SPUR: A Patient-Reported Medication Adherence Model as a Predictor of Admission and Early Readmission in Patients Living with Type 2 Diabetes

References

• Haynes RB, McKibbon KA, Kanani R. Systematic review of randomised trials of interventions to assist patients to follow prescriptions for medications. Lancet. 1996;348(9024):383–386. doi:10.1016/S0140-6736(96)01073-2
   PubMed Web of Science ®Google Scholar
• Eduardo Sabaté (WHO/NMH/CCH). Adherence to Long-Term Therapies: Policy for Action. World Health Organization (WHO); 2001.
   Google Scholar
• Cutler RL, Fernandez-Llimos F, Frommer M, Benrimoj C, Garcia-Cardenas V. Economic impact of medication non-adherence by disease groups: a systematic review. BMJ Open. 2018;8:1. doi:10.1136/BMJOPEN-2017-016982
   Web of Science ®Google Scholar
• Timmerman L, Stronks DL, Groeneweg JG, Huygen FJ. Prevalence and determinants of medication non-adherence in chronic pain patients: a systematic review. Acta Anaesthesiol Scand. 2016;60(4):416–431. doi:10.1111/AAS.12697
   PubMed Web of Science ®Google Scholar
• Cheen MHH, Tan YZ, Oh LF, Wee HL, Thumboo J. Prevalence of and factors associated with primary medication non-adherence in chronic disease: a systematic review and meta-analysis. Int J Clin Pract. 2019;73(6):e13350. doi:10.1111/IJCP.13350
   PubMed Web of Science ®Google Scholar
• Chapman SCE, Horne R. Medication nonadherence and psychiatry. Curr Opin Psychiatry. 2013;26(5):446. doi:10.1097/YCO.0B013E3283642DA4
   PubMed Web of Science ®Google Scholar
• Crawshaw J, Auyeung V, Norton S, Weinman J. Identifying psychosocial predictors of medication non-adherence following acute coronary syndrome: a systematic review and meta-analysis. J Psychosom Res. 2016;90:10–32. doi:10.1016/J.JPSYCHORES.2016.09.003
   PubMed Web of Science ®Google Scholar
• Foley L, Larkin J, Lombard-Vance R, et al. Prevalence and predictors of medication non-adherence among people living with multimorbidity: a systematic review and meta-analysis. BMJ Open. 2021;11:44987. doi:10.1136/bmjopen-2020-044987
   Web of Science ®Google Scholar
• Fischer MA, Stedman MR, Lii J, et al. Primary medication non-adherence: analysis of 195,930 electronic prescriptions. J Gen Intern Med. 2010;25(4):284–290. doi:10.1007/S11606-010-1253-9/TABLES/5
   PubMed Web of Science ®Google Scholar
• Yeam CT, Chia S, Tan HCC, Kwan YH, Fong W, Seng JJB. A systematic review of factors affecting medication adherence among patients with osteoporosis. Osteoporos Int. 2018;29(12):2623–2637. doi:10.1007/S00198-018-4759-3
   PubMed Web of Science ®Google Scholar
• Seng JJB, Tan JY, Yeam CT, Htay H, Foo WYM. Factors affecting medication adherence among pre-dialysis chronic kidney disease patients: a systematic review and meta-analysis of literature. Int Urol Nephrol. 2020;52(5):903–916. doi:10.1007/S11255-020-02452-8
   PubMed Web of Science ®Google Scholar
• Mongkhon P, Ashcroft DM, Scholfield CN, Kongkaew C. Hospital admissions associated with medication non-adherence: a systematic review of prospective observational studies. BMJ Qual Saf. 2018;27(11):902–914. doi:10.1136/BMJQS-2017-007453
   PubMed Web of Science ®Google Scholar
• Vestbo J, Anderson JA, Calverley PMA, et al. Adherence to inhaled therapy, mortality and hospital admission in COPD. Thorax. 2009;64(11):939–943. doi:10.1136/THX.2009.113662
   PubMed Web of Science ®Google Scholar
• Payero MÁ, Martínez López De CN, Samartín MU, Vila AM, Vázquez LC, Corrales GP. Medication non-adherence as a cause of hospital admissions. Farm Hosp. 2014;38(4):328–333. doi:10.7399/FH.2014.38.4.7660
   PubMedGoogle Scholar
• Department of Health. Payment by Results Guidance for 2011–12 [Internet]; 2011. Available from: http://webarchive.nationalarchives.gov.uk/20130507170152/https://www.gov.uk/government/uploads/system/uploads/attachment_data/file/151911/dh_126157.pdf.pdf. Accessed January 2, 2023.
