70
Views
0
CrossRef citations to date
0
Altmetric
Review

Update and critical appraisal of combined timolol and carbonic anhydrase inhibitors and the effect on ocular blood flow in glaucoma patients

, , , , &
Pages 233-241 | Published online: 30 Mar 2010

References

  • ColemanALKodjebachevaGRisk factors for glaucoma needing more attentionOpen Ophthalmol J200917384219816585
  • KassMAHeuerDKHigginbothamEJThe Ocular Hypertension Treatment Study: A randomized trial determines that topical ocular hypotensive medication delays or prevents the onset of primary open-angle glaucomaArch Ophthalmol200212070171312049574
  • LeskeMCHeijlAHymanLBengtssonBEarly Manifest Glaucoma Trial: design and baseline dataOphthalmology19991062144215310571351
  • HeijlALeskeMCBengtssonBEarly Manifest Glaucoma Trial Study GroupReduction of intraocular pressure and glaucoma progression: results from the Early Manifest Glaucoma TrialArch Ophthalmol20021201268127912365904
  • Collaborative Normal-Tension Glaucoma Study GroupThe effectiveness of intraocular pressure reduction in the treatment of normal-tension glaucomaAm J Ophthalmol19981264985059780094
  • The Advanced Glaucoma Intervention Study (AGIS): 4Comparison of treatment outcomes within race. Seven-year resultsOphthalmology1998105114611649663215
  • The Advanced Glaucoma Intervention Study (AGIS): 7The relationship between control of intraocular pressure and visual field deterioration. The AGIS InvestigatorsAm J Ophthalmol200013042944011024415
  • MuschDGillespieBLichterPVisual field progression in the Collaborative Initial Glaucoma Treatment Study: The impact of treatment and other baseline factorsOphthalmology200911620020719019444
  • ChungHSHarrisAKagemannLPeripapillary retinal blood flow in normal tension glaucomaBr J Ophthalmol19998346646910434872
  • YinZQMillarTJWidespread choroidal insufficiency in primary open-angle glaucomaJ Glaucoma1997623329075077
  • ButtZMcKillopGO’BrienCMeasurement of ocular blood flow velocity using colour Doppler imaging in low tension glaucomaEye1995929337713247
  • GalassiFSodiAUcciFOcular hemodynamics in glaucoma associated with high myopiaInt Ophthalmol19982229930510826548
  • HarrisASergottRCSpaethGLColor Doppler analysis of ocular vessel blood velocity in normal-tension glaucomaAm J Ophthalmol19941186426497977577
  • RojanapongpunPDranceSMMorrisonBJOphthalmic artery flow velocity in glaucomatous and normal subjectsBr J Ophthalmol19937725298435394
  • WeinrebRNHarrisAOcular Blood Flow in Glaucoma: The 6th Consensus Report of the World Glaucoma AssociationSection II: Clinical Measurement of Ocular Blood FlowKugler PublicationsAmsterdam, The Netherlands200959
  • TielschJMKatzJSommerAHypertension, perfusion pressure, and primary open-angle glaucoma. A population based assessmentArch Ophthalmol19951132162217864755
  • LeskeMCConnellAMWuSYRisk factors for open-angle glaucoma. The Barbados Eye StudyArch Ophthalmol19951139189247605285
  • BonomiLMarchiniGMarraffaMVascular risk factors for primary open-angle glaucoma: the Egna-Neumarkt StudyOphthalmology20001071287129310889099
  • HarrisAJonescu-CuypersCMartinBSimultaneous management of blood flow and IOP in glaucomaActa Ophthalmol Scanda200179336341
  • NiesASEvansGHShandDGRegional hemodynamic effects of beta-adrenergic blockade with propanolol in the unanesthetized primateAm Heart J197385971024629296
  • CruickshankJMThe clinical importance of cardioselectivity and lipophilicity in beta blockersAm Heart J19801001601786105819
  • McSorleyPDWarrenDJEffects of propranolol and metoprolol on the peripheral circulationBr Med J1978215981600728739
  • ElenaPPKosina-BoixMMoulinGLapalusPAutoradiographic localization of beta-adrenergic receptors in rabbit eyeInvest Ophthalmol Vis Sci198728143614413038771
  • DawidekGMBRobinsonMIBetaadrenergic receptors in human anterior optic nerve: an autoradiographic studyEye199371221268392006
  • HarrisAMartinBBeta-blockers and ocular blood flow: a perspectiveJ Glaucoma199761431459211135
