Review of the safety, efficacy and patient acceptability of the levonorgestrel-releasing intrauterine system

References

• Abou-SettaAMAl-InanyHGFarquharCM2006Levonorgestrel-releasing intrauterine device (LNG-IUD) for symptomatic endometriosis following surgeryCochrane Database of Systematic ReviewsIssue 4
   Web of Science ®Google Scholar
• AnderssonKBatarIRyboG1992Return to fertility after removal of a levonorgestrel-releasing intrauterine device and Nova-TContraception46575841493717
   PubMed Web of Science ®Google Scholar
• AnderssonKOdlindVRyboG1994Levonorgestrel-releasing and copper-releasing (Nova T) IUDs during five years of use. A randomized comparative trialContraception4956728137626
   PubMed Web of Science ®Google Scholar
• AndersonJKRyboG1990Levonorgestrel-releasing intrauterine device in the treatment of menorrhagiaBr J Obstet Gynaecol9769042119218
   PubMedGoogle Scholar
• BackmanTHuhtalaSLuotoR2002Advance information improves user satisfaction with the levonorgestrel intrauterine systemObstet Gynecol996081312039121
   PubMed Web of Science ®Google Scholar
• BackmanTRauramoIHuhtalaS2004Pregnancy during the use of levonorgestrel intrauterine systemAm J Obstet Gynecol19050414749634
   PubMed Web of Science ®Google Scholar
• BackmanTRauramoIJaakkolaK2005Use of the levonorgestrel-releasing intrauterine system and breast cancerObstet Gynecol106813716199640
   PubMed Web of Science ®Google Scholar
• BahamondesLEspejo-ArceXHidalgoMM2006A cross-sectional study of the forearm bone density of long-term users of levonorgestrel-releasing intrauterine systemHum Reprod211316916373404
   PubMed Web of Science ®Google Scholar
• BlumenthalPDTrussellJSinghRH2006Cost-effectiveness of treatments for dysfunctional uterine bleeding in women who need contraceptionContraception742495816904420
   PubMed Web of Science ®Google Scholar
• BonachoIPitaSGomez-BesteiroMI2001The importance of the removal of the intrauterine device in genital colonization by actinomycesGynecol Obstet Invest521192311586040
   PubMed Web of Science ®Google Scholar
• BraghetoaAMCasertabNBahamondesL2007Effectiveness of the levonorgestrel-releasing intrauterine system in the treatment of adenomyosis diagnosed and monitored by magnetic resonance imagingContraception76195917707716
   PubMed Web of Science ®Google Scholar
• BudimanHKümperCMylonasI2007Pregnancy in a patient with a displaced levonorgestrel-releasing intrauterine system: a case reportArch Gynecol Obstet276263417356827
   PubMedGoogle Scholar
• ChanSTamWYeoW2007A randomised controlled trial of prophylactic levonorgestrel intrauterine system in tamoxifen-treated womenBJOG1141510517995495
   PubMed Web of Science ®Google Scholar
• CleggJPGuestJFHurskainenR2007Cost-utility of levonorgestrel intrauterine system compared with hysterectomy and second generation endometrial ablative techniques in managing patients with menorrhagia in the UKCurr Med Res Opin2316374817559758
   PubMed Web of Science ®Google Scholar
• ChoSHNamAKimHY2008Clinical effects of the levonorgestrel-releasing intrauterine device in patients with adenomyosisAm J Obstet Gynecol198373.e1718177833
   PubMed Web of Science ®Google Scholar
• ChrismanCRibeiroPDaltonVK2007The levonorgestrel-releasing intrauterine system: an updated review of the contraceptive and non-contraceptive usesClin Obstet Gynecol508869717982331
   PubMed Web of Science ®Google Scholar
• d’ArcanguesC2006WHO statement on hormonal contraception and bone healthContraception73443416627029
   PubMed Web of Science ®Google Scholar
• El TagyASakrESokalDC2003Safety and acceptability of post-abortal IUD insertion and the importance of counsellingContraception672293412618259
   PubMed Web of Science ®Google Scholar
• ESHRE Capri Workshop Group2008Intrauterine devices and intrauterine systemsHum Reprod Update1419720818400840
   PubMed Web of Science ®Google Scholar
• FarleyTMMRowePJMeirikO1992Intrauterine devices and pelvic inflammatory disease: an international perspectiveLancet33978581347812
   PubMed Web of Science ®Google Scholar
• ForrestAAmarakoneILordJ2008Retained hormone release capsule following removal of Mirena intrauterine systemBJOG115130118053112
   PubMed Web of Science ®Google Scholar
• FrenchRVan VlietHCowanF2004Hormonally impregnated intrauterine systems (IUSs) versus other forms of reversible contraceptives as effective methods of preventing pregnancyCochrane Database of Systematic ReviewsIssue 3 Art. No: CD001776
   Google Scholar
• [FSRH] Faculty of Sexual and Reproductive Healthcare Guidance. Clinical Effectiveness Unit. 2007. Intrauterine Contraception.
