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Original Research

Novel covalent modification of human anaplastic lymphoma kinase (ALK) and potentiation of crizotinib-mediated inhibition of ALK activity by BNP7787

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Pages 375-383 | Published online: 04 Feb 2015

References

  • HausheerFBainSPerryMComprehensive meta-analysis of survival outcomes from two randomized multicenter trials in first-line advanced non-small cell lung cancer in patients treated with the novel investigational antitumor-enhancing and chemoprotective agent TavoceptEuropean J Clin Med Oncol201021719
  • American Cancer SocietyCancer Facts and Figures 2014American Cancer Society170Atlanta, GA
  • Cancer, Feb 2014, Fact Sheet No 297 [webpage on the Internet]GenevaWorld Health Organization Available from: http://www.who.int/mediacenter/factsheets/fs297/en/index.htmlAccessed November 13, 2014
  • RosellRRobinetGSzczesnaARandomized phase II study of cetuximab plus cisplatin/vinorelbine compared with cisplatin/vinorelbine alone as first-line therapy in EGFR-expressing advanced non-small-cell lung cancerAnn Oncol200819236236917947225
  • US Food and Drug AdministrationAvastin LabelUS Food and Drug Administration2004 Available from: http://www.accessdata.fda.gov/drugsatfda_docs/label/2011/125085s225lbl.pdfAccessed November 13, 2014
  • HausheerFHKochatHParkerARNew approaches to drug discovery and development: a mechanism-based approach to pharmaceutical research and its application to BNP7787, a novel chemoprotective agentCancer Chemother Pharmacol200352Suppl 1S3S1512819940
  • HausheerFHKanterPCaoSModulation of platinum-induced toxicities and therapeutic index: mechanistic insights and first- and second-generation protecting agentsSemin Oncol19982555845999783598
  • BovenEVerschraagenMHulscherTMBNP7787, a novel protector against platinum-related toxicities, does not affect the efficacy of cisplatin or carboplatin in human tumour xenograftsEur J Cancer20023881148115612008205
  • TakedaKNegoroSMatsuiKPhase I safety and pharmacokinetic trial of BNP7787 in patients receiving cisplatin (CDDP) and paclitaxel (PTX) for advanced non-small cell lung cancer (NSCLC): an Osaka phase 1 study group trialAmerican Society of Clinical Oncology2002 Abstract 453
  • PendyalaLSchwartzGSmithPZdanowiczJMurphyMHausheerFModulation of plasma thiols and mixed disulfides by BNP7787 in patients receiving paclitaxel/cisplatin therapyCancer Chemother Pharmacol200351537638412682786
  • PalmerRHVernerssonEGrabbeCHallbergBAnaplastic lymphoma kinase: signalling in development and diseaseBiochem J2009420334536119459784
  • HornLPaoWEML4-ALK: honing in on a new target in non-small-cell lung cancerJ Clin Oncol200927264232423519667260
  • ZhangXZhangSYangXFusion of EML4 and ALK is associated with development of lung adenocarcinomas lacking EGFR and KRAS mutations and is correlated with ALK expressionMol Cancer2010918820624322
  • GrandeEBolósMVArriolaETargeting oncogenic ALK: a promising strategy for cancer treatmentMol Cancer Ther20111056957921474455
  • ChiarleRVoenaCAmbrogioCPivaRInghiramiGThe anaplastic lymphoma kinase in the pathogenesis of cancerNat Rev Cancer200881112318097461
  • LeeCCJiaYLiNCrystal structure of the ALK (anaplastic lymphoma kinase) catalytic domainBiochem J2010430342543720632993
  • CuiJJTran-DubeMShenHStructure based drug design of crizotinib (PF-02341066), a potent and selective dual inhibitor of mesenchymal-epithelial transition factor (c-MET) kinase and anaplastic lymphoma kinase (ALK)J Med Chem2011546342636321812414
  • MIFit Open Source Project [homepage on the Internet]2010 Available from: http://code.google.com/p/mifit/. Accessed
  • MurshudovGNVaginAADodsonEJRefinement of macromolecular structures by the maximum-likelihood methodActa Crystallogr D Biol Crystallogr199753Pt 324025515299926
  • LuXErringtonJChenVJCurtinNJBoddyAVNewellDRCellular ATP depletion by LY309887 as a predictor of growth inhibition in human tumor cell linesClin Cancer Res20006127127710656458
  • University of LeedsNature’s batteries’ may have helped power early lifeforms [webpage on the Internet]RockvilleScienceDaily5252010 Available from: http://www.sciencedaily.com/releases/2010/05/100525094906.htmAccessed June 1, 2012
  • RappasMNiwaHZhangXMechanisms of ATPases - a multi-disciplinary approachCurr Protein Pept Sci2004528910515078220
  • VerschraagenMBovenEZegersIHausheerFHVan der VijghWJPharmacokinetics of BNP7787 and its metabolite mesna in plasma and ascites: a case reportCancer Chemother Pharmacol200351652552912750838
  • BangYJThe potential for crizotinib in non-small cell lung cancer: a perspective reviewTher Adv Med Oncol20113627929122084642
  • OuSHCrizotinib: a novel and first-in-class multitargeted tyrosine kinase inhibitor for the treatment of anaplastic lymphoma kinase rearranged non-small cell lung cancer and beyondDrug Des Devel Ther20115471485
  • ShackletonMQuintanaEFearonERMorrisonSJHeterogeneity in cancer: cancer stem cells versus clonal evolutionCell2009138582282919737509
  • HanahanDWeinbergRAHallmarks of cancer: the next generationCell2011144564667421376230
  • Dalle-DonneIRossiRColomboGGiustariniDMilzaniAProtein S-glutathionylation: a regulatory device from bacteria to humansTrends Biochem Sci2009342859619135374
  • MarinoSMGladyshevVNStructural analysis of cysteine S-nitrosylation: a modified acid-based motif and the emerging role of trans-nitrosylationJ Mol Biol2010395484485919854201
  • HouglandJLHicksKAHartmanHLKellyRAWattTJFierkeCAIdentification of novel peptide substrates for protein farnesyltransferase reveals two substrate classes with distinct sequence selectivitiesJ Mol Biol2010395117619019878682
  • DietrichLEUngermannCOn the mechanism of protein palmitoylationEMBO Rep20045111053105715520806
  • ParkerARPetluruPNWuMZhaoMKochatHHausheerFHBNP7787-mediated modulation of paclitaxel- and cisplatin-induced aberrant microtubule protein polymerization in vitroMol Cancer Ther2010992558256720807779