Adipose inflammation: cause or consequence of obesity-related insulin resistance

References

• ArkanMCHevenerALGretenFR2005IKK-beta links inflammation to obesity-induced insulin resistanceNat Med11191815685170
   PubMed Web of Science ®Google Scholar
• BluherMMichaelMDPeroniOD2002Adipose tissue selective insulin receptor knockout protects against obesity and obesity-related glucose intoleranceDev Cell3253812110165
   PubMed Web of Science ®Google Scholar
• BouhlelMADerudasBRigamontiE2007PPARgamma activation primes human monocytes into alternative M2 macrophages with anti-inflammatory propertiesCell Metab61374317681149
   PubMed Web of Science ®Google Scholar
• CaiDYuanMFrantzDF2005Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaBNat Med111839015685173
   PubMed Web of Science ®Google Scholar
• CancelloRHenegarCViguerieN2005Reduction of macrophage infiltration and chemoattractant gene expression changes in white adipose tissue of morbidly obese subjects after surgery-induced weight lossDiabetes5422778616046292
   PubMed Web of Science ®Google Scholar
• CancelloRTordjmanJPoitouC2006Increased infiltration of macrophages in omental adipose tissue is associated with marked hepatic lesions in morbid human obesityDiabetes5515546116731817
   PubMed Web of Science ®Google Scholar
• CharriereGCousinBArnaudE2003Preadipocyte conversion to macrophage. Evidence of plasticityJ Biol Chem2789850512519759
   PubMed Web of Science ®Google Scholar
• CintiSMitchellGBarbatelliG2005Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humansJ Lipid Res4623475516150820
   PubMed Web of Science ®Google Scholar
• ClementKViguerieNPoitouC2004Weight loss regulates inflammation-related genes in white adipose tissue of obese subjectsFASEB J1816576915522911
   PubMed Web of Science ®Google Scholar
• CousinBMunozOAndreM1999A role for preadipocytes as macrophage-like cellsFASEB J13305129973318
   PubMed Web of Science ®Google Scholar
• CrookMATuttPSimpsonH1993Serum sialic acid and acute phase proteins in type 1 and type 2 diabetes mellitusClin Chim Acta21913187508342
   PubMed Web of Science ®Google Scholar
• Di GregorioGBYao-BorengasserARasouliN2005Expression of CD68 and macrophage chemoattractant protein-1 genes in human adipose and muscle tissues: association with cytokine expression, insulin resistance, and reduction by pioglitazoneDiabetes5423051316046295
   PubMed Web of Science ®Google Scholar
• Elgazar-CarmonVRudichAHadadN2008Neutrophils transiently infiltrate intra-abdominal fat early in the course of high fat feedingJ Lipid Res49189490318503031
   PubMed Web of Science ®Google Scholar
• FearnleyGRVincentCTChakrabartiR1959Reduction of blood fibrinolytic activity in diabetes mellitus by insulinLancet2106713821819
   PubMed Web of Science ®Google Scholar
• FeinsteinRKanetyHPapaMZ1993Tumor necrosis factor-alpha suppresses insulin-induced tyrosine phosphorylation of insulin receptor and its substratesJ Biol Chem2682605588253716
   PubMed Web of Science ®Google Scholar
• FestaAD’AgostinoRJrTracyRP2002Elevated levels of acute-phase proteins and plasminogen activator inhibitor-1 predict the development of type 2 diabetes: the insulin resistance atherosclerosis studyDiabetes511131711916936
   PubMed Web of Science ®Google Scholar
• GanrotPOGydellKEkelundH1967Serum concentration of alpha-2-macroglobulin, haptoglobin and alpha-1-antitrypsin in diabetes mellitusActa Endocrinol (Copenh)55537444166389
   PubMedGoogle Scholar
• GerhardtCCRomeroIACancelloR2001Chemokines control fat accumulation and leptin secretion by cultured human adipocytesMol Cell Endocrinol175819211325518
   PubMed Web of Science ®Google Scholar
• GhanimHAljadaAHofmeyerD2004Circulating mononuclear cells in the obese are in a proinflammatory stateCirculation11015647115364812
   PubMed Web of Science ®Google Scholar
• GhanimHDhindsaSAljadaA2006Low-dose rosiglitazone exerts an antiinflammatory effect with an increase in adiponectin independently of free fatty acid fall and insulin sensitization in obese type 2 diabeticsJ Clin Endocrinol Metab913553816804037
   PubMed Web of Science ®Google Scholar
• GhanimHGargRAljadaA2001Suppression of nuclear factor-kappaB and stimulation of inhibitor kappaB by troglitazone: evidence for an anti-inflammatory effect and a potential antiatherosclerotic effect in the obeseJ Clin Endocrinol Metab8613061211238525