   Google Scholar
• GardnerFJKonjeJCAbramsKR2000Endometrial protection from tamoxifen-stimulated changes by a levonorgestrel-releasing intrauterine system: a randomised controlled trialLancet3561711711095258
   PubMed Web of Science ®Google Scholar
• GrimesDA2000Intrauterine device and upper-genital-tract infectionLancet356101310911041414
   PubMed Web of Science ®Google Scholar
• GrimesDALopezLMManionC2007Cochrane systematic reviews of IUD trials: lessons learnedContraception75S55S917531618
   PubMed Web of Science ®Google Scholar
• GrimesDMishellDJr2008Intrauterine contraception as an alternative to interval tubal sterilizationContraception776918082660
   PubMed Web of Science ®Google Scholar
• GrimesDASchulzKF2001Antibiotic prophylaxis for intrauterine contraceptive device insertionCochrane Database Syst RevCD001327
   Google Scholar
• GuttingerACritchleyHO2007Endometrial effects of intrauterine levonorgestrelContraception75S93S817531624
   PubMed Web of Science ®Google Scholar
• Haimov-KochmanRAmsalemHAdoniA2003Management of a perforated levonorgestrel-medicated intrauterine device – a pharma-cokinetic study: case reportHum Reprod181231312773451
   PubMed Web of Science ®Google Scholar
• HurskainenRTeperiJRissanenP2004Clinical outcomes and costs with the levonorgestrel-releasing intrauterine system or hysterectomy for treatment of menorrhagia: randomized trial 5-year follow-upJAMA29114566315039412
   PubMed Web of Science ®Google Scholar
• InkiP2007Long-term use of the levonorgestrel-releasing intrauterine systemContraception756 SupplS161617531611
   PubMed Web of Science ®Google Scholar
• InkiPHurskainenRPaloP2002Comparison of ovarian cyst formation in women using the levonorgestrel-releasing intrauterine system vs. hysterectomyUltrasound Obstet Gynecol20381512383322
   PubMed Web of Science ®Google Scholar
• IstreOQvigstadE2007Current treatment options for abnormal uterine bleeding: an evidence-based approachBest Pract Res Clin Obstet Gynaecol2169051317499553
   PubMed Web of Science ®Google Scholar
• JensenJTNelsonALAntonioC2008Subject and clinician experience with the levonorgestrel-releasing intrauterine systemContraception7722918082662
   PubMed Web of Science ®Google Scholar
• JonssonBLandgrenB-MEnerothP1991Effects of various IUDs on the composition of cervical mucusContraception43447581914458
   PubMed Web of Science ®Google Scholar
• KresowikJRyanGLVan VoorhisBJ2008Progression of atypical endometrial hyperplasia to adenocarcinoma despite intrauterine progesterone treatment with the levonorgestrel-releasing intrauterine systemObstet Gynecol111547918239018
   PubMed Web of Science ®Google Scholar
• KadirRAChiC2007Levonorgestrel intrauterine system: bleeding disorders and anticoagulant therapyContraception75S123S917531603
   PubMed Web of Science ®Google Scholar
