Studies on free radicals, antioxidants, and co-factors

References

• AgarwalRSSohalRS1996Relationship between susceptibility to protein oxidation, aging, and maximum life span potential of different speciesExp Gerontol31365729415119
   PubMed Web of Science ®Google Scholar
• AgarwalSRaoAV1998Tomato lycopene and low density lipoprotein oxidation; a human dietary intervention studyLipids33981849832077
   PubMed Web of Science ®Google Scholar
• AgilADurảnRBarreroF2006Plasma lipid peroxidation in sporadic Parkinson’s: Role of the L-dopaJ Neuro Scien240316
   Web of Science ®Google Scholar
• AksoyPWhiteTAThompsonM2006Regulation of intracellular levels of NAD: A novel role for CD38Biochem Biophys Res Comm34513869216730329
   PubMed Web of Science ®Google Scholar
• AlalufSMuir-HowieHHuHL2000Atmospheric oxygen accelerates the induction of a post-mitotic phenotype in human dermal fibroblasts: the key protective role of glutathioneDifferentiation Res Biol Diversity6614755
   PubMed Web of Science ®Google Scholar
• AlulRHWoodMLongoJ2003Vitamin C protects low-density lipoprotein from homocysteine-mediated oxidationFree Rad Bio Med348819112654477
   PubMed Web of Science ®Google Scholar
• AlexandrovaMBochevPMarkovaV2004Dynamics of free radical processes in acute ischemic stroke: influence on neurological status and outcomeJ Clin Neurosci11501615177393
   PubMed Web of Science ®Google Scholar
• AmesBNShigenagaMKHagenTM1993Oxidants, antioxidants and degenerative diseases of agingProc Natl Acad Sci907915228367443
   PubMed Web of Science ®Google Scholar
• AmesBNShigenagaMK1992Oxidants are a major contributor to agingAnn NY Acad Sci66385961482105
   PubMed Web of Science ®Google Scholar
• AndersonJWGowriMSTurnerJ1999Antioxidant supplementation effects on low-density lipoprotein oxidation for individuals with type 2 diabetes mellitusJ Am Coll Nutr184516110511327
   PubMed Web of Science ®Google Scholar
• AndrikopoulosNKKalioraACAssimopoulouAN2002Inhibitory activity of minor polyphenolic and nonpolyphenolic constituents of olive oil against in vitro low-density lipoprotein oxidationJ Med Food51712511107
   PubMedGoogle Scholar
• AnlasikTSiesHGriffithsHR2005Dietary habits are major determinants of the plasma antioxidant status in healthy elderly subjectsBrit J Nutr946394216277763
   PubMed Web of Science ®Google Scholar
• ArmbrechtHJ2001The biology of ageingJ Lab Clin Med138220511574815
   PubMed Web of Science ®Google Scholar
• ArredondoMNúñezMT2005Iron and copper metabolismMol Aspects Med263132716112186
   PubMedGoogle Scholar
• ArtsICHollmanPCFeskensEJ2001Catechin intake might explain the inverse relation between tea consumption and ischemic heart disease: the Zutphen Elderly StudyAm J Clin Nutr742273211470725
   PubMed Web of Science ®Google Scholar
• AtliTKevenKAvciA2004Oxidative stress and antioxidant status in elderly diabetes mellitus and glucose intolerance patientsArch Geront Geriatr3926975
   PubMed Web of Science ®Google Scholar
• BalabanRSNemotoSFinkelT2005Mitochondria, Oxidants, and AgingCell Vol12048395
   PubMed Web of Science ®Google Scholar
• BaydasGReiterRJYaserA2003Melatonin produces glial reactivity in the hippocampus, cortex, and cerebellum of streptozocin-induced diabetic ratsFree Rad Bio Med3579780414583344
   PubMed Web of Science ®Google Scholar
• BehlCDavisJBLesleyR1994Hydrogen peroxide mediates amyloid protein activityCell77817278004671
   PubMed Web of Science ®Google Scholar
• BellomoGMirabelliF1992Oxidative stress and cytoskeletal alterationsAnn NY Acad Sci663971091482106
   PubMed Web of Science ®Google Scholar
• BharathSAndersonJK2005Glutathione depletion in a midbrain-derived immortalized dopaminergic cell line results in limited tyrosine nitration of mitochondrial complex I subunits: implications for Parkinson’s diseaseAntioxid Redox Signal79001015998245
   PubMed Web of Science ®Google Scholar
• BiesalskiHK2002Free radical theory of ageingCurr Opin Clin Nutr Metab Care551011790942
   PubMed Web of Science ®Google Scholar
• Ble-CastilloJLCarmona-DíazEMéndezJD2005Effect of α-tocopherol on the metabolic control and oxidative stress in female type 2 diabeticsBiomed Pharmacother59290515932790
   PubMed Web of Science ®Google Scholar
• BlockG1991Vitamin C and cancer prevention; the epidemiological evidenceAm J Clin Nutr53270S82S1985398
   PubMed Web of Science ®Google Scholar
• BonakdarRAGuarneriE2005Coenzyme Q10Am Fam Physician7210657016190504
   PubMed Web of Science ®Google Scholar
• Bonnefont-RousselotD2004The role of antioxidant micronutrients in the prevention of diabetic complicationsTreat Endocrinol3415215743112
   PubMedGoogle Scholar
• BorekC2005Antioxidants and the prevention of hormonally regulated cancerThe J Mens Health Gender234652
   Google Scholar
• Bourd-MarchassonIDelmas-BeauvieuxMCPeuchantE2001Antioxidant defenses and oxidative markers in erythrocytes and plasma from normally nourished elderly Alzheimer patientsAge Ageing302354111443025
   PubMed Web of Science ®Google Scholar
• BrenneisenPSteinbrennerHHelmutSies2005Selenium, oxidative stress, and health aspectsMol Aspects Med262566716105679
   PubMedGoogle Scholar
