Synergistic potentiation of D-fraction with vitamin C as possible alternative approach for cancer therapy

References

• ShirotaMWhat do you know about medicinal mushroomsExplore199674852
   Google Scholar
• WasserSPNevoESokolovDReshetnikovSTimor-TismenetskyMDietary supplements from medicinal mushrooms: diversity of types and variety of regulationsInt J Med Mushr20002119
   Google Scholar
• MizunoTZhuangCMaitake, Grifola frondosa: pharmacological effectsFood Rev Int199511135149
   Google Scholar
• ManoharVTalpurNAEchardBWLiebermanSPreussHGEffects of a water-soluble extract of maitake mushroom on circulating glucose/insulin concentrations in KK miceDiabetes Obes Metab20024434811874441
   PubMed Web of Science ®Google Scholar
• KuboKAokiHNanbaHAnti-diabetic activity present in the fruit body of Grifola frondosa (maitake)Biol Pharm Bull199417110611107820117
   PubMed Web of Science ®Google Scholar
• KuboKNanbaHThe effect of maitake mushrooms on liver and serum lipidsAltern Ther Health Med1996262668795938
   PubMedGoogle Scholar
• JonesKMaitake, a potent medicinal foodAltern Complement Ther19984420429
   Google Scholar
• KabirYYamaguchiMKimuraSEffect of shiitake (Lentinus edodes) and maitake (Grifola frondosa) mushrooms on blood pressure and plasma lipids of spontaneously hypertensive ratsJ Nutr Sci Vitaminol (Tokyo)1987333413463443885
   PubMed Web of Science ®Google Scholar
• AdachiKNanbaHOtsukaMKurodaHBlood pressure-lowering activity present in the fruit body of Grifola frondosaChem Pharm Bull198836100010063409391
   PubMed Web of Science ®Google Scholar
• NakaiRMasuiHHorioHOhtsuruMEffect of maitake (Grifola frondosa) water extract on inhibition of adipocyte conversion of C3H10T1/2B2C1 cellsJ Nutr Sci Vitaminol (Tokyo)19994538538910524358
   PubMed Web of Science ®Google Scholar
• GuCQLiJWChaoFHInhibition of hepatitis B virus by D-fraction from Grifola frondosa: synergistic effect of combination with interferon-α in HepG2 2.2.15Antiviral Res20067216216516846649
   PubMed Web of Science ®Google Scholar
• Developmental Therapeutics Program, National Cancer InstituteIn-vitro anti-HIV drug screening resultsNSCF19500111992
   Google Scholar
• NanbaHHamaguchiAKurodaHThe chemical structure of an antitumor polysaccharide in fruit bodies of Grifola frondosa (maitake)Chem Pharm Bull198735116211683607939
   PubMed Web of Science ®Google Scholar
• WasserSPMedicinal mushrooms as a source of antitumor and immunomodulating polysaccharidesAppl Microbiol Biotechnol20026025827412436306
   PubMed Web of Science ®Google Scholar
• LullCWichersHJSavelkoulHFAntiinflammatory and immunomodulating properties of fungal metabolitesMediators Inflamm20052638016030389
   PubMed Web of Science ®Google Scholar
• WilliamsDLMuellerABrowderWGlucan-based macrophage stimulatorsClin Immunother19965392399
   Google Scholar
• BrownGDGordonSFungal beta-glucans and mammalian immunityImmunity20031931131514499107
   PubMed Web of Science ®Google Scholar
• BrownGDGordonSImmune recognition of fungal β-glucansCell Microbiol2005747147915760447
   PubMed Web of Science ®Google Scholar
• TaylorPRBrownGDReidDMThe beta-glucan receptor, Dectin-1, is predominantly expressed on the surface of cells of the monocyte/macrophage and neutrophil lineagesJ Immunol20022693876388212244185
   PubMed Web of Science ®Google Scholar
• BrownGDHerreJWilliamsDLWillmentJAMarshallASGordonSDectin-1 mediates the biological effects of beta-glucanJ Exp Med20031971119112412719478
   PubMed Web of Science ®Google Scholar
• LinHSheYHCassilethBRSirotnakFCunningham RundlesSMaitake beta-glucan MD-fraction enhances bone marrow colony formation and reduces doxorubicin toxicity in vitroInt Immunopharmacol20044919914975363
   PubMed Web of Science ®Google Scholar
• LinHCheungSWYNesinMCassilethBRCunningham RundlesSEnhancement of umbilical cord blood cell hematopoiesis by maitake beta-glucan is mediated by granulocyte colony-stimulating factor productionClin Vaccine Immunol200714212717093103
   PubMed Web of Science ®Google Scholar
• de ChastellierCBerchePFate of Listeria monocytogenes in murine macrophages: evidence for simultaneous killing and survival of intra-cellular bacteriaInfect Immun1994625435538300212
   PubMed Web of Science ®Google Scholar
