References
- SchlettCLMassaroJMLehmanSJNovel measurements of periaortic adipose tissue in comparison to anthropometric measures of obesity, and abdominal adipose tissueInt J Obes (Lond)200933222623219139753
- LehmanSJMassaroJMSchlettCLO’DonnellCJHoffmannUFoxCSPeriaortic fat, cardiovascular disease risk factors, and aortic calcification: the Framingham Heart StudyAtherosclerosis2010210265666120152980
- FitzgibbonsTPKoganSAouadiMHendricksGMStraubhaarJCzechMPSimilarity of mouse perivascular and brown adipose tissues and their resistance to diet-induced inflammationAm J Physiol Heart Circ Physiol20113014H1425H143721765057
- ChatterjeeTKStollLLDenningGMProinflammatory phenotype of perivascular adipocytes: influence of high-fat feedingCirc Res2009104454154919122178
- RittigKDoldererJHBalletshoferBThe secretion pattern of perivascular fat cells is different from that of subcutaneous and visceral fat cellsDiabetologia20125551514152522327346
- BellLNWardJLDegawa-YamauchiMAdipose tissue production of hepatocyte growth factor contributes to elevated serum HGF in obesityAm J Physiol Endocrinol Metab20062914E843E84816757549
- Gálvez-PrietoBBolbrinkerJStucchiPComparative expression analysis of the renin-angiotensin system components between white and brown perivascular adipose tissueJ Endocrinol20081971556418372232
- HansenJBKristiansenKRegulatory circuits controlling white versus brown adipocyte differentiationBiochem J2006398215316816898874
- TirabyCLanginDConversion from white to brown adipocytes: a strategy for the control of fat mass?Trends Endocrinol Metab2003141043944114643055
- BoströmPWuJJedrychowskiMPA PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesisNature2012481738246346822237023
- CaoLChoiEYLiuXWhite to brown fat phenotypic switch induced by genetic and environmental activation of a hypothalamic-adipocyte axisCell Metab201114332433821907139
- MarimanECWangPAdipocyte extracellular matrix composition, dynamics and role in obesityCell Mol Life Sci20106781277129220107860
- GiordanoASongCKBowersRRWhite adipose tissue lacks significant vagal innervation and immunohistochemical evidence of parasympathetic innervationAm J Physiol Regul Integr Comp Physiol20062915R1243R125516809481
- GuzikTJMarvarPJCzesnikiewicz-GuzikMKorbutRPerivascular adipose tissue as a messenger of the brain-vessel axis: role in vascular inflammation and dysfunctionJ Physiol Pharmacol200758459161018195475
- SchererPEWilliamsSFoglianoMBaldiniGLodishHFA novel serum protein similar to C1q, produced exclusively in adipocytesJ Biol Chem19952704526746267497592907
- AritaYKiharaSOuchiNParadoxical decrease of an adipose-specific protein, adiponectin, in obesityBiochem Biophys Res Commun19992571798310092513
- TurerATSchererPEAdiponectin: mechanistic insights and clinical implicationsDiabetologia20125592319232622688349
- LamKSXuAAdiponectin: protection of the endotheliumCurr Diab Rep20055425425916033674
- OhashiKOuchiNMatsuzawaYAdiponectin and hypertensionAm J Hypertens201124326326920930707
- OkamotoYAritaYNishidaMAn adipocyte-derived plasma protein, adiponectin, adheres to injured vascular wallsHorm Metab Res2000322475010741683
- TilgHMoschenARAdipocytokines: mediators linking adipose tissue, inflammation and immunityNat Rev Immunol200661077278316998510
- FésüsGDubrovskaGGorzelniakKAdiponectin is a novel humoral vasodilatorCardiovasc Res200775471972717617391
- ZhuWChengKKVanhouttePMLamKSXuAVascular effects of adiponectin: molecular mechanisms and potential therapeutic interventionClin Sci (Lond)2008114536137418230060
- MohammedMMMyersDSSofolaOAHainsworthRDrinkhillMJVasodilator effects of leptin on canine isolated mesenteric arteries and veinsClin Exp Pharmacol Physiol200734877177417600555
