58
Views
6
CrossRef citations to date
0
Altmetric
Original Research

Clinical significance of the thymidylate synthase, dihydropyrimidine dehydrogenase, and thymidine phosphorylase mRNA expressions in hepatocellular carcinoma patients receiving 5-fluorouracil-based transarterial chemoembolization treatment

, , , , , , , , , & show all
Pages 811-818 | Published online: 03 Jul 2013

References

  • ParkinDMBrayFFerlayJPisaniPGlobal cancer statistics, 2002CA Cancer J Clin20055527410815761078
  • YehFSYuMCMoCCLuoSTongMJHendersonBEHepatitis B virus, aflatoxins, and hepatocellular carcinoma in southern Guangxi, ChinaCancer Res1989499250625092539905
  • KewMCYuMCKeddaMACoppinASarkinAHodkinsonJThe relative roles of hepatitis B and C viruses in the etiology of hepatocellular carcinoma in southern African blacksGastroenterology199711211841878978357
  • ParkinDMThe global health burden of infection-associated cancers in the year 2002Int J Cancer2006118123030304416404738
  • BruixJSalaMLlovetJMChemoembolization for hepatocellular carcinomaGastroenterology20041275 Suppl 1179S188S
  • De CarlisLGiacomoniAPirottaVSurgical treatment of hepatocellular cancer in the era of hepatic transplantationJ Am Coll Surg2003196688789712788425
  • LlovetJMRealMIMontanaXArterial embolisation or chemoembolisation versus symptomatic treatment in patients with unresectable hepatocellular carcinoma: a randomised controlled trialLancet 182002359931917341739
  • LlovetJMBruixJSystematic review of randomized trials for unresectable hepatocellular carcinoma: chemoembolization improves survivalHepatology200337242944212540794
  • PinedoHMPetersGFFluorouracil: biochemistry and pharmacologyJ Clin Oncol1988610165316643049954
  • PattYZYoffeBCharnsangavejCLow serum alpha-fetoprotein level in patients with hepatocellular carcinoma as a predictor of response to 5-FU and interferon-alpha-2bCancer1993729257425827691392
  • HwangJYJangBKKwonKMEfficacy of hepatic arterial infusion therapy for advanced hepatocellular carcinoma using 5-fluorouracil, epirubicin and mitomycin-CKorean J Gastroenterol2005452118124 Korean15725716
  • JangBKKwonKMChungWJEfficacy of hepatic arterial infusion therapy for advanced hepatocellular carcinoma using 5-fluorouracil and cisplatinKorean J Hepatol200410427127815613802
  • SalongaDDanenbergKDJohnsonMColorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase, and thymidine phosphorylaseClin Cancer Res2000641322132710778957
  • IchikawaWUetakeHShirotaYCombination of dihydropyrimidine dehydrogenase and thymidylate synthase gene expressions in primary tumors as predictive parameters for the efficacy of fluoropyrimidine-based chemotherapy for metastatic colorectal cancerClin Cancer Res20039278679112576451
  • BeckAEtienneMCCheradameSA role for dihydropyrimidine dehydrogenase and thymidylate synthase in tumour sensitivity to fluorouracilEur J Cancer199430A10151715227833111
  • TakahashiTYoshidaHMamadaYProfiling of fluorouracil-related genes by microdissection technique in hepatocellular carcinomaHepatogastroenterology200754781612161618019677
  • MatsudaMShibaSAsakawaMKonoHFujiiHComplete remission of multiple recurrent hepatocellular carcinomas by oral administration of enteric-coated tegafur/uracil in a patient with huge hepatocellular carcinoma extending to the inferior vena cava after hepatic resection: analysis of mRNA expression of fluoropyrimidine metabolism enzymes in the primary tumorInt J Clin Oncol200914324524819593617
  • BabaHTeramotoKKawamuraTMoriAImamuraMAriiSDihydropyrimidine dehydrogenase and thymidylate synthase activities in hepatocellular carcinomas and in diseased liversCancer Chemother Pharmacol200352646947613680162
  • EnomotoYItsuboMKawabeTTwo cases of transcatheter therapy to hepatocellular carcinoma supplied by the right internal mammary arteryNihon Shokakibyo Gakkai Zasshi2000975585589 Japanese10846414
  • SaccheriSLovariaASangiovanniASegmental transcatheter arterial chemoembolization treatment in patients with cirrhosis and inoperable hepatocellular carcinomasJ Vasc Interv Radiol2002131099599912397120
  • YuSCHuiJ WHuiE PEmbolization efficacy and treatment effectiveness of transarterial therapy for unresectable hepatocellular carcinoma: a case-controlled comparison of transarterial ethanol ablation with lipiodol-ethanol mixture versus transcatheter arterial chemoembolizationJ Vasc Interv Radiol200920335235919167240