  • ArendOHarrisAArendSThe acute effect of topical beta-adrenoreceptor blocking agents on retinal and optic nerve head circulationActa Ophthalmol Scand19987643499541433
  • EvansDWHarrisAChungHSEffects of long term hypotension therapy with nonselective beta-blockers on ocular hemodynamics in primary open-angle glaucomaJ Glaucoma199981121710084269
  • NetlandPASchwartzBFekeGTTakamotoTKonnoSGogerDGDiversity of response of optic nerve head circulation to timolol maleate in gel-forming solutionJ Glaucoma1999816417110376255
  • Fuchsjager-MayrlGWallyBRainerGBuehlWAggermannTKolodjaschnaJEffect of dorzolamide and timolol on ocular blood flow in patients with primary open angle glaucoma and ocular hypertensionBr J Ophthalmol2005891293129716170119
  • TamakiYAraieMTomitaKNagaharaMTomidokoroAEffect of topical beta-blockers on tissue blood flow in the human optic nerve headCurr Eye Res199716110211109395769
  • EvansDWHarrisAChungHSCantorLBGarzoziHJEffects of long-term hypotensive therapy with nonselective beta-blockers on ocular hemodynamics in primary open-angle glaucomaJ Glaucoma19998121710084269
  • GalassiFSodiARenieriGUcciFPieriBHarrisAEffects of timolol and dorzolamide on retrobulbar hemodynamics in patients with newly diagnosed primary open-angle glaucomaOphthalmologica200221612312811919438
  • HarrisASpaethGLSergottRCKatzLJCantorLBMartinBJRetrobulbar arterial hemodynamic effects of betaxolol and timolol in normal-tension glaucomaAm J Ophthalmol19951201681757639300
  • ArendOHarrisAWolterPRemkyAEvaluation of retinal haemodynamics and retinal function after application of dorzolamide, timolol and latanoprost in newly diagnosed open-angle glaucoma patientsActa Ophthalmol Scand20038147447914510794
  • LauxBERaichleMEThe effect of acetazolamide on cerebral bloow flow and oxygen utilization in the rhesus monkeyJ Clin Invest19786258559299455
  • StanescuBMichielsJThe effects of acetazolamide on the human electroretinogramInvest Ophthalmol1975149359371193808
  • SieskyBHarrisABrizendineELiterature review and meta-analysis of topical carbonic anhydrase inhibitors and ocular blood flowSurv Ophthalmol200954334619171209
  • LichterPMuschDGillespieBInterim clinical outcomes in the Collaborative Initail Glaucoma Treatment Study comparing initial treatment randomized to medications or surgeryOphthalmology20011081943195311713061
  • ClineschmidtCMWilliamRDSnyderEA randonmized trial in patients inadequately controlled with timolol alone comparing the dorzolamide-timolol combination to monotherapy with timolol or dorzolamide. Dorzolamide-Timolol Combination Study GroupOphthalmology1998105195219599787369
  • HutzelmannJOwensSSheddenAComparison of the safety and efficacy of the fixed combination of dorzolamide/timolol and the concomitant administration of dorzolamide and timolol: a clinical equivalence study. International Clinical Equivalence Study GroupBr J Ophthalmol199882124912539924327
  • KabackMScoperSArzenoGIntraocular pressure-lowering efficacy of brinzolamide 1%/timolol 0.5% fixed combination compared with brinzolamide 1% and timolol 0.5%Ophthalmology20081151728173418538406
  • WeinrebRNHarrisAOcular Blood Flow in Glaucoma: The 6th consensus report of the World Glaucoma AssociationSection III: Clinical Relevance of Ocular Blood Flow Measurements including Effects of General Medications or A Specific Glaucoma TreatmentKugler PublicationsAmsterdam, The Netherlands200960
  • SurgueMPharmacological and ocular hypotensive properties of topical carbonic anhydrase inhibitorsProg Retin Eye Res2000198711210614682
  • JanulevicieneIHarrisAKagemannLA comparison of the effects of dorzolamide/timolol fixed combination versus latanoprost on intraocular pressure and pulsatile ocular blood flow in primary open-angle glaucoma patientsActa Ophthalmol Scand20048273073715606472
  • ManniGCentofantiMGregoriDThe pulsatile ocular blood flow behaviour in open angle glaucoma patients after replacing timolol therapy with timolol and dorzolamide fixed combination: preliminary studyActa Ophthalmol Scand2002236Suppl5556