• KaunitzAM2007Progestin-releasing intrauterine systems and leiomyomaContraception75S130S317531604
   PubMed Web of Science ®Google Scholar
• LähteenmäkiPRauramoIBackmanT2000The levonorgestrel intrauterine system in contraceptionSteroids65693711108878
   PubMed Web of Science ®Google Scholar
• LethabyAECookeIReesM2005Progesterone or progestogen-releasing intrauterine systems for heavy menstrual bleedingCochrane Database of Systematic ReviewsIssue 4 Art. No: CD002126
   Web of Science ®Google Scholar
• LockhatFBEmemboluJEKonjeJC2005Serum and peritoneal fluid levels of levonorgestrel in women with endometriosis who were treated with an intrauterine contraceptive device containing levonorgestrelFertil Steril8339840415705381
   PubMed Web of Science ®Google Scholar
• LuukkainenTLahteenmakiPToivonenJ1990Levonorgestrel-releasing intrauterine deviceAnn Med2285902113816
   PubMed Web of Science ®Google Scholar
• MarjoribanksJLethabyAFarquharC2006Surgery versus medical therapy for heavy menstrual bleedingCochrane Database Syst Rev192CD00385516625593
   PubMed Web of Science ®Google Scholar
• MohllajeeAPCurtisKMPetersonHB2006Does insertion and use of an intrauterine device increase the risk of pelvic inflammatory disease among women with sexually transmitted infection? A systematic reviewContraception731455316413845
   PubMed Web of Science ®Google Scholar
• [NICE] National Institute for Health and Clinical Excellence Guidelines2005Long acting reversible contraception
   Google Scholar
• NilssonCGLahteenmakiPLuukkainenT1980Levonorgestrel plasma concentrations and hormone profiles after insertion and after one year of treatment with a levonorgestrel-IUDContraception21225336771090
   PubMed Web of Science ®Google Scholar
• OdlindV1996Modern intrauterine devicesBaillieres Clin Obstet Gynaecol1055678736722
   PubMed Web of Science ®Google Scholar
• PakarinenPToivonenJLuukkainenT2003Randomized comparison of levonorgestrel- and copper-releasing intrauterine systems immediately after abortion, with 5 years’ follow-upContraception6831412878284
   PubMed Web of Science ®Google Scholar
• PettaCAFerrianiRAAbrãoMS2005Randomized clinical trial of a levonorgestrel-releasing intrauterine system and a depot GnRH analogue for the treatment of chronic pelvic pain in women with endometriosisHum Reprod201993815790607
   PubMed Web of Science ®Google Scholar
• PisoniCNCuadradoMJKhamashtaMA2005Treatment of menorrhagia associated with oral anticoagulation: efficacy of levonorgestrel releasing intrauterine deviceThromb Res115Suppl 11212
   Google Scholar
• PragerSDarneyPD2007The levonorgestrel intrauterine system in nulliparous womenContraception756 SupplS12517531602
   PubMed Web of Science ®Google Scholar
• Progress in Reproductive Health Research, Issue 60, WHO 2002.
