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Pharmacogenomics and Personalized Medicine Volume 14, 2021 - Issue
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Original Research

Genetic Association Study Revealed Three Loci Were Associated Risk of Myopia Among Minors

Zixiu ZhouNanjing Tongren Hospital, School of Medicine, Southeast University, Nanjing, 211102, People’s Republic of China
,
Sizhen LiNanjing Tongren Hospital, School of Medicine, Southeast University, Nanjing, 211102, People’s Republic of ChinaCorrespondence[email protected]
,
Qingsong YangNanjing Tongren Hospital, School of Medicine, Southeast University, Nanjing, 211102, People’s Republic of China
,
Xiaodong YangNanjing Tongren Hospital, School of Medicine, Southeast University, Nanjing, 211102, People’s Republic of China
,
Kuanxiao HaoNanjing Tongren Hospital, School of Medicine, Southeast University, Nanjing, 211102, People’s Republic of China
,
Yating LiuNanjing Tongren Hospital, School of Medicine, Southeast University, Nanjing, 211102, People’s Republic of China
&
Shanshan XuNanjing Tongren Hospital, School of Medicine, Southeast University, Nanjing, 211102, People’s Republic of China
 show all
Pages 547-551 | Published online: 11 May 2021

References

  • Foster PJ, Jiang Y. Epidemiology of myopia. Eye (Lond). 2014;28(2):202–208. doi:10.1038/eye.2013.280
  • Angle J, Wissmann DA. The epidemiology of myopia. Am J Epidemiol. 1980;111(2):220–228. doi:10.1093/oxfordjournals.aje.a112889
  • Grzybowski A, Kanclerz P, Tsubota K, Lanca C, Saw SM. A review on the epidemiology of myopia in school children worldwide. BMC Ophthalmol. 2020;20(1):27. doi:10.1186/s12886-019-1220-0
  • Wang J, Li Y, Zhao Z, et al. School-based epidemiology study of myopia in Tianjin, China. Int Ophthalmol. 2020;40(9):2213–2222. doi:10.1007/s10792-020-01400-w
  • Mak CY, Yam JC, Chen LJ, Lee SM, Young AL. Epidemiology of myopia and prevention of myopia progression in children in East Asia: a review. Hong Kong Med J. 2018;24(6):602–609.
  • Kunceviciene E, Liutkeviciene R, Budiene B, Sriubiene M, Smalinskiene A. Independent association of whole blood miR-328 expression and polymorphism at 3ʹUTR of the PAX6 gene with myopia. Gene. 2019;687:151–155. doi:10.1016/j.gene.2018.11.030
  • Zhang D, Zeng G, Hu J, McCormick K, Shi Y, Gong B. Association of IGF1 polymorphism rs6214 with high myopia: a systematic review and meta-analysis. Ophthalmic Genet. 2017;38(5):434–439. doi:10.1080/13816810.2016.1253105
  • Jin GM, Zhao XJ, Chen AM, Chen YX, Li Q. Association of COL1A1 polymorphism with high myopia: a Meta-analysis. Int J Ophthalmol. 2016;9(4):604–609.
  • Liang Y, Song Y, Zhang F, Sun M, Wang N. Effect of a single nucleotide polymorphism in the LAMA1 promoter region on Transcriptional activity: implication for pathological myopia. Curr Eye Res. 2016;41(10):1379–1386. doi:10.3109/02713683.2015.1118129
  • Chen T, Shan G, Ma J, Zhong Y. Polymorphism in the RASGRF1 gene with high myopia: a meta-analysis. Mol Vis. 2015;21:1272–1280.
  • Meguro A, Yamane T, Takeuchi M, et al. Genome-wide association study in asians identifies novel loci for high myopia and highlights a nervous system role in its pathogenesis. Ophthalmology. 2020;127(12):1612–1624. doi:10.1016/j.ophtha.2020.05.014
  • Luo HD, Gazzard G, Liang Y, Shankar A, Tan DT, Saw SM. Defining myopia using refractive error and uncorrected logMAR visual acuity >0.3 from 1334 Singapore school children ages 7–9 years. Br J Ophthalmol. 2006;90(3):362–366. doi:10.1136/bjo.2005.079657
  • Tideman JW, Polling JR, Voortman T, et al. Low serum vitamin D is associated with axial length and risk of myopia in young children. Eur J Epidemiol. 2016;31(5):491–499. doi:10.1007/s10654-016-0128-8
  • Recko M, Stahl ED. Childhood myopia: epidemiology, risk factors, and prevention. Mo Med. 2015;112(2):116–121.
  • Huang Y, Kee CS, Hocking PM, et al. A genome-wide association study for susceptibility to visual experience-induced myopia. Invest Ophthalmol Vis Sci. 2019;60(2):559–569. doi:10.1167/iovs.18-25597
  • Khor CC, Miyake M, Chen LJ, et al. Genome-wide association study identifies ZFHX1B as a susceptibility locus for severe myopia. Hum Mol Genet. 2013;22(25):5288–5294. doi:10.1093/hmg/ddt385
  • Meng W, Butterworth J, Bradley DT, et al. A genome-wide association study provides evidence for association of chromosome 8p23 (MYP10) and 10q21.1 (MYP15) with high myopia in the French Population. Invest Ophthalmol Vis Sci. 2012;53(13):7983–7988. doi:10.1167/iovs.12-10409
  • Li Z, Qu J, Xu X, et al. A genome-wide association study reveals association between common variants in an intergenic region of 4q25 and high-grade myopia in the Chinese Han population. Hum Mol Genet. 2011;20(14):2861–2868. doi:10.1093/hmg/ddr169
  • Solouki AM, Verhoeven VJ, van Duijn CM, et al. A genome-wide association study identifies a susceptibility locus for refractive errors and myopia at 15q14. Nat Genet. 2010;42(10):897–901. doi:10.1038/ng.663
  • Hysi PG, Young TL, Mackey DA, et al. A genome-wide association study for myopia and refractive error identifies a susceptibility locus at 15q25. Nat Genet. 2010;42(10):902–905. doi:10.1038/ng.664
  • Wang Q, Gao Y, Wang P, et al. Replication study of significant single nucleotide polymorphisms associated with myopia from two genome-wide association studies. Mol Vis. 2011;17:3290–3299.
  • Boyle AP, Hong EL, Hariharan M, et al. Annotation of functional variation in personal genomes using Regulome DB. Genome Res. 2012;22(9):1790–1797. doi:10.1101/gr.137323.112
  • Ward LD, Kellis M. HaploReg v4: systematic mining of putative causal variants, cell types, regulators and target genes for human complex traits and disease. Nucleic Acids Res. 2016;44(D1):D877–881. doi:10.1093/nar/gkv1340
  • Baird PN, Saw SM, Lanca C, et al. Myopia. Nat Rev Dis Primers. 2020;6(1):99.

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