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Perspective

LDL-C or apoB as the best target for reducingcoronary heart disease: should apoB be implemented into clinical practice?

Pages 35-48 | Published online: 18 Jan 2017

Bibliography

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  • The ‘apoB paradigm’ states that the rate at which LDL particles are produced is at least as important a determinant of their concentration in plasma as the rate at which they are cleared from plasma, and that secretion of cholesterol within VLDL particles is an important mechanism of maintaining cholesterol homoeostasis within the hepatocyte.
  • Davidson MH: Novel nonstatin strategies to lower low-density lipoprotein cholesterol. Curr. Atheroscler. Rep. 11, 67–70 (2011).

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