The ongoing debate over fetal anatomic surveys in the first trimester: a matter of timing?

References

• Nicolaides KH. A model for a new pyramid of prenatal care, based on the 11–13 weeks’ assessment. Prenat Diagn. 2011;31(1):3–6.
   PubMed Web of Science ®Google Scholar
• Borrell A, Grande M, Bennasar M, et al. First-trimester detection of major cardiac defects with use of ductus venosus blood flow. Ultrasound Obstet Gynecol. 2013;42(1):51–57.
   Web of Science ®Google Scholar
• Luchi C, Schifano M, Sacchini C, et al. Detailed fetal anatomy assessment in the first-trimester at 11,12 and 13 weeks of gestation. J Matern Fetal Neonatal Med. 2012;25(6):675–678.
   PubMed Web of Science ®Google Scholar
• Ghi T, Pilu G, Savelli L, Segata M, Bovicelli L. Sonographic diagnosis of Congenital anomalies during the first trimester. Placenta. 2003;24 Suppl B:S84–S87.
   Web of Science ®Google Scholar
• Gorlin RJ, Cervenka J, Pruzansky S. Facial clefting and its syndromes. Birth Defects Orig Artic Ser. 1971;7(7):3–49.
   Google Scholar
• Stoll C, Alembik Y, Dott B, Roth MP. Associated malformations in cases with oral clefts. Cleft Palate Craniofac J. 2000;37(1):41–47.
   Web of Science ®Google Scholar
• Sepulveda W, Wong AE, Martinez-Ten P, Perez-Pedregosa J. Retronasal triangle: a sonographic landmark for the screening of cleft palate in the first trimester. Ultrasound Obstet Gynecol. 2010;35(1):7–13.
   Web of Science ®Google Scholar
• Martinez-Ten P, Adiego B, Illescas T, Bermejo C, Wong AE, Seulveda W. First trimester diagnosis of cleft lip and palate using three-dimensional ultrasound. Ultrasound Obstet Gynecol. 2012;40(1):40–46.
   Web of Science ®Google Scholar
• Sepulveda W, Wong AE, Vinals F, Andreeva E, Adzehova N, Martinez-Ten P. Absent mandibular gap in the retronasal triangle view: a clue to the diagnosis of micrognathia in the first trimester. Ultrasound Obstet Gynecol. 2012;39(2):152–156.
   Web of Science ®Google Scholar
• Gardner E, O’Rahilly R, Prolo D. The Dandy-Walker and Arnold-Chiari malformations. Arch Neurol. 1975;32(6):393–407.
   Google Scholar
• Nicolaides KH, Campbell S, Gabbe SG, Guidetti R. Ultrasound screening for spina bifida: cranial and cerebellar signs. Lancet. 1986;2(8498):72–74.
   PubMed Web of Science ®Google Scholar
• Van den Hof MC, Nicolaides KH, Campbell J, Campbell S. Evaluation of the lemon and banana signs in one hundred and thirty fetuses with open spina bifida. Am J Obstet Gynecol. 1990;162(2):322–327.
   Web of Science ®Google Scholar
• Ghi T, Pilu G, Falco P, et al. Prenatal diagnosis of open and closed spina bifida. Ultrasound Obstet Gynecol. 2006;28(7):899–903.
   Web of Science ®Google Scholar
• Chaoui R, Benoit B, Mitkowska-Wozniak H, Heling KS, Nicolaides KH. Assessment of intracranial translucency (IT) in the detection of spina bifida at the 11–13-week scan. Ultrasound Obstet Gynecol. 2009;34(3):249–252.
   PubMed Web of Science ®Google Scholar
• Lachmann R, Chaoui R, Moratalla J, Picciarelli G, Nicolaides KH. Posterior brain in fetuses with open spina bifida at 11 to 13 weeks. Prenat Diagn. 2011;31(1):103–106.
   PubMed Web of Science ®Google Scholar
• Bernard JP, Cuckle HS, Stirnemann JJ, Salomon LJ, Ville Y. Screening for fetal spina bifida by ultrasound examination in the first trimester of pregnancy using fetal biparietal diameter. Am J Obstet Gynecol. 2012;207(4):306. e1–e5.