   PubMed Web of Science ®Google Scholar
• GreenADobiasSBWaltersDJ1994Tumor necrosis factor increases the rate of lipolysis in primary cultures of adipocytes without altering levels of hormone-sensitive lipaseEndocrinology134258188194485
   PubMed Web of Science ®Google Scholar
• Harman-BoehmIBluherMRedelH2007Macrophage infiltration into omental versus subcutaneous fat across different populations: effect of regional adiposity and the comorbidities of obesityJ Clin Endocrinol Metab922240717374712
   PubMed Web of Science ®Google Scholar
• HechtAGoldnerMG1959Reappraisal of the hypoglycemic action of acetylsalicylateMetabolism84182813666386
   PubMed Web of Science ®Google Scholar
• HevenerALOlefskyJMReichartD2007Macrophage PPAR gamma is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinedionesJ Clin Invest11716586917525798
   PubMed Web of Science ®Google Scholar
• HillJOWyattHRReedGW2003Obesity and the environment: where do we go from here?Science299853512574618
   PubMed Web of Science ®Google Scholar
• HirosumiJTuncmanGChangL2002A central role for JNK in obesity and insulin resistanceNature420333612447443
   PubMed Web of Science ®Google Scholar
• HotamisligilGSArnerPCaroJF1995Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistanceJ Clin Invest952409157738205
   PubMed Web of Science ®Google Scholar
• HotamisligilGSBudavariAMurrayD1994Reduced tyrosine kinase activity of the insulin receptor in obesity-diabetes. Central role of tumor necrosis factor-alphaJ Clin Invest94154397523453
   PubMed Web of Science ®Google Scholar
• HotamisligilGSShargillNSSpiegelmanBM1993Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistanceScience25987917678183
   PubMed Web of Science ®Google Scholar
• InouyeKEShiHHowardJK2007Absence of CC chemokine ligand 2 does not limit obesity-associated infiltration of macrophages into adipose tissueDiabetes5622425017473219
   PubMed Web of Science ®Google Scholar
• KameiNTobeKSuzukiR2006Overexpression of monocyte che-moattractant protein-1 in adipose tissues causes macrophage recruitment and insulin resistanceJ Biol Chem281266021416809344
   PubMed Web of Science ®Google Scholar
• KandaHTateyaSTamoriY2006MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesityJ Clin Invest116149450516691291
   PubMed Web of Science ®Google Scholar
• KopelmanPG2000Obesity as a medical problemNature4046354310766250
   PubMed Web of Science ®Google Scholar
• LeeJYSohnKHRheeSH2001Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4J Biol Chem27616683911278967
   PubMed Web of Science ®Google Scholar
• LiACBrownKKSilvestreMJ2000Peroxisome proliferator-activated receptor gamma ligands inhibit development of atherosclerosis in LDL receptor-deficient miceJ Clin Invest1065233110953027
   PubMed Web of Science ®Google Scholar
• LumengCNBodzinJLSaltielAR2007Obesity induces a phenotypic switch in adipose tissue macrophage polarizationJ Clin Invest1171758417200717
   PubMed Web of Science ®Google Scholar
• MedzhitovRPreston-HurlburtPJanewayCAJr1997A human homologue of the Drosophila Toll protein signals activation of adaptive immunityNature38839479237759
   PubMed Web of Science ®Google Scholar
• MohantyPAljadaAGhanimH2004Evidence for a potent antiinflammatory effect of rosiglitazoneJ Clin Endocrinol Metab8927283515181049
   PubMed Web of Science ®Google Scholar
• MorimotoYNishikawaKOhashiM1997KB-R7785, a novel matrix metalloproteinase inhibitor, exerts its antidiabetic effect by inhibiting tumor necrosis factor-alpha productionLife Sci617958039275009
   PubMed Web of Science ®Google Scholar
• OdegaardJIRicardo-GonzalezRRGoforthMH2007Macrophage-specific PPARgamma controls alternative activation and improves insulin resistanceNature44711162017515919
   PubMed Web of Science ®Google Scholar
• OgstonDMcAndrewGM1964Fibrinolysis in obesityLancet21205714215560
   PubMed Web of Science ®Google Scholar
• OhmanMKShenYObimbaCI2008Visceral adipose tissue inflammation accelerates atherosclerosis in apolipoprotein E-deficient miceCirculation11779880518212290
   PubMed Web of Science ®Google Scholar
• PickupJCMattockMBChusneyGD1997NIDDM as a disease of the innate immune system: association of acute-phase reactants and interleukin-6 with metabolic syndrome XDiabetologia401286929389420
