Wnt/β-Catenin Pathway Proteins in End-Stage Renal Disease

References

• Makris K , SpanouL. Acute kidney injury: definition, pathophysiology and clinical phenotypes. Clin. Biochem. Rev.37(2), 85–98 (2016).
   PubMedGoogle Scholar
• Levey AS , CoreshJ, BoltonKet al. K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification. Am. J. Kidney Dis.39(Suppl 1. 2), S1–S266 (2002).
   PubMed Web of Science ®Google Scholar
• Abbasi MA , ChertowGM, HallYN. End-stage renal disease. BMJ Clin. Evid.2002, 2010 (2010).
   Google Scholar
• Johansen KL , ChertowGM, FoleyRNet al. US Renal Data System 2020 Annual Data Report: Epidemiology of Kidney Disease in the United States (2021). A7A8774. Am J Kidney Dis77(4), A7–A8 (2021).
   PubMed Web of Science ®Google Scholar
• Milinković N , SarićM, JovičićS, MirkovićD, LežaićV, IgnjatovićS. Lipid status association with 25-hydroxy vitamin D: cross sectional study of end-stage renal disease patients. J. Med. Biochem.39(3), 309–317 (2020).
   PubMed Web of Science ®Google Scholar
• Babaei M , DashtiN, LameiNet al. Evaluation of plasma concentrations of homocysteine, IL-6, TNF-α, HS-CRP, and total antioxidant capacity in patients with end-stage renal failure. Acta Med. Iran52(12), 893–898 (2014).
   PubMedGoogle Scholar
• Oweis AO , Al-QarqazF, BodoorKet al. Elevated interleukin 31 serum levels in hemodialysis patients are associated with uremic pruritus. Cytokine138, 155369 (2021).
   PubMed Web of Science ®Google Scholar
• Almeida A , GajewskaK, DuroM, CostaF, PintoE. Trace element imbalances in patients undergoing chronic hemodialysis therapy - report of an observational study in a cohort of Portuguese patients. J. Trace Elem. Med. Biol.62, 126580 (2020).
   PubMed Web of Science ®Google Scholar
• Dizdar OS , YıldızA, GulCB, GunalAI, ErsoyA, GundoganK. The effect of hemodialysis, peritoneal dialysis and renal transplantation on nutritional status and serum micronutrient levels in patients with end-stage renal disease; multicenter, 6-month period, longitudinal study. J. Trace Elem. Med. Biol.60, 126498 (2020).
   PubMed Web of Science ®Google Scholar
• Sangeetha Lakshmi B , HariniDevi N, SuchitraMM, SrinivasaRao P, SivaKumar V. Changes in the inflammatory and oxidative stress markers during a single hemodialysis session in patients with chronic kidney disease. Ren. Fail.40(1), 534–540 (2018).
   PubMed Web of Science ®Google Scholar
• Song YR , KimJK, LeeHS, KimSG, ChoiEK. Serum levels of protein carbonyl, a marker of oxidative stress, are associated with overhydration, sarcopenia and mortality in hemodialysis patients. BMC Nephrol.21(1), 281 (2020).
   PubMed Web of Science ®Google Scholar
• Alicic RZ , RooneyMT, TuttleKR. Diabetic kidney disease: challenges, progress, and possibilities. Clin. J. Am. Soc. Nephrol.12(12), 2032–2045 (2017).
   PubMed Web of Science ®Google Scholar
• Weldegiorgis M , WoodwardM. The impact of hypertension on chronic kidney disease and end-stage renal disease is greater in men than women: a systematic review and meta-analysis. BMC Nephrol.21(1), 506 (2020).
   PubMed Web of Science ®Google Scholar
• Capone D , VinciguerraM, RagostaA, CitroV, TarantinoG. Troponin levels relate to CRP concentrations in patients with NAFLD on maintenance haemodialysis: a retrospective study. Adv. Ther.37(7), 3337–3347 (2020).