• ButterfieldDACastegnaADrakeJ2002Vitamin E and neurodegenerative disorders associated with oxidative stressNutr Neurosci52293912168685
   PubMed Web of Science ®Google Scholar
• CadenasEDaviesKJA2000Mitochondrial free radical generation, oxidative stress, and agingFree Rad Biol Med292223011035250
   PubMed Web of Science ®Google Scholar
• CadenasESiesH1998The lag phaseFree Rad Res286019
   PubMed Web of Science ®Google Scholar
• CadenasE1989Biochemistry of oxygen toxicityAnn Rev Biochem58791102673022
   PubMed Web of Science ®Google Scholar
• CalabreseVScapagniniGColombritaC2003Redox regulation of heat shock protein expression in aging and neurodegenerative disorders associated with oxidative stress: a nutritional approachAmino Acids254374414661103
   PubMed Web of Science ®Google Scholar
• CamMYavuzOGuvenA2003Protective effects of chronic melatonin treatment against renal injury in strptozocin-induced diabetic ratsJ Pineal Res352122012932206
   PubMed Web of Science ®Google Scholar
• CaoGSoficEPriorRL1997Antioxidant and prooxidant behavior of flavonoids: structure-activity relationshipsFree Rad Biol Med22749609119242
   PubMed Web of Science ®Google Scholar
• CarrAFreiB1999Does Vitamin C act as a pro-oxidant under physiological conditions?FASEB J1310072410336883
   PubMed Web of Science ®Google Scholar
• CarrollYLCorridanBMMorrisseyPA2000Lipoprotein carotenoid profiles and the susceptibility of low density lipoprotein to oxidative modification in healthy elderly volunteersEur J Clin Nutr54500710878653
   PubMed Web of Science ®Google Scholar
• CetinkayaABulbulogluEKantarcekenB2006Effects of L-carnitine on oxidant/antioxidant status in acetic acid-induced colitisDig Dis Sci514889416614957
   PubMed Web of Science ®Google Scholar
• ChangBNishikawaMNishihuchiS2005L-carnitine inhibits hepatocarcinogenesis via protection of mitochondriaInt J Cancer1137192915499623
   PubMed Web of Science ®Google Scholar
• ChattopadhyayABandyopadhyayD2006Vitamin E in the prevention of ischemic heart diseasePharmacol Rep581798716702619
   PubMed Web of Science ®Google Scholar
• ChaudièreJFerrari-IliouR1999Intracellular Antioxidants: from chemical to biochemical mechanismsFood Chem Toxicol379496210541450
   PubMed Web of Science ®Google Scholar
• ChenYSaariJTKangYJ1994Weak antioxidant defenses make the heart a target for damage in copper-deficient ratsFree Rad Bio Med17529367867969
   PubMed Web of Science ®Google Scholar
• CherubiniARuggieroCCristinaM2005aPotential markers of oxidative stress in strokeFree Rad Biol Med398415216140205
   PubMed Web of Science ®Google Scholar
• CherubiniAVignaGBZulianiG2005bRole of antioxidants an atherosclerosis: epidemiological and clinical updateCurr Pharm Des1120173215974956
   PubMed Web of Science ®Google Scholar
• ChoiJSullardsMCOlzmannJA2006Oxidative damage of DJ-1 is linked to sporadic Parkinson and Alzheimer diseasesJ Biol Chem281108162416517609
   PubMed Web of Science ®Google Scholar
• ConnerEMGrishamMB1996Inflammation, free radicals, and antioxidantsNutrition1227478862535
   PubMed Web of Science ®Google Scholar
• ConquerJAMaianiGAzziniE1998Supplementation with quercetin markedly increases quercetin concentrations without effect on selected risk factors for heart disease in healthy subjectsJ Nutr12859379482769
   PubMed Web of Science ®Google Scholar
• CookeMSEvansMDDizdarogluM2003DNA damage: mechanisms, mutation, and diseaseFASEB J17119521412832285
   PubMed Web of Science ®Google Scholar
• CummingRGMitchellPWayneS2000Diet and cataract. The blue mountains eye studyOphthalmology107450610711880
   PubMed Web of Science ®Google Scholar
• DarkoDDornhorstAKellyFJ2002Lack of effect of vitamin C on blood pressure, oxidative stress and endothelial function in Type II diabetesClin Sci1033394412241530
   PubMed Web of Science ®Google Scholar
• DeschampsVBarbereger-GateauPPeuchantE2001Nutritional factors in cerebral aging and dementia: epidemiological arguments for a role of oxidative stressNeuroepidemolog20715
   PubMed Web of Science ®Google Scholar
• Dieber-RothenederMPuhlHWaegG1991Effect of oral supplementation with D-∝-tocopherol on the Vitamin E content of human low density lipoproteins and resistance to oxidationJ Lipid Res321325321770314
   PubMed Web of Science ®Google Scholar
• DizdarogluMJarugaPBirinciogluM2002Free-radical-induced damage to DNA: mechanisms and measurementFree Rad Bio Med3211021512031895
   PubMed Web of Science ®Google Scholar
• DonaldsonMS2004Nutrition and cancer: a review of the evidence for an anti-cancer dietNutr J3194015496224
   PubMed Web of Science ®Google Scholar
• DreherDJunodAF1996Role of oxygen free radicals in cancer developmentEur J Cancer32A3088695238
   PubMed Web of Science ®Google Scholar
• DrögeW2002Aging-related changes in the thiol/disulfide redox state: implications for the use of thiol antioxidantsExper Geront37133345
   PubMed Web of Science ®Google Scholar
• DyrksTDyrksEMastersCL1993Amyloidogenicity of rodent and human beta A4 sequencesFEBS Lett32423168508926
   PubMed Web of Science ®Google Scholar
• DzauVJBraun-DullaeusRCSeddingDG2002Vascular proliferation and atherosclerosis: new perspectives and therapeutic strategiesNat Ned8124956