  • SchmidtKGvon RuckmannABeckerROcular pulse amplitude, intraocular pressure and beta blocker/carbonic anhydrase inhibition in combined therapy of primary open-angle glaucomaKlin Monatsbl Augenheilkd199921536136610637801
  • WeizerJSAsraniSStinnettSSThe clinical utility of dynamic contour tonometry and ocular pulse amplitudeJ Glaucoma20071670070318091458
  • YangYHulbertMBatterburyMPulsatile ocular blood flow measurements in healthy eyes: reproducibility and reference valuesJ Glaucoma199761751799211141
  • WeinrebRNHarrisAOcular Blood Flow in Glaucoma: The 6th consensus report of the World Glaucoma AssociationSection II: Clinical Measurement of Ocular Blood FlowKugler PublicationsAmsterdam, The Netherlands20092122
  • SieskyBHarrisASinesDA comparative analysis of the effects of the fixed combination of timolol and dorzolamide versus latanoprost plus timolol on ocular hemodynamics and visual function in patients with primary open-angle glaucomaJ Ocul Pharmacol Ther20062235336117076630
  • SpencerJAGiussaniDAMoorePJHansonMAIn vitro validation of Doppler indices using blood and waterJ Ultrasound Med1991103053081895370
  • OrgeFHarrisAKagemannLThe first technique for noninvasive measurements for volumetric ophthalmic artery blood flow in humansBr J Ophthalmol2002861216121912386070
  • UvaMGLongoAReibaldiMThe effect of timololdorzolamide and timolol-pilocarpine combinations on ocular blood flow in patients with glaucomaAm J Ophthalmol20061411158116016765700
  • MartınezASanchezMA comparison of the effects of 0.005% latanoprost and fixed combination dorzolamide/timolol on retrobulbar haemodynamics in previously untreated glaucoma patientsCurr Med Res Opin200622677316393432
  • MartinezASanchezMRetrobulbar haemodynamic effects of the latanoprost/timolol and the dorzolamide/timolol fixed combinations in newly diagnosed glaucoma patientsInt J Clin Pract20076181582517343668
  • MartinezASanchez-SalorioMA comparison of the long-term effects of dorzolamide 2% and brinzolamide 1%, each added to timolol 0.5%, on retrobulbar hemodynamics and intraocular pressure in open-angle glaucoma patientsJ Ocul Pharm200925239248
  • StamsTChenYBoriack-SjodinPAStructures of murine carbonic anhydrase IV and human carbonic anhydrase II complexed with brinzolamide: molecular basis of isoenzyme-drug discriminationProtein Sci199875565639541386
  • HarrisAWilliamsonTHMartinBTest/Retest reproducibility of color Doppler imaging assessment of blood flow in orbital vesselsJ Glaucoma1995428128619920687
  • StalmansISieskyBZeyenTReproducibilty of color Doppler imagingGraefes Arch Clin Exp Ophthalmol20092471531119760224
  • QuarantaLHarrisADonatoFColor Doppler imaging of ophthalmic artery blood flow velocity: a study of repeatability and agreementOphthalmology19971046536589111259
  • HarrisAArendOChungHSA comparative study of betaxolol and dorzolamide effect on ocular circulation in normal-tension glaucoma patientsOphthalmology200010743043410711877
  • ChungHHarrisHalterPRegional differences in retinal vascular reactivityInvest Ophthalmol Vis Sci19992448245310476818
  • HarrisAJonescu-CuypersCPKagemannLEffect of dorzolamide timolol combination versus timolol 0.5% on ocular bloodflow in patients with primary open-angle glaucomaAm J Ophthalmol200113249049511589868
  • WeinrebRHarrisAOcular Blood Flow in Glaucoma: The 6th consensus report of the World Glaucoma AssociationSection II: Clinical Measurement of Ocular Blood FlowKugler PublicationsAmsterdam, The Netherlands20093538
  • HarrisAArendOArendSEffects of topical dorzolamide on retinal and retrobulbar hemodynamicsActa Ophthalmol Scand1996745695729017044
  • EhrenreichDLBurnsRAAlmanRWInfluence of acetazolamide on cerebral blood flowArch Neurol19615125130
  • RassamSMPatelVKohnerEMThe effect of acetazolamide on the retinal circulationEye199376977028287997
  • TakiKKatoHEndoSCascade of acetazolamide-induced vasodilatationRes Commun Mol Pathol Pharmacol199943386391
