Potential clinical applications of adult human mesenchymal stem cell (Prochymal®) therapy

References

• FriedensteinAJChailakhyanRKLatsinikNVPanasyukAFKeiliss-BorokIVStromal cells responsible for transferring the microenvironment of the hemopoietic tissues. Cloning in vitro and retransplantation in vivoTransplantation19741743313404150881
   PubMed Web of Science ®Google Scholar
• Davis-SproulJMHarrisMPDavidsonNEKobrinBJJaffeeEMEmensLACost-effective manufacture of an allogeneic GM-CSF-secreting breast tumor vaccine in an academic cGMP facilityCytotherapy200571465616040383
   PubMed Web of Science ®Google Scholar
• BordignonCCarlo-StellaCColomboMPCell therapy: achievements and perspectivesHaematologica199984121110114910586214
   PubMed Web of Science ®Google Scholar
• MorrisonSJShahNMAndersonDJRegulatory mechanisms in stem cell biologyCell19978832872989039255
   PubMed Web of Science ®Google Scholar
• AugelloADe BariCThe regulation of differentiation in mesenchymal stem cellsHum Gene Ther201021101226123820804388
   PubMed Web of Science ®Google Scholar
• PittengerMFMackayAMBeckSCMultilineage potential of adult human mesenchymal stem cellsScience1999284541114314710102814
   PubMed Web of Science ®Google Scholar
• WilliamsJTSoutherlandSSSouzaJCalcuttAFCartledgeRGCells isolated from adult human skeletal muscle capable of differentiating into multiple mesodermal phenotypesAm Surg199965122269915526
   PubMed Web of Science ®Google Scholar
• HansonSEKimJJohnsonBHCharacterization of mesenchymal stem cells from human vocal fold fibroblastsLaryngoscope2010120354655120131365
   PubMed Web of Science ®Google Scholar
• JazedjeTPerinPMCzeresniaCEHuman fallopian tube: a new source of multipotent adult mesenchymal stem cells discarded in surgical proceduresJ Transl Med200974619538712
   PubMed Web of Science ®Google Scholar
• HuangTFChenYTYangTHIsolation and characterization of mesenchymal stromal cells from human anterior cruciate ligamentCytotherapy200810880681419023768
   PubMed Web of Science ®Google Scholar
• D’AndreaFDe FrancescoFFerraroGALarge-scale production of human adipose tissue from stem cells: a new tool for regenerative medicine and tissue bankingTissue Eng Part C Methods200814323324218781836
   PubMed Web of Science ®Google Scholar
• SarugaserRLickorishDBakshDHosseiniMMDaviesJEHuman umbilical cord perivascular (HUCPV) cells: a source of mesenchymal progenitorsStem Cells200523222022915671145
   PubMed Web of Science ®Google Scholar
• HoogduijnMJCropMJPeetersAMHuman heart, spleen, and perirenal fat-derived mesenchymal stem cells have immunomodulatory capacitiesStem Cells Dev200716459760417784833
   PubMed Web of Science ®Google Scholar
• LinTMChangHWWangKHIsolation and identification of mesenchymal stem cells from human lipoma tissueBiochem Biophys Res Commun2007361488388917679141
   PubMed Web of Science ®Google Scholar
• MiaoZJinJChenLIsolation of mesenchymal stem cells from human placenta: comparison with human bone marrow mesenchymal stem cellsCell Biol Int200630968168716870478
   PubMed Web of Science ®Google Scholar
• DickerALe BlancKAstromGFunctional studies of mesenchymal stem cells derived from adult human adipose tissueExp Cell Res2005308228329015925364
   PubMed Web of Science ®Google Scholar
• LeeOKKuoTKChenWMLeeKDHsiehSLChenTHIsolation of multipotent mesenchymal stem cells from umbilical cord bloodBlood200410351669167514576065
   PubMed Web of Science ®Google Scholar
• UccelliAMorettaLPistoiaVMesenchymal stem cells in health and diseaseNat Rev Immunol20088972673619172693