   Google Scholar
• ElahiMMMatataBM2006Free radicals in blood: Evolving concepts in the mechanism of ischemic heart diseaseArch Biochem Biophys450788816620764
   PubMed Web of Science ®Google Scholar
• EliRFascianoJA2006An adjunctive preventive treatment for cancer: Ultraviolet light and ginkgo biloba, together with other antioxidants, are a safe and powerful, but largely ignored, treatment option for the prevention of cancerMedical Hypothesis6611526
   Web of Science ®Google Scholar
• EmeritJEdeasMBricaireF2004Neurodegenerative diseases and oxidative stressBiomed Pharmacother58394614739060
   PubMed Web of Science ®Google Scholar
• FarvidMSSiassiFJalaliM2004The impact of vitamin and/or mineral supplementation on lipid profiles in type 2 diabetesJ Am Coll Nutr23272915190052
   PubMed Web of Science ®Google Scholar
• FasanoMBergamascoBLopianoL2006Modifications of the iron-neuromelanin in Parkinson’s diseaseJ Neurochem969091616417570
   PubMed Web of Science ®Google Scholar
• FengYPaulIALeBlancMH2006Nicotinamide reduces hypoxic ischemic brain injury in the newborn ratBrain Res Bull691172216533659
   PubMed Web of Science ®Google Scholar
• FinkelTHolbrookNJ2000Oxidants, oxidative stress and the biology of ageingNature4082394711089981
   PubMed Web of Science ®Google Scholar
• FloydRAHensleyK2002Oxidative stress in brain aging. Implications for therapeutics of neurodegenerative diseasesNeurobiol Aging2379580712392783
   PubMed Web of Science ®Google Scholar
• FrankBGuptaS2005A review of antioxidants and Alzheimer’s diseaseAnn Clin Psychiatry172698616402761
   PubMedGoogle Scholar
• FreiBHigdonJV2003Antioxidant activity of tea phenols in vivo: evidence from animal studiesJ Nutr1333275S84S14519826
   PubMed Web of Science ®Google Scholar
• FukaiTFolzRJLandmesserU2002Extracellular superoxide dismutase and cardiovascular diseaseCardiovasc Res552394912123763
   PubMed Web of Science ®Google Scholar
• GalleJHansen-HaggeTWannerCSeiboldS2006Impact of oxidized low density lipoprotein on vascular cellsAtherosclerosis1852192616288760
   PubMed Web of Science ®Google Scholar
• GeleijnseJMLaunerLJHofmanA1999Tea flavonoids may protect against atherosclerosis. The Rotterdam studyArch Intern Med1592170410527294
   PubMed Web of Science ®Google Scholar
• GengZLauBHS1997Aged garlic extract modulates redox cycle and superoxide dismutase activity in vascular endothelial cellsPhytother Res11546
   Web of Science ®Google Scholar
• GibsonGEZhangH2002Interactions of oxidative stress with thiamine homeostasis promote neurodegenerationNeurochem Intern40493504
   PubMed Web of Science ®Google Scholar
• Gilgun-SherkiYMelamedEOffenD2001Oxidative stress induced-neurodegenerative diseases: the need for antioxidants that penetrate the blood brain barrierNeuropharmacology409597511406187
   PubMed Web of Science ®Google Scholar
• GladeMJ2003The role of reactive oxygen species in Health and Disease Northeast Regional Environmental Public Health Center University of MassachusettsAmerst Nutrition194013
   Google Scholar
• GooderhamMHAdlercreutzHOjalaST1996A soy protein isolate rich in genistein and daidzein and its effects on plasma isoflavone concentrations, platelet aggregation, blood lipids and fatty acid composition of plasma phospholipids in normal menJ Nutr126200068759372
   PubMed Web of Science ®Google Scholar
• GramignanoGLussoMRMadedduC2006Efficacy of L-carnitine administration on fatigue, nutritional status, oxidative stress, and related quality of life in 12 advanced cancer patients undergoing anticancer therapyNutrition221364516459226
   PubMed Web of Science ®Google Scholar
• Guerrero-RomeroFRodríguez-MoránM2005Complementary therapies for diabetes: The case for chromium, magnesium, and antioxidantsArch Med Res36250715925015
   PubMed Web of Science ®Google Scholar
• GuptaMDobashiKGreeneJK1997Studies on hepatic injury and antioxidant enzyme activities in rat sub-cellular organelles following in vivo ischemia and reperfusionMol Cell Biochem176337479406179
   PubMed Web of Science ®Google Scholar
• GutteridgeJM1995Lipid peroxidation and antioxidants as biomarkers of tissue damageClin Chem411819287497639
   PubMed Web of Science ®Google Scholar
• HaldALothariusJ2005Oxidative stress and inflammation in Parkinson’s disease: is there a casual link?Exp Neurol1932799015869932
   PubMed Web of Science ®Google Scholar
• HalliwellB1996Antioxidants in human health and diseaseAnn Rev Nutr1633508839918
   PubMed Web of Science ®Google Scholar
• HammerstoneJFLazarusSASchmitzHH2000Procyanidin content and variation in some commonly consumed foodsJ Nutr1302086S92S10917927
   PubMed Web of Science ®Google Scholar
• HardlandRPandi-PerumalSRCardinaliDP2006MelatoninInt J Biochem Cell Biol383131616219483
   PubMed Web of Science ®Google Scholar
• HarmanD1956Ageing: a theory based on free radical and radiation chemistryJ Gerontol229830013332224
   PubMedGoogle Scholar
• HedgePSRajasekaranNSChandraTS2205Effects of the antioxidant properties of millet species on oxidative stress and glycemic status in alloxan-induced ratsNutr Res25110920
   Google Scholar