   PubMed Web of Science ®Google Scholar
• PoltorakAHeXSmirnovaI1998Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 geneScience282208589851930
   PubMed Web of Science ®Google Scholar
• PradhanADMansonJERifaiN2001C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitusJAMA2863273411466099
   PubMed Web of Science ®Google Scholar
• ReidJMacDougallAIAndrewsMM1957Aspirin and diabetes mellitusBr Med J21071413472052
   PubMed Web of Science ®Google Scholar
• RotterVNagaevISmithU2003Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and tumor necrosis factor-alpha, overexpressed in human fat cells from insulin-resistant subjectsJ Biol Chem278457778412952969
   PubMed Web of Science ®Google Scholar
• SartipyPLoskutoffDJ2003Monocyte chemoattractant protein 1 in obesity and insulin resistanceProc Natl Acad Sci U S A10072657012756299
   PubMed Web of Science ®Google Scholar
• SchreyerSAChuaSCJrLeBoeufRC1998Obesity and diabetes in TNF-alpha receptor- deficient miceJ Clin Invest102402119664082
   PubMed Web of Science ®Google Scholar
• ShiHKokoevaMVInouyeK2006TLR4 links innate immunity and fatty acid-induced insulin resistanceJ Clin Invest11630152517053832
   PubMed Web of Science ®Google Scholar
• StojanovskaLHonisettSYKomesaroffPA2007The anti-atherogenic effects of thiazolidinedionesCurr Diabetes Rev3677418220657
   PubMedGoogle Scholar
• StrisselKJStanchevaZMiyoshiH2007Adipocyte death, adipose tissue remodeling, and obesity complicationsDiabetes562910817848624
   PubMed Web of Science ®Google Scholar
• TsukumoDMCarvalho-FilhoMACarvalheiraJB2007Loss-of-function mutation in Toll-like receptor 4 prevents diet-induced obesity and insulin resistanceDiabetes5619869817519423
   PubMed Web of Science ®Google Scholar
• UysalKTWiesbrockSMHotamisligilGS1998Functional analysis of tumor necrosis factor (TNF) receptors in TNF-alpha-mediated insulin resistance in genetic obesityEndocrinology139483289832419
   PubMed Web of Science ®Google Scholar
• UysalKTWiesbrockSMMarinoMW1997Protection from obesity-induced insulin resistance in mice lacking TNF-alpha functionNature38961049335502
   PubMed Web of Science ®Google Scholar
• VentreJDoebberTWuM1997Targeted disruption of the tumor necrosis factor-alpha gene: metabolic consequences in obese and non-obese miceDiabetes461526319287059
   PubMed Web of Science ®Google Scholar
• VozarovaBWeyerCLindsayRS2002High white blood cell count is associated with a worsening of insulin sensitivity and predicts the development of type 2 diabetesDiabetes514556111812755
   PubMed Web of Science ®Google Scholar
• WeisbergSPHunterDHuberR2006CCR2 modulates inflammatory and metabolic effects of high-fat feedingJ Clin Invest1161152416341265
   PubMed Web of Science ®Google Scholar
• WeisbergSPMcCannDDesaiM2003Obesity is associated with macrophage accumulation in adipose tissueJ Clin Invest112179680814679176
   PubMed Web of Science ®Google Scholar
• WilliamsonRT1901On the treatment of glycosuria and diabetes mellitus with sodium salicylateBr Med J1760220759517
   PubMedGoogle Scholar
• XuHBarnesGTYangQ2003Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistanceJ Clin Invest11218213014679177
   PubMed Web of Science ®Google Scholar
• XuHHirosumiJUysalKT2002aExclusive action of transmembrane TNF alpha in adipose tissue leads to reduced adipose mass and local but not systemic insulin resistanceEndocrinology14315021111897709
   PubMed Web of Science ®Google Scholar
• XuHHotamisligilGS2001Signaling pathways utilized by tumor necrosis factor receptor 1 in adipocytes to suppress differentiationFEBS Lett5069710211591379
   PubMed Web of Science ®Google Scholar
• XuHSethiJKHotamisligilGS1999Transmembrane tumor necrosis factor (TNF)-alpha inhibits adipocyte differentiation by selectively activating TNF receptor 1J Biol Chem274262879510473584
   PubMed Web of Science ®Google Scholar
• XuHUysalKTBechererJD2002bAltered tumor necrosis factor-alpha (TNF-alpha) processing in adipocytes and increased expression of transmembrane TNF-alpha in obesityDiabetes5118768312031976
   PubMed Web of Science ®Google Scholar
• YuanMKonstantopoulosNLeeJ2001Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of IkkbetaScience2931673711533494
   PubMed Web of Science ®Google Scholar