   PubMed Web of Science ®Google Scholar
• ChamberlainGFoxJAshtonBMiddletonJConcise review: mesenchymal stem cells: their phenotype, differentiation capacity, immunological features, and potential for homingStem Cells200725112739274917656645
   PubMed Web of Science ®Google Scholar
• DominiciMLe BlancKMuellerIMinimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statementCytotherapy20068431531716923606
   PubMed Web of Science ®Google Scholar
• YanezRLamanaMLGarcia-CastroJColmeneroIRamirezMBuerenJAAdipose tissue-derived mesenchymal stem cells have in vivo immunosuppressive properties applicable for the control of the graft-versus-host diseaseStem Cells200624112582259116873762
   PubMed Web of Science ®Google Scholar
• BruderSPJaiswalNHaynesworthSEGrowth kinetics, self-renewal, and the osteogenic potential of purified human mesenchymal stem cells during extensive subcultivation and following cryopreservationJ Cell Biochem19976422782949027588
   PubMed Web of Science ®Google Scholar
• LazarusHMHaynesworthSEGersonSLRosenthalNSCaplanAIEx vivo expansion and subsequent infusion of human bone marrow-derived stromal progenitor cells (mesenchymal progenitor cells): implications for therapeutic useBone Marrow Transplant19951645575648528172
   PubMed Web of Science ®Google Scholar
• MedawarPBThe homograft reactionProc R Soc Lond B Biol Sci195814993514516613614379
   PubMed Web of Science ®Google Scholar
• DickeKAvan der WaaijDvan BekkumDWThe use of stem-cell grafts in combined immune deficienciesBirth Defects Orig Artic Ser1975111391396238682
   PubMedGoogle Scholar
• GaspardoneADe FabritiisPScaffaRStem cell mobilization after coronary artery bypass graftingItal Heart J Suppl200451232815253141
   PubMedGoogle Scholar
• CoralliniFSecchieroPBeltramiAPTNF-alpha modulates the migratory response of mesenchymal stem cells to TRAILCell Mol Life Sci20106781307131420063037
   PubMed Web of Science ®Google Scholar
• DasRJahrHvan OschGJFarrellEThe role of hypoxia in bone marrow-derived mesenchymal stem cells: considerations for regenerative medicine approachesTissue Eng Part B Rev201016215916819698058
   PubMed Web of Science ®Google Scholar
• Mobius-WinklerSHilbergTMenzelKTime-dependent mobilization of circulating progenitor cells during strenuous exercise in healthy individualsJ Appl Physiol200910761943195019797690
   PubMed Web of Science ®Google Scholar
• PayneTROshimaHOkadaMA relationship between vascular endothelial growth factor, angiogenesis, and cardiac repair after muscle stem cell transplantation into ischemic heartsJ Am Coll Cardiol200750171677168417950150
   PubMed Web of Science ®Google Scholar
• LiHZuoSHeZParacrine factors released by GATA-4 overexpressed mesenchymal stem cells increase angiogenesis and cell survivalAm J Physiol Heart Circ Physiol2010299617721781
   Web of Science ®Google Scholar
• GnecchiMZhangZNiADzauVJParacrine mechanisms in adult stem cell signaling and therapyCirc Res2008103111204121919028920
   PubMed Web of Science ®Google Scholar
• GenoveseJASpadaccioCRivelloHGToyodaYPatelANElectrostimulated bone marrow human mesenchymal stem cells produce follistatinCytotherapy200911444845619530028
   PubMed Web of Science ®Google Scholar
• LiXLingWPennisiAHuman Placenta-Derived Adherent Cells Prevent Bone Loss, Stimulate Bone Formation, and Suppress Growth of Multiple Myeloma in BoneStem Cells201129226327321732484
   PubMed Web of Science ®Google Scholar
• LiLTianHYueWZhuFLiSLiWHuman mesenchymal stem cells play a dual role on tumor cell growth in vitro and in vitroJ Cell Physiol201122671860186721442622