   Web of Science ®Google Scholar
• Loureiro T, Ushakov F, Montenegro N, Gielchincky Y, Nicolaides KH. Cerebral ventricular system in fetuses with open spina bifida at 11–13 weeks’ gestation. Ultrasound Obstet Gynecol. 2012;39(6):620–624.
   PubMed Web of Science ®Google Scholar
• Chen M, Lee CP, Lam YH, et al. Comparison of nuchal and detailed morphology ultrasound examinations in early pregnancy for fetal structural abnormality screening: a randomized controlled trial. Ultrasound Obstet Gynecol. 2008;31(2):136–146.
   PubMed Web of Science ®Google Scholar
• Sepulveda W, Dezerega V, Be C. First-trimester sonographic diagnosis of holoprosencephaly: value of the “butterfly” sign. J Ultrasound Med. 2004;23(6):761–765.
   Web of Science ®Google Scholar
• Luchi C, Monacci F, Schifano M, Gadducci A. ‘Bat-like’ choroid plexus and other sonographic features in trisomy 22 at the first trimester of pregnancy. Prenat Diagn. 2013;33(10):1013–1014.
   Web of Science ®Google Scholar
• Bronshtein M, Ben-Shlomo I. Choroid plexus dysmorphism detected by transvaginal sonography: the earliest sign of fetal hydrocephalus. J Clin Ultrasound. 1991;19(9):547–553.
   Web of Science ®Google Scholar
• Pooh RK. Imaging diagnosis of congenital brain anomalies and injuries. Semin Fetal Neonatal Med. 2012;17(6):360–376.
   Web of Science ®Google Scholar
• Seligman NS. Ultrasound for Fetal Ventriculomegaly: Review Article. Ultrasound Clinics. 2013;8(1):13–25.
   Google Scholar
• Kurjak A, Kupesic S, Matijevic R, Kos M, Marton Ulla. First Trimester malformation screening. European Journal of Obstetrics and Gynecology and Reproductive Biology. 1999;85(1):93–96.
   Web of Science ®Google Scholar
• van Zalen-Sprock RM, Van Vugt JM, Van Geijn HP. First and second trimester diagnosis of anomalies of the central nervous system. J Ultrasound Med. 1995;14(8):603–610.
   Web of Science ®Google Scholar
• Loureiro T, Ushakov F, Montenegro N, Nicolaides KH. Lateral ventricles in fetuses with aneuploidies at 11–13 weeks’ gestation. Ultrasound Obstet Gynecol. 2012;40(3):282–287.
   PubMed Web of Science ®Google Scholar
• Khairy MA, Shazly SA, Ali H, AbdelbadeeAY, Abbas AM. Ultrasonographic soft markers of aneuploidy in the second-trimester fetuses. Middle East Fertility Society Journal. 2012;17(3):145–151.
   Google Scholar
• Garcia-Posada R, Eixarch E, Sanz M, Puerto B, Figueras F, Borrell A. Cisterna magna width at 11–13 weeks in the detection of posterior fossa anomalies. Ultrasound Obstet Gynecol. 2013;41(5):515–520.
   Web of Science ®Google Scholar
• Mensah GA, Brown DW. An overview of cardiovascular disease burden in the United States. Health Aff (Millwood). 2007;26(1):38–48.
   PubMed Web of Science ®Google Scholar
• Hoffman JI. Incidence of congenital heart disease: II. Prenatal incidence. Pediatr Cardiol. 1995;16(4):155–165.
   PubMed Web of Science ®Google Scholar
• Nicolaides KH. A model for a new pyramid of prenatal care, based on the 11–13 weeks’ assessment. Prenat Diagn. 2011;31(1):3–6.
   PubMed Web of Science ®Google Scholar
• Rasiah SV, Publicover M, Ewer AK, Khan KS, Kilby MD, Zamora J. A systematic review of the accuracy of first-trimester ultrasound examination for detecting major congenital heart disease. Ultrasound Obstet Gynecol. 2006;28(1):110–116.
   Web of Science ®Google Scholar
• Volpe P, Ubaldo P, Volpe N, et al. Fetal cardiac evaluation at 11–14 weeks by experienced obstetricians in a low-risk population. Prenat Diagn. 2011;31(11):1054–1061.
