Individual Differences in Hemispheric Emotional Valence by Computerized Test Correlate with Lateralized Differences in Nucleus Accumbens, Hippocampal and Amygdala Volumes

References

• Lee GP, Meador KJ, Loring DW, et al. Neural substrates of emotion as revealed by functional magnetic resonance imaging. Cogn Behav Neurol. 2004;17(1):9–17. doi:10.1097/00146965-200403000-00002
   PubMedGoogle Scholar
• Roesmann K, Dellert T, Junghoefer M, et al. The causal role of prefrontal hemispheric asymmetry in valence processing of words - Insights from a combined cTBS-MEG study. Neuroimage. 2019;191:367–379. doi:10.1016/j.neuroimage.2019.01.057
   PubMed Web of Science ®Google Scholar
• Gainotti G. Emotions and the right hemisphere: can new data clarify old models? Neuroscientist. 2019;25(3):258–270. doi:10.1177/1073858418785342
   PubMed Web of Science ®Google Scholar
• Packheiser J, Rook N, Dursun Z, et al. Embracing your emotions: affective state impacts lateralisation of human embraces. Psychol Res. 2019;83(1):26–36. doi:10.1007/s00426-018-0985-8
   PubMed Web of Science ®Google Scholar
• Gainotti G. A historical review of investigations on laterality of emotions in the human brain. J Hist Neurosci. 2019;28(1):23–41. doi:10.1080/0964704X.2018.1524683
   PubMed Web of Science ®Google Scholar
• Harmon-Jones E. Early Career Award. Clarifying the emotive functions of asymmetrical frontal cortical activity. Psychophysiology. 2003;40(6):838–848. doi:10.1111/1469-8986.00121
   PubMed Web of Science ®Google Scholar
• Harmon-Jones E. On motivational influences, moving beyond valence, and integrating dimensional and discrete views of emotion. Cogn Emot. 2019;33(1):101–108. doi:10.1080/02699931.2018.1514293
   PubMed Web of Science ®Google Scholar
• Schiffer F. Of Two Minds: Dual-Brain Psychology. 2nd ed. Amazon KDP; 2021.
   Google Scholar
• Schiffer F. Of Two Minds: The Revolutionary Science of Dual-Brain Psychology. The Free Press; 1998:243.
   Google Scholar
• Schiffer F. Unilateral transcranial photobiomodulation for opioid addiction in a clinical practice: a clinical overview and case series. J Psychiatr Res. 2021;133:134–141. doi:10.1016/j.jpsychires.2020.12.004
   PubMed Web of Science ®Google Scholar
• Schiffer F, Anderson CM, Teicher MH. Electroencephalogram, bilateral ear temperature, and affect changes induced by lateral visual field stimulation. Compr Psychiatry. 1999;40(3):221–225. doi:10.1016/S0010-440X(99)90007-X
   PubMed Web of Science ®Google Scholar
• Schiffer F, Glass I, Lord J, Teicher MH. Prediction of clinical outcomes from rTMS in depressed patients with lateral visual field stimulation: a replication. J Neuropsychiatry Clin Neurosci. 2008;20(2):194–200. doi:10.1176/jnp.2008.20.2.194
   PubMed Web of Science ®Google Scholar
• Schiffer F, Khan A, Bolger E, Flynn E, Seltzer WP, Teicher MH. An effective and safe novel treatment of opioid use disorder: unilateral transcranial photobiomodulation. Front Psychiatry. 2021;12:713686. doi:10.3389/fpsyt.2021.713686
   PubMed Web of Science ®Google Scholar
• Schiffer F, Mottaghy FM, Pandey Vimal RL, et al. Lateral visual field stimulation reveals extrastriate cortical activation in the contralateral hemisphere: an fMRI study. Psychiatry Res. 2004;131(1):1–9. doi:10.1016/j.pscychresns.2004.01.002
   PubMed Web of Science ®Google Scholar
• Schiffer F, Teicher MH, Anderson C, et al. Determination of hemispheric emotional valence in individual subjects: a new approach with research and therapeutic implications. Behav Brain Funct. 2007;3(1):13. doi:10.1186/1744-9081-3-13
   PubMed Web of Science ®Google Scholar
• Schiffer F, Teicher MH, Papanicolaou AC. Evoked potential evidence for right brain activity during the recall of traumatic memories. J Neuropsychiatry Clin Neurosci. 1995;7:169–175.
