Developments in administration of growth hormone treatment: focus on Norditropin^® Flexpro^®

References

• JohnsonRTGibbsCJJrCreutzfeldt-Jakob disease and related transmissible spongiform encephalopathiesN Engl J Med1998339199420049869672
   PubMed Web of Science ®Google Scholar
• FlodhHHuman growth hormone produced with recombinant DNA technology: Development and productionActa Paediatr Scand Suppl1986325193296632
   PubMedGoogle Scholar
• ZeiselHJvon PetrykowskiWWaisUPharmacokinetics and short-term metabolic effects of mammalian cell-derived biosynthetic human growth hormone in manHorm Res199237Suppl 25131490668
   PubMedGoogle Scholar
• DumasHPanayiotopoulosPParkerDPongpairochanaVUnderstanding and meeting the needs of those using growth hormone injection devicesBMC Endocr Disord20066517034628
   PubMedGoogle Scholar
• KrysiakRGdula-DymekABednarska-CzerwinskaAOkopienBGrowth hormone therapy in children and adultsPharmacol Rep20075950051618048950
   PubMed Web of Science ®Google Scholar
• HoKKConsensus guidelines for the diagnosis and treatment of adults with GH deficiency II: A statement of the GH Research Society in association with the European Society for Pediatric Endocrinology, Lawson Wilkins Society, European Society of Endocrinology, Japan Endocrine Society, and Endocrine Society of AustraliaEur J Endocrinol200715769570018057375
   PubMed Web of Science ®Google Scholar
• SmithSLHindmarshPCBrookCGCompliance with growth hormone treatment – are they getting itArch Dis Child19936891938435018
   PubMed Web of Science ®Google Scholar
• ZambaniniANewsonRBMaiseyMFeherMDInjection related anxiety in insulin-treated diabetesDiabetes Res Clin Pract19994623924610624790
   PubMed Web of Science ®Google Scholar
• CosteJLetraitMCarelJCLong-term results of growth hormone treatment in France in children of short stature: Population, register based studyBMJ19973157087139314755
   PubMed Web of Science ®Google Scholar
• HaverkampFJohanssonLDumasHObservations of nonadherence to recombinant human growth hormone therapy in clinical practiceClin Ther20083030731618343269
   PubMed Web of Science ®Google Scholar
• KapoorRRBurkeSASparrowSEMonitoring of concordance in growth hormone therapyArch Dis Child20089314714817768149
   PubMed Web of Science ®Google Scholar
• RosenfeldRGBakkerBCompliance and persistence in pediatric and adult patients receiving growth hormone therapyEndocr Pract20081414315418308651
   PubMedGoogle Scholar
• LanghamSKirkJNational audit of patient choice in pediatric GH therapyHorm Res Paediatr922010 [Epub ahead of print]
   Web of Science ®Google Scholar
• FidottiEA history of growth hormone injection devicesJ Pediatr Endocrinol Metab20011449750111393569
   PubMed Web of Science ®Google Scholar
• PellissierGMigueresBTarantolaAAbiteboulDLolomIBouvetERisk of needlestick injuries by injection pensJ Hosp Infect200663606416540200
   PubMed Web of Science ®Google Scholar
• MitragotriSCurrent status and future prospects of needle-free liquid jet injectorsNat Rev Drug Discov2006554354816816837
   PubMed Web of Science ®Google Scholar
• BristowAFGaines-DasRJeffcoateSLSchulsterDThe First International Standard for Somatropin: Report of an international collaborative studyGrowth Regul199551331417580864
   PubMedGoogle Scholar
• SerostimProduct information.Randolph, MAEMD Serono, Inc92007
   Google Scholar
• Tev-TropinProduct informationSellersville, PAGate Pharmaceuticals102007
   Google Scholar
• ZorbtiveProduct informationRockland, MAEMD Serono Inc12009
   Google Scholar
• HumatropeProduct informationIndianapolis, INEli Lilly and Company82009
   Google Scholar
• NutropinAQProduct informationSouth San Francisco, CAGenetech, Inc12008
   Google Scholar
• SaizenProduct informationRockland, MAEMD Serono, Inc92007
   Google Scholar
• NorditropinProduct informationPrinceton, NJNovo Nordisk Inc32010
   Google Scholar
• GenotropinProduct informationNew York, NYPfizer, Inc82009
   Google Scholar
• NutropinAQProduct informationSouth San Francisco, CAGenentech, Inc62006
   Google Scholar
• OmnitropeProduct informationPrinceton, NJSandoz, Inc62010
   Google Scholar
• HermanussenMGeiger-BenoitKSippellWGCatch-up growth following transfer from three times weekly im to daily sc administration of hGH in GH deficient patients, monitored by knemometryActa Endocrinol (Copenh)19851091631684013610
   PubMedGoogle Scholar
• JohanssonJOWirenLOscarssonJBengtssonBAJohannssonGGrowth hormone (GH) replacement in GH-deficient adults: A crossover trial comparing the effect on metabolic control, well-being and compliance of three injections per week versus daily injectionsGrowth Horm IGF Res20031330631514624763
   PubMed Web of Science ®Google Scholar
• Albertsson-WiklandKWestphalOWestgrenUDaily subcutaneous administration of human growth hormone in growth hormone deficient childrenActa Paediatr Scand19867589973513479
   PubMed Web of Science ®Google Scholar
• KastrupKWChristiansenJSAndersenJKOrskovHIncreased growth rate following transfer to daily sc administration from three weekly im injections of hGH in growth hormone deficient childrenActa Endocrinol (Copenh)19831041481526637329