• KodamaNYamadaMNanbaHAddition of maitake D-fraction reduces the effective dosage of vancomycin for the treatment of Listeria-infected miceJpn J Pharmacol20018732733211829152
   PubMedGoogle Scholar
• SanzenIImanishiNTakamatsuNNitric oxide-mediated anti-tumor activity induced by the extract from Grifola frondosa (Maitake mushroom) in a macrophage cell line, RAW264.7J Exp Clin Cancer Res20012059159711876556
   PubMed Web of Science ®Google Scholar
• NanbaHMaitake D-fraction: healing and preventive potential for cancerJ Orthomol Med1997124349
   Google Scholar
• MillerJSBiology of natural killer cells in cancer and infectionCancer Invest20022040541912025235
   PubMed Web of Science ®Google Scholar
• SepulvedaCPuenteJNatural killer cells and the innate immune system in infectious pathologyRev Med Chil20001281361137011227246
   PubMed Web of Science ®Google Scholar
• KodamaNKomutaKSakaiNNanbaHEffects of D-fraction, a polysaccharide from Grifola frondosa, on tumor growth involve activation of NK cellsBiol Pharm Bull2002251647165012499658
   PubMed Web of Science ®Google Scholar
• KodamaNKomutaKNanbaHEffect of Maitake (Grifola frondosa) D-fraction on the activation of NK cells in cancer patientsJ Med Food2003637137714977447
   PubMedGoogle Scholar
• KodamaNMurataYNanbaHAdministration of a polysaccharide from Grifola frondosa stimulates immune function of normal miceJ Med Food2004714114515298759
   PubMed Web of Science ®Google Scholar
• MosmannTRSadSThe expanding universe of T-cell subsets: Th1, Th2 and moreImmunol Today1996171381468820272
   PubMedGoogle Scholar
• InoueAKodamaNNanbaHEffect of Maitake (Grifola frondosa) D-fraction on the control of the T lymph node Th-1/Th-2 proportionBiol Pharm Bull20022553654011995941
   PubMed Web of Science ®Google Scholar
• KodamaNHaradaNNanbaHA polysaccharide, extract from Grifola frondosa, induces Th-1 dominant responses in carcinoma-bearing BALB/c miceJpn J Pharmacol20029035736012501013
   PubMedGoogle Scholar
• HaradaNKodamaNNanbaHRelationship between dendritic cells and the D-fraction-induced Th-1 dominant response in BALB/c tumor-bearing miceCancer Lett200319218118712668282
   PubMed Web of Science ®Google Scholar
• DengGLinHSeidmanAA phase I/II trial of a polysaccharide extract from Grifola frondosa (Maitake mushroom) in breast cancer patients: immunological effectsJ Cancer Res Clin Oncol200931 [Epub ahead of print]
   Web of Science ®Google Scholar
• GlaucoSJanoFPaoloGKonnoSSafety of maitake D-fraction in healthy patients: assessment of common hematologic parametersAltern Complement Ther200410228230
   Google Scholar
• OhnoNIinoKTakeyamaTStructural characterization and antitumor activity of the extracts from matted mycelium of cultured Grifola frondosaChem Pharm Bull198533339534014085071
   PubMed Web of Science ®Google Scholar
• NanbaHAntitumor activity of orally administered D-fraction from maitake mushroomJ Naturopathic Med199341015
   Google Scholar
• NanbaHActivity of Maitake D-fraction to inhibit carcinogenesis and metastasisAnn N Y Acad Sci19957682432458526356
   PubMed Web of Science ®Google Scholar
• NanbaHEffect of Maitake D-fraction on cancer preventionAnn N Y Acad Sci19978332042079616756
   PubMed Web of Science ®Google Scholar
• NanbaHResults of non-controlled clinical study for various cancer patients using Maitake D-fractionExplore199561921
   Google Scholar
• Maitake Products IncMaitake D-fraction obtained IND for clinical studyParamus, NJMaitake Products, Inc21998
   Google Scholar
• KonnoSMaitake D-fraction: a potent mushroom extract product against human malignanciesTownsend Lett200223396100
   Google Scholar
• GleasonDFMellingerGTPrediction of prognosis for prostatic adenocarcinoma by combined histological grading and clinical stagingJ Urol197411158644813554
   PubMed Web of Science ®Google Scholar
• CarrAFreiBDoes vitamin C act as a pro-oxidant under physiological conditions? FASEB J1999131007102410336883
   PubMed Web of Science ®Google Scholar
• BuettnerGJurkiewiczBCatalytic metals, ascorbate and free radicals: combinations to avoidRadit Res1996145532541
   PubMed Web of Science ®Google Scholar
• ClementMRamalingamJLongLHalliwellBThe in vitro cytotoxicity of ascorbate depends on the culture medium used to perform the assay and involves hydrogen peroxideAntioxid Redox Signal2001315716311291594