   PubMed Web of Science ®Google Scholar
• Wang S , SongK, SrivastavaRet al. Nonalcoholic fatty liver disease induced by noncanonical Wnt and its rescue by Wnt3a. FASEB J.29(8), 3436–3445 (2015).
   PubMed Web of Science ®Google Scholar
• Clevers H , NusseR. Wnt/β-catenin signaling and disease. Cell149(6), 1192–1205 (2012).
   PubMed Web of Science ®Google Scholar
• Logan CY , NusseR. The Wnt signaling pathway in development and disease. Annu. Rev. Cell Dev. Biol.20, 781–810 (2004).
   PubMed Web of Science ®Google Scholar
• Das S , YuS, SakamoriR, StypulkowskiE, GaoN. Wntless in Wnt secretion: molecular, cellular and genetic aspects. Front. Biol.7(6), 587–593 (2012).
   Google Scholar
• Duncan AR , GonzálezDP, DelViso F, RobsonA, KhokhaMK, GriffinJN. Alkylglycerol monooxygenase, a heterotaxy candidate gene, regulates left-right patterning via Wnt signaling. Developm. Biol.456(1), 1–7 (2019).
   PubMed Web of Science ®Google Scholar
• Schwab KR , PattersonLT, HartmanHAet al. Pygo1 and Pygo2 roles in Wnt signaling in mammalian kidney development. BMC Biol.5, 15–15 (2007).
   PubMed Web of Science ®Google Scholar
• Angers S , MoonRT. Proximal events in Wnt signal transduction. Nature Rev. Mol. Cell Biol.10(7), 468–477 (2009).
   PubMed Web of Science ®Google Scholar
• Duan P , BonewaldLF. The role of the wnt/β-catenin signaling pathway in formation and maintenance of bone and teeth. Int. J. Biochem. Cell Biol.77(Pt A), 23–29 (2016).
   PubMedGoogle Scholar
• Kawakami T , RenS, DuffieldJS. Wnt signalling in kidney diseases: dual roles in renal injury and repair. J. Pathol.229(2), 221–231 (2013).
   PubMed Web of Science ®Google Scholar
• Wang Y , ZhouCJ, LiuY. Wnt Signaling in kidney development and disease. Progr. Mol. Biol. Transl. Sci.153, 181–207 (2018).
   PubMed Web of Science ®Google Scholar
• Sun W , MeednuN, RosenbergAet al. B cells inhibit bone formation in rheumatoid arthritis by suppressing osteoblast differentiation. Nat. Comm.9(1), 1–14 (2018).
   PubMedGoogle Scholar
• Bafico A , LiuG, YanivA, GazitA, AaronsonSA. Novel mechanism of Wnt signalling inhibition mediated by Dickkopf-1 interaction with LRP6/Arrow. Nat. Cell Biol.3(7), 683–686 (2001).
   PubMed Web of Science ®Google Scholar
• Reinhold S , BlankesteijnWM. Wnt/β-catenin inhibitor Dickkopf 1: a novel predictor for cardiovascular and cerebrovascular events. Arterioscl. Thromb. Vasc. Biol.39, 121–123 (2019).
   PubMed Web of Science ®Google Scholar
• Ke HZ , RichardsWG, LiX, OminskyMS. Sclerostin and Dickkopf-1 as therapeutic targets in bone diseases. Endocr. Rev.33(5), 747–783 (2012).
   PubMed Web of Science ®Google Scholar
• Bouquegneau A , EvenepoelP, PaquotF, MalaiseO, CavalierE, DelanayeP. Sclerostin within the chronic kidney disease spectrum. Clin. Chim. Acta502, 84–90 (2020).
   PubMed Web of Science ®Google Scholar
• Cejka D , MarculescuR, KozakowskiNet al. Renal elimination of sclerostin increases with declining kidney function. J. Clin. Endocrinol. Metabol.99(1), 248–255 (2014).
