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Review

Molecular Signature Analysis: the Potential of gene-expression Analysis in Cardiomyopathy

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Pages 793-808 | Published online: 25 Oct 2005

Bibliography

  • SOLVD Investigators : Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure.N. Engl. J.Med., 325(5), 293–302 (1991).
  • Poole -WilsonPA, SwedbergK, Cleland,JGet al..: Comparison of carvedilol and metoprolol on clinical outcomes in patients with chronic heart failure in the Carvedilol Or Metoprolol European Trial (COMET): randomised controlled trial. Lancet, 362(9377), 7–13 (2003).
  • Pitt B , ZannadF, RemmeWJet al..: The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators. N. Engl. J. Med., 341(10), 709–717 (1999).
  • Granger CB , McMurrayJJ, YusufSet al..: Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function intolerant to angiotensin-converting-enzyme inhibitors: the CHARM-Alternative trial. Lancet, 362(9386), 772–776 (2003).
  • Cleland JGF , DaubertJC, ErdmannEet al..: The Effect of Cardiac Resynchronization on Morbidity and Mortality in Heart Failure. N. Engl. J. Med., 352(15), 1539–1549 (2005).
  • Bardy GH , LeeKL, MarkDBet al..: Amiodarone or an implantable cardioverter-defibrillator for congestive heart failure. N. Engl. J. Med., 352(3), 225–237 (2005).
  • Rose EA , GelijnsAC, MoskowitzAJet al..: Long-term mechanical left ventricular assistance for end stage heart failure. N. Engl. J.Med., 345(20), 1435–1443 (2001).
  • Reynolds MR , JosephsonME: MADIT II (second Multicenter Automated Defibrillator Implantation Trial) debate: risk stratification, costs, and public policy.Circulation, 108(15), 1779–1783 (2003).
  • Cope JT , KazaAK, ReadeCCet al..: A cost comparison of heart transplantation versus alternative operations for cardiomyopathy. Ann. Thorac. Surg., 72(4), 1298–1305 (2001).
  • Pulignano G , Del Sindaco D, Tavazzi L et al.: Clinical features and outcomes of elderly out-patients with heart failure followed up in hospital cardiology units: data from a large nationwide cardiology database (IN-CHF Registry). Am. Heart J., 143(1), 45–55 (2002).
  • Cintron G , JohnsonG, FrancisG, CobbF, CohnJN: Prognostic significance of serial changes in left ventricular ejection fraction in patients with congestive heart failure. The V-HeFT VA Co-operative Studies Group.Circulation, 87(6 Suppl. 6), VI17–VI23 (1993).
  • Uretsky BF , SheahanRG: Primary prevention of sudden cardiac death in heart failure: will the solution be shocking?J. Am. Coll. Cardiol., 30(7), 1589–1597 (1997).
  • Dries DL , SweitzerNK, DraznerMH, StevensonLW, GershBJ: Prognostic impact of diabetes mellitus in patients with heart failure according to the etiology of left ventricular systolic dysfunction.J. Am. Coll. Cardiol., 38(2), 421–428 (2001).
  • Dries DL , ExnerDV, DomanskiMJ, GreenbergB, StevensonLW: The prognostic implications of renal insufficiency in asymptomatic and symptomatic patients with left ventricular systolic dysfunction.J. Am. Coll. Cardiol., 35(3), 681–689 (2000).
  • Lee WH , PackerM: Prognostic importance of serum sodium concentration and its modification by converting-enzyme inhibition in patients with severe chronic heart failure.Circulation, 73(2), 257–267 (1986).
  • McDonagh TA , CunninghamAD, Morrison,CEet al..: Left ventricular dysfunction, natriuretic peptides, and mortality in an urban population. Heart, 86(1), 21–26 (2001).
  • Anker SD , DoehnerW, RauchhausMet al..: Uric acid and survival in chronic heart failure: validation and application in metabolic, functional, and hemodynamic staging. Circulation, 107(15), 1991–1997 (2003).
