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Aging Health Volume 4, 2008 - Issue 5
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Review

Vulval Complaints in Postmenopausal Women

S Gupta1 Benenden Hospital, Department of Gynaecology, Cranbrook, Kent, TN17 4AX, UK. [email protected]Correspondence[email protected]
View further author information
&
A B MacLean2 Royal Free Hospital, 10 Pond Street, Belsize Park, London, NW3 2QG, UK. [email protected]View further author information
Pages 543-552 | Published online: 26 Sep 2008

Bibliography

  • Bronstein J , PascalB, AbramoviciH: The common problems of vulvar pruritis.Obstet. Gynecol. Surv.48(2), 111–118(1993).
  • Barhan S , EzenaguL: Vulvar problems in elderly women. Don‘t assume that menopause is the culprit.Postgrad. Med.102(3), 121–125(1997).
  • Martin-Alguacil N , PfaffDW, KowLM, SchoberJM: Oestrogen receptors and their relation to neural receptive tissue of the labia minora.BJU Int.101(11), 1401–1406(2008).
  • Semmens JP , TsiaCC, SemmensECet al.: Effects of estrogen therapy on vaginal physiology during menopause. Obstet. Gynecol.66(1), 15–18(1985).
  • Ohman H , VahlquistA: In vivo studies concerning a pH gradient in human stratum corneum and upper dermis.Acta Derm. Venereol.74, 375–379(1994).
  • Summers PR . Hunn J: Unique dermatologic aspects of the postmenopausal vulva. Clin. Obstet. Gynecol.50(3), 745–751(2007).
  • Edwards NJ , MorrisHB: Langerhans’ cells and lymphocyte subsets in female genital tract.Br. J. Obstet. Gynaecol.92, 927–982(1985).
  • Nomura I , GolevaE, HowellMDet al.: Cytokine milieu of atopic dermatitis, as compared to psoriasis, skin prevents induction of innate immune response genes. J. Immunol.171, 3262–3269(2003).
  • Elsner P , WilhelmD, MiabachHI: Physiological skin surface water loss dynamics of human vulvar and forearm skin.Acta Derm. Venereol.70, 141–144(1990).
  • ACOG practice bulletin No. 93: Diagnosis and management of vulvar skin disorders. Obstet. Gynecol.111(5), 1243–1253(2008).
  • Farage MA : Vulvar susceptibility to contact irritants and allergens: a review.Arch. Gynecol. Obstet.272(2), 167–172(2005).
  • Farage MA , MillerKW, BerardescaZ, MaibachHI: Incontinence in the aged: contact dermatitis and other cutaneous consequences.Contact Derm.57(4), 211–217(2007).
  • Farage MA : A behind the scene look at the safety assessment of feminine hygiene pads. Annals of the New York Academy of sciences. Women‘s health and disease: gynecologic, endocrine, and reproductive issues. 1092(1), 66–77(2006).
  • Farage MA , StadlerA: Cumulative irritation patch test of sanitary pads on sensitive skin.J. Cosmet. Dermatol.4(3), 179–183(2005).
  • Ayhan A , Guvendag Guven ES, Guven S, Sakinci M, Kucukali T: Medical treatment of vulvar squamous cell hyperplasia. Int. J. Gynaecol. Obstet.95(3), 278–283(2006).
  • Soper JT , CreasmanWT: Vulvar dystrophies.Clin. Obstet. Gynecol.29, 431–439(1986).
  • Kaufman RH , GardnerHL, BrownD Jr, Beyth Y: Vulvar dystrophies: an evaluation. Am. J. Obstet. Gynecol.120, 363–367(1974).
  • Barbero M , MichelettiL, BorgnoG, CavannaL, PretiM, GhiringhelloB: Vulvar dystrophies in young and premenopausal women.J. Reprod. Med.33, 555–558(1988).
  • Clark TJ , EtheringtonIJ, LuesleyDM: Response of vulvar lichen sclerosus and squamous cell hyperplasia to graduated topical steroids,J. Reprod. Med.44, 958–962(1999).
  • Trimble CL , HildesheimA, BrintonLAet al.: Heterogenous etiology of squamous carcinoma of the vulva. Obstet. Gynecol.87, 59–64(1996).
  • Carli P , CattaneoA, De Magnis A, Biggeri A, Taddei G, Giannotti B: Squamous carcinoma arising in vulval lichen sclerosis: a cohort study. Eur. J. Cancer Prev.4, 491–495(1995).
