Identification of microRNA Signature and Key Genes Between Adenoma and Adenocarcinomas Using Bioinformatics Analysis

References

• Steele SR, Chang GJ, Hendren S, et al. Practice guideline for the surveillance of patients after curative treatment of colon and rectal cancer. Dis Colon Rectum. 2015;58(8):713–725. doi:10.1097/DCR.0000000000000410
   PubMed Web of Science ®Google Scholar
• Vogel JD, Eskicioglu C, Weiser MR, Feingold DL, Steele SR. The American society of colon and rectal surgeons clinical practice guidelines for the treatment of colon cancer. Dis Colon Rectum. 2017;60(10):999–1017. doi:10.1097/DCR.0000000000000926
   PubMed Web of Science ®Google Scholar
• Balch C, Ramapuram JB, Tiwari AK. The Epigenomics of embryonic pathway signaling in colorectal cancer. Front Pharmacol. 2017;8:267. doi:10.3389/fphar.2017.00267
   PubMed Web of Science ®Google Scholar
• Zarkavelis G, Boussios S, Papadaki A, Katsanos KH, Christodoulou DK, Pentheroudakis G. Current and future biomarkers in colorectal cancer. Ann Gastroenterol. 2017;30(6):613–621.
   PubMed Web of Science ®Google Scholar
• Ma Y, Pan X, Xu P, et al. Plasma microRNA alterations between EGFR-activating mutational NSCLC patients with and without primary resistance to TKI. Oncotarget. 2017;8(51):88529–88536. doi:10.18632/oncotarget.19874
   PubMedGoogle Scholar
• Ren P, Gong F, Zhang Y, Jiang J, Zhang H. MicroRNA-92a promotes growth, metastasis, and chemoresistance in non-small cell lung cancer cells by targeting PTEN. Tumour Biol. 2016;37(3):3215–3225. doi:10.1007/s13277-015-4150-3
   PubMedGoogle Scholar
• Sin TK, Wang F, Meng F, et al. Implications of MicroRNAs in the treatment of gefitinib-resistant non-small cell lung cancer. Int J Mol Sci. 2016;17(2):237. doi:10.3390/ijms17020237
   PubMed Web of Science ®Google Scholar
• Ma X, Liang AL, Liu YJ. Research progress on the relationship between lung cancer drug-resistance and microRNAs. J Cancer. 2019;10(27):6865–6875. doi:10.7150/jca.31952
   PubMed Web of Science ®Google Scholar
• Kania EE, Carvajal-Moreno J, Hernandez VA, et al. hsa-miR-9-3p and hsa-miR-9-5p as Post-Transcriptional Modulators of DNA Topoisomerase IIalpha in Human Leukemia K562 Cells with Acquired Resistance to Etoposide. Mol Pharmacol. 2020;97(3):159–170.
   PubMed Web of Science ®Google Scholar
• Boussios S, Ozturk MA, Moschetta M, et al. The developing story of predictive biomarkers in colorectal cancer. J Pers Med. 2019;9(1):12. doi:10.3390/jpm9010012
   PubMed Web of Science ®Google Scholar
• Li L, Wang G, Li N, Yu H, Si J, Wang J. Identification of key genes and pathways associated with obesity in children. Exp Ther Med. 2017;14(2):1065–1073. doi:10.3892/etm.2017.4597
   PubMed Web of Science ®Google Scholar
• Ikeda N, Nakajima Y, Tokuhara T, et al. Clinical significance of aminopeptidase N/CD13 expression in human pancreatic carcinoma. Clin Cancer Res. 2003;9(4):1503–1508.
   PubMed Web of Science ®Google Scholar
• Veenman CJ, Tax DM. LESS: a model-based classifier for sparse subspaces. IEEE Trans Pattern Anal Mach Intell. 2005;27(9):1496–1500. doi:10.1109/TPAMI.2005.182
   PubMed Web of Science ®Google Scholar
• Pollock BE, Storlie CB, Link MJ, Stafford SL, Garces YI, Foote RL. Comparative analysis of arteriovenous malformation grading scales in predicting outcomes after stereotactic radiosurgery. J Neurosurg. 2017;126(3):852–858. doi:10.3171/2015.11.JNS151300
   PubMed Web of Science ®Google Scholar
• Kitahara O, Furukawa Y, Tanaka T, et al. Alterations of gene expression during colorectal carcinogenesis revealed by cDNA microarrays after laser-capture microdissection of tumor tissues and normal epithelia. Cancer Res. 2001;61(9):3544–3549.