   PubMed Web of Science ®Google Scholar
• Schiffer F, Zaidel E, Bogen J, Chasan-Taber S. Different psychological status in the two hemispheres of two split-brain patients. Neuropsychiatry Neuropsychol Behav Neurol. 1998;11(3):151–156.
   PubMedGoogle Scholar
• Schiffer F, Reichmann W, Flynn E, Hamblin MR, McCormack H. A novel treatment of opioid cravings with an effect size of 73 for unilateral transcranial photobiomodulation over sham. Front Psychiatry. 2020;11:827. doi:10.3389/fpsyt.2020.00827
   PubMed Web of Science ®Google Scholar
• Schiffer F, Stinchfield Z, Pascual-Leone A. Prediction of clinical response to transcranial magnetic stimulation for depression by baseline lateral visual-field stimulation. Neuropsychiatry Neuropsychol Behav Neurol. 2002;15(1):18–27.
   PubMedGoogle Scholar
• Wittling W, Roschmann R. Emotion-related hemisphere asymmetry: subjective emotional responses to laterally presented films. Cortex. 1993;29(3):431–448. doi:10.1016/s0010-9452(13)80252-3
   PubMed Web of Science ®Google Scholar
• Wittling W, Schweiger E. Neuroendocrine brain asymmetry and physical complaints. Neuropsychologia. 1993;31(6):591–608. doi:10.1016/0028-3932(93)90054-4
   PubMed Web of Science ®Google Scholar
• Sperry RW, Zaidel E, Zaidel D. Self recognition and social awareness in the deconnected minor hemisphere. Neuropsychologia. 1979;17(2):153–166. doi:10.1016/0028-3932(79)90006-X
   PubMed Web of Science ®Google Scholar
• Zaidel E, Zaidel DW, Sperry RW. Left and right intelligence: case studies of Raven’s progressive matrices following brain bisection and hemidecortication. Cortex. 1981;17(2):167–185. doi:10.1016/S0010-9452(81)80039-1
   PubMed Web of Science ®Google Scholar
• Schiffer F, Zaidel E, Bogen J, Chasan-Taber S. Different psychological status in the two hemispheres of two split brain patients. Neuropsychiatry Neuropsychol Behav Neurol. 1998;11(3):151–156.
   PubMedGoogle Scholar
• Schiffer F. Can the different cerebral hemispheres have distinct personalities? Evidence and its implications for theory and treatment of PTSD and other disorders. J Trauma Dissociation. 2000;1(2):83–104. doi:10.1300/J229v01n02_06
   Google Scholar
• Pascual-Leone A, Rubio B, Pallardo F, Catala MD. Rapid-rate transcranial magnetic stimulation of left dorsolateral prefrontal cortex in drug-resistant depression. Lancet. 1996;348(9022):233–237. doi:10.1016/S0140-6736(96)01219-6
   PubMed Web of Science ®Google Scholar
• Oathes DJ, Patenaude B, Schatzberg AF, Etkin A. Neurobiological signatures of anxiety and depression in resting-state functional magnetic resonance imaging. Biol Psychiatry. 2015;77(4):385–393. doi:10.1016/j.biopsych.2014.08.006
   PubMed Web of Science ®Google Scholar
• Teicher MH, Samson JA, Anderson CM, Ohashi K. The effects of childhood maltreatment on brain structure, function and connectivity. Nat Rev Neurosci. 2016;17(10):652–666. doi:10.1038/nrn.2016.111
   PubMed Web of Science ®Google Scholar