   PubMedGoogle Scholar
• LaursenTJorgensenJOSusgaardSMollerJChristiansenJSSubcutaneous absorption kinetics of two highly concentrated preparations of recombinant human growth hormoneAnn Pharmacother1993274114158477114
   PubMed Web of Science ®Google Scholar
• ChungHJLeeYParkTGThermo-sensitive and biodegradable hydrogels based on stereocomplexed Pluronic multi-block copolymers for controlled protein deliveryJ Control Release2008127223018234389
   PubMed Web of Science ®Google Scholar
• GovardhanCKhalafNJungCWNovel long-acting crystal formulation of human growth hormonePharm Res2005221461147016132358
   PubMed Web of Science ®Google Scholar
• JohnsonOLClelandJLLeeHJA month-long effect from a single injection of microencapsulated human growth hormoneNat Med199627957998673926
   PubMed Web of Science ®Google Scholar
• JohnsonOLJaworowiczWClelandJLThe stabilization and encapsulation of human growth hormone into biodegradable microspheresPharm Res1997147307359210189
   PubMed Web of Science ®Google Scholar
• LeeENKimYMLeeHJStabilizing peptide fusion for solving the stability and solubility problems of therapeutic proteinsPharm Res2005221735174616180132
   PubMed Web of Science ®Google Scholar
• LeeHJRileyGJohnsonOIn vivo characterization of sustained-release formulations of human growth hormoneJ Pharmacol Exp Ther1997281143114399190880
   PubMed Web of Science ®Google Scholar
• TaeGKornfieldJAHubbellJASustained release of human growth hormone from in situ forming hydrogels using self-assembly of fluoroalkyl-ended poly(ethylene glycol)Biomaterials2005265259526615792553
   PubMed Web of Science ®Google Scholar
• ParkMRChunCAhnSWKiMHChoCSSongSCSustained delivery of human growth hormone using a polyelectrolyte complex-loaded thermosensitive polyphosphazene hydrogelJ Control Release201014735936720713099
   PubMed Web of Science ®Google Scholar
• BillerBMKJiHJLeeSTwelve months efficacy and safety of a novel once-a-week sustained release rhGH (LB03002): A Phase III study in adults with GH deficiencyPresented at the 92nd annual meeting of the Endocrine SocietySan Diego, CAJune 19–22, 2010
   Google Scholar
• BazaloGRJoshiAVGermakJComparison of human growth hormone products’ cost in pediatric and adult patients. A budgetary impact modelManag Care200716455117969748
   PubMedGoogle Scholar
• SolvigJChristansenJSLytzenLNeedle length affects insulin deposition in normal and obese diabetes patientsDiabetes Res Clin Pract200150Suppl 2A132
   Google Scholar
• PfutznerAHartmannKWinterFFuchsGSKappelgaardAMRohrerTRIntuitiveness, ease of use, and preference of a prefilled growth hormone injection pen: A noninterventional, randomized, open-label, crossover, comparative usability study of three delivery devices in growth hormone-treated pediatric patientsClin Ther2010321918193421095487
   PubMed Web of Science ®Google Scholar
• ShineBMusialWOwensLDeebLLuetjenTHowardCPatient and parent preference for growth hormone productsAm J Health Syst Pharm200360899012533983
   PubMed Web of Science ®Google Scholar
• FuchsGSMikkelsenSKnudsenTKKappelgaardAMEase of use and acceptability of a new pen device for the administration of growth hormone therapy in pediatric patients: An open-label, uncontrolled usability testClin Ther2009312906291420110030
   PubMed Web of Science ®Google Scholar
• KappelgaardAMMikkelsenSBaggerCFuchs GS Patient acceptability of a new injection device system to administer human growth hormone: Results from a multinational handling and questionnaire surveyPresented at the 92nd annual meeting of the Endocrine SocietySan Diego, CAJune 19–22, 2010
   Google Scholar
• KappelgaardAMMikkelsenSBaggerCKnudsenTKFuchsGSUsability testing of a new pen injector and a combination of the new pen injector and a new penmate system to administer human growth hormone in three open-label user surveysPresented at the 92nd annual meeting of the Endocrine SocietySan Diego, CAJune 19–22, 2010
   Google Scholar
• FrenchDMarket trends for injection devices for pharmaceuticals. Touch briefingsFuture Drug Delivery20062024
   Google Scholar
• BrearleyCPriestleyALeighton-ScottJChristenMPharmacokinetics of recombinant human growth hormone administered by cool.click 2, a new needle-free device, compared with subcutaneous administration using a conventional syringe and needleBMC Clin Pharmacol200771017922895
   PubMedGoogle Scholar
• EdwardsDAHanesJCaponettiGLarge porous particles for pulmonary drug deliveryScience1997276186818719188534
   PubMed Web of Science ®Google Scholar
• ChipmanJLucasRJacksonBPharmacokinetics and safety results of a human single dose comparison of somatropin inhalation powder vs subcutaneous injection of somatropinPresented at the 87th annual meeting of the Endocrine SocietySan Diego, CAJune 4–7, 2005
   Google Scholar
• WalvoordECde la PenaAParkSInhaled growth hormone (GH) compared with subcutaneous GH in children with GH deficiency: Pharmacokinetics, pharmacodynamics, and safetyJ Clin Endocrinol Metab2009942052205919336514
   PubMed Web of Science ®Google Scholar