   PubMed Web of Science ®Google Scholar
• Lechner S, Muller-Ladner U, Renke B, Scholmerich J, Ruschoff J, Kullmann F. Gene expression pattern of laser microdissected colonic crypts of adenomas with low grade dysplasia. Gut. 2003;52(8):1148–1153. doi:10.1136/gut.52.8.1148
   PubMed Web of Science ®Google Scholar
• Notterman DA, Alon U, Sierk AJ, Levine AJ. Transcriptional gene expression profiles of colorectal adenoma, adenocarcinoma, and normal tissue examined by oligonucleotide arrays. Cancer Res. 2001;61(7):3124–3130.
   PubMed Web of Science ®Google Scholar
• Perez R, Wu N, Klipfel AA, Beart RW. A better cell cycle target for gene therapy of colorectal cancer: cyclin G. J Gastrointest Surg. 2003;7(7):884–889. doi:10.1007/s11605-003-0034-8
   PubMed Web of Science ®Google Scholar
• Tominaga O, Nita ME, Nagawa H, Fujii S, Tsuruo T, Muto T. Expressions of cell cycle regulators in human colorectal cancer cell lines. Jpn J Cancer Res. 1997;88(9):855–860. doi:10.1111/j.1349-7006.1997.tb00461.x
   PubMedGoogle Scholar
• Djamgoz MB, Coombes RC, Schwab A. Ion transport and cancer: from initiation to metastasis. Philos Trans R Soc Lond B Biol Sci. 2014;369(1638):20130092. doi:10.1098/rstb.2013.0092
   PubMed Web of Science ®Google Scholar
• Hakomori S. Tumor-associated carbohydrate antigens defining tumor malignancy: basis for development of anti-cancer vaccines. Adv Exp Med Biol. 2001;491:369–402.
   PubMed Web of Science ®Google Scholar
• Yue T, Goldstein IJ, Hollingsworth MA, Kaul K, Brand RE, Haab BB. The prevalence and nature of glycan alterations on specific proteins in pancreatic cancer patients revealed using antibody-lectin sandwich arrays. Mol Cell Proteomics. 2009;8(7):1697–1707. doi:10.1074/mcp.M900135-MCP200
   PubMed Web of Science ®Google Scholar
• Wang Z, Zhang J, Chen L, Li J, Zhang H, Guo X. Glycine Suppresses AGE/RAGE Signaling pathway and subsequent oxidative stress by restoring Glo1 function in the aorta of diabetic rats and in HUVECs. Oxid Med Cell Longev. 2019;2019:4628962.
   PubMed Web of Science ®Google Scholar
• Premkumar LS, Abooj M. TRP channels and analgesia. Life Sci. 2013;92(8–9):415–424. doi:10.1016/j.lfs.2012.08.010
   PubMed Web of Science ®Google Scholar
• Ahmadi A, Khansarinejad B, Hosseinkhani S, Ghanei M, Mowla SJ. miR-199a-5p and miR-495 target GRP78 within UPR pathway of lung cancer. Gene. 2017;620:15–22. doi:10.1016/j.gene.2017.03.032
   PubMed Web of Science ®Google Scholar
• Wang Y, Lin Y. Hsa-mir-127 impairs survival of patients with glioma and promotes proliferation, migration and invasion of cancerous cells by modulating replication initiator 1. Neuroreport. 2018;29(14):1166–1173. doi:10.1097/WNR.0000000000001089
   PubMed Web of Science ®Google Scholar
• Onnis A, Navari M, Antonicelli G, et al. Epstein-Barr nuclear antigen 1 induces expression of the cellular microRNA hsa-miR-127 and impairing B-cell differentiation in EBV-infected memory B cells. New insights into the pathogenesis of Burkitt lymphoma. Blood Cancer J. 2012;2:e84. doi:10.1038/bcj.2012.29
   PubMed Web of Science ®Google Scholar
• Jin S, Liu MD, Wu H, et al. Overexpression of hsa-miR-125a-5p enhances proliferation, migration and invasion of head and neck squamous cell carcinoma cell lines by upregulating C-C chemokine receptor type 7. Oncol Lett. 2018;15(6):9703–9710.