  • StanescuBMichielsJThe effects of acetazolamide on the human electroretinogramInvest Ophthalmol1975149359371193808
  • PedersenDBStefánssonEKiilgaardJFOptic nerve pH and PO2: the effects of carbonic anhydrase inhibition, and metabolic and respiratory acidosisActa Ophthalmol Scand
  • KabackMScoperSVArzenoGIntraocular pressure-lowering efficacy of brinzolamide 1%/timolol 0.5% fixed combination compared with brinzolamide 1% and timolol 0.5%Ophthalmol200811517281734
  • WeinrebRHarrisAOcular Blood Flow in Glaucoma: The 6th consensus report of the World Glaucoma AssociationSection V: What Do We Still Need to Know?Kugler PublicationsAmsterdam, The Netherlands2009143153
  • PlangeNKaupMArendOAsymmetric visual field loss and retrobulbar haemodynamics in primary open-angle glaucomaGraefes Arch Clin Exp Ophthalmol200624497898316411100
  • ZeitzOGalambosPWagenfeldLGlaucoma progression is associated with decreased blood flow velocities in the short posterior ciliary arteryBr J Ophthalmol2006901245124816825276
  • GalassiFSodiAUcciFOcular hemodynamics and glaucoma prognosis: a color Doppler imaging studyArch Ophthalmol20031211711171514662590
  • MartinezASanchezMPredictive value of colour Doppler imaging in a prospective study of visual field progression in primary open angle glaucomaActa Ophthalmol Scand20058371672216396650
  • SatilmisMOrgulSDoublerBRate of progression of glaucoma correlates with retrobulbar circulation and intraocular pressureAm J Ophthalmol200313566466912719074
  • LamAPiltz-SeymourJDupontJLaser Doppler flowmetry in asymmetric glaucomaCurr Eye Res20053022122715804748
  • SatoEAOhtakeYShinodaKDecreased blood flow at neuroretinal rim of optic nerve corresponds with visual field deficit in eyes with normal tension glaucomaGraefes Arch Clin Exp Ophthalmol200624479580116315043
  • SatoEAShinodaKInoueMReduced choroidal blood flow can induce visual field defect in open angle glaucoma patients without intraocular pressure elevation following sclera bucklingRetina20082849349718327144
  • KozobolisVPDetorakisETGeorgiadisGSPerimetric and retrobulbar blood flow changes following carotid endarterectomyGraefes Arch Clin Exp Ophthalmol20072451639164517457602
  • MartinezASanchezMEffects of dorzolamide 2% added to timolol maleate 0.5% on intraocular pressure, retrobulbar blood flow, and the progression of visual field damage in patients with primary open-angle glaucoma: a single-center, 4-year, open-label studyClin Ther2008301120113418640468
  • The European Glaucoma Prevention Study (EGPS) GroupResults of the European Glaucoma Prevention StudyOphthalmology200511236637515745761
  • ArendOHarrisAWolterPEvaluation of retinal haemodynamics and retinal function after application of dorzolamide, timolol and latanoprost in newly diagnosed open-angle glaucoma patientsActa Ophthalmol Scand200381474912631019
  • ArendORemkyACantorLBAltitudinal visual field asymmetry is coupled with altered retinal circulation in patients with normal pressure glaucomaBr J Ophthalmol2000841008101210966955
  • MartinezASanchez-SalorioPredictors for visual field progression and effects of treatment with dorzolamide 2% or brinzolamide 1% each added to timolol 0.5% in primary open-angle glaucomaActa Ophthalmologica200910.111/j/1755–3768.2009.01595x [Epub ahead of print]
  • LoganJFRankinSJJacksonAJRetinal blood flow measurements and neuroretinal rim damage in glaucomaBr J Ophthalmol2004881049105415258023
  • HafezASBizzarroRLLeskMREvaluation of optic nerve head and peripapillary retinal blood flow in glaucoma patients, ocular hypertensives, and normal subjectsAm J Ophthalmol20031361022103114644212
  • JanulevicieneISliesoraityteISiekyBDiagnostic compatibility of structural and hemodynamic parameters in open-angle glaucoma patientsActa Ophthalmol20088655255718081900
  • JanulevicieneIEhrlichRSieskyBVisual Funcion, optic nerve structure, and ocular blood flow parameters after 1 year of glaucoma treatment with fixed combinationsEur J Ophthalmol20091979079719787599