   Web of Science ®Google Scholar
• Simpson JM, Jones A, Callaghan N, Sharland GK. Accuracy and limitations of transabdominal fetal echocardiography at 12–15 weeks of gestation in a population at high risk for congenital heart disease. BJOG. 2000;107(12):1492–1497.
   Google Scholar
• Westin M, Saltvedt S, Bergman G, et al. Routine ultrasound examination at 12 or 18 gestational weeks for prenatal detection of major congenital heart malformations? A randomised controlled trial comprising 36,299 fetuses. BJOG. 2006;113(6):675–682.
   Web of Science ®Google Scholar
• Kahil A, Nicholaides KH. Fetal heart defects: Potential and pitfalls of first-trimester detection. Semin Fetal Neonatal Med. 2013;18(5):251–260.
   Web of Science ®Google Scholar
• Syngelaki A, Chelemen T, Dagklis T, Allan L, Nicolaides KH. Challenges in the diagnosis of fetal non-chromosomal abnormalities at 11–13 weeks. Prenat Diagn. 2011;31(1):90–102.
   PubMed Web of Science ®Google Scholar
• Allan L, Cook A, Huggon I. First trimester fetal heart scanning. In: Allan L, Cook A, Huggon I, editors. Fetal Echocardiography a Practical Guide. New York: Cambridge University Press; 2009:190–202.
   Google Scholar
• Clur SA, Ottenkamp J, Bilardo CM. The nuchal translucency and the fetal heart: a literature review. Prenat Diagn. 2009;29(8):739–748.
   PubMed Web of Science ®Google Scholar
• Makrydimas G, Sotiriadis A, Hugon IC, et al. Nuchal translucency and fetal cardiac defects: a pooled analysis of major fetal echocardiography centers. Am J Obstet Gynecol. 2005;192(1):89–95.
   Web of Science ®Google Scholar
• Snijders RJ, Noble P, Sebire NJ, Souka AP, Nicolaides KH. UK multicentre project on assessment of risk of trisomy 21 by maternal age and fetal nuchal-translucency thickness at 10–14 weeks of gestation. Fetal Medicine Foundation First Trimester Screening Group. Lancet. 1998;352(9125):343–346.
   PubMed Web of Science ®Google Scholar
• Atzei A, Gajewska K, Huggon IC, Allan L, Nicolaides KH. Relation between nuchal translucency thickness and prevalence of major cardiac defects in fetuses with normal karyotype. Ultrasound Obstet Gynecol. 2005;26(2):154–157.
   Web of Science ®Google Scholar
• Pereira S, Ganapathy R, Syngelaki A, Maiz N, Nicolaides KH. Contribution of fetal tricuspid regurgitation in first-trimester screening for major cardiac defects. Obstet Gynecol. 2011;117(6):1384–1391.
   PubMed Web of Science ®Google Scholar
• Jelliffe-Pawlowski L, Baer R, Moon-Grady AJ, Currier RJ. Second trimester serum predictors of congenital heart defects in pregnancies without chromosomal or neural tube defects. Prenat Diagn. 2011;31(5):466–472.
   Web of Science ®Google Scholar
• Montenegro N, Matias A, Arejas JC, Barros H. Ductus venosus revisited: a Doppler blood flow evaluation in the first trimester of pregnancy. Ultrasound Med Biol. 1997;23(2):171–176.
   Web of Science ®Google Scholar
• Kiserud T, Stratford L, Hanson JA. Umbilical flow distribution to the liver and the ductus venosus: An in vitro investigation of the fluid dynamic mechanisms in the fetal sheep. Am J Obstet Gynecol. 1997; 177(1):86–90.
   Web of Science ®Google Scholar
• Matias A, Gomes C, Flack N, Montenegro N, Nicolaides KH. Screening for chromosomal abnormalities at 10–14 weeks: the role of ductus venosus blood flow. Ultrasound Obstet Gynecol. 1998;12(6):380–384.
   PubMed Web of Science ®Google Scholar
• Maiz N, Wright D, Ferreira AF, Syngelaki A, Nicolaides KH. A mixture model of ductus venosus pulsatility index in screening of aneuploidies at 11–13 weeks’ gestation. Fetal Diagn Ther. 2012;31(4):221–229.