   Google Scholar
• Ruppar TM, Cooper PS, Mehr DR, Delgado JM, Dunbar-Jacob JM. Medication adherence interventions improve heart failure mortality and readmission rates: systematic review and meta-analysis of controlled trials. J Am Heart Assoc. 2016;5:6. doi:10.1161/JAHA.115.002606
   Web of Science ®Google Scholar
• Readdean KC, Heuer AJ, Scott Parrott J. Effect of pharmacist intervention on improving antidepressant medication adherence and depression symptomology: a systematic review and meta-analysis. Res Social Adm Pharm. 2018;14(4):321–331. doi:10.1016/J.SAPHARM.2017.05.008
   PubMed Web of Science ®Google Scholar
• Leguelinel-Blache G, Dubois F, Bouvet S, et al. Improving patient’s primary medication adherence: the value of pharmaceutical counseling. Medicine. 2015;94:41. doi:10.1097/MD.0000000000001805
   Web of Science ®Google Scholar
• Verloo H, Chiolero A, Kiszio B, Kampel T, Santschi V. Nurse interventions to improve medication adherence among discharged older adults: a systematic review. Age Ageing. 2017;46(5):747–754. doi:10.1093/AGEING/AFX076
   PubMed Web of Science ®Google Scholar
• Delgado-Silveira E, Vélez-Díaz-Pallarés M, Muñoz-García M, Correa-Pérez A, Álvarez-Díaz AM, Cruz-Jentoft AJ. Effects of hospital pharmacist interventions on health outcomes in older polymedicated inpatients: a scoping review. Eur Geriatr Med. 2021;12(3):509–544. doi:10.1007/S41999-021-00487-3
   PubMed Web of Science ®Google Scholar
• Bach QN, Peasah SK, Barber E. Review of the role of the pharmacist in reducing hospital readmissions. J Pharm Pract. 2019;32(6):617–624. doi:10.1177/0897190018765500
   PubMed Web of Science ®Google Scholar
• Granger BB, Bosworth HB. Medication adherence: emerging use of technology. Curr Opin Cardiol. 2011;26(4):279. doi:10.1097/HCO.0B013E328347C150
   PubMed Web of Science ®Google Scholar
• Gandapur Y, Kianoush S, Kelli HM, et al. The role of mHealth for improving medication adherence in patients with cardiovascular disease: a systematic review. Eur Heart J Qual Care Clin Outcomes. 2016;2(4):237–244. doi:10.1093/EHJQCCO/QCW018
   PubMedGoogle Scholar
• Pal P, Sambhakar S, Dave V, et al. A review on emerging smart technological innovations in healthcare sector for increasing patient’s medication adherence. Global Health J. 2021;5(4):183–189. doi:10.1016/J.GLOHJ.2021.11.006
   Google Scholar
• Rosen OZ, Fridman R, Rosen BT, Shane R, Pevnick JM. Medication adherence as a predictor of 30-day hospital readmissions. Patient Prefer Adherence. 2017;11:801–810. doi:10.2147/PPA.S125672
   PubMed Web of Science ®Google Scholar
• Morisky DE, Green LW, Levine DM. Concurrent and predictive validity of a self-reported measure of medication adherence. Med Care. 1986;24(1):67–74. doi:10.1097/00005650-198601000-00007
   PubMed Web of Science ®Google Scholar
• Brown MT, Bussell JK. Medication adherence: WHO cares? Mayo Clin Proc. 2011;86(4). doi:10.4065/mcp.2010.0575
   Web of Science ®Google Scholar
• Gonzalez JS, Schneider HE. Methodological issues in the assessment of diabetes treatment adherence. Curr Diab Rep. 2011;11(6):472–479. doi:10.1007/S11892-011-0229-4
   PubMed Web of Science ®Google Scholar
• Wells J, Crilly P, Kayyali R, Systematic A. Analysis of reviews exploring the scope, validity, and reporting of patient-reported outcomes measures of medication adherence in type 2 diabetes. Patient Prefer Adherence. 2022;16:1941–1954. doi:10.2147/PPA.S375745
   PubMed Web of Science ®Google Scholar
• Mokkink Cecilia AC, Prinsen Donald L, Patrick Jordi LB, Mokkink CL. COSMIN Study Design checklist for Patient-reported outcome measurement instruments. Available from: www.cosmin.nl. Accessed April 16, 2022.