- NakagawaKHigashiYSasakiSOshimaTMatsuuraHChayamaKLeptin causes vasodilation in humansHypertens Res200225216116512047029
- SahinASBariskanerHThe mechanisms of vasorelaxant effect of leptin on isolated rabbit aortaFundam Clin Pharmacol200721659560018034660
- KimuraKTsudaKBabaAInvolvement of nitric oxide in endothelium-dependent arterial relaxation by leptinBiochem Biophys Res Commun2000273274574910873674
- RahmouniKHaynesWGEndothelial effects of leptin: implications in health and diseasesCurr Diab Rep20055426026616033675
- RodríguezAFortuñoAGómez-AmbrosiJZalbaGDiezJFrühbeckGThe inhibitory effect of leptin on angiotensin II-induced vasoconstriction in vascular smooth muscle cells is mediated via a nitric oxide-dependent mechanismEndocrinology2007148132433117038553
- KnudsonJDDincerUDZhangCLeptin receptors are expressed in coronary arteries, and hyperleptinemia causes significant coronary endothelial dysfunctionAm J Physiol Heart Circ Physiol20052891H48H5615749744
- ShekEWBrandsMWHallJEChronic leptin infusion increases arterial pressureHypertension1998311 Pt 24094149453337
- CaoRBrakenhielmEWahlestedtCThybergJCaoYLeptin induces vascular permeability and synergistically stimulates angiogenesis with FGF-2 and VEGFProc Natl Acad Sci U S A200198116390639511344271
- YamawakiHTsubakiNMukohdaMOkadaMHaraYOmentin, a novel adipokine, induces vasodilation in rat isolated blood vesselsBiochem Biophys Res Commun2010393466867220170632
- LeeYCChangHHChiangCLRole of perivascular adipose tissue-derived methyl palmitate in vascular tone regulation and pathogenesis of hypertensionCirculation2011124101160117121844078
- HenrichotEJuge-AubryCEPerninAProduction of chemokines by perivascular adipose tissue: a role in the pathogenesis of atherosclerosis?Arterioscler Thromb Vasc Biol200525122594259916195477
- GaoYJLuCSuLYSharmaAMLeeRMModulation of vascular function by perivascular adipose tissue: the role of endothelium and hydrogen peroxideBr J Pharmacol2007151332333117384669
- GaoYJTakemoriKSuLYPerivascular adipose tissue promotes vasoconstriction: the role of superoxide anionCardiovasc Res200671236337316756966
- LiYMiharaKSaifeddineMPerivascular adipose tissue-derived relaxing factors: release by peptide agonists via proteinase-activated receptor-2 (PAR2) and non-PAR2 mechanismsBr J Pharmacol201116481990200221615723
- KetonenJShiJMartonenEMervaalaEPeriadventitial adipose tissue promotes endothelial dysfunction via oxidative stress in diet-induced obese C57Bl/6 miceCirc J20107471479148720526041
- MarchesiCEbrahimianTAnguloOParadisPSchiffrinELEndothelial nitric oxide synthase uncoupling and perivascular adipose oxidative stress and inflammation contribute to vascular dysfunction in a rodent model of metabolic syndromeHypertension20095461384139219822799
- DashwoodMRDooleyAShi-WenXAbrahamDJSouzaDSDoes periadventitial fat-derived nitric oxide play a role in improved saphenous vein graft patency in patients undergoing coronary artery bypass surgery?J Vasc Res200744317518117308436
- Gil-OrtegaMStucchiPGuzmán-RuizRAdaptative nitric oxide overproduction in perivascular adipose tissue during early diet-induced obesityEndocrinology201015173299330620410199
- MalinowskiMDejaMAGolbaKSRolederTBiernatJWośSPerivascular tissue of internal thoracic artery releases potent nitric oxide and prostacyclin-independent anticontractile factorEur J Cardiothorac Surg200833222523118083040
- FangLZhaoJChenYHydrogen sulfide derived from periadventitial adipose tissue is a vasodilatorJ Hypertens200927112174218519644389
- KöhnCSchleifenbaumJSzijártóIADifferential effects of cystathionine-γ-lyase-dependent vasodilatory H2S in periadventitial vasoregulation of rat and mouse aortasPLoS One201278e4195122870268
