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Original Research

Evaluation of CYP2C19 Gene Polymorphisms in Patients with Acid Peptic Disorders Treated with Esomeprazole

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Pages 509-520 | Published online: 29 Apr 2021

References

  • Mejia A, Kraft WK. Acid peptic diseases: pharmacological approach to treatment. Expert Rev Clin Pharmacol. 2009;2(3):295–314. doi:10.1586/ecp.09.8
  • Cardona-Ospina JA, Medina-Morales DA, Rodr?guez-Morales AJ, Machado-Alba JE. Efectos adversos a largo plazo de los inhibidores de la bomba de protones. Perspectiva desde la medicina basada en la evidencia. Rev Colomb Gastroenterol. 2016;31:403–408. doi:10.22516/25007440.115
  • Donato MT 1. ¿Qué es el citocromo P-450 y cómo funciona? Maria Teresa Donato Martín. 2000:29–62.
  • Hunt SE, McLaren W, Gil L, et al. Ensembl variation resources. Database. 2018;2018.
  • Guengerich FP, Rendic S. Update information on drug metabolism systems— 2009, part I. Curr Drug Metab. 2010;11:1–3. doi:10.2174/138920010791110908
  • Zhang H-F, Wang -H-H, Gao N, et al. Physiological content and intrinsic activities of 10 cytochrome P450 isoforms in human normal liver microsomess. J Pharmacol Exp Ther. 2016;358(1):83–93. doi:10.1124/jpet.116.233635
  • Ph. D. Lemke TL, Ph. D. Williams DA, Ph. D. Roche VF, Ph. D. Zito SW, eds. Foye’s Principles of Medicinal Chemistry. Vol. 106. 2013. doi:10.1023/B:PRES.0000030927.38007.36
  • Hiratsuka M. Genetic polymorphisms and in vitro functional characterization of CYP2C8, CYP2C9, and CYP2C19 allelic variants. Biol Pharm Bull. 2016;39(11):1748–1759. doi:10.1248/bpb.b16-00605
  • Samer CF, Lorenzini KI, Rollason V, Daali Y, Desmeules JA. Applications of CYP450 testing in the clinical setting. Mol Diagn Ther. 2013;17(3):165–184. doi:10.1007/s40291-013-0028-5
  • Gaedigk A, Ingelman-Sundberg M, Miller NA, et al. The Pharmacogene Variation (PharmVar) consortium: incorporation of the human Cytochrome P450 (CYP) allele nomenclature database. Clin Pharmacol Ther. 2018;103(3):399–401. doi:10.1002/cpt.910
  • Zanger UM, Schwab M. Cytochrome P450 enzymes in drug metabolism: regulation of gene expression, enzyme activities, and impact of genetic variation. Pharmacol Ther. 2013;138:103–141.
  • Marjani A. Genetic variations in cytochrome P450 2C9 and 2C19: a review. Curr Pharmacogenomics Person Med. 2016;14:18–28. doi:10.2174/1875692115666161214152223
  • Lima JJ, Thomas CD, Barbarino J, et al. Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline for CYP2C19 and proton pump inhibitor dosing. Clin Pharmacol Ther. 2020. doi:10.1002/cpt.2015
  • Klotz U, Schwab M, Treiber G. CYP2C19 polymorphism and proton pump inhibitors. Basic Clin Pharmacol Toxicol. 2004;95(1):2–8. doi:10.1111/j.1600-0773.2004.pto950102.x
  • Guengerich FP. Cytochrome P450 and chemical toxicology. Chem Res Toxicol. 2008;21:70–83. doi:10.1021/tx700079z