   PubMed Web of Science ®Google Scholar
• RhodesLVMuirSEElliottSAdult human mesenchymal stem cells enhance breast tumorigenesis and promote hormone independenceBreast Cancer Res Treat2010121229330019597705
   PubMed Web of Science ®Google Scholar
• ZhuYSunZHanQHuman mesenchymal stem cells inhibit cancer cell proliferation by secreting DKK-1Leukemia200923592593319148141
   PubMed Web of Science ®Google Scholar
• KurandaKVargaftigJde la RocherePAge-related changes in human hematopoietic stem/progenitor cellsAging Cell201110354254621418508
   PubMed Web of Science ®Google Scholar
• DresslerMRButlerDLBoivinGPEffects of age on the repair ability of mesenchymal stem cells in rabbit tendonJ Orthop Res200523228729315734238
   PubMed Web of Science ®Google Scholar
• KatsaraOMahairaLGIliopoulouEGEffects of donor age, gender, and in vitro cellular aging on the phenotypic, functional, and molecular characteristics of mouse bone marrow-derived mesenchymal stem cellsStem Cells Dev20112091549156121204633
   PubMed Web of Science ®Google Scholar
• GarayoaMGarciaJLSantamariaCMesenchymal stem cells from multiple myeloma patients display distinct genomic profile as compared with those from normal donorsLeukemia20092381515152719357701
   PubMed Web of Science ®Google Scholar
• LiBFuJChenPZhuangWImpairment in immunomodulatory function of mesenchymal stem cells from multiple myeloma patientsArch Med Res201041862363321199732
   PubMed Web of Science ®Google Scholar
• WangXZhangZYaoCAngiogenic activity of mesenchymal stem cells in multiple myelomaCancer Invest2011291374121166497
   PubMed Web of Science ®Google Scholar
• NieYLauCLieAChanGMokMDefective phenotype of mesenchymal stem cells in patients with systemic lupus erythematosusLupus201019785085920511276
   PubMed Web of Science ®Google Scholar
• HaynesworthSEBaberMACaplanAICytokine expression by human marrow-derived mesenchymal progenitor cells in vitro: effects of dexamethasone and IL-1 alphaJ Cell Physiol199616635855928600162
   PubMed Web of Science ®Google Scholar
• UeyamaHHoribeTHinotsuSChromosomal variability of human mesenchymal stem cells cultured under hypoxic conditionsJ Cell Mol Med2011 [Epub ahead of print.]
   Web of Science ®Google Scholar
• SundinMRingdenOSundbergBNavaSGotherstromCLe BlancKNo alloantibodies against mesenchymal stromal cells, but presence of anti-fetal calf serum antibodies, after transplantation in allogeneic hematopoietic stem cell recipientsHaematologica20079291208121517666368
   PubMed Web of Science ®Google Scholar
• SpeesJLGregoryCASinghHInternalized antigens must be removed to prepare hypoimmunogenic mesenchymal stem cells for cell and gene therapyMol Ther20049574775615120336
   PubMed Web of Science ®Google Scholar
• ChachquesJCHerrerosJTraininiJAutologous human serum for cell culture avoids the implantation of cardioverter-defibrillators in cellular cardiomyoplastyInt J Cardiol200495Suppl 1S29S3315336842
   PubMed Web of Science ®Google Scholar
• O’DonoghueKChanJde la FuenteJMicrochimerism in female bone marrow and bone decades after fetal mesenchymal stem-cell trafficking in pregnancyLancet2004364942917918215246731
   PubMed Web of Science ®Google Scholar
• WollertKCMeyerGPLotzJIntracoronary autologous bonemarrow cell transfer after myocardial infarction: the BOOST randomised controlled clinical trialLancet2004364942914114815246726
   PubMed Web of Science ®Google Scholar
• AmadoLCSaliarisAPSchuleriKHCardiac repair with intramyocardial injection of allogeneic mesenchymal stem cells after myocardial infarctionProc Natl Acad Sci U S A200510232114741147916061805