- WójcickaGJamroz-WiśniewskaAAtanasovaPChaldakovGNChylińska-KulaBBeltowskiJDifferential effects of statins on endogenous H2S formation in perivascular adipose tissuePharmacol Res2010631687620969959
- LeeRMBaderMAleninaNSantosRAGaoYJLuCMas receptors in modulating relaxation induced by perivascular adipose tissueLife Sci20118913–1446747221820449
- SoltisEECassisLAInfluence of perivascular adipose tissue on rat aortic smooth muscle responsivenessClin Exp Hypertens A19911322772962065467
- DubrovskaGVerlohrenSLuftFCGollaschMMechanisms of ADRF release from rat aortic adventitial adipose tissueAm J Physiol Heart Circ Physiol20042863H1107H111314644761
- LöhnMDubrovskaGLauterbachBLuftFCGollaschMSharmaAMPeriadventitial fat releases a vascular relaxing factorFASEB J20021691057106312087067
- VerlohrenSDubrovskaGTsangSYVisceral periadventitial adipose tissue regulates arterial tone of mesenteric arteriesHypertension200444327127615302842
- GollaschMDubrovskaGParacrine role for periadventitial adipose tissue in the regulation of arterial toneTrends Pharmacol Sci2004251264765315530643
- ReifenbergerMSTurkJRNewcomerSCBoothFWLaughlinMHPerivascular fat alters reactivity of coronary artery: effects of diet and exerciseMed Sci Sports Exerc200739122125213418046183
- RittigKStaibKMachannJPerivascular fatty tissue at the brachial artery is linked to insulin resistance but not to local endothelial dysfunctionDiabetologia200851112093209918712517
- LuCZhaoAXGaoYJLeeRMModulation of vein function by perivascular adipose tissueEur J Pharmacol20116571–311111621236250
- LynchFMWithersSBYaoZPerivascular adipose tissue-derived adiponectin activates BKCa channels to induce anticontractile responsesAm J Physiol Heart Circ Physiol Epub January 4, 2013
- GaoYJZengZHTeohKPerivascular adipose tissue modulates vascular function in the human internal thoracic arteryJ Thorac Cardiovasc Surg200513041130113616214530
- WithersSBAgabiti-RoseiCLivingstoneDMMacrophage activation is responsible for loss of anticontractile function in inflamed perivascular fatArterioscler Thromb Vasc Biol201131490891321273560
- GreensteinASKhavandiKWithersSBLocal inflammation and hypoxia abolish the protective anticontractile properties of perivascular fat in obese patientsCirculation2009119121661167019289637
- LeeRMLuCSuLYGaoYJEndothelium-dependent relaxation factor released by perivascular adipose tissueJ Hypertens200927478279019516177
- Gálvez-PrietoBSomozaBGil-OrtegaMAnticontractile effect of perivascular adipose tissue and leptin are reduced in hypertensionFront Pharmacol2012310322679436
- LobatoNSNevesKBFilgueiraFPThe adipokine chemerin augments vascular reactivity to contractile stimuli via activation of the MEK-ERK1/2 pathwayLife Sci20129113–1460060622521290
- YamawakiHVascular effects of novel adipocytokines: focus on vascular contractility and inflammatory responsesBiol Pharm Bull201134330731021372376
- MaenhautNBoydensCVan de VoordeJHypoxia enhances the relaxing influence of perivascular adipose tissue in isolated mice aortaEur J Pharmacol20106412–320721220553914
- WangPXuTYGuanYFSuDFFanGRMiaoCYPerivascular adipose tissue-derived visfatin is a vascular smooth muscle cell growth factor: role of nicotinamide mononucleotideCardiovasc Res200981237038018952695
- LuCSuLYLeeRMGaoYJMechanisms for perivascular adipose tissue-mediated potentiation of vascular contraction to perivascular neuronal stimulation: the role of adipocyte-derived angiotensin IIEur J Pharmacol20106341–310711220156432
- PayneGABohlenHGDincerUDBorbouseLTuneJDPeriadventitial adipose tissue impairs coronary endothelial function via PKC-beta-dependent phosphorylation of nitric oxide synthaseAm J Physiol Heart Circ Physiol20092971H460H46519482966
