The Relationship Between Serum Lactate Dehydrogenase Level and Mortality in Critically Ill Patients

References

• Randhawa VK , GrunauBE, DebickiDBet al. Cardiac intensive care unit management of patients after cardiac arrest: now the real work begins. Canadian J. Cardiol.34(2), 156–167 (2018).
   PubMed Web of Science ®Google Scholar
• Narendra DK , HessDR, SesslerCNet al. Update in management of severe hypoxemic respiratory failure. Chest152(4), 867–879 (2017).
   PubMed Web of Science ®Google Scholar
• Tisherman SA , SteinDM. ICU management of trauma patients. Crit. Care Med.46(12), 1991–1997 (2018).
   PubMed Web of Science ®Google Scholar
• Webster KA , DischerDJ, HernandezOM, YamashitaK, BishopricNH. A glycolytic pathway to apoptosis of hypoxic cardiac myocytes. Molecular pathways of increased acid production. Adv. Exp. Med. Biol.475, 161–175 (2000).
   PubMed Web of Science ®Google Scholar
• Dawson DM , GoodfriendTL, KaplanNO. Lactic dehydrogenases: functions of the two types pates of synthesis of the two major forms can be correlated with metabolic differentiation. Science143(3609), 929–933 (1964).
   PubMedGoogle Scholar
• Markert CL . Lactate dehydrogenase. Biochemistry and function of lactate dehydrogenase. Cell Biochem. Function2(3), 131–134 (1984).
   PubMed Web of Science ®Google Scholar
• Storey KB . Comparative enzymology-new insights from studies of an ‘old’ enzyme, lactate dehydrogenase. Comp. Biochem. Physiol. B Biochem. Mol. Biol.199, 13–20 (2016).
   PubMed Web of Science ®Google Scholar
• Xie J , ChengC, JieYet al. Expression of lactate dehydrogenase is induced during hypoxia via HIF-1 in the mud crab Scylla paramamosain. Comp. Biochem. Physiol. C Toxicol. Pharmacol.225, 108563 (2019).
   PubMed Web of Science ®Google Scholar
• Drent M , CobbenNA, HendersonRF, WoutersEF, van Dieijen-VisserM. Usefulness of lactate dehydrogenase and its isoenzymes as indicators of lung damage or inflammation. Eur. Respir. J.9(8), 1736–1742 (1996).
   PubMed Web of Science ®Google Scholar
• Karlsson M , DungKT, ThiTLet al. Lactate dehydrogenase as an indicator of severe illness in neonatal intensive care patients: a longitudinal cohort study. Acta Paediatr.101(12), 1225–1231 (2012).
   PubMed Web of Science ®Google Scholar
• Gaspar P , Al-BayatiFA, AndrewPW, NevesAR, YesilkayaH. Lactate dehydrogenase is the key enzyme for pneumococcal pyruvate metabolism and pneumococcal survival in blood. Infect. Immun.82(12), 5099–5109 (2014).
   PubMed Web of Science ®Google Scholar
• Mura M , AndradeCF, HanBet al. Intestinal ischemia-reperfusion-induced acute lung injury and oncotic cell death in multiple organs. Shock28(2), 227–238 (2007).
   PubMed Web of Science ®Google Scholar
• Jurisic V , RadenkovicS, KonjevicG. The actual role of LDH as tumor marker, biochemical and clinical aspects. Adv. Exp. Med. Biol.867, 115–124 (2015).
   PubMed Web of Science ®Google Scholar
• Wu LW , KaoTW, LinCMet al. Examining the association between serum lactic dehydrogenase and all-cause mortality in patients with metabolic syndrome: a retrospective observational study. BMJ Open6(5), e011186 (2016).
   PubMed Web of Science ®Google Scholar
• Hu EC , HeJG, LiuZHet al. High levels of serum lactate dehydrogenase correlate with the severity and mortality of idiopathic pulmonary arterial hypertension. Experiment. Therapeut. Med.9(6), 2109–2113 (2015).