• Gong L, Yin Y, He C, et al. Disrupted reward circuits is associated with cognitive deficits and depression severity in major depressive disorder. J Psychiatr Res. 2017;84:9–17. doi:10.1016/j.jpsychires.2016.09.016
   PubMed Web of Science ®Google Scholar
• Ohashi K, Anderson CM, Bolger EA, Khan A, McGreenery CE, Teicher MH. Susceptibility or resilience to maltreatment can be explained by specific differences in brain network architecture. Biol Psychiatry. 2019;85(8):690–702. doi:10.1016/j.biopsych.2018.10.016
   PubMed Web of Science ®Google Scholar
• Schiffer F, Teicher M, Anderson C, et al. Determination of hemispheric emotional valence in individual subjects: a new approach with research and therapeutic implications. Behav Brain Funct. 2007;3(1):13. doi:10.1186/1744-9081-3-13
   PubMed Web of Science ®Google Scholar
• Teicher MH, Anderson CM, Ohashi K, Polcari A. Childhood maltreatment: altered network centrality of cingulate, precuneus, temporal pole and insula. Biol Psychiatry. 2014;76(4):297–305. doi:10.1016/j.biopsych.2013.09.016
   PubMed Web of Science ®Google Scholar
• Teicher MH, Anderson CM, Polcari A. Childhood maltreatment is associated with reduced volume in the hippocampal subfields CA3, dentate gyrus, and subiculum. Proc Natl Acad Sci U S A. 2012;109(9):E563–72. doi:10.1073/pnas.1115396109
   PubMed Web of Science ®Google Scholar
• Peirce JW. PsychoPy–psychophysics software in python. J Neurosci Methods. 2007;162(1–2):8–13. doi:10.1016/j.jneumeth.2006.11.017
   PubMed Web of Science ®Google Scholar
• Peirce JW. Generating stimuli for neuroscience using psychopy. Front Neuroinform. 2008;2:10. doi:10.3389/neuro.11.010.2008
   PubMed Web of Science ®Google Scholar
• Teicher MH, Parigger A. The ‘Maltreatment and Abuse Chronology of Exposure’ (MACE) scale for the retrospective assessment of abuse and neglect during development. PLoS One. 2015;10(2):e0117423. doi:10.1371/journal.pone.0117423
   PubMed Web of Science ®Google Scholar
• Felitti VJ, Anda RF, Nordenberg D, et al. Relationship of childhood abuse and household dysfunction to many of the leading causes of death in adults. The Adverse Childhood Experiences (ACE) Study. Am J Prev Med. 1998;14(4):245–258. doi:10.1016/S0749-3797(98)00017-8
   PubMed Web of Science ®Google Scholar
• Bernstein DP, Fink L. Childhood Trauma Questionnaire Manual. The Psychological Corporation; 1998.
   Google Scholar
• First MB, Gibbon M, Spitzer RL, Williams JBW, Benjamin LS. Structured Clinical Interview for DSM–IV Axis II Personality Disorders. American Psychiatric Association; 1997.
   Google Scholar
• First MB, Spitzer RL, Gibbon M, Williams JBW. Structured Clinical Interview for DSM-IV Axis I Disorders - Clinician Version (SCID-CV). American Psychiatric Press; 1997.
   Google Scholar
• Costa PTJ, McCrae RR. Revised NEO Personality Inventory (NEO-PI-R) and NEO Five-Factor Inventory (NEO-FF1) Professional Manual. Psychological Assessment Resources; 1992.
   Google Scholar
• McCrae RR, Costa PT Jr. NEO Inventories: Professional Manual. Psychological Assessment Resources, Inc.; 2010.