   PubMed Web of Science ®Google Scholar
• PohKKSperryEYoungRGFreymanTBarringhausKGThompsonCARepeated direct endomyocardial transplantation of allogeneic mesenchymal stem cells: safety of a high dose, “off-the-shelf”, cellular cardiomyoplasty strategyInt J Cardiol2007117336036416889857
   PubMed Web of Science ®Google Scholar
• WolfDReinhardASeckingerAKatusHAKuechererHHansenADose-dependent effects of intravenous allogeneic mesenchymal stem cells in the infarcted porcine heartStem Cells Dev200918232132918435573
   PubMed Web of Science ®Google Scholar
• KraitchmanDLTatsumiMGilsonWDDynamic imaging of allogeneic mesenchymal stem cells trafficking to myocardial infarctionCirculation2005112101451146116129797
   PubMed Web of Science ®Google Scholar
• QuevedoHCHatzistergosKEOskoueiBNAllogeneic mesenchymal stem cells restore cardiac function in chronic ischemic cardiomyopathy via trilineage differentiating capacityProc Natl Acad Sci U S A200910633140221402719666564
   PubMed Web of Science ®Google Scholar
• PonceletAJHielALVercruysseJHermansDZechFGianelloPIntracardiac allogeneic mesenchymal stem cell transplantation elicits neo-angiogenesis in a fully immunocompetent ischaemic swine modelEur J Cardiothorac Surg201038678178720434353
   PubMed Web of Science ®Google Scholar
• PatelANSpadaccioCKuzmanMImproved cell survival in infarcted myocardium using a novel combination transmyocardial laser and cell delivery systemCell Transplant200716989990518293888
   PubMed Web of Science ®Google Scholar
• PrasadVKLucasKGKleinerGIEfficacy and safety of ex vivo cultured adult human mesenchymal stem cells (prochymal) in pediatric patients with severe refractory acute graft-versus-host disease in a compassionate use studyBiol Blood Marrow Transplant201117453454120457269
   PubMed Web of Science ®Google Scholar
• HareJMTraverseJHHenryTDA randomized, double-blind, placebo-controlled, dose-escalation study of intravenous adult human mesenchymal stem cells (prochymal) after acute myocardial infarctionJ Am Coll Cardiol200954242277228619958962
   PubMed Web of Science ®Google Scholar
• FrantzSBauersachsJErtlGPost-infarct remodelling: contribution of wound healing and inflammationCardiovasc Res200981347448118977766
   PubMed Web of Science ®Google Scholar
• JonesSHorwoodNCopeADazziFThe antiproliferative effect of mesenchymal stem cells is a fundamental property shared by all stromal cellsJ Immunol200717952824283117709496
   PubMed Web of Science ®Google Scholar
• TsuchidaHHashimotoJCrawfordEManskePLouJEngineered allogeneic mesenchymal stem cells repair femoral segmental defect in ratsJ Orthop Res2003211445312507579
   PubMed Web of Science ®Google Scholar
• ArinzehTLPeterSJArchambaultMPAllogeneic mesenchymal stem cells regenerate bone in a critical-sized canine segmental defectJ Bone Joint Surg Am200385-A101927193514563800
   PubMed Web of Science ®Google Scholar
• GuoSQXuJZZouQMJiangDMImmunological study of allogeneic mesenchymal stem cells during bone formationJ Int Med Res20093761750175920146873
   PubMed Web of Science ®Google Scholar
• BartholomewASturgeonCSiatskasMMesenchymal stem cells suppress lymphocyte proliferation in vitro and prolong skin graft survival in vivoExp Hematol2002301424811823036
   PubMed Web of Science ®Google Scholar
• Di NicolaMCarlo-StellaCMagniMHuman bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuliBlood200299103838384311986244
   PubMed Web of Science ®Google Scholar
• AggarwalSPittengerMFHuman mesenchymal stem cells modulate allogeneic immune cell responsesBlood200510541815182215494428