   PubMed Web of Science ®Google Scholar
• Cejka D , Jäger-LanskyA, KiewegHet al. Sclerostin serum levels correlate positively with bone mineral density and microarchitecture in haemodialysis patients. Nephrol. Dial. Transpl.27(1), 226–230 (2012).
   PubMed Web of Science ®Google Scholar
• Thambiah S , RoplekarR, ManghatPet al. Circulating sclerostin and Dickkopf-1 (DKK1) in predialysis chronic kidney disease (CKD): relationship with bone density and arterial stiffness. Calcif. Tissue Int.90(6), 473–480 (2012).
   PubMed Web of Science ®Google Scholar
• Qureshi AR , OlausonH, WitaspAet al. Increased circulating sclerostin levels in end-stage renal disease predict biopsy-verified vascular medial calcification and coronary artery calcification. Kidney Int.88(6), 1356–1364 (2015).
   PubMed Web of Science ®Google Scholar
• Lee H , SeidlC, SunR, GlinkaA, NiehrsC. R-spondins are BMP receptor antagonists in Xenopus early embryonic development. Nat. Comm.11(1), 5570–5570 (2020).
   PubMed Web of Science ®Google Scholar
• Binnerts ME , KimKA, BrightJMet al. R-Spondin1 regulates Wnt signaling by inhibiting internalization of LRP6. Proc. Natl Acad. Sci. USA104(37), 14700–14705 (2007).
   PubMed Web of Science ®Google Scholar
• Clevers H , LohKM, NusseR. An integral program for tissue renewal and regeneration: Wnt signaling and stem cell control. Science346(6205), (2014).
   PubMed Web of Science ®Google Scholar
• Lu W , KimKA, LiuJet al. R-spondin1 synergizes with Wnt3A in inducing osteoblast differentiation and osteoprotegerin expression. FEBS Lett.582(5), 643–650 (2008).
   PubMed Web of Science ®Google Scholar
• Nelson WJ , NusseR. Convergence of Wnt, beta-catenin, and cadherin pathways. Science303(5663), 1483–1487 (2004).
   PubMed Web of Science ®Google Scholar
• Li V , NgS, BoersemaPet al. Wnt signaling inhibits proteasomal b-catenin degradation within a compositionally intact Axin1 complex. Cell149, 1245–1256 (2012).
   PubMed Web of Science ®Google Scholar
• Niehrs C . The complex world of WNT receptor signalling. Nature Rev. Mol. Cell. Biol.13(12), 767–779 (2012).
   PubMed Web of Science ®Google Scholar
• Duchartre Y , KimYM, KahnM. The Wnt signaling pathway in cancer. Crit. Rev. Oncol. Hematol.99, 141–149 (2016).
   PubMed Web of Science ®Google Scholar
• Yu J , CarrollTJ, RajagopalJ, KobayashiA, RenQ, McmahonAP. A Wnt7b-dependent pathway regulates the orientation of epithelial cell division and establishes the cortico-medullary axis of the mammalian kidney. Development136(1), 161–171 (2009).
   PubMed Web of Science ®Google Scholar
• Schmidt-Ott KM , BaraschJ. WNT/beta-catenin signaling in nephron progenitors and their epithelial progeny. Kidney Int.74(8), 1004–1008 (2008).
   PubMed Web of Science ®Google Scholar
• Iglesias DM , HueberPA, ChuLet al. Canonical WNT signaling during kidney development. Am. J. Physiol. Renal. Physiol.293(2), F494–500 (2007).
   PubMed Web of Science ®Google Scholar
• He W , KangYS, DaiC, LiuY. Blockade of Wnt/β-catenin signaling by paricalcitol ameliorates proteinuria and kidney injury. J. Am. Soc. Nephrol.22(1), 90–103 (2011).
   PubMed Web of Science ®Google Scholar
• Von Toerne C , SchmidtC, AdamsJet al. Wnt pathway regulation in chronic renal allograft damage. Am. J. Transplant.9(10), 2223–2239 (2009).