   PubMed Web of Science ®Google Scholar
• Yamaguchi S , AbeM, ArakakiT, ArasakiO, ShimabukuroM. Prognostic value of lactate dehydrogenase for mid-term mortality in acute decompensated heart failure: a comparison to established biomarkers and brain natriuretic peptide. Heart Lung Circ.29(9), 1318–1327 (2020).
   PubMed Web of Science ®Google Scholar
• Lu J , WeiZ, JiangHet al. Lactate dehydrogenase is associated with 28-day mortality in patients with sepsis: a retrospective observational study. J. Surg. Res.228, 314–321 (2018).
   PubMed Web of Science ®Google Scholar
• Coskun R , GundoganK, SezginGCet al. A retrospective review of intensive care management of organophosphate insecticide poisoning: single center experience. Nigerian J. Clin. Pract.18(5), 644–650 (2015).
   PubMed Web of Science ®Google Scholar
• Schmidt JJ , LueckC, ZiesingSet al. Clinical course, treatment and outcome of Pneumocystis pneumonia in immunocompromised adults: a retrospective analysis over 17 years. Crit. Care22(1), 307 (2018).
   PubMedGoogle Scholar
• Moon KM , HanMS, RimCBet al. Risk factors for mechanical ventilation in patients with scrub typhus admitted to intensive care unit at a university hospital. Tuberculosis Respir. Dis.79(1), 31–36 (2016).
   Google Scholar
• Goldberger AL , AmaralLA, GlassLet al. PhysioBank, PhysioToolkit and PhysioNet: components of a new research resource for complex physiologic signals. Circulation101(23), E215–E220 (2000).
   PubMed Web of Science ®Google Scholar
• Pollard TJ , JohnsonAEW, RaffaJD, CeliLA, MarkRG, BadawiO. The eICU Collaborative Research Database, a freely available multi-center database for critical care research. Sci. Data5, 180178 (2018).
   PubMed Web of Science ®Google Scholar
• Danpure CJ . Lactate dehydrogenase and cell injury. Cell Biochem. Function2(3), 144–148 (1984).
   PubMed Web of Science ®Google Scholar
• Li H , XiongW, LiuHet al. Serum LDH level may predict outcome of chronic lymphocytic leukemia patients with a 17p deletion: a retrospective analysis of prognostic factors in China. Chinese J. Cancer Res.29(2), 156–165 (2017).
   PubMed Web of Science ®Google Scholar
• Deme D , TelekesA. [Prognostic importance of lactate dehydrogenase (LDH) in oncology]. Orvosi Hetilap.158(50), 1977–1988 (2017).
   PubMed Web of Science ®Google Scholar
• Mishra D , BanerjeeD. Lactate dehydrogenases as metabolic links between tumor and stroma in the tumor microenvironment. Cancers11(6), 750 (2019).
   PubMed Web of Science ®Google Scholar
• Ding J , KarpJE, EmadiA. Elevated lactate dehydrogenase (LDH) can be a marker of immune suppression in cancer: interplay between hematologic and solid neoplastic clones and their microenvironments. Cancer Biomark.19(4), 353–363 (2017).
   PubMed Web of Science ®Google Scholar
• Helliksson F , WernermanJ, WiklundL, RosellJ, KarlssonM. The combined use of three widely available biochemical markers as predictor of organ failure in critically ill patients. Scand. J. Clin. Lab. Invest.76(6), 479–485 (2016).
   PubMed Web of Science ®Google Scholar
• Cecconi M , EvansL, LevyM, RhodesA. Sepsis and septic shock. Lancet392(10141), 75–87 (2018).
   PubMed Web of Science ®Google Scholar
• Bennett CE , WrightRS, JentzerJet al. Severity of illness assessment with application of the APACHE IV predicted mortality and outcome trends analysis in an academic cardiac intensive care unit. J. Crit. Care50, 242–246 (2019).
   PubMed Web of Science ®Google Scholar