• HeitzerTYla HerttualaSWildE1999Effect of Vitamin E on endothelial vasodilator function in patients with hypercholesterolemia, chronic smoking or bothJ Am Coll Cardiol334995059973031
   PubMed Web of Science ®Google Scholar
• HellmanNEGitilinJD2002Ceruloplasmin metabolism and functionAnn Rev Nutr224395812055353
   PubMed Web of Science ®Google Scholar
• HensleyKBenakassEJBolliR2004New perspectives on vitamin E: γ-tocopherol and carboxyethylhydroxychroman metabolites in biology and medicineFree Rad Biol Med3611514732286
   PubMed Web of Science ®Google Scholar
• HertogMGLFeskensEJMHollmanPCH1993Dietary antioxidant flavonoids and risk of coronary heart disease: the Zupthen elderly studyLancet342100710118105262
   PubMed Web of Science ®Google Scholar
• HoE2004Zinc deficiency, DNA damage and cancer riskJ Nutr Biochem15572815542347
   PubMed Web of Science ®Google Scholar
• HodisHNMackWJLaBreeL2002Alpha-tocopherol supplementation in healthy individuals reduces low-density lipoprotein oxidation but not atherosclerosis: the Vitamin E Atherosclerosis Prevention Study (VEAPS)Circulation1061453912234947
   PubMed Web of Science ®Google Scholar
• HolmgrenA1985ThioredoxinAnn Rev Biochem54237713896121
   PubMed Web of Science ®Google Scholar
• HuangCHuangYLiJ2002Inhibition of benzo(a)pyrene diol-epoxide-induced transactivation of activated protein 1 and nuclear factor kappaB by black raspberry extractsCancer Res6268576312460899
   PubMed Web of Science ®Google Scholar
• InnesAJKennedyGMcLarenM2003Dark chocolate inhibits platelet aggregation in healthy volunteersPlatelets14325712944249
   PubMed Web of Science ®Google Scholar
• InoueMSatoEFNishikawaM2003Mitochondrial generation of reactive oxygen species and its role in aerobic lifeCurr Med Chem10249550514529465
   PubMed Web of Science ®Google Scholar
• IssaAYVolateSRWargovichMJ2006The role of phytochemicals in inhibition of cancer and inflammation: New directions and perspectivesJ Food Comp Analysis1940519
   Web of Science ®Google Scholar
• IzzottiABagnisASaccàSC2006The role of oxidative stress in glaucomaMutation Res6121051416413223
   PubMed Web of Science ®Google Scholar
• JayDHitomiHGriendlingKK2006Oxidative stress and diabetic cardiovascular complicationsFree Rad Biol Med401839216413400
   PubMed Web of Science ®Google Scholar
• JenkinsBGKoroshetzWJBealMF1993Evidence for impairment of energy metabolism in vivo in Huntington’s disease using localized 1H NMR spectroscopyNeurology432689958255479
   PubMed Web of Science ®Google Scholar
• KalioraACDedoussisGVZSchmidtH2006Dietary antioxidants in preventing atherogenesisAtherosclerosis18711716313912
   PubMed Web of Science ®Google Scholar
• KamatJPDevasagayamTP1999Nicotinamide (vitamin B3) as an effective antioxidant against oxidative damage in rat brain mitochondriaRedox Rep41798810658823
   PubMed Web of Science ®Google Scholar
• KarasekM2004Melatonin, human aging, and age-related diseasesExp Geront3917239
   PubMed Web of Science ®Google Scholar
• KarouiHHoggNFrejavilleC1996Characterization of sulfur-centered radical intermediates formed during the oxidation of thiols and sulfite by peroxynitrite-ESR-SPIN trapping and oxygen uptake studiesJ Biol Chem271600098626383
   PubMed Web of Science ®Google Scholar
• KeaneyJFJrGuoYCunninghamD1993Dietary antioxidants preserve endothelium-dependent vessel relaxation in cholesterol-fed rabbitsProc Natl Acad Sci USA901188048265642
   PubMed Web of Science ®Google Scholar
• KlaunigJEKamendulisLM2004The role of oxidative stress in carcinogenesisAnn Rev Pharmacol Toxicol442396714744246
   PubMed Web of Science ®Google Scholar
• KnoopsKTBGrootLCPGM deKromhoutD2004Mediterranean diet, lifestyle factors, and 10-year mortality in elderly European men and women: the HALE projectJ Amer Med Asso29214339
   PubMed Web of Science ®Google Scholar
• KojoS2004Vitamin C: basic metabolism and its function as an index of oxidative stressCurr Med Chem1110416415078165
   PubMed Web of Science ®Google Scholar
• KorolainenMAGoldsteinsGTuulaA2006Oxidative modification of proteins in the frontal cortex of Alzheimer’s disease brainNeuro Biol Aging274253
   PubMed Web of Science ®Google Scholar
• KorotchkinaLGSidhuSPatelMS2004R-lipoic acid inhibits mammalian pyruvate dehydrogenase kinaseFree Rad Res38108392
   PubMed Web of Science ®Google Scholar
• KowaldAKirkwoodTB2000Accumulation of defective mitochondria through delayed degradation of damaged organelles and its possible role in ageing of post-mitotic and dividing cellsJ Theor Biol2021456010640434
   PubMed Web of Science ®Google Scholar
• KuHHBrunkUTSohalRS1993Relationship between mitochondrial superoxide and hydrogen peroxide production and longevity of mammalian speciesFree Rad Biol Med1562178138188
   PubMed Web of Science ®Google Scholar
• KuppusamyURDharmaniMKanthimathiMS2005Antioxidant enzyme activities of human peripheral blood mononuclear cells exposed to trace elementsBiol Trace Element Res1062939
   Web of Science ®Google Scholar
• LandisGNTowerJ2005Superoxide dismutase evolution and life span regulationMech Ageing Dev1263657915664623
   PubMed Web of Science ®Google Scholar
• LangsjoenPHLangsjoenAM1999Overview of the use of CoQ10 in cardiovascular diseaseBiofactors92738410416041