   PubMed Web of Science ®Google Scholar
• Dai C , StolzDB, KissLP, MongaSP, HolzmanLB, LiuY. Wnt/beta-catenin signaling promotes podocyte dysfunction and albuminuria. J. Am. Soc. Nephrol.20(9), 1997–2008 (2009).
   PubMed Web of Science ®Google Scholar
• Surendran K , SchiaviS, HruskaKA. Wnt-dependent beta-catenin signaling is activated after unilateral ureteral obstruction, and recombinant secreted frizzled-related protein 4 alters the progression of renal fibrosis. J. Am. Soc. Nephrol.16(8), 2373–2384 (2005).
   PubMed Web of Science ®Google Scholar
• Enooku K , KondoM, FujiwaraNet al. Hepatic IRS1 and ß-catenin expression is associated with histological progression and overt diabetes emergence in NAFLD patients. J. Gastroenterol.53(12), 1261–1275 (2018).
   PubMed Web of Science ®Google Scholar
• Levey AS , CoreshJ, GreeneTet al. Expressing the Modification of Diet in Renal Disease Study equation for estimating glomerular filtration rate with standardized serum creatinine values. Clin. Chem.53(4), 766–772 (2007).
   PubMed Web of Science ®Google Scholar
• Behets GJ , ViaeneL, MeijersBet al. Circulating levels of sclerostin but not DKK1 associate with laboratory parameters of CKD-MBD. PLoS ONE12(5), e0176411 (2017).
   PubMed Web of Science ®Google Scholar
• Kim SH , YoonSY, LimS-K, RheeY. The effect of renal dysfunction on circulating sclerostin level in patients with Type 2 diabetes. Int. J. Endocrinol.2014, 715908 (2014).
   PubMed Web of Science ®Google Scholar
• Pelletier S , DubourgL, CarlierM-C, Hadj-AissaA, FouqueD. The relation between renal function and serum sclerostin in adult patients with CKD. Clin. J. Am. Soc. Nephrol.8(5), 819–823 (2013).
   Web of Science ®Google Scholar
• Bonani M , RodriguezD, FehrTet al. Sclerostin blood levels before and after kidney transplantation. Kidney Blood Press. Res.39(4), 230–239 (2014).
   PubMed Web of Science ®Google Scholar
• Fang Y , GinsbergC, SeifertMet al. CKD-induced wingless/integration1 inhibitors and phosphorus cause the CKD-mineral and bone disorder. J. Am. Soc. Nephrol.25(8), 1760–1773 (2014).
   PubMed Web of Science ®Google Scholar
• Byrne CD , TargherG. NAFLD as a driver of chronic kidney disease. J. Hepatol.72(4), 785–801 (2020).
   PubMed Web of Science ®Google Scholar
• Aoki J , IkariY. Cardiovascular disease in patients with end-stage renal disease on hemodialysis. Ann. Vasc. Dis.10(4), 327–337 (2017).
   PubMedGoogle Scholar
• Novo-Rodríguez C , García-FontanaB, Luna-DelCastillo JDet al. Circulating levels of sclerostin are associated with cardiovascular mortality. PLoS ONE13(6), e0199504 (2018).
   PubMed Web of Science ®Google Scholar
• Kim KI , ParkKU, ChunEJet al. A novel biomarker of coronary atherosclerosis: serum DKK1 concentration correlates with coronary artery calcification and atherosclerotic plaques. J. Korean Med. Sci.26(9), 1178–1184 (2011).
   PubMed Web of Science ®Google Scholar
• Polyzos SA , AnastasilakisAD, KountourasJet al. Circulating sclerostin and Dickkopf-1 levels in patients with nonalcoholic fatty liver disease. J. Bone Miner. Metab.34(4), 447–456 (2016).