   PubMed Web of Science ®Google Scholar
• Jiang L, Chang J, Zhang Q, Sun L, Qiu X. MicroRNA hsa-miR-125a-3p activates p53 and induces apoptosis in lung cancer cells. Cancer Invest. 2013;31(8):538–544. doi:10.3109/07357907.2013.820314
   PubMed Web of Science ®Google Scholar
• Xu X, Lv YG, Yan CY, Yi J, Ling R. Enforced expression of hsa-miR-125a-3p in breast cancer cells potentiates docetaxel sensitivity via modulation of BRCA1 signaling. Biochem Biophys Res Commun. 2016;479(4):893–900. doi:10.1016/j.bbrc.2016.09.087
   PubMed Web of Science ®Google Scholar
• Choi ES, Lee H, Lee CH, Goh SH. Overexpression of KLHL23 protein from read-through transcription of PHOSPHO2-KLHL23 in gastric cancer increases cell proliferation. FEBS Open Bio. 2016;6(11):1155–1164. doi:10.1002/2211-5463.12136
   PubMed Web of Science ®Google Scholar
• Huber FM, Greenblatt SM, Davenport AM, et al. Histone-binding of DPF2 mediates its repressive role in myeloid differentiation. Proc Natl Acad Sci U S A. 2017;114(23):6016–6021. doi:10.1073/pnas.1700328114
   PubMed Web of Science ®Google Scholar
• Abba M, Patil N, Rasheed K, et al. Unraveling the role of FOXQ1 in colorectal cancer metastasis. Mol Cancer Res. 2013;11(9):1017–1028. doi:10.1158/1541-7786.MCR-13-0024
   PubMed Web of Science ®Google Scholar
• Peng X, Luo Z, Kang Q, et al. FOXQ1 mediates the crosstalk between TGF-beta and Wnt signaling pathways in the progression of colorectal cancer. Cancer Biol Ther. 2015;16(7):1099–1109. doi:10.1080/15384047.2015.1047568
   PubMed Web of Science ®Google Scholar
• Scorilas A, Kyriakopoulou L, Yousef GM, Ashworth LK, Kwamie A, Diamandis EP. Molecular cloning, physical mapping, and expression analysis of a novel gene, BCL2L12, encoding a proline-rich protein with a highly conserved BH2 domain of the Bcl-2 family. Genomics. 2001;72(2):217–221. doi:10.1006/geno.2000.6455
   PubMed Web of Science ®Google Scholar
• Scorilas A, Kyriakopoulou L, Yousef GM, Ashworth LK, Kwamie A, Diamandis EP. Molecular cloning, physical mapping, and expression analysis of a novel gene, BCL2L12, encoding a proline-rich protein with a highly conserved BH2 domain of the Bcl-2 family. Genomics. 2001;72(2):217–221.
   PubMed Web of Science ®Google Scholar
• Koch CA, Anderson D, Moran MF, Ellis C, Pawson T. SH2 and SH3 domains: elements that control interactions of cytoplasmic signaling proteins. Science. 1991;252(5006):668–674. doi:10.1126/science.1708916
   PubMed Web of Science ®Google Scholar
• Florou D, Papadopoulos IN, Scorilas A. Molecular analysis and prognostic impact of the novel apoptotic gene BCL2L12 in gastric cancer. Biochem Biophys Res Commun. 2010;391(1):214–218. doi:10.1016/j.bbrc.2009.11.034
   PubMed Web of Science ®Google Scholar
• Talieri M, Diamandis EP, Katsaros N, Gourgiotis D, Scorilas A. Expression of BCL2L12, a new member of apoptosis-related genes, in breast tumors. Thromb Haemost. 2003;89(6):1081–1088. doi:10.1055/s-0037-1613411
   PubMed Web of Science ®Google Scholar
• Boussios S, Mikropoulos C, Samartzis E, et al. Wise Management of Ovarian Cancer: on the Cutting Edge. J Pers Med. 2020;10(2):41. doi:10.3390/jpm10020041
   PubMed Web of Science ®Google Scholar
• Giotakis AI, Lazaris AC, Kataki A, Kontos CK, Giotakis EI. Positive BCL2L12 expression predicts favorable prognosis in patients with laryngeal squamous cell carcinoma. Cancer Biomark. 2019;25(2):141–149. doi:10.3233/CBM-181772
   PubMed Web of Science ®Google Scholar
• Kontos CK, Avgeris M, Vassilacopoulou D, Ardavanis A, Scorilas A. Molecular Effects of Treatment of Human Colorectal Cancer Cells with Natural and Classical Chemotherapeutic Drugs: alterations in the Expression of Apoptosis-related BCL2 Family Members, Including BCL2L12. Curr Pharm Biotechnol. 2018;19(13):1064–1075. doi:10.2174/1389201019666181112101410
   PubMed Web of Science ®Google Scholar
• Kivioja JL, Thanasopoulou A, Kumar A, et al. Dasatinib and navitoclax act synergistically to target NUP98-NSD1(+)/FLT3-ITD(+) acute myeloid leukemia. Leukemia. 2019;33(6):1360–1372. doi:10.1038/s41375-018-0327-2
   PubMed Web of Science ®Google Scholar