   Google Scholar
• RiphagenFE2000Intrauterine application of progestins in hormone replacement therapy: a reviewClimacteric319921111910622
   PubMedGoogle Scholar
• RönnerdagMOdlindV1999Health effects of long-term use of the intrauterine levonorgestrel-releasing system. A follow-up study over 12 years of continuous useActa Obstet Gynecol Scand787162110468065
   PubMed Web of Science ®Google Scholar
• ShaamashAHSayedGHussienM2005A comparative study of the levonorgestrel-releasing intrauterine system Mirena versus the Copper T380A intrauterine device during lactation: breast-feeding performance, infant growth and infant developmentContraception723465116246660
   PubMed Web of Science ®Google Scholar
• Sitruk-WareR2007The levonorgestrel intrauterine system for use in peri- and postmenopausal womenContraception75S155S6017531609
   PubMed Web of Science ®Google Scholar
• SivinISternJCoutinhoE1991Prolonged intrauterine contraception: a seven-year randomized study of the levonorgestrel 20 mcg/day (LNg 20) and the Copper T380 Ag IUDSContraception44473801797462
   PubMed Web of Science ®Google Scholar
• SoysalSSoysalME2005The efficacy of levonorgestrel-releasing intrauterine device in selected cases of myoma-related menorrhagia: a prospective controlled trialGynecol Obstet Invest59293515377823
   PubMed Web of Science ®Google Scholar
• SuhonenSHaukkamaaMJakobssonT2004Clinical performance of a levonorgestrel-releasing intrauterine system and oral contraceptives in young nulliparous women: a comparative studyContraception694071215105064
   PubMed Web of Science ®Google Scholar
• ThonneauPFAlmontTE2008Contraceptive efficacy of intrauterine devicesAm J Obstet Gynecol1982485318221924
   PubMed Web of Science ®Google Scholar
• ToivonenJLuukkainenTAllonenH1991Protective effect of intrauterine release of levonorgestrel on pelvic infection: three years‘ comparative experience of levonorgestrel- and copper-releasing intrauterine devicesObstet Gynecol7726141899136
   PubMed Web of Science ®Google Scholar
• TrinhXBTjalmaWAMakarAP2008Use of the levonorgestrel-releasing intrauterine system in breast cancer patientsFertil Steril90172217706209
   PubMed Web of Science ®Google Scholar
• VarmaRSinhaDGuptaJK2006Non-contraceptive uses of levonorgestrel-releasing hormone system (LNG-IUS) – a systematic enquiry and overviewEur J Obstet Gynecol Reprod Biol12592816325993
   PubMed Web of Science ®Google Scholar
• VarmaRSonejaHBhatiaK2008The effectiveness of a levonorgestrel-releasing intrauterine system (LNG-IUS) in the treatment of endometrial hyperplasia-A long-term follow-up studyEur J Obstet Gynecol Reprod Biol Apr 25 [Epub ahead of print]
   Web of Science ®Google Scholar
• Van HoudenhovenKvan KaamKJAFvan GrootheestAC2006Uterine perforation in women using a levonorgestrel-releasing intrauterine systemContraception732576016472566
   PubMed Web of Science ®Google Scholar
• VercelliniPFrontinoGDe GiorgiO2003Comparison of a levonorgestrel-releasing intrauterine device versus expectant management after conservative surgery for symptomatic endometriosis: a pilot studyFertil Steril80305912909492
   PubMed Web of Science ®Google Scholar
• WHO2004Medical eligibility criteria for contraceptive useWorld Health Organization URL: http://www.who.int/reproductive-health/publications/mec/7_iud.pdf
   Google Scholar
• World Health Organization Department of Reproductive Health and Research (WHO/RHR) and Johns Hopkins Bloomberg School of Public Health/Center for Communication Programs (CCP), INFO Project2007Family Planning: A Global Handbook for ProvidersBaltimore and GenevaCCP and WHO
   Google Scholar
• WildemeerschD2007New frameless and framed intrauterine devices and systems – an overviewContraception756 SupplS829217531623
   PubMed Web of Science ®Google Scholar
• WildemeerschDJanssensDPylyserK2007bManagement of patients with non-atypical and atypical endometrial hyperplasia with a levonorgestrel-releasing intrauterine system: long-term follow-upMaturitas57210317270370
   PubMed Web of Science ®Google Scholar
• WildemeerschDPylyserKWeverN2007aEndometrial safety after 5 years of continuous combined transdermal estrogen and intrauterine levonorgestrel delivery for postmenopausal hormone substitutionMaturitas57205917227699
   PubMed Web of Science ®Google Scholar
• ZalelYGamzuRShulmanA2003The progestative effect of the levonorgestrel-releasing intrauterine system – when does it manifest?Contraception67473612814817
   PubMed Web of Science ®Google Scholar
• XiaoBWuSCChongJ2003Therapeutic effects of the levonorgestrel-releasing intrauterine system in the treatment of idiopathic menorrhagiaFertil Steril79963912749438
   PubMed Web of Science ®Google Scholar