  • Barrans JD , StamatiouD, LiewCC: Construction of a Human Cardiovascular cDNA Microarray: Portrait of the Failing Heart.Biochem. Biophys. Res. Comm., 280(4), 964–969 (2001).
  • Alizadeh A , EisenM, Davis,REet al..: The lymphochip: a specialized cDNA microarray for the genomic-scale analysis of gene expression in normal and malignant lymphocytes. Cold Spring Harb. Symp. Quant. Biol.6471–78 (1999).
  • GeneChip®, expression analysis data. Analysis fundamentals. Affymetrix, CA, USA (2003).
  • Barrans JD , AllenPD, StamatiouD, DzauVJ, LiewCC: Global gene expression profiling of end stage dilated cardiomyopathy using a human cardiovascular-based cDNA microarray.Am. J. Pathol., 160(6), 2035–2043 (2002).
  • Tan FL , MoravecCS, Li,Jet al..: The gene expression fingerprint of human heart failure. Proc. Natl Acad. Sci. USA, 99(17), 11387–11392 (2002).
  • Yung CK , HalperinVL, TomaselliGF, WinslowRL: Gene expression profiles in end stage human idiopathic dilated cardiomyopathy: altered expression of apoptotic and cytoskeletal genes.Genomics, 83(2), 281–297 (2004).
  • Steenman M , LamiraultG, Le Meur, N et al.: Distinct molecular portraits of human failing hearts identified by dedicated cDNA microarrays. Eur. J. Heart Fail., 7(2), 157–165 (2005).
  • Steenman M , ChenYW, Le Cunff M et al.: Transcriptomal analysis of failing and nonfailing human hearts. Physiol. Genomics, 12(2), 97–112 (2003).
  • Kaab S , BarthAS, MargerieDet al..: Global gene expression in human myocardium-oligonucleotide microarray analysis of regional diversity and transcriptional regulation in heart failure. J. Mol. Med., 82(5), 308–316 (2004).
  • Boheler KR , VolkovaM, Morrell,Cet al..: Sex- and age-dependent human transcriptome variability: implications for chronic heart failure. Proc. Natl Acad. Sci. USA, 100(5), 2754–2759 (2003).
  • Kittleson MM , MinhasKM, IrizarryRAet al..: Gene expression analysis of ischemic and nonischemic cardiomyopathy: shared and distinct genes in the development of heart failure. Physiol. Genomics, 21(3), 299–307 (2005).
  • Kittleson MM , MinhasKM, IrizarryRAet al..: Gene expression in giant cell myocarditis: Altered expression of immune response genes. Int. J. Cardiol., 102(2), 333–340 (2005).
  • Hwang JJ , AllenPD, Tseng,GCet al..: Microarray gene expression profiles in dilated and hypertrophic cardiomyopathic end stage heart failure. Physiol. Genomics, 10(1), 31–44 (2002).
  • Hall JL , GrindleS, Han,Xet al..: Genomic profiling of the human heart before and after mechanical support with a ventricular assist device reveals alterations in vascular signaling networks. Physiol. Genomics, 17(3), 283–291 (2004).
  • Chen Y , ParkS, LiYet al..: Alterations of gene expression in failing myocardium following left ventricular assist device support. Physiol. Genomics, 14(3), 251–260 (2003).
  • Chen MM , AshleyEA, Deng,DXet al..: Novel role for the potent endogenous inotrope apelin in human cardiac dysfunction. Circulation, 108(12), 1432–1439 (2003).
  • Blaxall BC , Tschannen-MoranBM, MilanoCA, KochWJ: Differential gene expression and genomic patient stratification following left ventricular assist device support.J. Am. Coll. Cardiol., 41(7), 1096–1106 (2003).
  • Margulies , KB, Matiwala S, Cornejo C et al.: Mixed messages: transcription patterns in failing and recovering human myocardium. Circ. Res.1–8 (2005).
  • Tusher VG , TibshiraniR, ChuG: Significance analysis of microarrays applied to the ionizing radiation response.Proc. Natl Acad. Sci. USA, 98(9), 5116–5121 (2001).