   PubMed Web of Science ®Google Scholar
• Martinez JM, Comas M, Borrell A, et al. Abnormal first-trimester ductus venosus blood flow: a marker of cardia defects in fetuses with normal karyotype and nuchal translucency. Ultrasound Obstet Gynecol. 2010;35(3):267–272.
   PubMed Web of Science ®Google Scholar
• Papatheodorou SI, Evangelou E, Makrydimas G, Ioannidis JP. First-trimester ductus venosus screening for cardiac defects: a meta-analyses. BJOG. 2011;118(12):1438–1445.
   PubMed Web of Science ®Google Scholar
• Borrell A, Grande M, Bennasar M, et al. First-trimester detection of major cardiac defects with use of ductus venosus blood flow. Ultrasound Obstet Gynecol. 2013;42(1):51–57.
   Web of Science ®Google Scholar
• Contratti G, Banzi C, Ghi T, Perolo A, Pilu G, Visentin A. Absence of the ductus venosus: report of 10 new cases and review of the literature. Ultrasound Obstet Gynecol. 2001;18(6):605–609.
   PubMed Web of Science ®Google Scholar
• Staboulidou I, Pereira S, Cruz Jde J, Syngelaki A, Nicolaides KH. Prevalence and outcome of absence of ductus venosus at 11 (+0) to 13 (+6) weeks. Fetal Diagn Ther. 2011;30(1):35–40.
   Web of Science ®Google Scholar
• Berg C, Kamil D, Geipel A, et al. Absence of ductus venosus-importance of umbilical venous drainage site. Ultrasound Obstet Gynecol. 2006;28(3):275–281.
   PubMed Web of Science ®Google Scholar
• Kagan KO, Valencia C, Livanos P, Wright D, Nicolaides KH. Tricuspid regurgitation in screening for trisomies 21, 18 and 13 and Turner syndrome at 11 +0 to 13 +6 weeks of gestation. Ultrasound Obstet Gynecol. 2008;33(1):18–22.
   Web of Science ®Google Scholar
• Falcon O, Faiola S, Huggon I, Allan L, Nicolaides KH. Fetal tricuspid regurgitation at the 11 + 0 to 13 + 6-week scan: association with chromosomal defects and reproducibility of the method. Ultrasound Obstet Gynecol. 2006;27(6):609–612.
   PubMed Web of Science ®Google Scholar
• Kagan KO, Valencia C, Livanos P, Wright D, Nicolaides KH. Tricuspid regurgitation in screening for trisomies 21, 18 and 13 and Turner syndrome at 11 +0 to 13 +6 weeks of gestation. Ultrasound Obstet Gynecol. 2008;33(1):18–22.
   Web of Science ®Google Scholar
• Persico N, Moratalla J, Lombardi CM, Zidere V, Allan L, Nicolaides KH. Fetal echocardiography at 11–13 weeks by transabdominal high-frequency ultrasound. Ultrasound Obstet Gynecol. 2011;37(3):296–301.
   PubMed Web of Science ®Google Scholar
• Pereira S, Ganapathy R, Syngelaki A, Maiz N, Nicolaides KH. Contribution of fetal tricuspid regurgitation in first-trimester screening for major cardiac defects. Obstet Gynecol. 2011;117(6):1384–1391.
   PubMed Web of Science ®Google Scholar
• Yagel S, Arbel R, Anteby EY, Raveh D, Achiron R. The three vessels and trachea view (3VT) in fetal cardiac scanning. Ultrasound Obstet Gynecol. 2002;20(4):340–345.
   PubMed Web of Science ®Google Scholar
• Zapata H, Edwards JE, Titus JL. Aberrant right subclavian artery with left aortic arch: associated cardiac anomalies. Pediatr Cardiol. 1993;14(3):159–161.
   PubMed Web of Science ®Google Scholar
• Chaoui R, Thiel G, Heling KS. OC29.02: Prevalence of an aberrant right subclavian artery (ARSA) in normal fetuses: a new soft marker for trisomy 21 risk assessment. Ultrasound Obstet Gynecol. 2005;26(4):356.