   Google Scholar
• Dolgin K. The SPUR model: a framework for considering patient behavior. Patient Prefer Adherence. 2020;14. doi:10.2147/PPA.S237778
   PubMed Web of Science ®Google Scholar
• Tugaut B, Shah S, Dolgin K, et al. Development of the SPUR tool: a profiling instrument for patient treatment behavior. J Patient Rep Outcomes. 2022;6(1):1–10. doi:10.1186/S41687-022-00470-X
   PubMedGoogle Scholar
• de Bock E, Dolgin K, Arnould B, Hubert G, Lee A, Piette JD. The SPUR adherence profiling tool: preliminary results of algorithm development. Curr Med Res Opin. 2021;38(2):171–179. doi:10.1080/03007995.2021.2010437
   PubMed Web of Science ®Google Scholar
• Bock E, Dolgin K, Kombargi L, et al. Finalization and validation of questionnaire and algorithm of SPUR, a new adherence profiling tool. Patient Prefer Adherence. 2022;16:1213–1231. doi:10.2147/PPA.S354705
   PubMed Web of Science ®Google Scholar
• Wells JS, Husseini A, Okoh S, et al. SPUR: psychometric properties of a patient-reported outcome measure of medication adherence in type 2 diabetes. BMJ Open. 2022;12(9):e058467. doi:10.1136/BMJOPEN-2021-058467
   PubMed Web of Science ®Google Scholar
• Vandenbroucke JP, von Elm E, Altman DG, et al. Strengthening the Reporting of Observational Studies in Epidemiology (STROBE): explanation and Elaboration. PLoS Med. 2007;4(10):e297. doi:10.1371/JOURNAL.PMED.0040297
   PubMed Web of Science ®Google Scholar
• Little M, Jordens CFC, Paul K, Montgomery K, Philipson B. Liminality: a major category of the experience of cancer illness. J Bioeth Inq. 2022;19(1):37–48. doi:10.1007/S11673-022-10175-X/METRICS
   PubMed Web of Science ®Google Scholar
• Thompson K, Kulkarni J, Sergejew AA. Reliability and validity of a new Medication Adherence Rating Scale (Mars) for the psychoses. Schizophr Res. 2000;42:3. doi:10.1016/S0920-9964(99)00130-9
   Web of Science ®Google Scholar
• Horne R, Weinman J. Patients’ beliefs about prescribed medicines and their role in adherence to treatment in chronic physical illness. J Psychosom Res. 1999;47:6. doi:10.1016/S0022-3999(99)00057-4
   Web of Science ®Google Scholar
• Bradley C, Lewis KS. Measures of psychological well‐being and treatment satisfaction developed from the responses of people with tablet‐treated diabetes. Diabetic Med. 1990;7:5. doi:10.1111/j.1464-5491.1990.tb01421.x
   Web of Science ®Google Scholar
• Vittinghoff E, McCulloch CE. Relaxing the rule of ten events per variable in logistic and cox regression. Am J Epidemiol. 2007;165(6):710–718. doi:10.1093/AJE/KWK052
   PubMed Web of Science ®Google Scholar
• van Calster B, van Smeden M, de Cock B, Steyerberg EW. Regression shrinkage methods for clinical prediction models do not guarantee improved performance: simulation study. Stat Methods Med Res. 2020;29(11):3166–3178. doi:10.1177/0962280220921415
   PubMed Web of Science ®Google Scholar
• Ahmadipour H, Farajzadegan Z, Kachoei A, Pirdehghan A. Secondary prevention by enhancing adherence in diabetic patients. Int J Prev Med. 2010;1:1. doi:10.4103/ijpvm.IJPVM_302_16
   PubMedGoogle Scholar
• Wang H, Zhao T, Wei X, Lu H, Lin X. The prevalence of 30-day readmission after acute myocardial infarction: a systematic review and meta-analysis. Clin Cardiol. 2019;42(10):889–898. doi:10.1002/CLC.23238
   PubMed Web of Science ®Google Scholar
• Kwok CS, Wong CW, Shufflebotham H, et al. Early readmissions after acute myocardial infarction. Am J Cardiol. 2017;120(5):723–728. doi:10.1016/J.AMJCARD.2017.05.049
   PubMed Web of Science ®Google Scholar
• Conway R, Byrne D, O’Riordan D, Silke B. Outcomes in acute medicine - Evidence from extended observations on readmissions, hospital length of stay and mortality outcomes. Eur J Intern Med. 2019;66:69–74. doi:10.1016/J.EJIM.2019.06.001
   PubMed Web of Science ®Google Scholar
