References
- HauserWAAnnegersJFKurlandLTPrevalence of epilepsy in Rochester, Minnesota: 1940–1980Epilepsia19913244294451868801
- HauserWAAnnegersJFKurlandLTIncidence of epilepsy and unprovoked seizures in Rochester, Minnesota: 1935–1984Epilepsia19933434534688504780
- ForsgrenLBeghiEOunASillanpaaMThe epidemiology of epilepsy in Europe – a systematic reviewEur J Neurology200512245253
- BirbeckGLHaysRDCuiXPVickreyBGSeizure Reduction and Quality of Life Improvements in People with EpilepsyEpilepsia200243553553812027916
- WirrellECEpilepsy-related InjuriesEpilepsia200647Suppl 1798617044832
- JostyICNarayananVDicksonWABurns in patients with epilepsy: changes in epidemiology and implications for burn treatment and preventionEpilepsia200041445345610756412
- HamerHMSpottkeAAletseeCDirect and indirect costs of refractory epilepsy in a tertiary epilepsy center in GermanyEpilepsia200647122165217217201718
- KraussGLAmpawLKrumholzAIndividual state driving restrictions for people with epilepsy in the USNeurology200157101780178511723263
- KwanPBrodieMJEarly identification of refractory epilepsyN Engl J Med2000342531431910660394
- FaughtEMonotherapy in adults and elderly personsNeurology200769Suppl 3S3S918071156
- AlmeidaLFalcãoAMaiaJMazurDGellertMSoares-da-SilvaPSingle-dose and steady-state pharmacokinetics of eslicarbazepine acetate (BIA 2-093) in healthy elderly and young subjectsJ Clin Pharmacol2005451062106616100301
- AlmeidaLSoares-da-SilvaPEslicarbazepine acetate (BIA 2-093)Neurotherapeutics20074889617199020
- VolosovAXiaodongSPeruccaEYagenBSintovABialerMEnantioselective pharmacokinetics of 10-hydroxycarbazepine after oral administration of oxcarbazepine to health Chinese subjectsClin Pharmacol Ther199966654755310613609
- BenesJParadaAFigueiredoAAAnticonvulsant and sodium channel-blocking properties of novel 10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide derivativesJ Med Chem199942142582258710411478
- YamaokaKVogelSMSeyamaINa+ channel pharmacology and molecular mechanisms of gatingCurr Pharm Des200612442944216472137
- ParadaASoares-da-SilvaPThe novel anticonvulsant BIA 2-093 inhibits transmitter release during opening of voltage-gated sodium channels: a comparison with carbamazepine and oxcarbazepineNeurochem Int20024043544011821151
- BonifácioMJSheridanRDParadaACunhaRAPatmoreLSoares-da-SilvaPInteraction of the novel anticonvulsant, BIA 2-093, with voltage-gated sodium channels: comparison with carbamazepineEpilepsia200142560060811380566
- El-MallakhRSHuffMOMood stabilizers and ion regulationHarv Rev Psychiatry20019233211159930
- AraújoIMAmbrósioAFLealECNeurotoxicity induced by antiepileptic drugs in cultured hippocampal neurons: a comparative study between carbamazepine, oxcarbazepine, and two new putative antiepileptic drugs, BIA 2–024 and BIA 2-093Epilepsia200445121498150515571507
- Fontes-RibeiroCNunesTFalcäoAEslicarbazepine acetate (BIA 2-093): Relative bioavailability and bioequivalence of 50 mg/mL oral suspension and 200 mg and 800 mg tablet formulationsDrugs R D20056525326016128595
- MaiaJVas-da-SilvaMAlmeidaLEffect of food on the pharmacokinetic profile of eslicarbazepine acetate (BIA 2-093)Drugs R D20056420120615991880
- Fontes-RibeiroCMacedoTNunesTDosage form proportionality and food effect of the final tablet formulation of eslicarbazepine acetate: randomized, open-label, crossover, single-centre study in healthy volunteersDrugs R D20089644745418989993