   PubMed Web of Science ®Google Scholar
• LauFCShukitt-HaleBJosephJA2005The beneficial effects of fruit polyphenols on brain agingNeurobiol Aging261283216194581
   PubMed Web of Science ®Google Scholar
• LeeDHFolsomARHarnackL2004Does supplemental vitamin C increase cardiovascular disease risk in women with diabetes?Am J Clin Nutr801194200015531665
   PubMed Web of Science ®Google Scholar
• LeonardSSHarrisGKShiXL2004Metal-induced oxidative stress and signal transductionFree Rad Biol Med3719214215544913
   PubMed Web of Science ®Google Scholar
• LeungFY1998Trace elements that act as antioxidants in parenteral micronutritionJ Nutr Biochem93047
   Web of Science ®Google Scholar
• LevyYZaltsbergHBen-AmotzA2000Dietary supplementation of a natural isomer mixture of β-carotene inhibits oxidation of LDL derived from patients with diabetes mellitusAnn Nutr Metab44546010970993
   PubMed Web of Science ®Google Scholar
• LittarruGPTianoL2005Clinical aspects of coenzyme Q10: an updateCurr Opin Clin Metab Care86416
   PubMed Web of Science ®Google Scholar
• LiuRYZhouJNJ van HeerikhuizeMA1999Decreased melatonin levels in postmortem cerebrospinal fluid in relation to aging, Alzheimer’s’ disease, and apolipoprotein E-epsilon4/4 genotypeJ Clin Endocrinol Metab8432379920102
   PubMed Web of Science ®Google Scholar
• LoftSPoulsenHE1996Cancer risk and oxidative DNA damage in manJ Mol Med742973128862511
   PubMed Web of Science ®Google Scholar
• LopaczynskiWZeiselSH2001Antioxidants, programmed cell death, and cancerNutr Res21295307
   Web of Science ®Google Scholar
• LoweNMFraseWDJacksonMJ2002Is there a potential therapeutic value of copper and zinc for osteoporosis?Proc Nutr Soc61181512133199
   PubMed Web of Science ®Google Scholar
• LuchsingerJATangMXSheaS2003Antioxidant vitamin intake and risk of Alzheimer diseaseArch Neurol60203812580704
   PubMed Web of Science ®Google Scholar
• MainousAGWellsBJKoopmanRJ2005Iron, lipids, and risk of cancer in the Framingham Offspring cohortAm J Epidemiol16111152215937020
   PubMed Web of Science ®Google Scholar
• MajeedAAylinP2005The ageing population of the United Kingdom and cardiovascular diseaseBMJ331136216339247
   PubMed Web of Science ®Google Scholar
• MandelSPackerLMoussaBH2005Proceedings from the “Third International Conference on mechanism of Action of Nutraceuticals”J Nutr Biochem165132016115539
   PubMed Web of Science ®Google Scholar
• MantenaSKKatiyarSK2006Grape seed proanthocyanidins inhibit UV-radiation-induced oxidative stress and activation of MAPK and NF-κB signaling in human epidermal keratinocytesFree Rad Biol Med4016031416632120
   PubMed Web of Science ®Google Scholar
• MantheyKCRodriguez-MelendezRHoiJT2006Riboflavin deficiency causes protein and DNA damage in HepG2 cells, triggering arrest in G1 phase of the cell cycleJ Nutr Biochem17250616109485
   PubMed Web of Science ®Google Scholar
• MargolisRLRossCA2003Diagnosis of Huntington’s diseaseClin Chem4917263214500613
   PubMed Web of Science ®Google Scholar
• MarianiEPolidoriMCCherubiniA2005Oxidative stress in brain aging, neurodegenerative and vascular diseases: An overviewJ Chromat B8276575
   PubMed Web of Science ®Google Scholar
• MarnettLJ2000Oxyradicals and DNA damageCarcinogenesis213617010688856
   PubMed Web of Science ®Google Scholar
• MasellaRDi BenedettoRVariR2005Novel mechanisms of natural antioxidant compounds in biological systems: involvement of glutathione and glutathione-related enzymesJ Nutr Biochem165778616111877
   PubMed Web of Science ®Google Scholar
• MatesJMPerez-GomezCDe CastroIN1999Antioxidant enzymes and human diseasesClin Biochem3259560310638941
   PubMed Web of Science ®Google Scholar
• McCallMRFreiB1999Can antioxidant vitamins materially reduce oxidative damage in humans?Free Rad Biol Med2610345310232849
   PubMed Web of Science ®Google Scholar
• McEligotAJYangSMeyskensFL2005Redox regulation by intrinsic species and extrinsic nutrients in normal and cancer cellsAnn Rev Nutr252619516011468
   PubMed Web of Science ®Google Scholar
• MeococciPPolidoriMCIngegniT1998Oxidative damage to DNA in lymphocytes from AD patientsNeurology511014179781522
   PubMed Web of Science ®Google Scholar
• MeydaniM2001Nutrition interventions in aging and age-associated diseasesAnn NY Acad Sci9282263511795514
   PubMed Web of Science ®Google Scholar
• MiglioreLPetrozziLLucettiC2002Oxidative damage and cytogenetic analysis in leukocytes of Parkinson’s disease patientsNeurology5818091512084881
   PubMed Web of Science ®Google Scholar
• MillerERPastor-BarriusoDDalalRA2005Meta-analysis: high-dosage Vitamin E supplementation may increase all-cause mortalityAnn Intern Med142374615537682
   PubMed Web of Science ®Google Scholar
• MiquelJRamirez-BoscaARamirez-BoscaJV2006Menopause: a review on the role of oxygen stress and favorable effects of dietary antioxidantsArch Gerontol Geriatr4228930616442644
   PubMed Web of Science ®Google Scholar
• MontineTJBealMFRobertsonD1999Cerebrospinal fluid F2-isoprostanes are elevated in Huntington’s diseaseNeurology521104510102447
   PubMed Web of Science ®Google Scholar