  • Zamirska A , ReichA, Berny-MorenoJ, SalomonJ, SzepietowskiJC: Vulvar pruritus and burning sensation in women with psoriasis.Acta Derm. Venereol.88(2), 132–135(2008).
  • Simpkin S , OakleyA: Clinical review of 202 patients with vulval lichen sclerosus: a possible association with psoriasis.Australas. J. Dermatol.48(1), 28–31(2007).
  • Powell JJ , WojnarowskaF: Lichen sclerosus.Lancet353, 1777 (1999).
  • Powell J , RobsonA, CranstonD, WojnarowskaF, TurnerR: High incidence of lichen sclerosus in patients with squamous cell carcinoma of the penis.Br. J. Dermatol.145, 85–89(2001).
  • Leibowitch M , NeillS, PelisseM, Moyal-BaraccoM: The epithelial changes associated with squamous cell carcinoma of the vulva: a review of the clinical, histological and viral findings in 78 women.Br. J. Obstet. Gynaecol.97, 1135–1139(1990).
  • Harrington CI , DunsmoreIR: An investigation into the incidence of autiimmune disorders in patients with lichen sclerosus et atrophicus.Br. J. Dermatol.104, 563–566(1981).
  • Meyrick Thomas RH , RidleyCM, McGibbon DH, Black MM: Lichen sclerosus et atrophicus and autoimmunity – a study of 350 women. Br. J. Dermatol.118, 41 (1988).
  • Di Paolo GR , Rueda-LeveroneNG, Belardi MG: Lichensclerosis of the vulva recurrent after myocutaneous graft. A case report. J. Reprod. Med.27, 666–668(1982).
  • Warrington SA , De San Lazaro C: Lichensclerosus and sexual abuse. Arch. Dis. Child.75, 512–516(1996).
  • Purcell KG , SpencerLU, SimpsonPM Helman SW, Oldfather JW, Fowler JF Jr: HLA antigens in lichen sclerosus et atrophicus. Arch. Dermatol.126, 1043–1045(1990).
  • Friedrich EG Jr, Kalra PS: Serum levels of sex hormones in vulvar lichen sclerosis, and the effect of topical testosterone. N. Engl. J. Med.310(8), 488–491(1984).
  • Val I , AlmeidaG: An overview of lichen sclerosus.Clin. Obstet. Gynecol.48, 808 (2005).
  • Kiss A , CsontaiA, PirotL, NyiradyP, MerkszM, KiralyL: The response of balanitis xerotica obliterans to local steroid application compared with placebo in children.J. Urol.165, 219 (2001).
  • Das S , TunuguntlaHS: Balanitis xerotica obliterans – a review.World J. Urol.18, 382–387(2000).
  • Bracco GL , CarliP, SonniLet al.: Clinical and histologic effects of topical treatments of vulval lichen sclerosus. A critical evaluation. J. Reprod. Med.38, 37–40(1993).
  • Neill SM , TatnallFM, CoxNH: British Association of Dermatologists. Guidelines for the management of lichen sclerosus.Br. J. Dermatol.147, 640–649(2002).
  • Jones RW , ScurryJ, NeillSet al.: Guidelines for the follow-up of women with vulvar lichen sclerosus in specialist clinics. Am. J. Obstet. Gynecol.198, 496.E1–496.E3 (2008).
  • Rouzier R , HaddadB, DeyrolleC, Pelisse M, Moyal-Barracco M, Paniel BJ: Perineoplasty for the treatment of introital stenosis related to vulvar lichen sclerosus. Am. J. Obstet. Gynecol.186, 49–52(2002).
  • Brown LJR : Pathology of preinvasive lesions of the vulva. In: Cancer and Precancer of the Vulva. Luesley DM (Ed.). Hodder Arnold Publication, London, UK, 2, 14–29(2000).
  • Mann MS , KaufmanRH: Erosive lichen planus of the vulva.Clin. Obstet. Gynecol.34, 605–613(1991).
  • Kennedy CM , GalaskRP: Erosive vulvar lichen planus: retrospective review of characteristics and outcomes in 113 patients seen in a vulvar specialty clinic.J. Reprod. Med.52(1), 43–47(2007).
