Hydroxychloroquine and risk of development of cancers: a nationwide population-based cohort study

I-Chieh Mao1 Division of Critical Care, Departmen of Internal Medicine, Changhua Christian Hospital, Changhua, Taiwan

Ching-Yeh Lin2 Division of Hematology and Oncology, Department of Internal Medicine, Changhua Christian Hospital, Changhua, Taiwan

Chia-Lin Wu3 Division of Nephrology, Department of Internal Medicine, Changhua Christian Hospital, Changhua, Taiwan, [email protected];4 Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan

Chew-Teng Kor5 Internal Medicine Research Center, Changhua Christian Hospital, Changhua, Taiwan, [email protected];6 Graduate Institute of Statistics and Information Science, National Changhua University of Education, Changhua, Taiwan, [email protected]Correspondence[email protected]

Chia-Chu Chang3 Division of Nephrology, Department of Internal Medicine, Changhua Christian Hospital, Changhua, Taiwan, [email protected];7 Department of Internal Medicine, Kuang Tien General Hospital, Taichung, Taiwan, [email protected];8 School of Medicine, Chung-Shan Medical University, Taichung, Taiwan, [email protected];9 Department of Nutrition, Hungkuang University, Taichung, Taiwan, [email protected]Correspondence[email protected]

Pages 1435-1443 | Published online: 20 Aug 2018

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References

VerbaanderdCMaesHSchaafMBRepurposing drugs in oncology (ReDO) – chloroquine and hydroxychloroquine as anti-cancer agentsEcancermedicalscience201711135
Web of Science ®Google Scholar
CookKLWärriASoto-PantojaDRHydroxychloroquine inhibits autophagy to potentiate antiestrogen responsiveness in ER+ breast cancerClin Cancer Res201420123222323224928945
PubMed Web of Science ®Google Scholar
LinYCLinJFWenSIChloroquine and hydroxychloroquine inhibit bladder cancer cell growth by targeting basal autophagy and enhancing apoptosisKaohsiung J Med Sci201733521522328433067
PubMed Web of Science ®Google Scholar
ManicGObristFKroemerGVitaleIGalluzziLChloroquine and hydroxychloroquine for cancer therapyMol Cell Oncol201411e2991127308318
PubMedGoogle Scholar
AmaravadiRKLippincott-SchwartzJYinXMPrinciples and current strategies for targeting autophagy for cancer treatmentClin Cancer Res201117465466621325294
PubMed Web of Science ®Google Scholar
YangZJCheeCEHuangSSinicropeFAThe role of autophagy in cancer: therapeutic implicationsMol Cancer Ther20111091533154121878654
PubMed Web of Science ®Google Scholar
WhiteEThe role for autophagy in cancerJ Clin Invest20151251424625654549
PubMed Web of Science ®Google Scholar
TowersCGThorburnATherapeutic targeting of autophagyEBioMedicine201614152328029600
PubMed Web of Science ®Google Scholar
DereticVSaitohTAkiraSAutophagy in infection, inflammation and immunityNat Rev Immunol20171310722737
Web of Science ®Google Scholar
NixonRAThe role of autophagy in neurodegenerative diseaseNat Med201319898399723921753
PubMed Web of Science ®Google Scholar
MathewRKarantza-WadsworthVWhiteERole of autophagy in cancerNat Rev Cancer200771296196717972889
PubMed Web of Science ®Google Scholar
WhiteEDipaolaRSThe double-edged sword of autophagy modulation in cancerClin Cancer Res200915175308531619706824
PubMed Web of Science ®Google Scholar
RabinowitzJDWhiteEAutophagy and metabolismScience201033060091344134821127245
PubMed Web of Science ®Google Scholar
GiatEEhrenfeldMShoenfeldYCancer and autoimmune diseasesAutoimmun Rev201716101049105728778707
PubMed Web of Science ®Google Scholar
Bureau of National Health InsuranceNational Health Insurance Annual Statistical Report, 2016–2017 (bilingual). Available from: https://www.nhi.gov.tw/Resource/webdata/13767_1_National%20Health%20Insurance%20in%20Taiwan%202016-2017(bilingual).pdf
Google Scholar
CharlsonMEPompeiPAlesKLMackenzieCRA new method of classifying prognostic comorbidity in longitudinal studies: development and validationJ Chronic Dis19874053733833558716
PubMedGoogle Scholar
MellesRBMarmorMFThe risk of toxic retinopathy in patients on long-term hydroxychloroquine therapyJAMA Ophthalmol2014132121453146025275721
PubMed Web of Science ®Google Scholar
ShiTTYuXXYanLJXiaoHTResearch progress of hydroxychloroquine and autophagy inhibitors on cancerCancer Chemother Pharmacol201779228729427889812
PubMed Web of Science ®Google Scholar
FangYChenYChungTHydroxychloroquine and risk of cancer in patients with primary Sjögren syndrome: propensity score matched landmark analysisOncotarget2017846804618047129113317
PubMedGoogle Scholar
MathewRKarpCMBeaudoinBAutophagy suppresses tumorigenesis through elimination of p62Cell200913761062107519524509
PubMed Web of Science ®Google Scholar
KomatsuMWaguriSKoikeMHomeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient miceCell200713161149116318083104
PubMed Web of Science ®Google Scholar
KomatsuMWaguriSUenoTImpairment of starvation-induced and constitutive autophagy in Atg7-deficient miceJ Cell Biol2005169342543415866887
PubMed Web of Science ®Google Scholar
WhiteEDeconvoluting the context-dependent role for autophagy in cancerNat Rev Cancer201212640141022534666
PubMed Web of Science ®Google Scholar
K-HYKuoC-FHuangLHHuangW-KSeeL-CCancer risk in patients with inflammatory systemic autoimmune rheumatic diseasesMedicine20169518e354027149461
PubMed Web of Science ®Google Scholar
GoldbergSBSupkoJGNealJWA phase I study of erlotinib and hydroxychloroquine in advanced non-small-cell lung cancerJ Thorac Oncol20127101602160822878749
PubMed Web of Science ®Google Scholar

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