• MooreDJWestABDawsonVL2005Molecular pathology of Parkinson’s diseaseAnnu Rev Neurosci28578716022590
   PubMed Web of Science ®Google Scholar
• MortensenASkibstedLHTruscottTG2001The interaction of dietary carotenoids with radical speciesArch Biochem Biophs3851319
   PubMed Web of Science ®Google Scholar
• MunteanuAZinggJMAzziA2004Anti-atherosclerotic effects of vitamin E-myth or reality?J Cell Mol Med8597615090261
   PubMed Web of Science ®Google Scholar
• MurakamiKKondoTKawaswY1998Mitochondrial susceptibility to oxidative stress exacerbates cerebral infarction that follows permanent focal cerebral ischemia in mutant mice with manganese superoxide dismutase deficiencyJ Neurosci18205139412501
   PubMed Web of Science ®Google Scholar
• MurphyKJChronopoulosAKSinghI2003Dietary flavonoids and procyanindin oligomers from cocoa (Theobroma cacao) inhibit platelet functionAm J Clin Nutr7714667312791625
   PubMed Web of Science ®Google Scholar
• NakamuraHNakamuraKYodoiJ1997Redox regulation of cellular activationAnn Rev Immunol15351699143692
   PubMed Web of Science ®Google Scholar
• NascimentoMMSulimanMEMurayamaY2006Effect of high-dose thiamine and pyridoxine on advanced glycation end products and other oxidative stress markers in hemodialysis patients: a randomized placebo-controlled studyJ Ren Nutr161192416567267
   PubMed Web of Science ®Google Scholar
• Navari-IzzoFQuartacciMFSgherriC2002Lipoic acid: a unique anti-oxidant in the detoxification of activated oxygen speciesPlant Physiol Biochem4046370
   Web of Science ®Google Scholar
• NazirogluMButterworthP2005Protective effects of moderate exercise with dietary vitamin C and E on blood antioxidative defense mechanism in rats with streptozotocin-induced diabetesCan J Appl Physiol301728515981786
   PubMedGoogle Scholar
• NeriSSignorelliSSTorrisiB2005Effects of antioxidant supplementation on postprandial oxidative stress and endothelial dysfunction: a single-blind, 15-day clinical trial in patients with untreated type 2 diabetes, subjects with impaired glucose tolerance, and healthy controlsClin Therapeut27176473
   PubMed Web of Science ®Google Scholar
• OberleyLW1998Role of antioxidant enzymes in cell immortalization and transformationMol Cell Biochem84147533068520
   PubMed Web of Science ®Google Scholar
• OkenBSStorzbachDMKayeJA1998The efficacy of Ginkgo biloba on cognitive function in Alzheimer’s diseaseArch Neurol551409159823823
   PubMed Web of Science ®Google Scholar
• OmoniAOAlukoRE2005The anti-carcinogenic and anti-atherogenic effects of lycopene: a reviewTrends Food Sci Tech1634450
   Web of Science ®Google Scholar
• OsawaTKatoY2005Protective role of antioxidative food factors in oxidative stress caused by hyperglycemiaAnn NY Acad Sci10434405116037265
   PubMed Web of Science ®Google Scholar
• PackerLKraemerKRimbachG2001Molecular aspects of lipoic acid in the prevention of diabetes complicationsNutrition178889511684397
   PubMed Web of Science ®Google Scholar
• PalomakiAMalminiemiKMalminiemiO1999Effects of lovastatin therapy on susceptibility of LDL to oxidation during ∝-tocopherol supplementationAterioscler Thromb Vasc Biol1915418
   PubMed Web of Science ®Google Scholar
• PalozzaPSeriniSDi NicuoloF2003Prooxidant effects of β-carotene in cultured cellsMol Aspect Med2435362
   PubMed Web of Science ®Google Scholar
• PeelNMMcClureRJBartlettHP2005Behavioral determinants of healthy agingAm J Prevent Med28298304
   PubMed Web of Science ®Google Scholar
• PenckoferSSchwertzDFlorczakK2002Oxidative stress and cardiovascular disease in type 2 diabetes: the role of antioxidants and prooxidantsJ Cardiovasc Nurs16688511800069
   PubMedGoogle Scholar
• PeyserCEFolsteinMChaseGA1995Trial of α-tocopherol in Huntington’s diseaseAm J Psych15217715
   PubMed Web of Science ®Google Scholar
• PiantadosiCAZhangJ1996Mitochondrial generation of reactive oxygen species after brain ischemia in the ratStroke27327328571432
   PubMed Web of Science ®Google Scholar
• PoggioliSHilaireBFriguetB2002Age-related increase of proteins glycation in peripheral blood lymphocytes is restricted to preferential target proteinsExp Geront37120715
   Web of Science ®Google Scholar
• PoliGLeonarduzziGBiasiF2004Oxidative stress and cell signalingCurr Med Chem1111638215134513
   PubMed Web of Science ®Google Scholar
• PryorWA2000Vitamin E and heart disease: basic science to clinical intervention trialsFree Rad Biol Med281416410656300
   PubMed Web of Science ®Google Scholar
• PuntaruloS2005Iron, oxidative stress and human healthMol Aspects Med2629931216102805
   PubMedGoogle Scholar
• RahimiRNikfarSLarijaniB2005A review on the role of antioxidants in the management of diabetes and its complicationsBiomed Pharmacothe5936573
   PubMed Web of Science ®Google Scholar
• RahmanK2003Garlic and aging: new insights into an old remedyAgeing Res Rev2395612437995
   PubMed Web of Science ®Google Scholar
• RaymanMP2005Selenium in cancer prevention: a review of the evidence and mechanism of actionProc Nutr Soc645274216313696
   PubMed Web of Science ®Google Scholar
• Rice-EvansC2001Flavonoid antioxidantsCurr Med Chem879780711375750
   PubMed Web of Science ®Google Scholar