   PubMed Web of Science ®Google Scholar
• Chen C , ZhuD, ZhangHet al. YAP-dependent ubiquitination and degradation of β-catenin mediates inhibition of Wnt signalling induced by Physalin F in colorectal cancer. Cell Death Dis.9(6), 591 (2018).
   PubMedGoogle Scholar
• Thorstensen L , LotheRA. The WNT signaling pathway and its role in human solid tumors. Atlas Genet. Cytogenet. Oncol. Haematol.7(2), 144–159 (2003).
   Google Scholar
• Claes KJ , ViaeneL, HeyeS, MeijersB, D'haeseP, EvenepoelP. Sclerostin: another vascular calcification inhibitor?J. Clin. Endocrinol. Metabol.98(8), 3221–3228 (2013).
   PubMed Web of Science ®Google Scholar
• Clevers H . Wnt/beta-catenin signaling in development and disease. Cell127(3), 469–480 (2006).
   PubMed Web of Science ®Google Scholar
• He W , DaiC, LiY, ZengG, MongaSP, LiuY. Wnt/beta-catenin signaling promotes renal interstitial fibrosis. J. Am. Soc. Nephrol.20(4), 765–776 (2009).
   PubMed Web of Science ®Google Scholar
• Hao S , HeW, LiYet al. Targeted inhibition of β-catenin/CBP signaling ameliorates renal interstitial fibrosis. J. Am. Soc. Nephrol.22(9), 1642–1653 (2011).
   PubMed Web of Science ®Google Scholar
• Dirocco DP , KobayashiA, TaketoMM, McmahonAP, HumphreysBD. Wnt4/β-catenin signaling in medullary kidney myofibroblasts. J. Am. Soc. Nephrol.24(9), 1399–1412 (2013).
   PubMed Web of Science ®Google Scholar
• El Sebaie MH , ArafatMA, FawzyMS, SalemIM. The effect of renal dysfunction on circulating sclerostin level in patients with Type 2 diabetes. Zagazig Univ. Med. J.27(1), 58–69 (2021).
   Google Scholar
• Cejka D , HerberthJ, BranscumAJet al. Sclerostin and Dickkopf-1 in renal osteodystrophy. Clin. J. Am. Soc. Nephrol.6(4), 877–882 (2011).
   PubMed Web of Science ®Google Scholar
• Malluche HH , DavenportDL, CantorT, Monier-FaugereMC. Bone mineral density and serum biochemical predictors of bone loss in patients with CKD on dialysis. Clin. J. Am. Soc. Nephrol.9(7), 1254–1262 (2014).
   PubMed Web of Science ®Google Scholar
• Baetta R , BanfiC. Dkk (Dickkopf) Proteins. Arterioscl. Thromb. Vasc. Biol.39(7), 1330–1342 (2019).
   PubMed Web of Science ®Google Scholar
• Ueland T , OtterdalK, LekvaTet al. Dickkopf-1 enhances inflammatory interaction between platelets and endothelial cells and shows increased expression in atherosclerosis. Atertioscl. Thromb. Vasc. Biol.29(8), 1228–1234 (2009).
   PubMed Web of Science ®Google Scholar
• Holmes D . Sclerostin levels linked to CKD outcomes. Nature Rev. Endocrinol.10(10), 577–577 (2014).
   PubMedGoogle Scholar
• Kanbay M , SiriopolD, SaglamMet al. Serum sclerostin and adverse outcomes in nondialyzed chronic kidney disease patients. J. Clin. Endocrinol. Metabol.99(10), E1854–1861 (2014).
   PubMed Web of Science ®Google Scholar
• Yang C-Y , ChangZ-F, ChauY-Pet al. Circulating Wnt/β-catenin signalling inhibitors and uraemic vascular calcifications. Nephrol. Dial. Transpl.30(8), 1356–1363 (2015).
   PubMed Web of Science ®Google Scholar
• Morena M , JaussentI, DupuyAMet al. Osteoprotegerin and sclerostin in chronic kidney disease prior to dialysis: potential partners in vascular calcifications. Nephrol. Dial. Transplant.30(8), 1345–1356 (2015).