   Google Scholar
• Fischl B, Dale AM. Measuring the thickness of the human cerebral cortex from magnetic resonance images. Proc Natl Acad Sci U S A. 2000;97(20):11050–11055. doi:10.1073/pnas.200033797
   PubMed Web of Science ®Google Scholar
• Dale AM, Fischl B, Sereno MI. Cortical surface-based analysis. I. Segmentation and surface reconstruction. Neuroimage. 1999;9(2):179–194. doi:10.1006/nimg.1998.0395
   PubMed Web of Science ®Google Scholar
• Fischl B, Salat DH, van der Kouwe AJ, et al. Sequence-independent segmentation of magnetic resonance images. Neuroimage. 2004;23(Suppl 1):S69–84. doi:10.1016/j.neuroimage.2004.07.016
   PubMed Web of Science ®Google Scholar
• Segonne F, Dale AM, Busa E, et al. A hybrid approach to the skull stripping problem in MRI. Neuroimage. 2004;22(3):1060–1075. doi:10.1016/j.neuroimage.2004.03.032
   PubMed Web of Science ®Google Scholar
• Fischl B, van der Kouwe A, Destrieux C, et al. Automatically parcellating the human cerebral cortex. Cereb Cortex. 2004;14(1):11–22. doi:10.1093/cercor/bhg087
   PubMed Web of Science ®Google Scholar
• Fischl B, Salat DH, Busa E, et al. Whole brain segmentation: automated labeling of neuroanatomical structures in the human brain. Neuron. 2002;33(3):341–355. doi:10.1016/S0896-6273(02)00569-X
   PubMed Web of Science ®Google Scholar
• Fischl B, Liu A, Dale AM. Automated manifold surgery: constructing geometrically accurate and topologically correct models of the human cerebral cortex. IEEE Trans Med Imaging. 2001;20(1):70–80. doi:10.1109/42.906426
   PubMed Web of Science ®Google Scholar
• Dale AM, Sereno MI. Improved localization of cortical activity by combining EEG and MEG with MRI cortical surface reconstruction: a linear approach. J Cogn Neurosci. 1993;5(2):162–176. doi:10.1162/jocn.1993.5.2.162
   PubMed Web of Science ®Google Scholar
• Sled JG, Zijdenbos AP, Evans AC. A nonparametric method for automatic correction of intensity nonuniformity in MRI data. IEEE Trans Med Imaging. 1998;17(1):87–97. doi:10.1109/42.668698
   PubMed Web of Science ®Google Scholar
• Segonne F, Pacheco J, Fischl B. Geometrically accurate topology-correction of cortical surfaces using nonseparating loops. IEEE Trans Med Imaging. 2007;26(4):518–529. doi:10.1109/TMI.2006.887364
   PubMed Web of Science ®Google Scholar
• Ohashi K, Anderson CM, Bolger EA, Khan A, McGreenery CE, Teicher MH. Childhood maltreatment is associated with alteration in global network fiber-tract architecture independent of history of depression and anxiety. Neuroimage. 2017;150:50–59. doi:10.1016/j.neuroimage.2017.02.037
   PubMed Web of Science ®Google Scholar
• Gong G, He Y, Concha L, et al. Mapping anatomical connectivity patterns of human cerebral cortex using in vivo diffusion tensor imaging tractography. Cereb Cortex. 2009;19(3):524–536. doi:10.1093/cercor/bhn102
   PubMed Web of Science ®Google Scholar
• Li Y, Liu Y, Li J, et al. Brain anatomical network and intelligence. PLoS Comput Biol. 2009;5(5):e1000395. doi:10.1371/journal.pcbi.1000395
   PubMed Web of Science ®Google Scholar
• Tzourio-Mazoyer N, Landeau B, Papathanassiou D, et al. Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single-subject brain. Neuroimage. 2002;15(1):273–289. doi:10.1006/nimg.2001.0978
   PubMed Web of Science ®Google Scholar
• Wang R, Benner T, Sorensen AG, Wedeen V. Diffusion toolkit: a software package for diffusion imaging data processing and tractography. ISMRM Abstract Proc Intl Soc Mag Reson Med. 2007;15:3720.
   Google Scholar
• Csardi G, Nepusz T. The igraph software package for complex network research. Int J Complex Syst. 2006;1695:1–9.
   Google Scholar
• Grömping U. Estimators of relative importance in linear regression based on variance decomposition. Am Stat. 2007;61(2):139–147. doi:10.1198/000313007X188252
   Web of Science ®Google Scholar
• Lindeman RH, Merenda PF, Gold RZ. Introduction to Bivariate and Multivariate Analysis. Scott, Foresman; 1980.
