Profile of ciclesonide for the maintenance treatment of asthma

References

• US Department of Health and Human Services; National Institutes of Health (NIH); National Heart, Lung, and Blood InstituteExpert Panel Report 3: Guidelines for the Diagnosis and Management of Asthma NIH Publication No. 07-4051Bethesda, MDNational Institutes of Health2007
   Google Scholar
• Global Initiative for Asthma (GINA)Global Strategy for Asthma Management and PreventionGINA2010 Available from: http://www.ginasthma.org/pdf/GINA_Report_2010.pdfAccessed July 11, 2011
   Google Scholar
• Sunovian Pharmaceuticals IncAlvesco^® (ciclesonide) prescribing informationMarlborough, MASunovian Pharmaceuticals Inc2008
   Google Scholar
• NaveRClinical pharmacokinetic and pharmacodynamic profile of inhaled ciclesonideClin Pharmacokinet200948424325219492869
   PubMed Web of Science ®Google Scholar
• WinklerJHochhausGDerendorfHHow the lung handles drugs: pharmacokinetics and pharmacodynamics of inhaled corticosteroidsProc Am Thorac Soc20041435636316113458
   PubMedGoogle Scholar
• NewmanSSalmonANaveRDrollmannAHigh lung deposition of 99mTc-labeled ciclesonide administered via HFA-MDI to patients with asthmaRespir Med2006100337538416275052
   PubMed Web of Science ®Google Scholar
• LeachCLBethkeTDBoudreauRJTwo-dimensional and three-dimensional imaging show ciclesonide has high lung deposition and peripheral distribution: a nonrandomized study in healthy volunteersJ Aerosol Med200619211712616796536
   PubMedGoogle Scholar
• NaveRBethkeTDvan MarleSPZechKPharmacokinetics of [14C] ciclesonide after oral and intravenous administration to healthy subjectsClin Pharmacokinet200443747948615139796
   PubMed Web of Science ®Google Scholar
• BoeroSSabatiniFSilvestriMModulation of human lung fibroblast functions by ciclesonide: evidence for its conversion into the active metabolite desisobutyryl-ciclesonideImmunol Lett20071121394617707916
   PubMed Web of Science ®Google Scholar
• SilvestriMSerperoLPetecchiaLSabatiniFCerasoliFJrRossiGACytokine-activated bronchial epithelial cell pro-inflammatory functions are effectively downregulated in vitro by ciclesonidePulm Pharmacol Ther200619321021716084120
   PubMed Web of Science ®Google Scholar
• StoeckMRiedelRHochhausGIn vitro and in vivo anti-inflammatory activity of the new glucocorticoid ciclesonideJ Pharmacol Exp Ther2004309124925814718604
   PubMed Web of Science ®Google Scholar
• ErinEMZacharasiewiczASNicholsonGCRapid effect of inhaled ciclesonide in asthma: a randomized, placebo-controlled studyChest2008134474074518403668
   PubMed Web of Science ®Google Scholar
• HeijinkIHKauffmanHFVellengaEVeltman-StarkenburgCAPostmaDSde MonchyJGEffect of ciclesonide treatment on allergen-induced changes in T cell regulation in asthmaInt Arch Allergy Immunol2008145211112117848804
   PubMed Web of Science ®Google Scholar
• KawayamaTO’ByrnePMWatsonRMEffects of inhaled ciclesonide on circulating T-helper type 1/T-helper type 2 cells in atopic asthmatics after allergen challengeClin Exp Allergy200636111417142417083352
   PubMed Web of Science ®Google Scholar
• GauvreauGMBouletLPPostmaDSEffect of low-dose ciclesonide on allergen-induced responses in subjects with mild allergic asthmaJ Allergy Clin Immunol2005116228529116083781
   PubMed Web of Science ®Google Scholar
• TaylorDAJensenMWKanabarVA dose-dependent effect of the novel inhaled corticosteroid ciclesonide on airway responsiveness to adenosine-5′-monophosphate in asthmatic patientsAm J Respir Crit Care Med1999160123724310390406
   PubMed Web of Science ®Google Scholar
• KanniessFRichterKBohmeSJorresRAMagnussenHEffect of inhaled ciclesonide on airway responsiveness to inhaled AMP, the composition of induced sputum and exhaled nitric oxide in patients with mild asthmaPulm Pharmacol Ther200114214114711273796
   PubMed Web of Science ®Google Scholar
• WilsonAMDuongMPrattBDolovichMO’ByrnePMAnti-inflammatory effects of once daily low dose inhaled ciclesonide in mild to moderate asthmatic patientsAllergy200661553754216629781
   PubMed Web of Science ®Google Scholar
• ZietkowskiZBodzenta-LukaszykATomasiakMMSzymanskiWSkiepkoREffect of ciclesonide and fluticasone on exhaled nitric oxide in patients with mild allergic asthmaRespir Med200610091651165616443353
   PubMed Web of Science ®Google Scholar
• ManningPGibsonPGLassersonTJCiclesonide versus placebo for chronic asthma in adults and childrenCochrane Database Syst Rev20082CD00621718425941
