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Vascular Health and Risk Management Volume 19, 2023 - Issue
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ORIGINAL RESEARCH

Ascorbic Acid vs Calcitriol in Influencing Monocyte Chemoattractant Protein-1, Nitric Oxide, Superoxide Dismutase, as Markers of Endothelial Dysfunction: In Vivo Study in Atherosclerosis Rat Model

Teuku Heriansyah1 Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Syiah Kuala, Banda Aceh, Aceh, IndonesiaORCID Iconhttps://orcid.org/0000-0002-0363-1997View further author information
ORCID Icon,
Herlina Dimiati1 Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Syiah Kuala, Banda Aceh, Aceh, IndonesiaORCID Iconhttps://orcid.org/0000-0002-3553-2301View further author information
ORCID Icon,
Tjut Farahiya Hadi1 Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Syiah Kuala, Banda Aceh, Aceh, IndonesiaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-2199-7757View further author information
ORCID Icon,
Dimas Arya Umara1 Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Syiah Kuala, Banda Aceh, Aceh, IndonesiaView further author information
,
Lian Varis Riandi2 Department of Parasitology, Faculty of Veterinary Medicine, Universitas Syiah Kuala, Banda Aceh, Aceh, IndonesiaView further author information
,
Fauzan Fajri3 Department of Animal Model, Faculty of Veterinary Medicine, Universitas Syiah Kuala, Banda Aceh, Aceh, IndonesiaView further author information
,
Sukmawan Fajar Santosa4 Integrated Research Laboratory, Faculty of Veterinary Medicine, Universitas Syiah Kuala, Banda Aceh, Aceh, IndonesiaView further author information
,
Titin Andri Wihastuti5 Department of Basic Nursing, Faculty of Health Sciences, Universitas Brawijaya, Malang, Jawa Timur, IndonesiaView further author information
&
Kumboyono Kumboyono6 Department of Nursing, Faculty of Health Sciences, Universitas Brawijaya, Malang, IndonesiaORCID Iconhttps://orcid.org/0000-0003-2124-8673View further author information
ORCID Icon show all
Pages 139-144 | Received 19 Dec 2022, Accepted 21 Feb 2023, Published online: 12 Mar 2023

References

  • Raisi Z, Cooper J, Salih A, et al. Cardiovascular disease and mortality sequelae of COVID-19 in the UK Biobank. Heart. 2023;109(2):119–126. doi:10.1136/heartjnl-2022-321492
  • Infusino F, Marazzato M, Mancone M, et al. Diet supplementation, probiotics, and nutraceuticals in SARS-CoV-2 infection: a scoping review. Nutrients. 2020;12(6):1718. doi:10.3390/nu12061718
  • Molinari C, Rizzi M, Squarzanti DF, Pittarella P, Vacca G, Renò F. 1,25-dihydroxycholecalciferol (Vitamin D3) induces NO-dependent endothelial cell proliferation and migration in a three-dimensional matrix. Cell Physiol Biochem. 2013;31(6):815–822. doi:10.1159/000350099
  • Grano A, De Tullio MC. Ascorbic acid as a sensor of oxidative stress and a regulator of gene expression: the Yin and Yang of vitamin C. Med Hypotheses. 2007;69(4):953–954. doi:10.1016/j.mehy.2007.02.008
  • Heller R, Unbehaun A, Schellenberg B, Mayer B, Werner-Felmayer G, Werner ER. l-ascorbic acid potentiates endothelial nitric oxide synthesis via a chemical stabilization of tetrahydrobiopterin. J Biol Chem. 2001;276(1):40–47. doi:10.1074/jbc.M004392200
  • Tabrizi R, Akbari M, Lankarani KB, Heydari ST, Kolahdooz F, Asemi Z. The effects of vitamin D supplementation on endothelial activation among patients with metabolic syndrome and related disorders: a systematic review and meta-analysis of randomized controlled trials. Nutr Metab. 2018;15(1):85. doi:10.1186/s12986-018-0320-9
  • Sokol SI, Srinivas V, Crandall JP, et al. The effects of vitamin D repletion on endothelial function and inflammation in patients with coronary artery disease. Vasc Med. 2012;17(6):394–404. doi:10.1177/1358863X12466709
  • Kim DH, Meza CA, Clarke H, Kim JS, Hickner RC. Vitamin D and Endothelial Function. Nutrients. 2020;12(2):575. doi:10.3390/nu12020575
  • Getz GS, Reardon CA. Animal models of atherosclerosis. ATVB. 2012;32(5):1104–1115. doi:10.1161/ATVBAHA.111.237693
  • Murwani S, Ali M, Muliartha K. Diet aterogenik pada tikus putih (Rattus norvegicus strain Wistar) sebagai model hewan aterosklerosis. JKB. 2006;22(1):6–9. doi:10.21776/ub.jkb.2006.022.01.2
  • Quincey A, Mohan S, Edderkaoui B. Monocyte chemotactic proteins mediate the effects of hyperglycemia in chondrocytes: in vitro studies. Life. 2022;12(6):836. doi:10.3390/life12060836
  • Shakouri Mahmoudabadi MM, Rahbar AR. Effect of EPA and Vitamin C on superoxide dismutase, glutathione peroxidase, total antioxidant capacity and malondialdehyde in type 2 diabetic patients. Oman Med J. 2014;29(1):39–45. doi:10.5001/omj.2014.09
  • Ladurner A, Schmitt CA, Schachner D, et al. Ascorbate stimulates endothelial nitric oxide synthase enzyme activity by rapid modulation of its phosphorylation status. Free Radic Biol Med. 2012;52(10):2082–2090. doi:10.1016/j.freeradbiomed.2012.03.022
  • Fernandez-Robredo P, González-Zamora J, Recalde S, et al. Vitamin D protects against oxidative stress and inflammation in human retinal cells. Antioxidants. 2020;9(9):838. doi:10.3390/antiox9090838
  • Wee CL, Mokhtar SS, Singh KKB, Yahaya S, Leung SWS, Rasool AHG. Calcitriol supplementation ameliorates microvascular endothelial dysfunction in Vitamin D-deficient diabetic rats by upregulating the vascular eNOS PROTEIN EXPRESSION AND REDUCING OXIDATIVE STress. Oxid Med Cell Longev. 2021;2021:1–11. doi:10.1155/2021/3109294
  • Dong J, Ling Wong S, Wai Lau C, et al. Calcitriol restores renovascular function in estrogen-deficient rats through downregulation of cyclooxygenase-2 and the thromboxane-prostanoid receptor. Kidney Int. 2013;84(1):54–63. doi:10.1038/ki.2013.12
  • Nakai K, Fujii H, Kono K, et al. Vitamin D activates the Nrf2-keap1 antioxidant pathway and ameliorates nephropathy in diabetic rats. Am J Hypertens. 2014;27(4):586–595. doi:10.1093/ajh/hpt160
  • Ma Q. Role of Nrf2 in oxidative stress and toxicity. Annu Rev Pharmacol Toxicol. 2013;53(1):401–426. doi:10.1146/annurev-pharmtox-011112-140320

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