   PubMed Web of Science ®Google Scholar
• ChenQEspeyMSunAAscorbate in pharmacologic concentrations selectively generates ascorbate radical and hydrogen peroxide in extracellular fluid in vivoProc Natl Acad Sci U S A20071044954
   Web of Science ®Google Scholar
• ChenQEspeyMKrishnaMPharmacologic ascorbic acid concentrations selectively kill cancer cells: action as a pro-drug to deliver hydrogen peroxide to tissuesProc Natl Acad Sci U S A2005102136041360916157892
   PubMed Web of Science ®Google Scholar
• TaperHde GerlacheJLansMRoberfroidMNon-toxic potentiation of cancer chemotherapy by combined C and K3 vitamin pre-treatmentInt J Cancer1987405755793666992
   PubMed Web of Science ®Google Scholar
• PathakABhutaniMGuleriaRChemotherapy alone vs chemotherapy plus high dose multiple antioxidants in patients with advanced non-small cell lung cancerJ Am Coll Nutr200524162115670980
   PubMed Web of Science ®Google Scholar
• CreaganEMoertelCO’FallonJFailure of high-dose vitamin C (ascorbic acid) therapy to benefit patients with advanced cancer: a controlled trialN Engl J Med1979301687690384241
   PubMed Web of Science ®Google Scholar
• LevineMConry-CantilenaCWangYVitamin C pharmacokinetics in healthy volunteers: evidence for a recommended dietary allowanceProc Natl Acad Sci U S A199693370437098623000
   PubMed Web of Science ®Google Scholar
• HofferLLevineMAssoulineSPhase I clinical trial of i.v. ascorbic acid in advanced malignancyAnn Oncol2008191969197418544557
   PubMed Web of Science ®Google Scholar
• MorishigeFMeyskensFIJrParasadKNThe role of vitamin C in tumor therapy (human)Vitamins and Cancer: Human Cancer Prevention by Vitamins and MicronutrientsClifton, NJHumana Press1986399427
   Google Scholar
• FullertonSASamadiAATortorelisDGInduction of apoptosis in human prostatic cancer cells with β-glucan (maitake mushroom polysaccharide)Mol Urol2000471110851301
   PubMedGoogle Scholar
• ZerbibMZelefskyMJHiganoCSCarrollPRConventional treatments of localized prostate cancerUrology2008722535
   Web of Science ®Google Scholar
• KreisWCurrent chemotherapy and future directions in research for the treatment of advanced hormone-refractory prostate cancerCancer Invest1995132963127743383
   PubMed Web of Science ®Google Scholar
• KaighnMENarayanKSOhnukiYLechnerJFJonesLWEstablishment and characterization of a human prostate carcinoma cell line (PC-3)Invest Urol1979171623447482
   PubMedGoogle Scholar
• MalorniWIosiFMirabelliFBellomoGCytoskeleton as a target in menedione-induced oxidative stress in cultured mammalian cells: alterations underlying surface bleb formationChem Biol Interact1991802172361934151
   PubMed Web of Science ®Google Scholar
• DargelRLipid peroxidation: a common pathogenetic mechanism? Exp Toxicol Pathol1992441691811392519
   PubMed Web of Science ®Google Scholar
• De LaurenziVMelinoGSaviniIAnnicchiarico-PetruzzelliMFinazzi-AgroAAviglianoLCell death by oxidative stress and ascorbic acid regeneration in human neuroectodermal cell linesEur J Cancer199531A4634667576946
   PubMed Web of Science ®Google Scholar
• LeungPYMiyashitaKYoungMTsaoCSCytotoxic effect of ascorbate and its derivatives on cultured malignant and nonmalignant cell linesAnticancer Res1993134754808517665
   PubMed Web of Science ®Google Scholar
• SinhaBKMimnaughEGFree radicals and anticancer drug resistance: oxygen free radicals in the mechanisms of drug cytotoxicity and resistance by certain tumorsFree Radic Biol Med199085675812113883
   PubMed Web of Science ®Google Scholar
• GavrieliYShermanYBen-SassonSAIdentification of programmed cell death in situ via specific labeling of nuclear DNA fragmentationJ Cell Biol19921194935011400587
   PubMed Web of Science ®Google Scholar
• TheyerGHamiltonGRole of multidrug resistance in tumors of the genitourinary tractUrology1994449429507985331
   PubMed Web of Science ®Google Scholar
• BorchersATSternJSHackmanRMMushrooms, tumors and immunityProc Soc Exp Biol Med199922128129310460691
   PubMed Web of Science ®Google Scholar
• KonnoSPotential growth inhibitory effect of maitake D-fraction on canine cancer cellsVet Ther2004526327115719326
   PubMedGoogle Scholar