- FalcãoAMaiaJAlmeidaLMazurDGellertMSoares-da-SilvaPEffect of gender on the pharmacokinetics of eslicarbazepine acetate (BIA 2-093), a new voltage-gated sodium channel blockerBiopharm Drug Dispos200728524925617443646
- AlmeidaLPotgieterJLMaiaJPotgieterMAMotaFSoares-da-SilvaPPharmacokinetics of eslicarbazepine acetate in patients with moderate hepatic impairmentEur J Clin Pharmacol200864326727318157705
- AlmeidaLSoares-da-SilvaPSafety, tolerability and pharmacolokinetic profile of BIA 2-093, a novel putative antiepileptic, in a rising multiple-dose study in young healthy humansJ Clin Pharmacol20044490691815286095
- MaiaJAlmeidaLFalcãoAEffect of renal impairment on the pharmacokinetics of eslicarbazepine acetateInt J Clin Pharmacol Ther200846311912018397682
- AlvesGFigueiredoICastel-BrancoMBiomed Chromatogr200721111127113417594694
- ElgerCHalászPMaiaJAlmeidaLSoares-da-SilvaPBIA-2093–301 Investigators Study GroupEfficacy and safety of eslicarbazepine acetate as adjunctive treatment in adults with refractory partial-onset seizures: A randomized, double blind, placebo-controlled, parallel-group phase III studyEpilepsia200950345446319243424
- European Medicines AgencyCHMP Assessment Report for Exalief: International Nonproprietary Name: eslicarbazepine acetateLondon1922009http://www.emea.europa.eu/humandocs/PDFs/EPAR/exalief/H-987-en6.pdf, accessed 13 October 2009.
- Vas da SilvaMCostaRSoaresEEffect of eslicarbazepine acetate on the pharmacokinetics of digoxin in healthy subjectsFundam Clin Pharmacol2009Epub ahead of print.
- RochaJFCaz-da-SilvaMAlmeidaLEffect of eslicarbazepine acetate on the pharmacokinetics of metformin in healthy subjectsInt J Clin Pharmacol Ther200947425526119356391
- Sierra-ParedesGOreiro-GarcíaTVázquez-IllanesMDSierra-MarcuňoGEffect of eslicarbazepine acetate (BIA 2–093) on latrunculin A-induced seizures and extracellular amino acid concentrations in the rat hippocampusEpilepsy Res2007771364217890056
- Sierra-ParedesGNúňez-RodriguezAVázquez-LópezAOreiro-GarcíaTSierra-MarcuňoGAnticonvulsant effect of eslicarbazepine acetate (BIA 2-093) on seizures induced by microperfusion of picrotoxin in the hippocampus of freely moving ratsEpilepsy Res2006722–314014616920333
- ElgerCBialerMCramerJAMaiaJAlmeidaLSoares-da-SilvaPEslicarbazepine acetate: A double-blind, add-on, placebo-controlled, exploratory trial in adult patients with partial-onset seizuresEpilepsia200748349750417319919
- AlmeidaLMinciuINunesTPharmacokinetics, efficacy, and tolerability of eslicarbazepine acetate in children and adolescents with epilepsyJ Clin Pharmacol200848896697718508949
- IsojarviJITurkkaJPakarinenAJKotilaMRattyaJMyllylaVVThyroid function in men taking carbamazepine, oxcarbazepine, or valproate for epilepsyEpilepsia200142793093411488894
- HirfanogluTSerdarogluACamurdanOThyroid function and volume in epileptic children using carbamazepine, oxcarbazepine and valproatePediatrics International200749682282618045279
- MintzerSBoppanaPToguriJDeSantisAVitamin D levels and bone turnover in epilepsy patients taking carbamazepine or oxcarbazepineEpilepsia200647351051516529614
- CansuAYesilkayaESerdaroğluAEvaluation of bone turnover in epileptic children using oxcarbazepinePediatr Neurol20083926627118805365
- DeckersCCzuczwarSHeksterYSelection of antiepileptic drug polytherapy based on mechanisms of action: the evidence reviewedEpilepsia200041111364137411077449
- LeppikIEMonotherapy and polypharmacyNeurology20005511 Suppl 3S25S2911147565