   PubMed Web of Science ®Google Scholar
• TolarJLe BlancKKeatingABlazarBRConcise review: hitting the right spot with mesenchymal stromal cellsStem Cells20102881446145520597105
   PubMed Web of Science ®Google Scholar
• SelmaniZNajiAZidiIHuman leukocyte antigen-G5 secretion by human mesenchymal stem cells is required to suppress T lymphocyte and natural killer function and to induce CD4+CD25highFOXP3+ regulatory T cellsStem Cells200826121222217932417
   PubMed Web of Science ®Google Scholar
• MeiselRZibertALaryeaMGobelUDaubenerWDillooDHuman bone marrow stromal cells inhibit allogeneic T-cell responses by indoleamine 2,3-dioxygenase-mediated tryptophan degradationBlood2004103124619462115001472
   PubMed Web of Science ®Google Scholar
• RenGZhangLZhaoXMesenchymal stem cell-mediated immunosuppression occurs via concerted action of chemokines and nitric oxideCell Stem Cell20082214115018371435
   PubMed Web of Science ®Google Scholar
• ChabannesDHillMMerieauEA role for heme oxygenase-1 in the immunosuppressive effect of adult rat and human mesenchymal stem cellsBlood2007110103691369417684157
   PubMed Web of Science ®Google Scholar
• MaitraBSzekelyEGjiniKHuman mesenchymal stem cells support unrelated donor hematopoietic stem cells and suppress T-cell activationBone Marrow Transplant200433659760414716336
   PubMed Web of Science ®Google Scholar
• Le BlancKRasmussonISundbergBTreatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cellsLancet200436394191439144115121408
   PubMed Web of Science ®Google Scholar
• RingdenOUzunelMRasmussonIMesenchymal stem cells for treatment of therapy-resistant graft-versus-host diseaseTransplantation200681101390139716732175
   PubMed Web of Science ®Google Scholar
• Le BlancKFrassoniFBallLMesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II studyLancet200837196241579158618468541
   PubMed Web of Science ®Google Scholar
• KebriaeiPIsolaLBahceciEAdult human mesenchymal stem cells added to corticosteroid therapy for the treatment of acute graft-versus-host diseaseBiol Blood Marrow Transplant200915780481119539211
   PubMed Web of Science ®Google Scholar
• NewmanREYooDLeRouxMADanilkovitch-MiagkovaATreatment of inflammatory diseases with mesenchymal stem cellsInflamm Allergy Drug Targets20098211012319530993
   PubMedGoogle Scholar
• KopenGCProckopDJPhinneyDGMarrow stromal cells migrate throughout forebrain and cerebellum, and they differentiate into astrocytes after injection into neonatal mouse brainsProc Natl Acad Sci U S A19999619107111071610485891
   PubMed Web of Science ®Google Scholar
• RafeiMBirmanEFornerKGalipeauJAllogeneic mesenchymal stem cells for treatment of experimental autoimmune encephalomyelitisMol Ther200917101799180319602999
   PubMed Web of Science ®Google Scholar
• ZhangJLiYLuMBone marrow stromal cells reduce axonal loss in experimental autoimmune encephalomyelitis miceJ Neurosci Res200684358759516773650
   PubMed Web of Science ®Google Scholar
• GerdoniEGalloBCasazzaSMesenchymal stem cells effectively modulate pathogenic immune response in experimental autoimmune encephalomyelitisAnn Neurol200761321922717387730
   PubMed Web of Science ®Google Scholar
• WakabayashiKNagaiASheikhAMTransplantation of human mesenchymal stem cells promotes functional improvement and increased expression of neurotrophic factors in a rat focal cerebral ischemia modelJ Neurosci Res20108851017102519885863
   PubMed Web of Science ®Google Scholar
