Changes in LDL-C levels and goal attainment associated with addition of ezetimibe to simvastatin, atorvastatin, or rosuvastatin compared with titrating statin monotherapy

References

• BaigentCBlackwellLEmbersonJEfficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trialsLancet201037697531670168121067804
   PubMed Web of Science ®Google Scholar
• CatapanoALReinerZDe BackerGESC/EAS Guidelines for the management of dyslipidaemias. The Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS)Atherosclerosis2011217134621882396
   PubMed Web of Science ®Google Scholar
• GrundySMCleemanJIMerzCNImplications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III GuidelinesJ Am Coll Cardiol200444372073215358046
   PubMedGoogle Scholar
• FoodyJMSajjanSGHuXHLoss of early gains in low-density lipoprotein cholesterol goal attainment among high-risk patientsJ Clin Lipidol20104212613221122640
   PubMed Web of Science ®Google Scholar
• NicholsGANagSChanWIntensity of lipid-lowering therapy and low-density lipoprotein cholesterol goal attainment among the elderly before and after the 2004 National Cholesterol Education Program Adult Treatment Panel III updateAm Heart J2007154355456017719305
   PubMed Web of Science ®Google Scholar
• WatersDDBrotonsCChiangCWLipid treatment assessment project 2: a multinational survey to evaluate the proportion of patients achieving low-density lipoprotein cholesterol goalsCirculation20091201283419546386
   PubMed Web of Science ®Google Scholar
• KauffmanABOlsonKLYoungbloodMLAttainment of low-density lipoprotein cholesterol goals in coronary artery diseaseJ Clin Lipidol20104317318021122649
   PubMed Web of Science ®Google Scholar
• KitkungvanDLynn FilliponNMDaniSSDowneyBCLow-density lipoprotein cholesterol target achievement in patients at high risk for coronary heart diseaseJ Clin Lipidol20104429329721122662
   PubMed Web of Science ®Google Scholar
• NagSSDanielGWBullanoMFLDL-C goal attainment among patients newly diagnosed with coronary heart disease or diabetes in a commercial HMOJ Manag Care Pharm200713865266317970603
   PubMed Web of Science ®Google Scholar
• CatapanoALTothPPTomassiniJETershakovecAMThe efficacy and safety of ezetimibe co-administered with statin therapy in various patient groupsClin Lipidol2012811341
   Google Scholar
• TothPPBallantyneCMDavidsonMHChanges in prescription patterns before and after reporting of the Ezetimibe and Simvastatin in Hypercholesterolemia Enhances Atherosclerosis Regression trial (ENHANCE) results and expected effects on low-density lipoprotein-cholesterol reductionJ Clin Lipidol20126218019122385552
   PubMed Web of Science ®Google Scholar
• Crestor (rosuvastatin calcium) tablets [package insert]Wilmington, DEAstraZeneca2013
   Google Scholar
• Lipitor (atorvastatin calcium) tablets [package insert]New York, NYPfizer2013
   Google Scholar
• Zocor (simvastatin) tablets [package insert]Whitehouse Station, NJMerck & Co Inc2012
   Google Scholar
• Liptruzet (ezetimibe/atorvastatin) [package insert]Whitehouse Station, NJMerck & Co Inc2013
   Google Scholar
• Vytorin (ezetimibe/simvastatin) [package insert]Whitehouse Station, NJMerck & Co Inc2013
   Google Scholar
• BallantyneCMBlazingMAKingTRBradyWEPalmisanoJEfficacy and safety of ezetimibe co-administered with simvastatin compared with atorvastatin in adults with hypercholesterolemiaAm J Cardiol200493121487149415194018
   PubMed Web of Science ®Google Scholar
• BallantyneCMAbateNYuanZKingTRPalmisanoJDose-comparison study of the combination of ezetimibe and simvastatin (Vytorin) versus atorvastatin in patients with hypercholesterolemia: the Vytorin Versus Atorvastatin (VYVA) studyAm Heart J2005149346447315864235
   PubMed Web of Science ®Google Scholar
• WeinstockRSGoldbergRBGuytonJREffect of ezetimibe/simvastatin vs atorvastatin on lowering levels of LDL-C and non-HDL-C, ApoB, and hs-CRP in patients with type 2 diabetesJ Clin Lipidol200821253521291712
   PubMed Web of Science ®Google Scholar
• BaysHEOseLFraserNA multicenter, randomized, double-blind, placebo-controlled, factorial design study to evaluate the lipid-altering efficacy and safety profile of the ezetimibe/simvastatin tablet compared with ezetimibe and simvastatin monotherapy in patients with primary hypercholesterolemiaClin Ther200426111758177315639688