• Rice-EvansCASampsonJBramleyPM1997Why do we expect carotenoids to be antioxidants in vivo?Free Rad Res2638198
   PubMed Web of Science ®Google Scholar
• RileyPA1994Free radicals in biology: oxidative stress and effects of ionizing radiationInt J Rad Biol6527337905906
   PubMed Web of Science ®Google Scholar
• RostanEFDeBuysHVMadeyDL2002Evidence supporting zinc as an important antioxidant for skinIntern J Dermatol4160611
   PubMed Web of Science ®Google Scholar
• RuelGPomerleauSCoutureP2005Changes in plasma antioxidant capacity and oxidized low-density lipoprotein levels in men after short-term cranberry juice consumptionMetabolism548566115988692
   PubMed Web of Science ®Google Scholar
• RuhnauKJMeissnerHPFinnJR1999Effects of a 3-week oral treatment with the antioxidant thiotic acid (a-lipoic acid) in symptomatic diabetic polyneuropathyDiabet Med161040310656234
   PubMed Web of Science ®Google Scholar
• SammanSSivarajahGManJC2003A mixed fruit and vegetable concentrate increases plasma antioxidant vitamins and folate and lowers plasma homocysteine in menJ Nutr13321889312840177
   PubMed Web of Science ®Google Scholar
• Sánchez-MorenoCCanoMPBegoña deA2006Mediterranean vegetable soup consumption increases vitamin C and decreases F2-isoprostanes, prostaglandin E2, and monocyte chemotactic protein-1 in healthy humansJ Nutr Biochem17183916169205
   PubMed Web of Science ®Google Scholar
• Santos-BuelgaCScalbertA2000Proanthocyanidins and tannin-like compounds in human nutritionJ Food Sci Agr801094117
   Web of Science ®Google Scholar
• SarkarFHLiY2004Cell signaling pathways altered by natural chemo-preventative agentsMutat Res555536415476851
   PubMed Web of Science ®Google Scholar
• SavithaSPanneerselvamC2006Mitochondrial membrane damage during aging process in rat heart: potential efficacy of L-carnitine and DL alpha lipoic acidMech Ageing Dev1273495516430943
   PubMed Web of Science ®Google Scholar
• SchachingerVZeiherAM2002Atherogenesis-recent insights into basic mechanisms and their clinical impactNephrol Dial Transplant1720556412454211
   PubMed Web of Science ®Google Scholar
• SchipplingSKontushAArltS2000Increased lipoprotein oxidation in Alzheimer’s diseaseFree Rad Biol Med283516010699746
   PubMed Web of Science ®Google Scholar
• SchneiderLSDeKoskySTFarlowMR2005A randomized, double-blind, placebo-controlled trial of two doses of Ginkgo biloba extract in dementia of the Alzheimer’s typeCurr Alzheimer Res25415116375657
   PubMedGoogle Scholar
• SchrauzerGN2000Anticarcinogenic effects of seleniumCell Mol Life Sci5718647311215513
   PubMed Web of Science ®Google Scholar
• SchroeterHBoydCSpencerJPE2002MAPK signaling in neurodegeneration: influences of flavonoids and of nitric acidNeurobiol Aging238618012392791
   PubMed Web of Science ®Google Scholar
• ScottJ2004Pathophysiology and biochemistry of cardiovascular diseaseCurr Opion Genet Develop142719
   PubMed Web of Science ®Google Scholar
• SechiGDeedenMGBuaG1996Reduced intravenous glutathione in the treatment of early Patkinson’s diseaseProgress Neuropsychopharmacol Biol Psych20115970
   PubMed Web of Science ®Google Scholar
• SelkoeDJ2004Alzheimer disease: mechanistic understanding predicts novel therapiesAnn Intern Med1406273815096334
   PubMed Web of Science ®Google Scholar
• Serra-MajemLRomanBEstruchR2006Scientific evidence of interventions using the Mediterranean diet: A systematic reviewNutr Rev64S27S4716532897
   PubMed Web of Science ®Google Scholar
• ShiHHudsonLGLiuKJ2004Oxidative stress and apoptosis in metal ion-induced carcinogenesis. 2004Free Rad Biol Med375829315288116
   PubMed Web of Science ®Google Scholar
• Shukitt-HaleBCareyALauraSBA2006Effects of Concord grape juice on cognitive and motor deficits in agingNutrition2229530216412610
   PubMed Web of Science ®Google Scholar
• SiesHStahlWSevanianA2005Nutritional, dietary and post-prandial oxidative stressJ Nutr1359697215867266
   PubMed Web of Science ®Google Scholar
• SimmsNRAndersonMF2002Mitochondrial contributions to tissue damage in strokeNeurochem Int405112611850108
   PubMed Web of Science ®Google Scholar
• SingletonCKMartinPR2001Molecular mechanisms of thiamine utilizationCurr Mol Med119720711899071
   PubMedGoogle Scholar
• SmithARShenviSVWidlanskyM2004Lipoic acid as a potential therapy for chronic diseases associated with oxidative stressCurr Med Chem1111354615134511
   PubMed Web of Science ®Google Scholar
• SohalRSMockettRJOrrWC2002Mechanisms of Aging: An appraisal of the oxidative stress hypothesisFree Rad Biol Med335758612208343
   PubMed Web of Science ®Google Scholar
• SohalRSWeindruchR1996Oxidative stress, caloric restriction, and ageingScience27359638658196
   PubMed Web of Science ®Google Scholar
• SongKLeeWJKohJ2004α-Lipoic acid prevents diabetes mellitus in diabetes-prone obese ratsBiochem Biophys Res Comm32619720215567171
   PubMed Web of Science ®Google Scholar
• SongYQMansonJEBuringJE2005Association of dietary flavonoids with risk of type 2 diabetes, and markers of insulin resistance and systemic inflammation in women: a prospective study and cross-sectional analysisJ Am Coll Nutr243768416192263
   PubMed Web of Science ®Google Scholar