   PubMed Web of Science ®Google Scholar
• ChapmanKRPatelPD’UrzoADMaintenance of asthma control by once-daily inhaled ciclesonide in adults with persistent asthmaAllergy200560333033715679718
   PubMed Web of Science ®Google Scholar
• AdachiMIshiharaKInoueHEfficacy and safety of once-daily inhaled ciclesonide in adults with mild to moderate asthma: a double-blind, placebo-controlled studyRespirology200712456657217587424
   PubMed Web of Science ®Google Scholar
• LangdonCGAdlerMMehraSAlexanderMDrollmannAOnce-daily ciclesonide 80 or 320 microg for 12 weeks is safe and effective in patients with persistent asthmaRespir Med2005991012751285
   Google Scholar
• PearlmanDSBergerWEKerwinELaforceCKunduSBanerjiDOnce-daily ciclesonide improves lung function and is well tolerated by patients with mild-to-moderate persistent asthmaJ Allergy Clin Immunol2005116612061212
   Google Scholar
• BergerWEKerwinEBernsteinDIPedinoffABenschGKarafilidisJEfficacy and safety evaluation of ciclesonide in subjects with mild-to-moderate asthma not currently using inhaled corticosteroidsAllergy Asthma Proc200930330431419549432
   PubMed Web of Science ®Google Scholar
• BatemanEKarpelJCasaleTWenzelSBanerjiDCiclesonide reduces the need for oral steroid use in adult patients with severe, persistent asthmaChest200612951176118716685007
   PubMed Web of Science ®Google Scholar
• ManningPGibsonPGLassersonTJCiclesonide versus other inhaled steroids for chronic asthma in children and adultsCochrane Database Syst Rev20082CD00703118425977
   PubMed Web of Science ®Google Scholar
• BuhlRVinklerIMagyarPComparable efficacy of ciclesonide once daily versus fluticasone propionate twice daily in asthmaPulm Pharmacol Ther200619640441216310388
   PubMed Web of Science ®Google Scholar
• MagnussenHHofmanJStanetaPLawoJPHellwigMEngelstatterRSimilar efficacy of ciclesonide once daily versus fluticasone propionate twice daily in patients with persistent asthmaJ Asthma200744755556317885859
   PubMed Web of Science ®Google Scholar
• BouletLPBatemanEDVovesRMullerTWolfSEngelstatterRA randomized study comparing ciclesonide and fluticasone propionate in patients with moderate persistent asthmaRespir Med200710181677168617448650
   PubMed Web of Science ®Google Scholar
• BatemanEDLinnhofAEHomikLFreudensprungUSmauLEngelstatterRComparison of twice-daily inhaled ciclesonide and fluticasone propionate in patients with moderate-to-severe persistent asthmaPulm Pharmacol Ther200821226427517604664
   PubMed Web of Science ®Google Scholar
• NiphadkarPJagannathKJoshiJMComparison of the efficacy of ciclesonide 160 microg QD and budesonide 200 microg BID in adults with persistent asthma: a phase III, randomized, double-dummy, open-label studyClin Ther200527111752176316368446
   PubMed Web of Science ®Google Scholar
• HanselTTBenezetOKafeHA multinational, 12-week, randomized study comparing the efficacy and tolerability of ciclesonide and budesonide in patients with asthmaClin Ther200628690692016860173
   PubMed Web of Science ®Google Scholar
• BouletLPDrollmannAMagyarPComparative efficacy of once-daily ciclesonide and budesonide in the treatment of persistent asthmaRespir Med2006100578579416427266
   PubMed Web of Science ®Google Scholar
• UkenaDBibergerCSteinijansVCiclesonide is more effective than budesonide in the treatment of persistent asthmaPulm Pharmacol Ther200720556257016962345
   PubMed Web of Science ®Google Scholar
• VermeulenJHGyurkovitsKRauerHEngelstatterRRandomized comparison of the efficacy and safety of ciclesonide and budesonide in adolescents with severe asthmaRespir Med2007101102182219117614270
   PubMed Web of Science ®Google Scholar
• LipworthBJKalinerMALaForceCFEffect of ciclesonide and fluticasone on hypothalamic-pituitary-adrenal axis function in adults with mild-to-moderate persistent asthmaAnn Allergy Asthma Immunol200594446547215875528
   PubMed Web of Science ®Google Scholar
• DeromELouisRTieslerCEngelstatterRKaufmanJMJoosGFEffects of ciclesonide and fluticasone on cortisol secretion in patients with persistent asthmaEur Respir J20093361277128619164356
   PubMed Web of Science ®Google Scholar
• ChylackLTJrGrossGNPedinoffAA randomized, controlled trial to investigate the effect of ciclesonide and beclomethasone dipropionate on eye lens opacityJ Asthma2008451089390219085579
   PubMed Web of Science ®Google Scholar