130710422
   PubMed Web of Science ®Google Scholar
• Luo H, Xu R, Chen B, et al. MicroRNA-940 inhibits glioma cells proliferation and cell cycle progression by targeting CKS1. Am J Transl Res. 2019;11(8):4851–4865.31497204
   PubMed Web of Science ®Google Scholar
• Zhou Z, Xu YP, Wang LJ, et al. miR-940 potentially promotes proliferation and metastasis of endometrial carcinoma through regulation of MRVI1. Biosci Rep. 2019;39(6):2. doi:10.1042/BSR20190077
   Google Scholar
• Moser M, Patterson C. Bone morphogenetic proteins and vascular differentiation: bMPing up vasculogenesis. Thromb Haemost. 2005;94(4):713–718.16270622
   PubMed Web of Science ®Google Scholar
• Schmierer B, Hill CS. TGFbeta-SMAD signal transduction: molecular specificity and functional flexibility. Nat Rev Mol Cell Biol. 2007;8(12):970–982. doi:10.1038/nrm229718000526
   PubMed Web of Science ®Google Scholar
• Dyer L, Lockyer P, Wu Y, et al. BMPER promotes epithelial-mesenchymal transition in the developing cardiac cushions. PLoS One. 2015;10(9):e0139209. doi:10.1371/journal.pone.013920926418455
   PubMed Web of Science ®Google Scholar
• Lockhart-Cairns MP, Lim KTW, Zuk A, et al. Internal cleavage and synergy with twisted gastrulation enhance BMP inhibition by BMPER. Matrix Biol. 2019;77:73–86. doi:10.1016/j.matbio.2018.08.00630125619
   PubMed Web of Science ®Google Scholar
• Patel N, Masaratana P, Diaz-Castro J, et al. BMPER protein is a negative regulator of hepcidin and is up-regulated in hypotransferrinemic mice. J Biol Chem. 2012;287(6):4099–4106. doi:10.1074/jbc.M111.31078922144676
   PubMed Web of Science ®Google Scholar
• Heinke J, Kerber M, Rahner S, et al. Bone morphogenetic protein modulator BMPER is highly expressed in malignant tumors and controls invasive cell behavior. Oncogene. 2012;31(24):2919–2930. doi:10.1038/onc.2011.47322020334
   PubMed Web of Science ®Google Scholar
• Lin KY, Lu D, Hung CF, et al. Ectopic expression of vascular cell adhesion molecule-1 as a new mechanism for tumor immune evasion. Cancer Res. 2007;67(4):1832–1841. doi:10.1158/0008-5472.CAN-06-301417308126
   PubMed Web of Science ®Google Scholar
• Lockyer P, Mao H, Fan Q, et al. LRP1-dependent BMPER signaling regulates lipopolysaccharide-induced vascular inflammation. Arterioscler Thromb Vasc Biol. 2017;37(8):1524–1535. doi:10.1161/ATVBAHA.117.30952128596374
   PubMed Web of Science ®Google Scholar