  • Cook SA , RosenzweigA: DNA microarrays: implications for cardiovascular medicine.Circ. Res., 91(7), 559–564 (2002).
  • Simon R , RadmacherMD, DobbinK, McShaneLM: Pitfalls in the use of DNA microarray data for diagnostic and prognostic classification.J. Natl Cancer Inst., 95(1), 14–18 (2003).
  • Dudoit S , GentlemanRC, QuackenbushJ: Open source software for the analysis of microarray data.BioTechniques Supplement 45–51 (2003).
  • Carey VJ , GentryJ, WhalenE, GentlemanR: Network structures and algorithms in Bioconductor.Bioinformatics, 21(1), 135–136 (2005).
  • Huang X , PanW, GrindleSet al..: A comparative study of discriminating human heart failure etiology using gene expression profiles. BMC. Bioinformatics, 6(1), 205 (2005).
  • Tibshirani R , HastieT, NarasimhanB, ChuG: Diagnosis of multiple cancer types by shrunken centroids of gene expression.Proc. Natl Acad. Sci. USA, 99(10), 6567–6572 (2002).
  • Lossos IS , CzerwinskiDK, AlizadehAAet al..: Prediction of Survival in Diffuse Large-B-Cell Lymphoma Based on the Expression of Six Genes. N. Engl. J. Med., 350(18), 1828–1837 (2004).
  • Paik S , ShakS, TangGet al..: A Multigene Assay to Predict Recurrence of Tamoxifen-Treated, Node-Negative Breast Cancer. N. Engl. J. Med., 351(27), 2817–2826 (2004).
  • van de Vijver MJ , HeYD, van’t Veer LJ et al.: A gene-expression signature as a predictor of survival in breast cancer. N. Engl. J. Med., 347(25), 1999–2009 (2002).
  • Rosenwald A , WrightG, ChanWCet al..: The use of molecular profiling to predict survival after chemotherapy for diffuse large-B-cell lymphoma. N. Engl. J. Med., 346(25), 1937–1947 (2002).
  • Bullinger L , DohnerK, BairEet al..: Use of gene-expression profiling to identify prognostic subclasses in adult acute myeloid leukemia. N. Engl. J.Med., 350(16), 1605–1616 (2004).
  • Valk PJ , VerhaakRG, BeijenMAet al..: Prognostically useful gene-expression profiles in acute myeloid leukemia. N. Engl. J.Med., 350(16), 1617–1628 (2004).
  • Dhanasekaran SM , BarretteTR, GhoshDet al..: Delineation of prognostic biomarkers in prostate cancer. Nature, 412(6849), 822–826 (2001).
  • Lapointe J , LiC, HigginsJPet al..: Gene expression profiling identifies clinically relevant subtypes of prostate cancer. Proc. Natl Acad. Sci. USA, 101(3), 811–816 (2004).
  • Pomeroy SL , TamayoP, GaasenbeekMet al..: Prediction of central nervous system embryonal tumour outcome based on gene expression. Nature, 415(6870), 436–442 (2002).
  • Kittleson MM , YeSQ, IrizarryRAet al..: Identification of a gene expression profile that differentiates between ischemic and nonischemic cardiomyopathy. Circulation, 110(22), 3444–3451 (2004).
  • Brazma A , HingampP, QuackenbushJet al..: Minimum information about a microarray experiment (MIAME)-toward standards for microarray data. Nature Genet., 29(4), 365–371 (2001).
  • Liu ET , KaruturiKR: Microarrays and clinical investigations.N. Engl. J.Med., 350(16), 1595–1597 (2004).
  • Mirotsou M , WatanabeCMH, SchultzPG, PrattRE, DzauVJ: Elucidating the molecular mechanism of cardiac remodeling using a comparative genomic approach.Physiol. Genomics, 15(2), 115–126 (2003).
  • Felker GM , ThompsonRE, HareJMet al..: Underlying causes and long-term survival in patients with initially unexplained cardiomyopathy. N. Engl. J. Med., 342(15), 1077–1084 (2000).
  • Ardehali H , QasimA, CappolaTet al..: Endomyocardial biopsy plays a role in diagnosing patients with unexplained cardiomyopathy. Am. Heart J., 147(5), 919–923 (2004).