- ShyuKGLienLMWangBWKuanPChangHResistin contributes to neointimal formation via oxidative stress after vascular injuryClin Sci (Lond)2011120312112920795947
- OdaATaniguchiTYokoyamaMLeptin stimulates rat aortic smooth muscle cell proliferation and migrationKobe J Med Sci200147314115011729375
- HuangFXiongXWangHYouSZengHLeptin-induced vascular smooth muscle cell proliferation via regulating cell cycle, activating ERK1/2 and NF-kappaBActa Biochim Biophys Sin (Shanghai)201042532533120458445
- BohlenFKratzschJMuellerMLeptin inhibits cell growth of human vascular smooth muscle cellsVascul Pharmacol2007461677116890497
- RuanCCZhuDLChenQZPerivascular adipose tissue-derived complement 3 is required for adventitial fibroblast functions and adventitial remodeling in deoxycorticosterone acetate-salt hypertensive ratsArterioscler Thromb Vasc Biol201030122568257420864665
- LamersDSchlichRGreulichSSassonSSellHEckelJOleic acid and adipokines synergize in inducing proliferation and inflammatory signaling in human vascular smooth muscle cellsJ Cell Mol Med20111551177118820518853
- WangYLamKSXuJYAdiponectin inhibits cell proliferation by interacting with several growth factors in an oligomerization-dependent mannerJ Biol Chem200528018183411834715734737
- MotobayashiYIzawa-IshizawaYIshizawaKAdiponectin inhibits insulin-like growth factor-1-induced cell migration by the suppression of extracellular signal-regulated kinase 1/2 activation, but not Akt in vascular smooth muscle cellsHypertens Res200932318819319262481
- BarandierCMontaniJPYangZMature adipocytes and perivascular adipose tissue stimulate vascular smooth muscle cell proliferation: effects of aging and obesityAm J Physiol Heart Circ Physiol20052895H1807H181316024563
- BrionesAMNguyen Dinh CatACalleraGEAdipocytes produce aldosterone through calcineurin-dependent signaling pathways: implications in diabetes mellitus-associated obesity and vascular dysfunctionHypertension20125951069107822493070
- Nguyen Dinh CatABrionesAMCalleraGEAdipocyte-derived factors regulate vascular smooth muscle cells through mineralocorticoid and glucocorticoid receptorsHypertension201158347948821788604
- MaLMaSHeHPerivascular fat-mediated vascular dysfunction and remodeling through the AMPK/m TOR pathway in high-fat diet-induced obese ratsHypertens Res201033544645320186150
- WeisbergSPMcCannDDesaiMRosenbaumMLeibelRLFerranteAWJrObesity is associated with macrophage accumulation in adipose tissueJ Clin Invest2003112121796180814679176
- XuHBarnesGTYangQChronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistanceJ Clin Invest2003112121821183014679177
- RebolledoARebolledoORMarraCAEarly alterations in vascular contractility associated to changes in fatty acid composition and oxidative stress markers in perivascular adipose tissueCardiovasc Diabetol2010916520964827
- HuangFLezamaMAOntiverosJAEffect of losartan on vascular function in fructose-fed rats: the role of perivascular adipose tissueClin Exp Hypertens20103229810420374189
- KosteliASugaruEHaemmerleGWeight loss and lipolysis promote a dynamic immune response in murine adipose tissueJ Clin Invest2010120103466347920877011
- FortuñoARodríguezAGómez-AmbrosiJLeptin inhibits angiotensin II-induced intracellular calcium increase and vasoconstriction in the rat aortaEndocrinology200214393555356012193570
- PayneGABorbouseLKumarSEpicardial perivascular adipose-derived leptin exacerbates coronary endothelial dysfunction in metabolic syndrome via a protein kinase C-beta pathwayArterioscler Thromb Vasc Biol20103091711171720576943
- MeijerRIBakkerWAltaCLPerivascular adipose tissue control of insulin-induced vasoreactivity in muscle is impaired in db/db miceDiabetes201362259059823048187