   Google Scholar
• Borenstein M, Cavoretto P, Allan L, Huggon I, Nicolaides KH. Aberrant right subclavian artery at 11+0 to 13+6 weeks of gestation in chromosomally normal and abnormal fetuses. Ultrasound Obstet Gynecol. 2008;31(1):20–24.
   PubMed Web of Science ®Google Scholar
• Paladini D, Sglavo G, Pastore G, Masucci A, D’Armiento MR, Nappi C. Aberrant right subclavian artery: incidence and correlation with other markers of Down sydrome in second trimester fetuses. Ultrasound Obstet Gynecol. 2012;39(2):191–195.
   PubMed Web of Science ®Google Scholar
• Ebbing C, Rasmussen S, Godfrey KM, Hanson MA, Kiserud T. Hepatic artery hemodynamics suggest operation of a buffer response in the human fetus. Reprod Sci. 2008;15(2):166–178.
   Web of Science ®Google Scholar
• Gouysse G, Couvelard A, Frachon S, et al. Relationship between vascular development and vascular differentiation during liver organogenesis in humans. J Hepatol. 2002;37(6):730–740.
   Web of Science ®Google Scholar
• Ebbing C, Rasmussen S, Godfrey KM, Hanson MA, Kiserud T. Hepatic artery hemodynamics suggest operation of a buffer response in the human fetus. Reprod Sci. 2008;15(2):166–178.
   Web of Science ®Google Scholar
• Kilavuz O, Vetter K. Is the liver of the fetus the 4th preferential for arterial blood supply besides brain, heart, and adrenal glands? J Perinat Med. 1999;27(2):103–106.
   Web of Science ®Google Scholar
• Zvanca M, Gielchinsky Yuval, Abdeljawad F, Bilardo CM, Nicolaides KH. Hepatic artery Doppler in trisomy 21 and euploid fetuses at 11–13 weeks. Prenat Diagn. 2011;31(1):22–27.
   Web of Science ®Google Scholar
• Iams JD, Goldenberg RL, Meis PJ, et al. The length of the cervix and the risk of spontaneous premature delivery. National Institute of Child Health and Human Development Maternal Fetal Medicine Unit Network. N Engl J Med. 1996;334(9):567–572.
   PubMed Web of Science ®Google Scholar
• Fonseca EB, Celik E, Parra M, Singh M, Nicolaides KH, Fetal Medicine Foundation Second Trimester Screening Group. Progesterone and the risk of preterm birth among women with a short cervix. N Engl J Med. 2007;357(5):462–469.
   PubMed Web of Science ®Google Scholar
• Mella MT, Berghella V. Prediction of preterm birth: cervical sonography. Semin Perinatol. 2009;33(5):317–324.
   PubMed Web of Science ®Google Scholar
• Greco E, Lange A, Ushakov F, Calvo JR, Nicolaides KH. Prediction of spontaneous preterm delivery from endocervical length at 11 to 13 weeks. Prenat Diagn. 2011;31(1):84–89.
   PubMed Web of Science ®Google Scholar
• Souka AP, Papastefanou I, Michalitsi V, Papadopoulos GK, Kassanos D. A predictive model of short cervix at 20–24 weeks using first-trimester cervical length measurement and maternal history. Prenat Diagn. 2011;31(2):202–206.
   Web of Science ®Google Scholar
• Greco E, Gupta R, Syngelaki A, Poon LC, Nicolaides KH. First-Trimester Screening for Spontaneous Preterm Delivery with Maternal Characteristics and Cervical Length. Fetal Diagn Ther. 2012; 31(3):154–161.
   PubMed Web of Science ®Google Scholar
• Salomon LJ, Alfirevic Z, Bilardo CM, et al. ISUOG Practice Guidelines: performance of first-trimester fetal ultrasound scan. Ultrasound Obstet Gynecol. 2013;41(1):102–113.
   PubMed Web of Science ®Google Scholar
• Benn P, Cuckle H, Pergament E. Non-invasive prenatal testing for aneuploidy: current status and future prospects. Ultrasound Obstet Gynecol. 2013;42(1):15–33.
   PubMed Web of Science ®Google Scholar