• LiuNChenRDuHWangJZhangYWenJExpression of IL-10 and TNF-alpha in rats with cerebral infarction after transplantation with mesenchymal stem cellsCell Mol Immunol20096320721319567204
   PubMed Web of Science ®Google Scholar
• LiYChenJChenXGHuman marrow stromal cell therapy for stroke in rat: neurotrophins and functional recoveryNeurology200259451452312196642
   PubMed Web of Science ®Google Scholar
• WilkinsAKempKGintyMHaresKMallamEScoldingNHuman bone marrow-derived mesenchymal stem cells secrete brain-derived neurotrophic factor which promotes neuronal survival in vitroStem Cell Res200931637019411199
   PubMed Web of Science ®Google Scholar
• LiWYChoiYJLeePHMesenchymal stem cells for ischemic stroke: changes in effects after ex vivo culturingCell Transplant20081791045105919177841
   PubMed Web of Science ®Google Scholar
• ZappiaECasazzaSPedemonteEMesenchymal stem cells ameliorate experimental autoimmune encephalomyelitis inducing T-cell anergyBlood200510651755176115905186
   PubMed Web of Science ®Google Scholar
• ZhangJLiYChenJHuman bone marrow stromal cell treatment improves neurological functional recovery in EAE miceExp Neurol20051951162615904921
   PubMed Web of Science ®Google Scholar
• KassisIGrigoriadisNGowda-KurkalliBNeuroprotection and immunomodulation with mesenchymal stem cells in chronic experimental autoimmune encephalomyelitisArch Neurol200865675376118541795
   PubMedGoogle Scholar
• FreedmanMSBar-OrAAtkinsHLThe therapeutic potential of mesenchymal stem cell transplantation as a treatment for multiple sclerosis: consensus report of the International MSCT Study GroupMult Scler201016450351020086020
   PubMed Web of Science ®Google Scholar
• YamoutBHouraniRSaltiHBone marrow mesenchymal stem cell transplantation in patients with multiple sclerosis: a pilot studyJ Neuroimmunol20102271–218518920728948
   PubMed Web of Science ®Google Scholar
• KarussisDKarageorgiouCVaknin-DembinskyASafety and immunological effects of mesenchymal stem cell transplantation in patients with multiple sclerosis and amyotrophic lateral sclerosisArch Neurol201067101187119420937945
   PubMed Web of Science ®Google Scholar
• LeeJWFangXGuptaNSerikovVMatthayMAAllogeneic human mesenchymal stem cells for treatment of E. coli endotoxin-induced acute lung injury in the ex vivo perfused human lungProc Natl Acad Sci U S A200910638163571636219721001
   PubMed Web of Science ®Google Scholar
• GroveDAXuJJoodiRAttenuation of early airway obstruction by mesenchymal stem cells in a murine model of heterotopic tracheal transplantationJ Heart Lung Transplant201130334135021093298
   PubMed Web of Science ®Google Scholar
• KavanaghHMahonBPAllogeneic mesenchymal stem cells prevent allergic airway inflammation by inducing murine regulatory T cellsAllergy201166452353121091718
   PubMed Web of Science ®Google Scholar
• BonfieldTLKolozeMLennonDPZuchowskiBYangSECaplanAIHuman mesenchymal stem cells suppress chronic airway inflammation in the murine ovalbumin asthma modelAm J Physiol Lung Cell Mol Physiol20102996L760L77020817776
   PubMed Web of Science ®Google Scholar
• AbdiRFiorinaPAdraCNAtkinsonMSayeghMHImmunomodulation by mesenchymal stem cells: a potential therapeutic strategy for type 1 diabetesDiabetes20085771759176718586907
   PubMed Web of Science ®Google Scholar
• FotinoCRicordiCLauriolaVAlejandroRPileggiABone marrow-derived stem cell transplantation for the treatment of insulin-dependent diabetesRev Diabet Stud20107214415721060973
   PubMedGoogle Scholar
• InverardiLRicordiCTolerance and pancreatic islet transplantationPhilos Trans R Soc Lond B Biol Sci2001356140975976511375078
   PubMed Web of Science ®Google Scholar