   Google Scholar
• Strobl C, Boulesteix AL, Zeileis A, Hothorn T. Bias in random forest variable importance measures: illustrations, sources and a solution. BMC Bioinform. 2007;8(1):25. doi:10.1186/1471-2105-8-25
   PubMed Web of Science ®Google Scholar
• Khan A, McCormack HC, Bolger EA, et al. Childhood maltreatment, depression, and suicidal ideation: critical importance of parental and peer emotional abuse during developmental sensitive periods in males and females. Front Psychiatry. 2015;6:42. doi:10.3389/fpsyt.2015.00042
   PubMed Web of Science ®Google Scholar
• Teicher MH, Anderson CM, Ohashi K, et al. Differential effects of childhood neglect and abuse during sensitive exposure periods on male and female hippocampus. Neuroimage. 2018;169:443–452. doi:10.1016/j.neuroimage.2017.12.055
   PubMed Web of Science ®Google Scholar
• Pechtel P, Lyons-Ruth K, Anderson CM, Teicher MH. Sensitive periods of amygdala development: the role of maltreatment in preadolescence. Neuroimage. 2014;97:236–244. doi:10.1016/j.neuroimage.2014.04.025
   PubMed Web of Science ®Google Scholar
• Breiman L. Random Forests. Mach Learn. 2001;45:5–32.
   Web of Science ®Google Scholar
• Liaw A, Wiener M. Classification and Regression by randomForest. R News. 2002;2/3:18–22.
   Google Scholar
• Widiger TA, Crego C. The five factor model of personality structure: an update. World Psychiatry. 2019;18(3):271–272. doi:10.1002/wps.20658
   PubMed Web of Science ®Google Scholar
• Jenkins LM, Stange JP, Barba A, et al. Integrated cross-network connectivity of amygdala, insula, and subgenual cingulate associated with facial emotion perception in healthy controls and remitted major depressive disorder. Cogn Affect Behav Neurosci. 2017;17(6):1242–1254. doi:10.3758/s13415-017-0547-3
   PubMed Web of Science ®Google Scholar
• Forbes EE, Hariri AR, Martin SL, et al. Altered striatal activation predicting real-world positive affect in adolescent major depressive disorder. Am J Psychiatry. 2009;166(1):64–73. doi:10.1176/appi.ajp.2008.07081336
   PubMed Web of Science ®Google Scholar
• Berridge KC, Kringelbach ML. Neuroscience of affect: brain mechanisms of pleasure and displeasure. Curr Opin Neurobiol. 2013;23(3):294–303. doi:10.1016/j.conb.2013.01.017
   PubMed Web of Science ®Google Scholar
• Redlich R, Grotegerd D, Opel N, et al. Are you gonna leave me? Separation anxiety is associated with increased amygdala responsiveness and volume. Soc Cogn Affect Neurosci. 2015;10(2):278–284. doi:10.1093/scan/nsu055
   PubMed Web of Science ®Google Scholar
• Soares JM, Marques P, Alves V, Sousa N. A hitchhiker’s guide to diffusion tensor imaging. Front Neurosci. 2013;7:31. doi:10.3389/fnins.2013.00031
   PubMed Web of Science ®Google Scholar
• Luders E, Narr KL, Bilder RM, et al. Positive correlations between corpus callosum thickness and intelligence. Neuroimage. 2007;37(4):1457–1464. doi:10.1016/j.neuroimage.2007.06.028
   PubMed Web of Science ®Google Scholar
• Schiffer F, Stinchfield Z, Pascual-Leone A. Prediction of clinical response to transcranial magnetic stimulation for depression by baseline lateral visual stimulation. Neuropsychiatry Neuropsychol Behav Neurol. 2002;15(1):18–27.
   PubMedGoogle Scholar
• Schiffer F. A dual mind approach to understanding the conscious self and its treatment. Neuroscience. 2021;2(2):224–234. doi:10.3390/neurosci2020016
   Google Scholar