  • Belfiore P , Di Fede O, Cabibi D et al.: Prevalence of vulval lichen planus in a cohort of women with oral lichen planus: an interdisciplinary study. Br. J. Dermatol.155(5), 994–998(2006).
  • Di Fede O , BelfioreP, CabibiDet al.: Unexpectedly high frequency of genital involvement in women with clinical and histological features of oral lichen planus. Acta Derm. Venereol.86(5), 433–438(2006).
  • Frutos R , RodríguezS, Miralles-JordaL, MachucaG: Oral manifestations and dental treatment in menopause.Med. Oral7(1), 26–30, 31–35 (2002).
  • Silverman S , GorskyM, Lozada-NurF: A prospective follow up study of 570 patients of oral lichen planus: persistence, remission and malignant association.Oral Surg. Oral Med. Oral Pathol.60, 30–34(1985).
  • Frank MJ , YoungAW: Squamous cell carcinoma in situ arising within lichen planus vulva.Dermatol. Surg.21, 890–894(1995).
  • Dwyer CXM , KerrRE, MillanDW: Squamous carcinoma following lichen planus of the vulva.Clin. Exp. Dermatol.20, 171–172(1995).
  • Byrd JA , DavisMDP, BruceAJ, DrageLA, RogersRS III: Response of oral lichen planus to topical tacrolimus in 37 patients. Arch. Dermatol.140, 1508–1512(2004).
  • Thomson MA , HamburgerJ, StewartDG, LewisHM: Treatment of erosive oral lichen planus with topical tacrolimus.J. Dermatolog. Treat.15(5), 308–314(2004).
  • Kortekangas-Savolainen O , KiilholmaP: Treatment of vulvovaginal erosive and stenosing lichen planus by surgical dilatation an methotrexate.Acta Obstet. Gynecol. Scand.86(3), 339–343(2007).
  • Akerman G , DussourC, HaddadB, Paniel BJ, Rouzier R: Epidemiology of vulvar intra-epithelial neoplasias. Gynecol. Obstet. Fertil.35(12), 1251–1256(2007).
  • van Poelgeest MI , van Seters M, van Beurden M et al.: Detection of human papillomavirus (HPV) 16-specific CD4+ T-cell immunity in patients with persistent HPV16-induced vulvar intraepithelial neoplasia in relation to clinical impact of imiquimod treatment. Clin. Cancer Res.11(14), 5273–5280(2005).
  • Lininger RA , TavassoliFA: The pathology of vulvar neoplasia.Curr. Opin. Obstet. Gynecol.8(1), 63–68(1996).
  • Joura EA , LoschA, Haider-AngelerMG, BreiteneckerG, LeodolterS: Trends in vulvar neoplasia. Increasing incidence of vulvar intraepithelial neoplasia and squamous cell carcinoma of the vulva in young women.J. Reprod. Med.45(8), 613–615(2000).
  • Mulvany NJ , AllenDG: Differentiated intraepithelial neoplasia of the vulva.Int. J. Gynecol. Pathol.27(1), 125–135(2008).
  • Mathiesen O , BuusSK, CramersM: Topical imiquimod can reverse vulvar intraepithelial neoplasia: a randomised, double-blinded study.Gynecol. Oncol.107(2), 219–222(2007).
  • van Seters M , van Beurden M, ten Kate FJ et al.: Treatment of vulvar intraepithelial neoplasia with topical imiquimod. N. Engl. J. Med.358(14), 1465–1473(2008).
  • MacLean AB , MakwanaM, EllisPE, Cunniington: The management of Paget‘s disease of the vulva. J. Obstet. Gynecol.24(2), 124–128(2004).
  • Ellis PE , CanoSD, FearMet al.: Reduced E-cadherin expression correlates with disease progression in Paget‘s disease of the vulva but not Paget‘s disease of the breast. Mod. Pathol. DOI: 10.1038/modpathol.2008.50 (2008) (Epub ahead of print).
  • MacLean AB : Paget‘s disease of the vulva.J. Obstet. Gynecol.20(1), 7–9(2000).
  • Hatch KD , DavisJR: Complete resolution of Paget disease of the vulva with imiquimod cream.J. Low. Genit. Tract Dis.12(2), 90–94(2008).
  • Cohen PR , SchulzeKE, TschenJA, HetheringtonGW, NelsonBR: Treatment of extramammary Paget disease with topical imiquimod cream: case report and literature review.South. Med. J.99(4), 396–402(2006).