- LeeRMLuCSuLYWerstuckGGaoYJEffects of hyperglycemia on the modulation of vascular function by perivascular adipose tissueJ Hypertens200927111813119050452
- GálvezBde CastroJHeroldDPerivascular adipose tissue and mesenteric vascular function in spontaneously hypertensive ratsArterioscler Thromb Vasc Biol20062661297130216601235
- LeeRMDingLLuCSuLYGaoYJAlteration of perivascular adipose tissue function in angiotensin II-induced hypertensionCan J Physiol Pharmacol2009871194495319935902
- Gálvez-PrietoBDubrovskaGCanoMVA reduction in the amount and anti-contractile effect of periadventitial mesenteric adipose tissue precedes hypertension development in spontaneously hypertensive ratsHypertens Res20083171415142318957813
- ZengZHZhangZHLuoBHThe functional changes of the perivascular adipose tissue in spontaneously hypertensive rats and the effects of atorvastatin therapyClin Exp Hypertens200931435536319811363
- LiRAndersenIAlekeJGolubinskayaVGustafssonHNilssonHReduced anti-contractile effect of perivascular adipose tissue on mesenteric small arteries from spontaneously hypertensive rats: role of Kv7 channelsEur J Pharmacol20136981–331031523059186
- LuCSuLYLeeRMGaoYJAlterations in perivascular adipose tissue structure and function in hypertensionEur J Pharmacol20116561–3687321277297
- RodríguezAFrühbeckGGómez-AmbrosiJThe inhibitory effect of leptin on angiotensin II-induced vasoconstriction is blunted in spontaneously hypertensive ratsJ Hypertens20062481589159716877962
- VerhagenSNVisserenFLPerivascular adipose tissue as a cause of atherosclerosisAtherosclerosis2011214131020646709
- ThalmannSMeierCALocal adipose tissue depots as cardiovascular risk factorsCardiovasc Res200775469070117412312
- VelaDBujaLMMadjidMThe role of periadventitial fat in atherosclerosisArch Pathol Lab Med2007131348148717516753
- BakerARSilvaNFQuinnDWHuman epicardial adipose tissue expresses a pathogenic profile of adipocytokines in patients with cardiovascular diseaseCardiovasc Diabetol20065116412224
- ChengKHChuCSLeeKTAdipocytokines and proinflammatory mediators from abdominal and epicardial adipose tissue in patients with coronary artery diseaseInt J Obes (Lond)200832226827417878891
- EirasSTeijeira-FernándezEShamagianLGFernandezALVazquez-BoqueteAGonzalez-JuanateyJRExtension of coronary artery disease is associated with increased IL-6 and decreased adiponectin gene expression in epicardial adipose tissueCytokine200843217418018562207
- MazurekTZhangLZalewskiAHuman epicardial adipose tissue is a source of inflammatory mediatorsCirculation2003108202460246614581396
- SilaghiAAchardVPaulmyer-LacroixOExpression of adrenomedullin in human epicardial adipose tissue: role of coronary statusAm J Physiol Endocrinol Metab20072935E1443E145017878224
- IshikawaYAkasakaYItoKSignificance of anatomical properties of myocardial bridge on atherosclerosis evolution in the left anterior descending coronary arteryAtherosclerosis2006186238038916112675
- SpiroglouSGKostopoulosCGVarakisJNPapadakiHHAdipokines in periaortic and epicardial adipose tissue: differential expression and relation to atherosclerosisJ Atheroscler Thromb201017211513020145358
- LohmannCSchäferNvon LukowiczTAtherosclerotic mice exhibit systemic inflammation in periadventitial and visceral adipose tissue, liver, and pancreatic isletsAtherosclerosis2009207236036719481752
- TakaokaMSuzukiHShiodaSEndovascular injury induces rapid phenotypic changes in perivascular adipose tissueArterioscler Thromb Vasc Biol20103081576158220489168
- ChangLVillacortaLLiRLoss of perivascular adipose tissue on peroxisome proliferator-activated receptor-γ deletion in smooth muscle cells impairs intravascular thermoregulation and enhances atherosclerosisCirculation201212691067107822855570