  • MarelliLStiglianoRTriantosCTransarterial therapy for hepatocellular carcinoma: which technique is more effective? A systematic review of cohort and randomized studiesCardiovasc Intervent Radiol200730162517103105
  • MetzgerRDanenbergKLeichmanCGHigh basal level gene expression of thymidine phosphorylase (platelet-derived endothelial cell growth factor) in colorectal tumors is associated with nonresponse to 5-fluorouracilClin Cancer Res1998410237123769796967
  • FischelJLEtienneMCSpectorTFormentoPReneeNMilanoGDihydropyrimidine dehydrogenase: a tumoral target for fluorouracil modulationClin Cancer Res1995199919969816071
  • DiasioRBJohnsonMRDihydropyrimidine dehydrogenase: its role in 5-fluorouracil clinical toxicity and tumor resistanceClin Cancer Res19995102672267310537327
  • HoDHTownsendLLunaMABodeyG PDistribution and inhibition of dihydrouracil dehydrogenase activities in human tissues using 5-fluorouracil as a substrateAnticancer Res1986647817843752956
  • LuZZhangRDiasioRBDihydropyrimidine dehydrogenase activity in human peripheral blood mononuclear cells and liver: population characteristics, newly identified deficient patients, and clinical implication in 5-fluorouracil chemotherapyCancer Res19935322543354388221682
  • LuZZhangRDiasioRBPopulation characteristics of hepatic dihydropyrimidine dehydrogenase activity, a key metabolic enzyme in 5-fluorouracil chemotherapyClin Pharmacol Ther19955855125227586945
  • WeiXMcLeodHLMcMurroughJGonzalezFJFernandez-SalgueroPMolecular basis of the human dihydropyrimidine dehydrogenase deficiency and 5-fluorouracil toxicityJ Clin Invest19969836106158698850
  • HigashiyamaMKodamaKYokouchiHThymidylate synthase and dihydropyrimidine dehydrogenase activities in non-small cell lung cancer tissues: relationship with in vitro sensitivity to 5-fluorouracilLung Cancer200134340741611714538
  • YoshinareKKubotaTWatanabeMGene expression in colorectal cancer and in vitro chemosensitivity to 5-fluorouracil: a study of 88 surgical specimensCancer Sci200394763363812841874
  • IshikawaYKubotaTOtaniYDihydropyrimidine dehydrogenase and messenger RNA levels in gastric cancer: possible predictor for sensitivity to 5-fluorouracilJpn J Cancer Res200091110511210744051
  • KobayashiHKoikeTNakatsukaADihydropyrimidine dehydrogenase expression predicts survival outcome and chemosensitivity to 5-fluorouracil in patients with oral squamous cell carcinomaOral Oncol2005411384715598584
  • HoriguchiJYoshidaTKoibuchiYDPD activity and immunohistochemical DPD expression in human breast cancerOncol Rep2004111657214654904
  • HakamadaYTsuchidaAArimaMPrognostic predictors in breast cancer patients with postoperative 5-fluorouracil-based chemotherapyInt J Mol Med200516230931416012767
  • SoongRShahNSalto-TellezMPrognostic significance of thymidylate synthase, dihydropyrimidine dehydrogenase and thymidine phosphorylase protein expression in colorectal cancer patients treated with or without 5-fluorouracil-based chemotherapyAnn Oncol200819591591918245778
  • NiiAShimadaMIkegamiTSignificance of dihydropyrimidine dehydrogenase and thymidylate synthase mRNA expressions in hepatocellular carcinomaHepatol Res200939327428119054147
  • Van TriestBPinedoHMGiacconeGPetersGJDownstream molecular determinants of response to 5-fluorouracil and antifolate thymidylate synthase inhibitorsAnn Oncol200011438539110847455
  • KornmannMSchwabeWSanderSThymidylate synthase and dihydropyrimidine dehydrogenase mRNA expression levels: predictors for survival in colorectal cancer patients receiving adjuvant 5-fluorouracilClin Cancer Res20039114116412414519634
  • JohnstonPGBensonABIIICatalanoPRaoMSO’DwyerPJAllegraCJThymidylate synthase protein expression in primary colorectal cancer: lack of correlation with outcome and response to fluorouracil in metastatic disease sitesJ Clin Oncol200321581581912610179
  • NakagawaTOtakeYYanagiharaKExpression of thymidylate synthase is correlated with proliferative activity in non-small cell lung cancer (NSCLC)Lung Cancer200443214514914739034
  • LiMSLiPFChenQDuGGLiGAlpha-fetoprotein stimulated the expression of some oncogenes in human hepatocellular carcinoma Bel 7402 cellsWorld J Gastroenterol200410681982415040024
  • SoongRDiasioRBAdvances and challenges in fluoropyrimidine pharmacogenomics and pharmacogeneticsPharmacogenomics20056883584716296946
  • ThanasaiJLimpaiboonTJearanaikoonPEffects of thymidine phosphorylase on tumor aggressiveness and 5-fluorouracil sensitivity in cholangiocarcinomaWorld J Gastroenterol16131631163820355241