  • Haefner HK , CollinsME, DavisGDet al.: The vulvodynia guideline. J. Low. Genit. Tract Dis.9, 40–51(2005).
  • Tympanidis P , TerenghiG, DowdP: Increased innervation of the vulval vestibule in patients with vulvodynia.Br. J. Dermatol.148, 1021–1027(2003).
  • Bowen AR , VesterA, MarsdenL, Florell SR, Sharp H, Summers P: The role of vulvar skin biopsy in the evaluation of chronic vulvar pain. Am. J. Obstet. Gynecol. (2008) (Epub ahead of print).
  • Jelovsek JE , WaltersMD, BarberMD: Psychosocial impact of chronic vulvovagina conditions.J. Reprod. Med.53(2), 75–82(2008).
  • Gardella B , PorruD, FerdeghiniFet al.: Insight into urogynecologic features of women with interstitial cystitis/painful bladder syndrome. Eur. Urol. DOI: 10.1016/j.eururo.2008.01.079 (2008) (Epub ahead of print).
  • Peters K , GirdlerB, CarricoD, IbrahimI, DioknoA: Painful bladder syndrome/interstitial cystitis and vulvodynia: a clinical correlation.Int. Urogynecol. J. Pelvic Floor Dysfunct.19(5), 665–669(2008).
  • Harris G , HorowitzB, BorgidaA: Evaluation of gabapentin in the treatment of generalized vulvodynia, unprovokedJ. Reprod. Med.52(2), 103–106(2007).
  • Murina F , BernorioR, PalmiottoR: The use of amielle vaginal trainers as adjuvant in the treatment of vestibulodynia: an observational multicentric study.Medscape J. Med.10(1), 23 (2008).
  • Kamdar N , FisherL, MacNeillC: Improvement in vulvar vestibulitis with montelukast.J. Reprod. Med.52(10), 912–916(2007).
  • Zawislak AA , McCarronPA, McCluggage WG et al.: Novel bioadhesive patch-type system for photodynamic vulvodynia therapy after delivery of 5-aminolevulinic acid: preliminary evaluation. J. Reprod. Med.52(7), 645–653(2007).
  • Tobin J , HarindraV: Atrophic vulvovaginitis in women aged 50 years and above, both current and non-users of hormone replacement therapy, attending a genitourinary medicine clinic.J. Fam. Plann. Reprod. Health Care28(3), 135–136(2002).
  • North American Menopause Society: The role of local vaginal estrogen for treatment of vaginal atrophy in postmenopausal women: 2007 position statement of the North American Menopause Society. Menopause14(3), 355–369(2007).
  • Bygdeman M , SwahnML: Replens vs dienoestrol cream in the symptomatic treatment of vaginal atrophy in postmenopausal women.Maturitas23, 259–263(1996).
  • Sobel JD : Recurrent vulvovaginal candiasis: aprospective study of the efficacy of maintainance ketoconazole therapy.N. Engl. J. Med.315(23), 1455–1458(1986).
  • Sobel JD : Pathogenesis and treatment of recurrent vulvovaginal candiasis.Clin. Infect. Dis.14(Suppl. 1), S148–S153 (1992).
  • Ventolini G , BaggishMS, WalshPM: Vulvovaginal candidiasis from non-albicans species: retrospective study of recurrence rate after fluconazole therapy.J. Reprod. Med.51(6), 475–478(2006).
  • Sobel JD , WiesenfeldHC, MartensMet al.: Maintenance fluconazole therapy for recurrent vulvovaginal candidiasis. N. Engl. J. Med.351(9), 876–883(2004).
  • Lynch PJ , Moyal-BarroccoM, BogliattoF, MichelettiL, ScurryJ: 2006 ISSVD classification of vulvar dermatoses: pathologic subsets and their clinical correlates.J. Reprod. Med.52(1), 3–9(2007).
  • Lynch PJ : 2006 International Society for the Study of Vulvovaginal Disease classification of vulvar dermatoses: a synopsis.J. Low. Genit. Tract Dis.11(1), 1–2(2007).
  • Sideri M , JonesRW, WilkinsonEJJ: Squamous vulvar intraepithelial neoplasia: 2004 modified terminology, ISSVD Vulvar Oncology Subcommittee.Reprod. Med.50(11), 807–810(2005).

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