• Shebehe J, Hansson A. High hospital readmission rates for patients aged ≥65 years associated with low socioeconomic status in a Swedish region: a cross-sectional study in primary care. Scand J Prim Health Care. 2018;36(3):300–307. doi:10.1080/02813432.2018.1499584
   PubMed Web of Science ®Google Scholar
• Rubin DJ, Recco D, Turchin A, Zhao H, Golden SH. External validation of the diabetes early re-admission risk indicator (Derri TM). Endocr Pract. 2018;24(6):527–541. doi:10.4158/EP-2018-0035
   PubMed Web of Science ®Google Scholar
• Huang CW, Desai PP, Wei KK, Liu ILA, Lee JS, Nguyen HQ. Characteristics of patients discharged and readmitted after COVID-19 hospitalisation within a large integrated health system in the United States. Infect Dis. 2021;53(10):800–804. doi:10.1080/23744235.2021.1924398
   PubMed Web of Science ®Google Scholar
• Nematshahi M, Soroosh D, Neamatshahi M, Attarian F, Rahimi F. Factors predicting readmission in patients with COVID-19. BMC Res Notes. 2021;14(1):1–6. doi:10.1186/S13104-021-05782-7
   PubMed Web of Science ®Google Scholar
• Huang R, Zhuid L, Xue L, et al. Clinical findings of patients with coronavirus disease 2019 in Jiangsu province, China: a retrospective, multi-center study. PLoS Negl Trop Dis. 2020;14(5):e0008280. doi:10.1371/JOURNAL.PNTD.0008280
   PubMed Web of Science ®Google Scholar
• Yeo I, Baek S, Kim J, et al. Assessment of thirty-day readmission rate, timing, causes and predictors after hospitalization with COVID-19. J Intern Med. 2021;290(1):157–165. doi:10.1111/JOIM.13241
   PubMed Web of Science ®Google Scholar
• Zheng Z, Peng F, Xu B, et al. Risk factors of critical & mortal COVID-19 cases: a systematic literature review and meta-analysis. J Infect. 2020;81(2):e16–e25. doi:10.1016/J.JINF.2020.04.021
   PubMed Web of Science ®Google Scholar
• Kwok S, Adam S, Hoong HJ, et al. Obesity: a critical risk factor in the COVID-19 pandemic. Clin Obes. 2020;10(6):e12403. doi:10.1111/COB.12403
   PubMed Web of Science ®Google Scholar
• Collins J, Abbass IM, Harvey R, et al. Predictors of all-cause 30 day readmission among Medicare patients with type 2 diabetes. Curr Med Res Opin. 2017;33(8):1517–1523. doi:10.1080/03007995.2017.1330258
   PubMed Web of Science ®Google Scholar
• Comino EJ, Harris MF, Islam MDF, et al. Impact of diabetes on hospital admission and length of stay among a general population aged 45 year or more: a record linkage study. BMC Health Serv Res. 2015;15(1):1–13. doi:10.1186/S12913-014-0666-2
   PubMedGoogle Scholar
• Rubin DJ. Hospital readmission of patients with diabetes. Curr Diab Rep. 2015;15(4):1–9. doi:10.1007/S11892-015-0584-7
   Web of Science ®Google Scholar
• Rubin D, Handorf E, McDonnell M. predicting early readmission risk among hospitalized patients with diabetes. Diabetes & Obesity Management; 2013. Available from: https://endo.confex.com/endo/2013endo/webprogram/Paper7796.html. Accessed October 9, 2022.
   Google Scholar
• Salgado T, Marques A, Geraldes L, Benrimoj S, Horne R, Fernandez-Llimos F. Cross-cultural adaptation of the beliefs about medicines questionnaire into Portuguese. Sao Paulo Med J. 2013;131(2):88–94. doi:10.1590/S1516-31802013000100018
   PubMed Web of Science ®Google Scholar
• Nyland JE, Raja-Khan NT, Bettermann K, et al. Diabetes, drug treatment, and mortality in COVID-19: a multinational retrospective cohort study. Diabetes. 2021;70(12):2903–2916. doi:10.2337/DB21-0385
   PubMed Web of Science ®Google Scholar
• van Calster B, McLernon DJ, van Smeden M, et al. Calibration: the Achilles heel of predictive analytics. BMC Med. 2019;17(1):1–7. doi:10.1186/S12916-019-1466-7
   PubMed Web of Science ®Google Scholar
• van Calster B, Vickers AJ. Calibration of risk prediction models: impact on decision-analytic performance. Med Decision Mak. 2015;35(2):162–169. doi:10.1177/0272989X14547233/ASSET/IMAGES/LARGE/10.1177_0272989X14547233
   PubMed Web of Science ®Google Scholar