   PubMed Web of Science ®Google Scholar
• CatapanoALDavidsonMHBallantyneCMLipid-altering efficacy of the ezetimibe/simvastatin single tablet versus rosuvastatin in hypercholesterolemic patientsCurr Med Res Opin200622102041205317022864
   PubMed Web of Science ®Google Scholar
• PearsonTADenkeMAMcBridePEA community-based, randomized trial of ezetimibe added to statin therapy to attain NCEP ATP III goals for LDL cholesterol in hypercholesterolemic patients: the ezetimibe add-on to statin for effectiveness (EASE) trialMayo Clin Proc200580558759515887425
   PubMed Web of Science ®Google Scholar
• KosoglouTStatkevichPYangBPharmacodynamic interaction between ezetimibe and rosuvastatinCurr Med Res Opin20042081185119515324521
   PubMed Web of Science ®Google Scholar
• BallantyneCMWeissRMoccettiTEfficacy and safety of rosuvastatin 40 mg alone or in combination with ezetimibe in patients at high risk of cardiovascular disease (results from the EXPLORER study)Am J Cardiol200799567368017317370
   PubMed Web of Science ®Google Scholar
• SteinbergBABhattDLMehtaSNine-year trends in achievement of risk factor goals in the US and European outpatients with cardiovascular diseaseAm Heart J2008156471972718926153
   PubMed Web of Science ®Google Scholar
• Vande GriendJPSaseenJJLow-density lipoprotein cholesterol goal attainment in high-risk family medicine patientsJ Clin Lipidol20093319520021291814
   PubMed Web of Science ®Google Scholar
• TothPPCatapanoATomassiniJETershakovecAMUpdate on the efficacy and safety of combination ezetimibe plus statin therapyClin Lipidol201055655684
   Web of Science ®Google Scholar
• AronowHDHessGHillJKuznikALiuLZSwitching from atorvastatin to simvastatin in patients at high cardiovascular risk: effects on low-density lipoprotein cholesterolAm J Ther201017216717519770794
   PubMed Web of Science ®Google Scholar
• AtarDCarmenaRClemmensenPClinical review: impact of statin substitution policies on patient outcomesAnn Med200941424225619191052
   PubMed Web of Science ®Google Scholar
• AthyrosVGTziomalosKKaragiannisAMikhailidisDPTo switch (statins) or not to switch? That is the questionExpert Opin Pharmacother201011182943294620958109
   PubMed Web of Science ®Google Scholar
• JonesPHDavidsonMHSteinEAComparison of the efficacy and safety of rosuvastatin versus atorvastatin, simvastatin, and pravastatin across doses (STELLAR* Trial)Am J Cardiol200392215216012860216
   PubMed Web of Science ®Google Scholar
• MikhailidisDPSibbringGCBallantyneCMDaviesGMCatapanoALMeta-analysis of the cholesterol-lowering effect of ezetimibe added to ongoing statin therapyCurr Med Res Opin20072382009202617659159
   PubMed Web of Science ®Google Scholar
• TunceliKSajjanSGRameyDRSwitching from high-efficacy lipid-lowering therapies to simvastatin and low-density lipoprotein cholesterol goal attainment in coronary heart disease/coronary heart disease-equivalent patientsJ Clin Lipidol20104649150021122696
   PubMed Web of Science ®Google Scholar
• WilleyVJBullanoMFShoetanNNGandhiSKTherapy modifications and low-density lipoprotein cholesterol goal attainment rates associated with the initiation of generic simvastatinCurr Med Res Opin201026112112819916706
   PubMed Web of Science ®Google Scholar
• KaralisDGVictorBAhedorLLiuLUse of lipid-lowering medications and the likelihood of achieving optimal LDL-cholesterol goals in coronary artery disease patientsCholesterol2012201286192422888414
   PubMedGoogle Scholar
• CaliffRMLokhnyginaYCannonCPAn update on the IMProved reduction of outcomes: Vytorin Efficacy International Trial (IMPROVE-IT) designAm Heart J2010159570570920435175
   PubMed Web of Science ®Google Scholar
• BaigentCLandrayMJReithCThe effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trialLancet201137797842181219221663949
   PubMed Web of Science ®Google Scholar
• HolmeIBomanKBrudiPObserved and predicted reduction of ischemic cardiovascular events in the Simvastatin and Ezetimibe in Aortic Stenosis trialAm J Cardiol2010105121802180820538134
   PubMed Web of Science ®Google Scholar
• RosseboABPedersenTRBomanKIntensive lipid lowering with simvastatin and ezetimibe in aortic stenosisN Engl J Med2008359131343135618765433
   PubMed Web of Science ®Google Scholar