   PubMed Web of Science ®Google Scholar
• Lv W , GuanL, ZhangY, YuS, CaoB, JiY. Sclerostin as a new key factor in vascular calcification in chronic kidney disease stages 3 and 4. Int. Urol. Nephrol.48(12), 2043–2050 (2016).
   PubMed Web of Science ®Google Scholar
• Desjardins L , LiabeufS, OliveiraRBet al. Uremic toxicity and sclerostin in chronic kidney disease patients. Nephrol. Ther.10(6), 463–470 (2014).
   PubMed Web of Science ®Google Scholar
• Navarro-Alarcon M , Reyes-PérezA, Lopez-GarciaH, Palomares-BayoM, Olalla-HerreraM, Lopez-MartinezMC. Longitudinal study of serum zinc and copper levels in hemodialysis patients and their relation to biochemical markers. Biol. Trace Elem. Res.113(3), 209–222 (2006).
   PubMed Web of Science ®Google Scholar
• Tonelli M , WiebeN, HemmelgarnBet al. Trace elements in hemodialysis patients: a systematic review and meta-analysis. BMC Med.7, 25 (2009).
   PubMed Web of Science ®Google Scholar
• Hasanato RM . Assessment of trace elements in sera of patients undergoing renal dialysis. Saudi Med. J.35(4), 365–370 (2014).
   PubMed Web of Science ®Google Scholar
• Ari E , KayaY, DemirH, AsiciogluE, KeskinS. The correlation of serum trace elements and heavy metals with carotid artery atherosclerosis in maintenance hemodialysis patients. Biol. Trace Elem. Res.144(1–3), 351–359 (2011).
   PubMed Web of Science ®Google Scholar
• Hsieh YY , ShenWS, LeeLY, WuTL, NingHC, SunCF. Long-term changes in trace elements in patients undergoing chronic hemodialysis. Biol. Trace Elem. Res.109(2), 115–121 (2006).
   PubMed Web of Science ®Google Scholar
• Gómez De Oña C , Martínez-MorilloE, GagoGonzález E, Vidau ArgüellesP, FernándezMerayo C, ÁlvarezMenéndez FV. Variation of trace element concentrations in patients undergoing hemodialysis in the north of Spain. Scand. J. Clin. Lab. Invest.76(6), 492–499 (2016).
   PubMed Web of Science ®Google Scholar
• Ahmadipour F , MahjoubS, PouramirM, SiahposhtA, AfsharNaderi A, AbsalanA. Determining serum zinc and magnesium levels in hemodialysis patients could be helpful for clinicians. Indian J. Clin. Biochem.32(4), 464–467 (2017).
   PubMedGoogle Scholar
• Hirano T , MurakamiM, FukadaT, NishidaK, YamasakiS, SuzukiT. Roles of zinc and zinc signaling in immunity: zinc as an intracellular signaling molecule. Adv. Immunol.97, 149–176 (2008).
   PubMed Web of Science ®Google Scholar
• Batista MN , CuppariL, DeFátima Campos Pedrosa Let al. Effect of end-stage renal disease and diabetes on zinc and copper status. Biol. Trace Elem. Res.112(1), 1–12 (2006).
   PubMed Web of Science ®Google Scholar
• Liu J , CuiY, ShiL, LuanJ, ZhouX, HanJ. A cellular model for Wilson's disease using patient-derived induced pluripotent stem cells revealed aberrant β-catenin pathway during osteogenesis. Biochem. Biophys. Res. Commun.513(2), 386–391 (2019).
   PubMed Web of Science ®Google Scholar
• Xu J , ZhangR, ZhangTet al. Copper impairs zebrafish swimbladder development by down-regulating Wnt signaling. Aquat. Toxicol.192, 155–164 (2017).
   PubMed Web of Science ®Google Scholar