References
- AltmannSWDavisHRJrZhuLJNiemann-Pick C1 Like 1 protein is critical for intestinal cholesterol absorptionScience20043031201414976318
- AnonThe Lipid Research Clinics Coronary Primary Prevention Trial results. I. Reduction in incidence of coronary heart diseaseJAMA1984251351646361299
- AnonRandomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S)Lancet1994344138397968073
- BallantyneCAbateNZhongYDose-comparison study of the combination of ezetimibe and simvastatin (Vytorin) versus atorvastatin in patients with hypercholesterolemia. the Vytorin Versus Atorvastatin (VYVA Study)Am Heart J20051494647315864235
- BallantyneCSosefFDuffieldEEfficacy and safety of rosuvastatin plus ezetimibe in high-risk patients: results from the EXPLORER studyAtherosclerosis Supplement20067552 abstract
- BallantyneCMBlazingMAKingTREfficacy and safety of ezetimibe co-administered with simvastatin compared with atorvastatin in adults with hypercholesterolemiaAm J Cardiol20049314879415194018
- BallantyneCMHouriJNotarbartoloAEffect of ezetimibe coadministered with atorvastatin in 628 patients with primary hypercholesterolemia: a prospective, randomized, double-blind trialCirculation200310724091512719279
- BrewerHBJrSantamarina-FojoSNew insights into the role of the adenosine triphosphate-binding cassette transporters in high-density lipoprotein metabolism and reverse cholesterol transportAm J Cardiol2003913E11E
- CarsteaEDMorrisJAColemanKGNiemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasisScience1997277228319211849
- CastelliWPAndersonKWilsonPWLipids and risk of coronary heart disease. The Framingham StudyAnn Epidemiol199222381342260
- CatapanoALDavidsonMHBallantyneCMLipid-altering efficacy on the ezetimibe/simvastatin single tablet versus rosuvastatin in hypercholesterolemic patientsCurr Med Res Opin20062220415317022864
- CollinsRArmitageJParishSEffects of cholesterol-lowering with simvastatin on stroke and other major vascular events in 20536 people with cerebrovascular disease or other high-risk conditionsLancet20043637576715016485
- CookRPCookRPCholesterol. Distribution of sterols in organisms and in tissuesCholesterol. Chemistry, biochemistry, and pathology1958New YorkAcademic Press14580
- DavidsonMHRobinsonJGSafety of aggressive lipid managementJ Am Coll Cardiol20074917536217466224
- DaviesJPIoannouYATopological analysis of Niemann-Pick C1 protein reveals that the membrane orientation of the putative sterol-sensing domain is identical to those of 3-hydroxy-3-methylglutaryl-CoA reductase and sterol regulatory element binding protein cleavage-activating proteinJ Biol Chem2000275243677410821832
- DenkeMPearsonTMcBridePEzetimibe added to ongoing statin therapy improves LDL-C goal attainment and lipid profile in patients with diabetes or metabolic syndromeDiabetes Vasc Dis Res2006393102
- DietschyJMTurleySDSpadyDKRole of liver in the maintenance of cholesterol and low density lipoprotein homeostasis in different animal species, including humansJ Lipid Res1993341637598245716
- DownsJRClearfieldMTyrolerHAAir Force/Texas Coronary Atherosclerosis Prevention Study (AFCAPS/TEXCAPS): additional perspectives on tolerability of long-term treatment with lovastatinAm J Cardiol2001871074911348605
- DujovneCAEttingerMPMcNeerJFEfficacy and safety of potent new selective cholesterol absorbtion inhibitor, ezetimibe in patients with primary hypercholesterolemiaAm J Cardiol2002901092712423709
- FarnierMRothEGil-ExtremeraBEzetimibe/Simvastatin + Fenofibrate Study GroupEfficacy and safety of the coadministration of ezetimibe/simvastatin with fenofibrate in patients with mixed hyperlipidemiaAm Heart J2007153335.e1817239698
- FeldmanTKorenMInsullWJrTreatment of high-risk patients with ezetimibe plus simvastatin co-administration versus simvastatin alone to attain National Cholesterol Education Program Adult Treatment Panel III low-density lipoprotein cholesterol goalsAm J Cardiol2004931481615194017
- FoleyKASimpsonRJJrCrouseJRIIIEffectiveness of statin titration on low-density lipoprotein cholesterol goal attainment in patients at high risk of atherogenic eventsAm J Cardiol200392798112842255
- FrickMHEloOHaapaKHelsinki Heart Study: primary-prevention trial with gemfibrozil in middle-aged men with dyslipidemia. Safety of treatment, changes in risk factors, and incidence of coronary heart diseaseN Engl J Med19873171237453313041
- GagneCBaysHEWeissSREfficacy and safety of ezetimibe added to ongoing statin therapy for treatment of patients with primary hypercholesterolemiaAm J Cardiol20029010849112423708
- GagneCBaysHEWeissSREfficacy and safety of ezetimibe added to ongoing statin therapy for treatment of patients with primary hypercholesterolemiaAm J Cardiol20029010849112423708