• BermanDMWillmanMAHanDMesenchymal stem cells enhance allogeneic islet engraftment in nonhuman primatesDiabetes201059102558256820622174
   PubMed Web of Science ®Google Scholar
• UrbanVSKissJKovacsJMesenchymal stem cells cooperate with bone marrow cells in therapy of diabetesStem Cells200826124425317932424
   PubMed Web of Science ®Google Scholar
• XieQPHuangHXuBHuman bone marrow mesenchymal stem cells differentiate into insulin-producing cells upon microenvironmental manipulation in vitroDifferentiation200977548349119505629
   PubMed Web of Science ®Google Scholar
• SunYChenLHouXGDifferentiation of bone marrow-derived mesenchymal stem cells from diabetic patients into insulin-producing cells in vitroChin Med J (Engl)2007120977177617531117
   PubMed Web of Science ®Google Scholar
• TangDQCaoLZBurkhardtBRIn vivo and in vitro characterization of insulin-producing cells obtained from murine bone marrowDiabetes20045371721173215220196
   PubMed Web of Science ®Google Scholar
• ChenLBJiangXBYangLDifferentiation of rat marrow mesenchymal stem cells into pancreatic islet beta-cellsWorld J Gastroenterol200410203016302015378785
   PubMed Web of Science ®Google Scholar
• VolarevicVArsenijevicNLukicMLStojkovicMConcise review: Mesenchymal stem cell treatment of the complications of diabetes mellitusStem Cells201129151021280154
   PubMed Web of Science ®Google Scholar
• ZhangNLiJLuoRJiangJWangJABone marrow mesenchymal stem cells induce angiogenesis and attenuate the remodeling of diabetic cardiomyopathyExp Clin Endocrinol Diabetes2008116210411118286426
   PubMed Web of Science ®Google Scholar
• ComerotaAJLinkADouvilleJBurchardtERUpper extremity ischemia treated with tissue repair cells from adult bone marrowJ Vasc Surg201052372372920576396
   PubMed Web of Science ®Google Scholar
• FazanRJrBallejoGSalgadoMCMoraesMFSalgadoHCHeart rate variability and baroreceptor function in chronic diabetic ratsHypertension1997303 Pt 26326359322994
   PubMed Web of Science ®Google Scholar
• StroedterDSchmidtTBretzelRGFederlinKGlucose metabolism and left ventricular dysfunction are normalized by insulin and islet transplantation in mild diabetes in the ratActa Diabetol19953242352438750762
   PubMed Web of Science ®Google Scholar
• Abdel AzizMTEl-AsmarMFHaidaraMEffect of bone marrow-derived mesenchymal stem cells on cardiovascular complications in diabetic ratsMed Sci Monit20081411BR249BR25518971868
   PubMed Web of Science ®Google Scholar
• EzquerFEEzquerMEParrauDBCarpioDYanezAJCongetPASystemic administration of multipotent mesenchymal stromal cells reverts hyperglycemia and prevents nephropathy in type 1 diabetic miceBiol Blood Marrow Transplant200814663164018489988
   PubMed Web of Science ®Google Scholar
• LeeRHSeoMJRegerRLMultipotent stromal cells from human marrow home to and promote repair of pancreatic islets and renal glomeruli in diabetic NOD/scid miceProc Natl Acad Sci U S A200610346174381744317088535
   PubMed Web of Science ®Google Scholar
• HerreraMBBussolatiBBrunoSFonsatoVRomanazziGMCamussiGMesenchymal stem cells contribute to the renal repair of acute tubular epithelial injuryInt J Mol Med20041461035104115547670
   PubMed Web of Science ®Google Scholar
• KimHParkJSChoiYJBone marrow mononuclear cells have neurovascular tropism and improve diabetic neuropathyStem Cells20092771686169619544451
   PubMed Web of Science ®Google Scholar
• KwonDSGaoXLiuYBTreatment with bone marrow-derived stromal cells accelerates wound healing in diabetic ratsInt Wound J20085345346318593394
   PubMed Web of Science ®Google Scholar