  • Kamiya C, Inui N, Hakamata A, et al. Effect of co-administered inducer or inhibitor on omeprazole pharmacokinetics based on CYP2C19 genotype. J Pharmacol Sci. 2019;139:361–366. doi:10.1016/j.jphs.2019.03.001
  • Velazquez MNR, Parween S, Udhane SS, Pandey AV. Variability in human drug metabolizing cytochrome P450 CYP2C9, CYP2C19 and CYP3A5 activities caused by genetic variations in cytochrome P450 oxidoreductase. Biochem Biophys Res Commun. 2019;515(1):133–138. doi:10.1016/j.bbrc.2019.05.127
  • Tunthong R, Sukasem C, Puangpetch A, et al. Pharmacogenetic study of CYP2C19 variation and clopidogrel dose adjustment according to platelet reactivity monitoring in atherothromboticrisk patients in Thailand. Curr Pharmacogenomics Person Med. 2013;11:154–161. doi:10.2174/1875692111311020007
  • Cattaneo D, Perico N, Remuzzi G. From pharmacokinetics to pharmacogenomics: a new approach to tailor immunosuppressive therapy. Am J Transplant. 2004;4:299–310. doi:10.1111/j.1600-6143.2004.00312.x
  • Daly AK, Cascorbi I. Opportunities and limitations: the value of pharmacogenetics in clinical practice. Br J Clin Pharmacol. 2014;77:583–586. doi:10.1111/bcp.12354
  • Ur Rehman K, Akhtar T, Sabar MF, Tariq MA. Allele frequency distribution of CYP2C19*2 allelic variants associated with clopidogrel resistance in cardiac patients. Exp Ther Med. 2015;10:309–315. doi:10.1124/dmd.32.8.821
  • Zhong Z, Hou J, Li B, et al. Analysis of CYP2C19 genetic polymorphism in a large ethnic hakka population in southern China. Med Sci Monit. 2017;23:6186–6192. doi:10.12659/MSM.905337
  • Heredia MM, Araujo D, Rodríguez M, Sierra E. Genotypic and fenotypic characterization of CYP2C19 from a mestiza population in Colombia. Clin Chem Lab Med. 2015;53:S770.
  • Isaza C, Henao J, Isaza Martínez JH, Sepúlveda Arias JC, Beltrán L. Phenotype-genotype analysis of CYP2C19 in Colombian mestizo nidividuals. BMC Clin Pharmacol. 2007;7. doi:10.1186/1472-6904-7-6
  • Serrano D, Torrado S, Torrado-Santiago S, Gisbert JP. The influence of CYP2C19 genetic polymorphism on the pharmacokinetics/- pharmacodynamics of proton pump inhibitor-containing Helicobacter pylori treatments. Curr Drug Metab. 2012;13:1303–1312. doi:10.2174/138920012803341393
  • Bennadi D. Self-medication: a current challenge. J Basic Clin Pharm. 2013;5:19–23. doi:10.4103/0976-0105.128253
  • Scott SA, Martis S, Peter I, et al. Identification of CYP2C19*4B: pharmacogenetic implications for drug metabolism including clopidogrel responsiveness. Pharmacogenomics J. 2012;12(4):297–305. doi:10.1038/tpj.2011.5
  • Li XQ, Andersson TB, Ahlström M, Weidolf L. Comparison of inhibitory effects of the proton pump-inhibiting drugs omeprazole, esomeprazole, lansoprazole, pantoprazole, and rabeprazole on human cytochrome P450 activities. Drug Metab Dispos. 2004;32:821–827.