  • Deckers JW , HareJM, BaughmanKL: Complications of transvenous right ventricular endomyocardial biopsy in adult patients with cardiomyopathy: a 7 year survey of 546 consecutive diagnostic procedures in a tertiary referral center.J. Am. Coll. Cardiol., 19(1), 43–47 (1992).
  • Felker GM , HuW, HareJMet al..: The spectrum of dilated cardiomyopathy. The Johns Hopkins experience with 1278 patients. Medicine (Baltimore) 78(4), 270–283 (1999).
  • Craven CM , AllredT, GarrySL, PickrellJ, BuysSS: Three cases of fatal cardiac tamponade following ventricular endocardial biopsy.Arch. Pathol. Lab. Med., 114(8), 836–839 (1990).
  • Grzeskowiak R , WittH, Drungowski,Met al..: Expression profiling of human idiopathic dilated cardiomyopathy. Cardiovasc. Res., 59(2), 400–411 (2003).
  • Liew CC : Expressed genome molecular signatures of heart failure.Clin. Chem. Lab. Med., 43(5), 462–469 (2005).
  • Twine NC , StoverJA, Marshall,Bet al..: Disease-associated expression profiles in peripheral blood mononuclear cells from patients with advanced renal cell carcinoma. Cancer Res., 63(18), 6069–6075 (2003).
  • DePrimo SE , WongLM, KhatryDBet al..: Expression profiling of blood samples from an SU5416 Phase III metastatic colorectal cancer clinical trial: a novel strategy for biomarker identification. BMC. Cancer, 3(1), 3 (2003).
  • Horwitz PA , TsaiEJ, PuttMEet al..: Detection of cardiac allograft rejection and response to immunosuppressive therapy with peripheral blood gene expression. Circulation, 110(25), 3815–3821 (2004).
  • Ma J , LiewCC: Gene profiling identifies secreted protein transcripts from peripheral blood cells in coronary artery disease.J. Mol. Cell Cardiol., 35(8), 993–998 (2003).
  • Seo D , WangT, DressmanHet al..: Gene expression phenotypes of atherosclerosis. Arterioscler. Thromb. Vasc. Biol., 24(10), 1922–1927 (2004).
  • Kittleson M , HurwitzS, ShahMRet al..: Development of circulatory-renal limitations to angiotensin-converting enzyme inhibitors identifies patients with severe heart failure and early mortality. J. Am. Coll. Cardiol., 41(11), 2029–2035 (2003).
  • Felker GM , BenzaRL, ChandlerABet al..: Heart failure etiology and response to milrinone in decompensated heart failure: results from the OPTIME-CHF study. J. Am. Coll. Cardiol., 41(6), 997–1003 (2003).
  • Doval HC , NulDR, GrancelliHOet al..: Randomised trial of low-dose amiodarone in severe congestive heart failure. Grupo de Estudio de la Sobrevida en la Insuficiencia Cardiaca en Argentina (GESICA). Lancet, 344(8921), 493–498 (1994).
  • Singh SN , FletcherRD, FisherSGet al..: Amiodarone in patients with congestive heart failure and asymptomatic ventricular arrhythmia. Survival Trial of Anti-arrhythmic Therapy in Congestive Heart Failure. N. Engl. J. Med., 333(2), 77–82 (1995).
  • Taylor AL , ZiescheS, YancyCet al..: Combination of isosorbide dinitrate and hydralazine in blacks with heart failure. N. Engl. J. Med., 351(20), 2049–2057 (2004).
  • Lowes BD , GilbertEM, AbrahamWTet al..: Myocardial gene expression in dilated cardiomyopathy treated with β-blocking agents. N. Engl. J.Med., 346(18), 1357–1365 (2002).
  • Feenstra J , GrobbeeDE, RemmeWJ, StrickerBHC: Drug-induced heart failure.J. Am. Coll. Cardiol., 33(5), 1152–1162 (1999).
  • Kadish A : Prophylactic Defibrillator Implantation - Toward an Evidence-Based Approach.N. Engl. J. Med., 352(3), 285–287 (2005).
  • McClellan MB, Tunis SR: Medicare Coverage of ICDs. N. Engl. J. Med., 352(3), 222–224 (2005).

Websites

  • National heart, lung & blood institute www.cardiogenomics.org (Accessed October 2005)
  • Affymetrix company website www.affymetrix.com (Accessed October 2005)

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