• StahlWSiesH2003Antioxidant activity of carotenoidsMol Aspect Med2434551
   PubMed Web of Science ®Google Scholar
• SutherlandBARahmanRMAAppletonI2006Mechanisms of action of green tea catechins, with a focus on ischemia-induced neurodegenerationJ Nutr Biochem1729130616443357
   PubMed Web of Science ®Google Scholar
• TapiaLGonzalez-AgueroMCisternasMF2004Metallothionein is crucial for safe intracellular copper storage and cell survival at normal and supra-physiological exposure levelsBiochem37861724
   Web of Science ®Google Scholar
• TapieroHTownsendDMTewKD2004The role of carotenoids in the prevention of human pathologiesBiomed Pharmacother581001014992791
   PubMed Web of Science ®Google Scholar
• TroncosoJCCostelloAWatsonAL1993In vitro polymerization of oxidized tau into filamentsBrain Res61331368186983
   PubMed Web of Science ®Google Scholar
• TruebaGPSanchezGMGiulianiA2004Oxygen free radical and antioxidant defense mechanism in cancerFront Biosci920294415353268
   PubMed Web of Science ®Google Scholar
• TuckerJMTownsendDM2005Alpha-tocopherol: roles in prevention and therapy of human diseaseBiomed Pharmacother59380716081238
   PubMed Web of Science ®Google Scholar
• TurnlundJRScottKCPeifferGL1997Copper status of young men consuming a low-copper dietAm J Clin Nutr657288988916
   PubMed Web of Science ®Google Scholar
• TurunenMOlssonJDallnerG2004Metabolism and function of coenzyme QBiochim Biophys Acta16601719914757233
   PubMed Web of Science ®Google Scholar
• UpritchardJESutherlandWHMannJL2000Effect of supplementation with tomato juice, Vitamins E and C on LDL oxidation and products of inflammatory activity in type 2 diabetesDiab Care237338
   PubMed Web of Science ®Google Scholar
• Uriu-AdamsJYKeenCL2005Copper, oxidative stress, and human healthMol Aspects Med262689816112185
   PubMedGoogle Scholar
• Uriu-AdamsJYRuckerRBCommissoJF2005Diabetes and dietary copper alter Cu metabolism and oxidant defense in the ratJ Nutr Biochem163122015866232
   PubMed Web of Science ®Google Scholar
• ValkoMIzakovicMMazurM2004Role of oxygen radicals in DNA damage and cancer incidenceCell Biochem2663756
   Web of Science ®Google Scholar
• ValkoMMorrisHCronninMTD2005Metals, toxicity and oxidative stressCurr Med Chem12116120815892631
   PubMed Web of Science ®Google Scholar
• ValkoMRhodesCJMoncolJ2006Free radicals, metals and antioxidants in oxidative stress-induced cancerChemico-Biol Inter160140
   PubMed Web of Science ®Google Scholar
• Van DongenMVan RossumEKesselsA2000The efficacy of gingko for elderly people with dementia and age-associated memory impairment: new results of a randomized clinical trialJ Am Geriatr Soc4811839411037003
   PubMed Web of Science ®Google Scholar
• VarmaMPaneriSBadiP2005Status of MDA and antioxidant enzymes in hyperglycemic postmenopausal womenFlora and Fauna (Jhansi)111015
   Google Scholar
• VitsevaOVargheseSChakrabartiS2005Grape seed and skin inhibit platelet function and release of reactive oxygen intermediatesJ Cardiovasc Pharmacol464455116160595
   PubMed Web of Science ®Google Scholar
• VölkelWSiciliaTPählerA2006Increased brain levels of 4-hydroxy-2-nonenal glutathione conjugates in severe Alzheimer’s diseaseNeurochem Intern48679686
   Web of Science ®Google Scholar
• WautierJLSchmidtAM2004Protein glycationCirculation Res95233815297385
   PubMed Web of Science ®Google Scholar
• WeiZLauBHS1998Garlic inhibits free radical generation and augments antioxidant enzyme activity in vascular endothelial cellsNutr Res186170
   Web of Science ®Google Scholar
• WersingerCSidhuA2002Inflammation and Parkinson’s diseaseCurr Drug Targets Inflamm Allergy12214214561187
   PubMedGoogle Scholar
• WidlanskyMEDuffySJHamburgNM2005Effects of black tea consumption on plasma catechins and markers of oxidative stress and inflammation in patients with coronary artery diseaseFree Rad Biol Med3849950615649652
   PubMed Web of Science ®Google Scholar
• WillettWC2006The Mediterranean diet: science and practicePublic Health Nutr91051016512956
   PubMed Web of Science ®Google Scholar
• World Health OrganizationKeeping fit for life: meeting the nutritional needs of older personsGeneva, SwitzerlandWHO2002
   Google Scholar
• WrightEjrScism-BaconJLGlassLC2006Oxidative stress in type 2 diabetes: the role of fasting and postprandial glycemiaInt J Clin Prac6030814
   PubMed Web of Science ®Google Scholar
• YehC-CHouM-FTsaiS-M2005Superoxide anion radical, lipid peroxides and antioxidant status in the blood of patients with breast cancerClin Chim Acta3611041116009358
   PubMed Web of Science ®Google Scholar
• YochumLKushiLHMeyerK1999Dietary flavonoid intake and risk of cardiovascular disease in postmenopausal womenAm J Epidemiol149943910342803
   PubMed Web of Science ®Google Scholar
• YouWCZhangLGailMH2000Gastric dysplasia and gastric cancer: Helicobacter pylori, serum Vitamin C, and other risk factorsJ Natl Cancer Inst9216071211018097
   PubMed Web of Science ®Google Scholar
• YoudimKAJosephJA2001A possible emerging role of phytochemicals in improving age-related neurological dysfunctions: a multiplicity of effectsFree Rad Biol Med305839411295356
   PubMed Web of Science ®Google Scholar