  • Aquilante CL, Niemi M, Gong L, Altman RB, Klein TE. PharmGKB summary: very important pharmacogene information for cytochrome P450, family 2, subfamily C, polypeptide 8. Pharmacogenet Genomics. 2013;23:721–728. doi:10.1097/FPC.0b013e3283653b27
  • De Morais SMF, Wilkinson GR, Blaisdell J, et al. The major genetic defect responsible for the polymorphism of S-mephenytoin metabolism in humans. J Biol Chem. 1994;269(22):15419–15422. doi:10.1016/S0021-9258(17)40694-6
  • Chaudhry AS, Prasad B, Shirasaka Y, et al. The CYP2C19 intron 2 branch point SNP is the ancestral polymorphism contributing to the poor metabolizer phenotype in livers with CYP2C19*35 and CYP2C19*2 alleles. Drug Metab Dispos. 2015;43(8):1226–1235. doi:10.1124/dmd.115.064428
  • Scott SA, Sangkuhl K, Gardner EE, et al. Clinical pharmacogenetics implementation consortium guidelines for cytochrome P450-2C19 (CYP2C19) genotype and clopidogrel therapy. Clin Pharmacol Ther. 2011;90:328–332. doi:10.1038/clpt.2011.132
  • Favela-Mendoza AF, Martinez-cortes G, Hernandez-zaragoza M, et al. Genetic variability of CYP2C19 in a Mexican population: contribution to the knowledge of the inheritance pattern of CYP2C19*17 to develop the ultrarapid metabolizer phenotype. J Genet. 2015;94(1):3–7. doi:10.1007/s12041-015-0477-1
  • Sugimoto K, Uno T, Yamazaki H, Tateishi T. Limited frequency of the CYP2C19*17 allele and its minor role in a Japanese population. Br J Clin Pharmacol. 2008;65:437–439. doi:10.1111/j.1365-2125.2007.03057.x
  • Martis S, Peter I, Hulot J-S, et al. Multi-ethnic distribution of clinically relevant CYP2C genotypes and haplotypes. Pharmacogenomics J. 2013;13(4):369–377. doi:10.1038/tpj.2012.10
  • CLM. IGSR population. Availbale from: https://www.internationalgenome.org/data-portal/population/CLM. Accessed April 8, 2021.
  • Ardlie KG, Kruglyak L, Seielstad M. Patterns of linkage disequilibrium in the human genome. Nat Rev Genet. 2002;3:299–309. doi:10.1038/nrg777
  • Bush WS, Moore JH, Lewitter F, Kann M. Chapter 11: genome-wide association studies. PLoS Comput Biol. 2012;8(12):e1002822. doi:10.1371/journal.pcbi.1002822
  • Dean L. Diazepam therapy and CYP2C19 genotype. In: Pratt VM, editor. Medical Genetics Summaries. US: National Center for Biotechnology Information; 2012.
  • Langaee TY, Zhu H-J, Wang X, et al. The influence of the CYP2C19*10 allele on clopidogrel activation and CYP2C19*2 genotyping. Pharmacogenet Genomics. 2014;24(8):381–386. doi:10.1097/FPC.0000000000000068
  • Zhang L, Sarangi V, Moon I, et al. CYP2C9 and CYP2C19: deep mutational scanning and functional characterization of genomic missense variants. Clin Transl Sci. 2020;13(4):727–742. doi:10.1111/cts.12758
  • El Rouby N, Lima JJ, Johnson JA. Proton pump inhibitors: from CYP2C19 pharmacogenetics to precision medicine. Expert Opin Drug Metab Toxicol. 2018;14(4):447–460. doi:10.1080/17425255.2018.1461835
  • Bhise NS, Elsayed AH, Cao X, Pounds S, Lamba JK. MicroRNAs mediated regulation of expression of nucleoside analog pathway genes in acute myeloid leukemia. Genes. 2019;10(4):319. doi:10.3390/genes10040319
  • Relling MV, Evans WE. Pharmacogenomics in the clinic. Nature. 2015;526(7573):343–350. doi:10.1038/nature15817
  • Rojas CA, Sepúlveda Copete M, García Abadía JA, et al. Un ensayo clínico piloto de la efectividad clínica de dos presentaciones de esomeprazol. Rev Colomb Gastroenterol. 2019;34(3):261–268. doi:10.22516/25007440.335
  • Dong Y, Xiao H, Wang Q, et al. Analysis of genetic variations in CYP2C9, CYP2C19, CYP2D6 and CYP3A5 genes using oligonucleotide microarray. Int J Clin Exp Med. 2015;8(10):18917–18926.
  • Ye C, Jin H, Zhang R, et al. Variability of warfarin dose response associated with CYP2C9 and VKORC1 gene polymorphisms in Chinese patients. J Int Med Res. 2014;42(1):67–76. doi:10.1177/0300060513499094
  • Al-Jenoobi FI, Alkharfy KM, Alghamdi AM, et al. CYP2C19 genetic polymorphism in Saudi Arabians. Basic Clin Pharmacol Toxicol. 2013;112(1):50–54. doi:10.1111/j.1742-7843.2012.00919.x