- Garcia-CalvoMThe target of ezetimibe is Niemann-Pick C1-Like 1 (NPC1L1)Proc Natl Acad Sci USA20051028132715928087
- GoettschWGYinDDAlemaoEStatins are less effective in common daily practice among patients with hypercholesterolemia: the REALITY-PHARMO studyCurr Med Res Opin20042010253315265247
- GoldbergRBGuytonJRMazzoneTEzetimibe/simvastatin vs atorvastatin in patients with type 2 diabetes mellitus and hypercholesterolemia: the Vytal studyMayo Clin Proc20068115798817165637
- GoldsteinJLBrownMSRegulation of mevalonate pathwayNature1990343425301967820
- GrundySMCleemanJIMerzCNImplications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III GuidelinesJ Am Coll Cardiol2004447203215358046
- IllingworthDRDuellPBConnorWEFeligPBaxterJDFrohmanLADisorders of lipid metabolismEndocrinology and metabolism1995New YorkMcGraw-Hill1315403
- KerznerBCorbelliJSharpSEfficacy and safety of ezetimibe coadministered with lovastatin in primary hypercholesterolemiaAm J Cardiol2003914182412586255
- KosoglouTStatkevichPJohnson-LevonasAOEzetimibe: a review of its metabolism, pharmacokinetics and drug interactionsClin Pharmacokinet2005444679415871634
- LammertFWangDQHNew insights into the genetic regulation of intestinal cholesterol absorbtionGastroenterology20051297183416083725
- LavoieMAEzetimibe and cholesterol absorptionCan J Clin Pharmacol200310Suppl A7A12A
- LeibovitzEGavishDBitzurREfficacy and safety of rosuvastatin-ezetimibe combination for the treatment of severe hypercholesterolemiaAtheroscler Suppl20067554 abstract
- LevyESpahisSSinnetDIntestinal cholesterol transport proteins: an update and beyondCurr Opin Lipidol2007183101817495606
- ManninenVEloMOFrickMHLipid alterations and decline in the incidence of coronary heart disease in the Helsinki Heart StudyJAMA1988260641513164788
- McKenneyJMFarnierMLoKWSafety and efficacy of long-term co-administration of fenofibrate and ezetimibe in patients with mixed hyperlipidemiaJ Am Coll Cardiol2006471584716630994
- MelaniLMillsRHassmanDEfficacy and safety of ezetimibe coadministered with pravastatin in patients with primary hypercholesterolemia: a prospective, randomized, double-blind trialEur Heart J2003247172812713766
- NealRCJonesPHLipid-lowering: can ezetimibe help close the treatment gap?Cleve Clin J Med2003707778314518572
- ParkerRALarkRWSitSYSelective inhibition of cholesterol synthesis in liver versus extrahepatic tissues by HMG-CoA reductase inhibitorsJ Lipid Res1990311271822401858
- PatrickJEKosoglouTStauberKLDisposition of the selective cholesterol absorption inhibitor ezetimibe in healthy male subjectsDrug Metab Dispos2002129174854
- PearsonTDenkeMMcBridePEzetimibe added to statin therapy reduces LDL-C and improves goal attainment in patients with hypercholesterolemia2004American College of Cardiology 53rd Annual MeetingMarch 7-10, 2004New Orleans abstract
- RepaJJMangelsdorfDJThe liver X receptor gene team: potential new players in atherosclerosisNat Med200281243812411951
- RepaJJTurleySDLobaccaroJARegulation of absorption and ABC1-mediated efflux of cholesterol by RXR heterodimersScience20002891524910968783
- RussellDWNuclear orphan receptors control cholesterol catabolismCell1999975394210367881
- SalenGTintGSSheferSIncreased sitosterol absorption is offset by rapid elimination to prevent accumulation in heterozygotes with sitosterolemiaArterioscler Thromb19991256381576118
- SeedorfUEngelTLuekenACholesterol absorption inhibitor Ezetimibe blocks uptake of oxidized LDL in human macrophagesBiochem Biophys Res Commun200432013374115303279
- ShepherdJCobbeSMFordIPrevention of coronary heart disease with pravastatin in men with hypercholesterolemia. West of Scotland Coronary Prevention Study GroupN Engl J Med1995333130177566020
- ShepherdJLipids in health and diseaseBiochem Soc Trans2004321051615506961
- StamlerJWentworthDNeatonJDIs relationship between serum cholesterol and risk of premature death from coronary heart disease continuous and graded? Findings in 356,222 primary screenees of the Multiple Risk Factor Intervention Trial (MRFIT)JAMA1986256282383773199
- SteinbergDWitztumJLLipoproteins and atherogenesis. Current conceptsJAMA19902643047522243434
- SviridovDDSafonovaIGPavlovMYInhibition of cholesterol synthesis by lovastatin tested on six human cell types in vitroLipids19902517792159099
- Van HeekMFarleyCComptonDSComparison of the activity and disposition of the novel cholesterol absorption inhibitor, SCH58235, and its glucuronide, SCH60663Br J Pharmacol200012917485410780982
- WangDQHRegulation of intestinal cholesterol absorbtionAnnu Rev Physiol2007692214817002594
- WilsonPWGarrisonRJCastelliWPPrevalence of coronary heart disease in the Framingham Offspring Study: role of lipoprotein cholesterolsAm J Cardiol198046649547416024